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Behavioral Pharmacology of Neuropeptides: Oxytocin pp 389–420Cite as

Oxytocin and Interpersonal Relationships

Part of the Current Topics in Behavioral Neurosciences book series (CTBN,volume 35)

Abstract

The neuropeptide oxytocin (OT) has emerged as a potent modulator of diverse aspects of interpersonal relationships. OT appears to work in close interaction with several other neurotransmitter networks, including the dopaminergic reward circuit, and to be dependent on sex-specific hormonal influences. In this chapter, we focus on four main domains of OT and interpersonal relationships, including (1) the protective effect of OT on an individual’s ability to withstand stress (i.e., stress buffering), (2) the effect of OT on emotion recognition and empathy, (3) OT’s ability to enhance social synchrony and cooperation among individuals, and (4) the effect of OT on an individual’s perception of social touch. We then illustrate the connection between OT and loneliness while grieving the loss of a loved one. We finish by discussing the clinical potential of OT, focusing on its potential role as an adjunct to psychotherapy, its enhancement through sex-specific hormonal influences, and the difficulties that present themselves when considering OT as a therapy. Overall, we argue that OT continues to hold strong therapeutic promise, but that it is strongly dependent on internal and external influences, for instance the patient’s personal past experiences and interaction with the therapist, in order to provide the best possible therapy.

Keywords

  • Oxytocin
  • Psychotherapy
  • Social relationship
  • Social synchrony
  • Social touch
  • Stress

A. Patin and D. Scheele share first authorship.

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  • DOI: 10.1007/7854_2017_22
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  1. Department of Psychiatry, Division of Medical Psychology, University of Bonn – Medical Center, Sigmund-Freud-Str. 25, 53105, Bonn, Germany

    Alexandra Patin, Dirk Scheele & Rene Hurlemann

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  1. Alexandra Patin
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  2. Dirk Scheele
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  3. Rene Hurlemann
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Correspondence to Rene Hurlemann .

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  1. Department of Psychiatry, University of Bonn, Bonn, Nordrhein-Westfalen, Germany

    Rene Hurlemann

  2. Schaller Research Group on Neuropeptides German Cancer Research Center, University of Heidelberg, Heidelberg, BW, Germany

    Valery Grinevich

  3. Central Institute of Mental Health, University of Heidelberg, Mannheim, BW, Germany

    Valery Grinevich

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Patin, A., Scheele, D., Hurlemann, R. (2017). Oxytocin and Interpersonal Relationships. In: Hurlemann, R., Grinevich, V. (eds) Behavioral Pharmacology of Neuropeptides: Oxytocin. Current Topics in Behavioral Neurosciences, vol 35. Springer, Cham. https://doi.org/10.1007/7854_2017_22

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