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Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Enhance Angiogenesis Through Upregulation of the VWF and Flk1 Genes in Endothelial Cells

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Advances in Mesenchymal Stem Cells and Tissue Engineering (ICRRM 2023)

Part of the book series: Advances in Experimental Medicine and Biology ((ICRRM))

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Abbreviations

ANG1:

Angiopoietin 1

ANG2:

Angiopoietin 2

CD:

Cluster of differentiation

GFP:

Green fluorescent protein

HGF:

Hepatic growth factor

hUCMSC:

Human umbilical cord mesenchymal stem cells

HUVEC:

Human umbilical vein endothelial cells

PBS:

Phosphate buffer saline

PIGF:

Placental growth factor

TGF-β:

Transforming growth factor beta

VEGF:

Vascular endothelial growth factor

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Acknowledgments

We thank SCI Biobank for providing mesenchymal stem cells used in this study.

Author’s Contributions

All authors equally contributed in this work. All authors read and approved the final version of the manuscript for submission.

Availability of Data and Materials

Data and materials used and/or analyzed during the current study are available from the corresponding author on reasonable request.

Ethics Approval and Consent to Participate

Not applicable.

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Not applicable.

Competing Interests

The authors declare that they have no competing interests.

Funding

This research is funded by Vietnam National University, Ho Chi Minh City (VNU-HCM) under grant number 562-2020-18-03.

Author information

Authors and Affiliations

  1. Laboratory of Stem Cell Research and Application, University of Science, Ho Chi Minh City, Vietnam

    Phat Duc Huynh & Phuc Van Pham

  2. Vietnam National University, Ho Chi Minh City, Vietnam

    Phat Duc Huynh & Phuc Van Pham

  3. Stem Cell Institute, University of Science, Ho Chi Minh City, Vietnam

    Phuc Van Pham & Ngoc Bich Vu

  4. University of Science, Ho Chi Minh City, Vietnam

    Ngoc Bich Vu

Authors
  1. Phat Duc Huynh
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  2. Phuc Van Pham
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  3. Ngoc Bich Vu
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Corresponding author

Correspondence to Ngoc Bich Vu .

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Editors and Affiliations

  1. Stem Cells Institute, University of Science Viet Nam National University Ho Chi Minh City, Ho Chi Minh City, Vietnam

    Phuc Van Pham

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Huynh, P.D., Van Pham, P., Vu, N.B. (2023). Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Enhance Angiogenesis Through Upregulation of the VWF and Flk1 Genes in Endothelial Cells. In: Pham, P.V. (eds) Advances in Mesenchymal Stem Cells and Tissue Engineering. ICRRM 2023. Advances in Experimental Medicine and Biology(). Springer, Cham. https://doi.org/10.1007/5584_2023_768

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