Conclusions
The microcirculation is a key element in tissue oxygenation, as it is where most of oxygen and nutrient exchanges take place. Studying the microcirculation in humans has long been difficult as laser-Doppler or plethysmography techniques do not take into account heterogeneity of blood flow. OPS imaging techniques allow direct visualisation of the human microcirculation. Using this approach, we demonstrated that the sublingual microcirculation of patients with acute circulatory failure is markedly altered. In addition, rapid improvement of the microcirculation, which occurred well before an improvement in systemic haemodynamics, was predictive of a good outcome. These alterations are not influenced by arterial pressure or vasopressor agents and cannot be detected by classical monitoring devices. Monitoring the microcirculation of patients with acute circulatory failure may help to identify those patients in whom further interventions may be required.
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de Backer, D. (2005). Orthogonal polarisation spectral imaging: principles, techniques, human studies. In: Gullo, A. (eds) Anaesthesia, Pain, Intensive Care and Emergency Medicine — A.P.I.C.E.. Springer, Milano. https://doi.org/10.1007/88-470-0351-2_48
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DOI: https://doi.org/10.1007/88-470-0351-2_48
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