Is CRT Useful in Patients with Atrial Fibrillation?
It may be said that CRT has a role in improving functional capacity over conventional right ventricular pacing in patients with left ventricular failure who require permanent ventricular stimulation and/or in those with an indication for AV nodal ablation. As for the great majority of patients with advanced heart failure and AF without conventional indications for permanent cardiac pacing — a wide and progressively expanding population in the “border zone” of current indications for CRT — no definite data are available. Some promising results from ablated patients show a favourable trend in major cardiac event reduction after CRT. More controlled clinical data are required to achieve definite conclusions about the indications for CRT in heart failure patients with AF.
KeywordsAtrial Fibrillation Sinus Rhythm Cardiac Resynchronisation Therapy Atrial Fibrillation Patient Ventricular Pace
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- 7.Middelkauf HR, Stevenson WG, Stevenson LW (1991) Prognostic significance of atrial fibrillation in advanced heart failure. A study of 390 patients. Circulation 84:40–48Google Scholar
- 14.Puggioni E, Brignole M, Gammage M et al (2004) Acute comparative effect of right and left ventricular pacing in patients with permanent atrial fibrillation. Circulation 43:234–238Google Scholar
- 20.Doshi R for PAVE study group (2004) The Left Ventricular-Based Cardiac Stimulation Post AV Nodal Ablation Evaluation Study. Late breaking clinical trials, ACC 8 March, New Orleans, LAGoogle Scholar