Advertisement

Mechanical Behavior and Properties of Adipose Tissue

  • Cees OomensEmail author
  • Gerrit Peters
Chapter
  • 1.1k Downloads
Part of the Studies in Mechanobiology, Tissue Engineering and Biomaterials book series (SMTEB, volume 16)

Abstract

This chapter gives an overview of work on porcine adipose tissue that was performed at Eindhoven University of Technology. It demonstrates that only at very small strains, far away from the physiological strains we experience in daily live, the behavior is more or less linear and can be described with standard constitutive models. Long term oscillatory behavior and the behavior at large strains is more complex and currently a highly unexplored area. Adipose tissue is able to change its micro-structure such that at high strains or long times of harmonic excitation the material behavior changes drastically. This structural change is reversible after long periods of rest. The chapter is largely based on two papers by Geerligs et al. [3, 4].

Keywords

Adipose Tissue Shear Strain Pressure Ulcer Harmonic Excitation Loss Modulo 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Comley, K., Fleck, N.: The compressive response of porcine adipose tissue from low to high strain rate. Int. J. Impact. Eng. 46, 1–10 (2012)CrossRefGoogle Scholar
  2. 2.
    Elsner, J.J., Gefen, A.: Is obesity a risk factor for deep tissue injury inpatients with spinal cord injury? J. Biomech. 41, 3322–3331 (2008)CrossRefGoogle Scholar
  3. 3.
    Geerligs, M., Peters, G.W.M., Ackermans, P.A.J., Oomens, C.W.J., Baaijens, F.P.T.: Linear viscoelastic behavior of subcutaneous adipose tissue. Biorheology 45(6), 677–688 (2008)Google Scholar
  4. 4.
    Geerligs, M., Peters, G.W.M., Ackermans, P.A., Oomens, C.W., Baaijens, F.P.: Does subcutaneous adipose tissue behave as an (anti)-thixotropic material. J. Biomech. 43(6), 1153–1159 (2010)CrossRefGoogle Scholar
  5. 5.
    Gefen, A., Haberman, E.: Viscoelastic properties of ovine adipose tissue covering the gluteus muscles. J. Biomech. Eng. 129, 924–930 (2007)CrossRefGoogle Scholar
  6. 6.
    Gennisson, J.L., Baldeweck, T., Tanter, M., Catheline, S., Fink, M., Sandrin, L., Cornillon, C., Querleux, B.: Assessment of elastic parameters of human skin using dynamic elastography. IEEE Trans. Ultrason. Ferroelectr. Freq. Control 51, 980–989 (2004)CrossRefGoogle Scholar
  7. 7.
    Hrapko, M., van Dommelen, J.A., Peters, G.W.M., Wismans, J.S.: The mechanical behavior of brain tissue: large strain response and constitutive modeling. Biorheology 43, 623–636 (2006)Google Scholar
  8. 8.
    Iatridis, J.C., Wu, J., Yandow, J.A., Langevin, H.M.: Subcutaneous tissue mechanical behavior is linear and viscoelastic under uniaxial tension. Connect. Tissue Res. 44, 208–217 (2003)CrossRefGoogle Scholar
  9. 9.
    Klein, J., Permana, P.A., Owecki, M., Chaldakov, G.N., Bohm, M., Hausman, G., Lapiere, C.M., Atanassova, P., Sowinski, J., Fasshauer, M., Hausman, D.B., Maquoi, E., Tonchev, A.B., Peneva, V.N., Vlachanov, K.P., Fiore, M., Aloe, L., Slominski, A., Reardon, C.L., Ryan, T.J., Pond, C.M.: What are subcutaneous adipocytes really good for …? Exp. Dermatol. 16, 45–70 (2007)CrossRefGoogle Scholar
  10. 10.
    Krouskop, T.A., Wheeler, T.M., Kallel, F., Garra, B.S., Hall, T.: Elastic moduli of breast and prostate tissues under compression. Ultrason. Imaging 20, 260–274 (1998)CrossRefGoogle Scholar
  11. 11.
    Linder-Ganz, E., Shabshin, N., Itzchak, Y., Gefen, A.: Assessment of mechanical conditions in sub-dermal tissues during sitting: A combined experimental-MRI and finite element approach. J. Biomech. 40, 1443–1454 (2007)Google Scholar
  12. 12.
    O’Neill, P.L., Stachowiak, G.W.: The inverse thixotropic behavior of synovial fluid and its relation to the lubrication of synovial joints. J. Orthop. Rheumatol. 9, 222–228 (1996)Google Scholar
  13. 13.
    Oomens, C.W.J., Bressers, O.F.J.T., Bosboom, E.M.H., Bouten, C.V.C., Bader, D.L.: Can loaded interface characteristics influence strain distributions in muscle adjacent to bony prominences. Comp. Meth. Biomech. Biomed. Eng. 6(3), 171–180 (2003)CrossRefGoogle Scholar
  14. 14.
    Oomens, C.W.J., Zenhorst, W., Broek, M., Hemmes, B., Poeze, M., Brink, P.R.G., Bader, D.L.: A nuemrical study to analyse the risk for pressure ulcer development on a spine board. Clin. Biomech. 28, 736–742 (2013)CrossRefGoogle Scholar
  15. 15.
    Patel, P.N., Smith, C.K., Patrick, C.W.: Rheological and recovery properties of poly (ethylene glycol) diacrylate hydrogels and human adipose tissue. J. Biomed. Mater. Res. Part A 73A, 313–319 (2005)CrossRefGoogle Scholar
  16. 16.
    Samani, A., Plewes, D.: A method to measure the hyperelastic parameters of ex vivo breast tissue samples. Phys. Med. Biol. 49, 4395–4405 (2004)CrossRefGoogle Scholar
  17. 17.
    Samani, A., Zubovits, J., Plewes, D.: Elastic moduli of normal and pathological human breast tissues: an inversion-technique-based investigation of 169 samples. Phys. Med. Biol. 52, 1565–1576 (2007)CrossRefGoogle Scholar
  18. 18.
    Sarvazyan, A.P., Skovoroda, A., Emelianov, S.: Biophysical bases of elasticity imaging. Acoust. Imaging 21, 223–240 (1995)Google Scholar
  19. 19.
    Van Dam, E.A., Dams, S.D., Peters, G.W.M., Rutten, M.C., Schurink, G.W., Buth, J., Van de Vosse, F.N.: Non-linear viscoelastic behavior of abdominal aortic aneurysm thrombus. Biomech. Model. Mechanobiol. 7, 127–137 (2008)CrossRefGoogle Scholar
  20. 20.
    Van Houten, E.E., Doyley, M.M., Kennedy, F.E., Weaver, J.B., Paulsen, K.D.: Initial in vivo experience with steady-state subzone-based MR elastography of the human breast. J. Magn. Reson. Imaging 17, 72–85 (2003)CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Eindhoven University of TechnologyEindhovenThe Netherlands

Personalised recommendations