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Uptake and Translocation of Pharmaceuticals in Plants: Principles and Data Analysis

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Interaction and Fate of Pharmaceuticals in Soil-Crop Systems

Part of the book series: The Handbook of Environmental Chemistry ((HEC,volume 103))

Abstract

Pharmaceuticals originating from reclaimed wastewater or biosolid-, livestock manure- or sewage sludge-amended soils can enter crops by irrigation and fertilization. Generally, the putative uptake occurs through the plants’ roots and can lead to the bioaccumulation in different plant parts. The uptake and translocation therefore is dependent on multiple parameters, i.e. physicochemical properties of compounds, plant physiology and environmental factors. This book chapter combines a theoretical background on the main principles of uptake and translocation of pharmaceuticals by plants and a critical evaluation of current available literature, by analysing studies for the bioconcentration and translocation factors of different pharmaceutical groups in several plant species. Thereby, interesting results were obtained by looking at the translocation of various pharmaceuticals in radish and at cationic compounds in soil studies. Comparing the different studies, the relevance of testing not only high but also real environmental concentrations became obvious, since for some pharmaceuticals, higher uptake and translocation ratios were achieved with lower applied concentrations. Basic guidelines could provide a possibility to make scientific data more comparable and reliable and to avoid the exclusion of potential reasons for the missing uptake or translocation of pharmaceuticals. This book chapter provides recommendations for future research studies to generate more valid conclusions within the scientific community.

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Acknowledgements

This research was developed by the Water Joint Programming Initiative (WATER-JPI) of the European Research Area (ERA-NET). We would like to thank the responsible persons for raising the AWARE project and the Federal Office for Agriculture and Food (Projektträger Bundesanstalt für Landwirtschaft und Ernährung) (2816ERA04W), which also supported the author Y Bigott. DM Khalaf was granted by the Katholischer Akademischer Ausländer-Dienst (KAAD). C Cruzeiro was funded by the European project IDOUM (Water challenges for a changing world – IC4Water) as part of the WATER21015 JPI.

We thank Andreia Canito for providing us the coloured lettuce representation and Philip Schmode for helping us with data organization.

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Authors and Affiliations

  1. Research Unit Comparative Microbiome Analysis, Helmholtz Zentrum München German Research Center for Environmental Health, Neuherberg, Germany

    Yvonne Bigott, David Mamdouh Khalaf, Peter Schröder & Catarina Cruzeiro

  2. Botany and Microbiology Department, Faculty of Science, Assiut University, Assiut, Egypt

    David Mamdouh Khalaf

  3. Technical University of Munich, Freising, Germany

    Peter M. Schröder

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  1. Yvonne Bigott
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  2. David Mamdouh Khalaf
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  3. Peter Schröder
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  4. Peter M. Schröder
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  5. Catarina Cruzeiro
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Correspondence to Catarina Cruzeiro .

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Editors and Affiliations

  1. Department of Environmental and Food Chemistry (ENFOCHEM), Institute of Environmental Assessment and Water Research (IDAEA-CSIC), Barcelona, Spain

    Sandra Pérez Solsona

  2. Department of Environmental and Food Chemistry (ENFOCHEM), Institute of Environmental Assessment and Water Research (IDAEA-CSIC), Barcelona, Spain

    Nicola Montemurro

  3. University of Montpellier - IRD, Montpellier, France

    Serge Chiron

  4. Catalan Institute for Water Research (ICRA), Parc Científic i Tecnològic de la Universitat de Girona, Girona, Spain

    Damià Barceló

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Bigott, Y., Khalaf, D.M., Schröder, P., Schröder, P.M., Cruzeiro, C. (2020). Uptake and Translocation of Pharmaceuticals in Plants: Principles and Data Analysis. In: Pérez Solsona, S., Montemurro, N., Chiron, S., Barceló, D. (eds) Interaction and Fate of Pharmaceuticals in Soil-Crop Systems. The Handbook of Environmental Chemistry, vol 103. Springer, Cham. https://doi.org/10.1007/698_2020_622

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