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New Biomass Reagents for the Synthesis of Bioactive Compounds

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Flow Chemistry in Drug Discovery

Part of the book series: Topics in Medicinal Chemistry ((TMC,volume 38))

Abstract

In this chapter we discuss the possibility of using biomass as reagents for the synthesis of biologically active compounds. The selected examples only scratch the surface on the volume of research being carried out on the topics, but are significant of its strengths and challenges. As is delineated below, the data collected so far offers significant support for the continuation of an interdisciplinary research for the development of new pharmaceutically relevant products from biomass.

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Author information

Authors and Affiliations

  1. KelAda Pharmachem Ltd., Dublin, Ireland

    Karen Fox

  2. Departamento de Quimica Organica, Universidad de Cordoba, Cordoba, Spain

    Karen Fox & Rafael Luque

  3. Department of Pharmacy, Health Sciences Faculty, University of Brasília, Brasília, DF, Brazil

    Luiz Antonio Soares Romeiro

  4. LADETER, Catholic University of Brasilia, Brasília, DF, Brazil

    Luiz Antonio Soares Romeiro

  5. Department of Pharmacy and Biotechnology, Bologna, Italy

    Maria Laura Bolognesi

Authors
  1. Karen Fox
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  2. Rafael Luque
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  3. Luiz Antonio Soares Romeiro
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  4. Maria Laura Bolognesi
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Corresponding authors

Correspondence to Rafael Luque or Maria Laura Bolognesi .

Editor information

Editors and Affiliations

  1. Discovery Chemistry, Janssen Pharmaceutical Companies of J&J, Janssen-Cilag, S.A., Toledo, Spain

    Jesus Alcazar

  2. Faculty of Chemistry, University of Castilla-La Mancha, Ciudad Real, Ciudad Real, Spain

    Antonio de la Hoz

  3. Faculty of Chemistry, University of Castilla-La Mancha, Ciudad Real, Spain

    Angel Díaz-Ortiz

Ethics declarations

Funding: MLB was supported by a grant of Visiting Professor (PVE-CNPq #401864/2013-8) from the program “Ciência sem Fronteiras”, Brazil National Council for Scientific and Technological Development (Grant CNPq 401864/2013-8). LASR is a fellow holder for Productivity in Technological Development and Innovative Extension – DT (CNPq 308486/2020-0).

Ethical Approval: This manuscript is a review of previously published accounts, as such, no animal or human studies were performed.

Informed Consent: No patients were studied in this chapter.

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Fox, K., Luque, R., Soares Romeiro, L.A., Bolognesi, M.L. (2021). New Biomass Reagents for the Synthesis of Bioactive Compounds. In: Alcazar, J., de la Hoz, A., Díaz-Ortiz, A. (eds) Flow Chemistry in Drug Discovery. Topics in Medicinal Chemistry, vol 38. Springer, Cham. https://doi.org/10.1007/7355_2021_118

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