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Therapeutic Efficacy of Mandibular Advancement Devices in Patients with Severe Sleep Apnea: A Preliminary Report

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Clinical Research Involving Pulmonary Disorders

Part of the book series: Advances in Experimental Medicine and Biology ((NR,volume 1040))

Abstract

Obstructive sleep apnea (OSA) is defined as episodes of upper airway obstructions during sleep. The method of choice in conservative treatment of OSA is the use of devices that produce positive airway pressure (CPAP). In patients with mild-moderate form of OSA, intraoral mandibular advancement devices (MAD) are applied. The aim of the study was to evaluate the therapeutic efficacy of MAD in patients with severe OSA who were unable to use CPAP. In this preliminary study three patients from a group of 25 severe OSA sufferers who failed to use CPAP, were included. The three patients underwent a triple polysomnographic (PSG) investigation: on CPAP, before MAD treatment, and during MAD. The patients completed the Epworth Sleepiness Scale questionnaire twice. We found significant improvements of subjective symptoms and PSG-evaluated variables after application of MAD in all three patients in comparison with both baseline and CPAP-recorded data. We conclude that MAD can be an alternative treatment option for severe OSA patients who are non-compliant with CPAP therapy.

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Conflicts of Interest

The authors declare no conflict of interest in relation to this article.

Author information

Authors and Affiliations

  1. Department of Prosthodontics, Medical University of Warsaw, 59 Nowogrodzka Street, Bldg.XIa, Warsaw, 02-006, Poland

    M. Wojda, J. Kostrzewa-Janicka, P. Jurkowski & E. Mierzwińska-Nastalska

  2. Fourth Clinic of Lung Diseases, Institute of Tuberculosis and Lung Diseases, Warsaw, Poland

    P. Bieleń

Authors
  1. M. Wojda
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  2. J. Kostrzewa-Janicka
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  3. P. Bieleń
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  4. P. Jurkowski
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  5. E. Mierzwińska-Nastalska
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Corresponding author

Correspondence to J. Kostrzewa-Janicka .

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Editors and Affiliations

  1. Opole Medical School, Opole, Poland

    Mieczyslaw Pokorski

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Wojda, M., Kostrzewa-Janicka, J., Bieleń, P., Jurkowski, P., Mierzwińska-Nastalska, E. (2017). Therapeutic Efficacy of Mandibular Advancement Devices in Patients with Severe Sleep Apnea: A Preliminary Report. In: Pokorski, M. (eds) Clinical Research Involving Pulmonary Disorders. Advances in Experimental Medicine and Biology(), vol 1040. Springer, Cham. https://doi.org/10.1007/5584_2017_101

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