Timing and Typology of Cardio-Embolic Prevention in Patients with Atrial Fibrillation
OAT currently represents the most effective therapy for cardio-embolic prevention in patients with non-valvular AF at moderate-to-high risk. Antiplatelet therapy may represent an alternative for low-risk patients or patients who are poor candidates for OAT, due to a high risk of bleeding or limited compliance. The hope for the future is the development of newer alternatives to OAT with a more convenient pharmacological profile, less risk of bleeding and easier management . At present, oral direct thrombin inhibitors seem the most promising alternatives, but further studies are needed to confirm their safety.
KeywordsAtrial Fibrillation International Normalise Ratio Stroke Prevention Atrial Fibrillation Patient Left Atrial Appendage
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