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Role of Heat Shock Factor 1 in HIV

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Heat Shock Proteins in Inflammatory Diseases

Part of the book series: Heat Shock Proteins ((HESP,volume 22))

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Abbreviations

AIDS:

acquired immune deficiency syndrome

AP-1:

activator protein 1

APOBEC3G:

apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G

BRG1:

brahma related gene 1

CaMK II:

calcium/calmodulin-dependent protein kinase II

CBP:

CREB-binding protein

CHIP:

carboxy terminus of Hsp70-binding protein

CK2:

casein kinase 2

CREB:

cyclic AMP response element-binding protein

DBD:

deoxyribonucleic acid binding domain

ELL2:

eleven nineteen lysine-rich leukemia gene

ER stress:

endoplasmic reticulum stress

FACT:

facilitates chromatin transcription

GM-CSF:

granulocyte-macrophage colony-stimulating factor

HAART:

highly active antiretroviral therapy

HADCi:

histone deacetylase inhibitors

HIV:

human immunodeficiency virus

HO-1:

heme oxygenase-1

HR:

heptad repeats

HSE:

heat shock element

HSF1:

heat shock factor 1

HSFs:

heat shock factors

Hsp:

heat shock proteins

Hsp90:

heat shock protein 90

HSR:

heat shock response

IKKγ:

IκB phosphorylation kinase γ

LEDGF:

lens epithelial-derived growth factor

LEF-1:

lymphoid enhancer-binding factor 1

LPS:

lipopolysaccharide

LRAs:

latency reversing agents

LTR:

long terminal repeat

MAPK:

mitogen-activated protein kinase

MNSF-β:

monoclonal nonspecific suppressor factor β

mTOR:

mammalian target of rapamycin

NF-AT:

nuclear factor of activated T cells

NF-κB:

nuclear factor kappa-B

PARP1:

poly (ADP-ribose) polymerase 1

PIC:

preintegration complex

PIs:

proteasome inhibitors

PKA:

protein kinase A

PKC:

protein kinase C

PLK1:

polo-like kinase 1

PPARγ:

peroxisome proliferation activated receptor γ

PSMD:

26S proteasome non-ATPase regulatory subunit

p-TEFb:

positive transcription elongation factor b

REACT:

reiterative enrichment and authentication of CRISPRi targets

RPA:

replication protein A

SIRT1:

sirtuin1

SIV:

simian immunodeficiency virus

Sp1:

specificity protein 1

STAT5:

signal transducer and activator of transcription 5

TAD:

transcriptional activation domain

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Acknowledgements

Authors thank Dr. Shibo Jiang at Fudan University, China, for providing the essential cell lines used in the experiment. This study was funded by Natural Science of China (grant number 31370781 and 81773787), the National S&T Key Special foundation (2014ZX09509001-004), the Natural Science Foundation of Guangdong Province (S201102005207) and National Science and Technology Major Project (2018ZX10301101).

Disclosure of Interests

All authors declare they have no conflict of interest.

Ethical Approval for Studies Involving Humans

This article does not contain any studies with human participants performed by any of the authors.

Ethical Approval for Studies Involving Animals

This article does not contain any studies with animals performed by any of the authors.

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Authors and Affiliations

  1. Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China

    Xinfeng Xu & Shuwen Liu

  2. State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Science, Wuhan, China

    Xiaoyan Pan

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  1. Xinfeng Xu
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  2. Xiaoyan Pan
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  3. Shuwen Liu
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Correspondence to Shuwen Liu .

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  1. Department of Medicine and Precision Therapeutics Proteogenomics Diagnostic Center, Eleanor N. Dana Cancer Center University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA

    Alexzander A. A. Asea

  2. Department of Medicine and Precision Therapeutics Proteogenomics Diagnostic Center, Eleanor N. Dana Cancer Center University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA

    Punit Kaur

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Xu, X., Pan, X., Liu, S. (2020). Role of Heat Shock Factor 1 in HIV. In: Asea, A.A.A., Kaur, P. (eds) Heat Shock Proteins in Inflammatory Diseases. Heat Shock Proteins, vol 22. Springer, Cham. https://doi.org/10.1007/7515_2020_11

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