The Functional and Structural Neuroanatomy of Systems Consolidation for Autobiographical and Semantic Memory

  • Adam J. O. Dede
  • Christine N. Smith
Part of the Current Topics in Behavioral Neurosciences book series (CTBN, volume 37)


It is well established that patients with memory impairment have more difficulty retrieving memories from the recent past relative to the remote past and that damage to the medial temporal lobe (MTL) plays a key role in this pattern of impairment. The precise role of the MTL and how it may interact with other brain regions remains an area of active research. We investigated the role of structures in a memory network that supports remembering. Our chapter focuses on two types of memory: episodic memory and semantic memory. Findings from studies of patients with brain damage and neuroimaging studies in patients and healthy individuals were considered together to identify the functional and structural neuroanatomy of past remembrance.


Retrograde amnesia Autobiographical memory Semantic memory Connectivity Neuroimaging Lesion Patient 


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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  1. 1.Department of PsychologyUniversity of California San DiegoSan DiegoUSA
  2. 2.Department of PsychiatryUniversity of California San DiegoSan DiegoUSA
  3. 3.Veteran Affairs San Diego Healthcare SystemSan DiegoUSA

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