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Removal and Degradation of Pharmaceutically Active Compounds in Wastewater Treatment pp 119–143Cite as

Perspectives on the Feasibility of Using Enzymes for Pharmaceutical Removal in Wastewater

Part of the The Handbook of Environmental Chemistry book series (HEC,volume 108)

Abstract

This particular chapter spotlights the growing environmental concerns and hazardous consequences of numerous organic contaminants so-called emerging contaminants (ECs). These ECs are being detected, though in different quantities, in different environmental matrices and wastewater treatment systems. With ever-increasing awareness, people are now more concerned about the wide-spread distribution of pharmaceutically related active compounds in water matrices. In turn, the free flow of ECs in water matrices poses notable adverse effects on human, aquatic animals, and naturally occurring plants, even at very small concentrations. Due to inadequacies and ineffectiveness of, in practice, physical and chemical-based remediation processes, robust treatment approaches, such as microorganisms and their novel enzyme-based degradation/removal of ECs, are of supreme interest. This chapter focuses on various pharmaceutically related ECs and their efficient mitigation from water matrices. Following a brief introduction, the focus is given to two main treatment approaches, i.e., (1) remediation of pharmaceutically active compounds by crude (pristine) and purified enzymes (i.e., lignin peroxidase, manganese peroxidase, soybean peroxidase, horseradish peroxidase, and laccases) and (2) immobilized enzyme-assisted degradation of pharmaceutically active compounds.

Keywords

  • Biocatalysis
  • Biological risks
  • Enzymes
  • Hazardous compounds
  • Toxicity
  • Wastewater treatment

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Acknowledgments

Authors are grateful to their representative universities/institutes for providing literature facilities.

Conflict of Interests

Authors declare no conflict of interest in any capacity, including financial and competing.

Author information

Authors and Affiliations

  1. School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huaian, China

    Muhammad Bilal

  2. Tecnologico de Monterrey, School of Engineering and Sciences, Monterrey, NL, Mexico

    Hafiz M. N. Iqbal

  3. Water and Soil Quality Research Group, Department of Environmental Chemistry, IDAEA-CSIC, Barcelona, Spain

    Damiá Barceló

  4. Catalan Institute for Water Research (ICRA), Girona, Spain

    Damiá Barceló

  5. College of Environmental and Resources Sciences, Zhejiang A&F University, Hangzhou, China

    Damiá Barceló

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  1. Muhammad Bilal
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  2. Hafiz M. N. Iqbal
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  3. Damiá Barceló
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Correspondence to Hafiz M. N. Iqbal .

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Editors and Affiliations

  1. Catalan Institute for Water Research (ICRA), University of Girona, Girona, Spain

    Sara Rodriguez-Mozaz

  2. Universitat Autònoma de Barcelona, Barcelona, Spain

    Paqui Blánquez Cano

  3. Universitat Autònoma de Barcelona, Barcelona, Spain

    Montserrat Sarrà Adroguer

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Bilal, M., Iqbal, H.M.N., Barceló, D. (2020). Perspectives on the Feasibility of Using Enzymes for Pharmaceutical Removal in Wastewater. In: Rodriguez-Mozaz, S., Blánquez Cano, P., Sarrà Adroguer, M. (eds) Removal and Degradation of Pharmaceutically Active Compounds in Wastewater Treatment. The Handbook of Environmental Chemistry, vol 108. Springer, Cham. https://doi.org/10.1007/698_2020_661

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