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Hypertension: from basic research to clinical practice pp 419–426Cite as

Hypertension Is a Risk Factor for Several Types of Heart Disease: Review of Prospective Studies

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Part of the Advances in Experimental Medicine and Biology book series (AIM,volume 956)

Abstract

Many prospective cohort studies have demonstrated that hypertension is a strong risk factor for total mortality and cardiovascular disease (CVD). Heart disease includes coronary heart disease (CHD), heart failure, atrial fibrillation, valvular disease, sudden cardiac death (SCD), sick sinus syndrome (SSS), cardiomyopathy, and aortic aneurysms. Most of the epidemiologic prospective studies of heart disease focused on coronary/ischemic heart disease. Here we comprehensively reviewed the association between hypertension and the above-mentioned heart diseases. We found that CHD, heart failure, atrial fibrillation, aortic valvular disease, SCD, SSS, left ventricular hypertrophy, and abdominal aortic aneurysms were all associated with hypertension. Those relations tended to be stronger in men. The prevention of hypertension and lowering one’s blood pressure may help reduce the risk of developing heart disease.

Keywords

  • Heart disease
  • Hypertension
  • Prospective studies
  • Epidemiology
  • Risk factors

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Source of Funding

This work was supported by the Intramural Research Fund of the National Cerebral and Cardiovascular Center, by the Japan Agency for Medical Research and development, AMED (15gk0210001h0101), and by a Grant-in-Aid for Scientific Research (B, No. 16H05252) and Challenging Exploratory Research (No. 16K15365) in Japan.

Author information

Authors and Affiliations

  1. Department of Preventive Cardiology, National Cerebral and Cardiovascular Center, 5-7-1, Fujishiro-dai, Suita, Osaka, 565-8565, Japan

    Yoshihiro Kokubo

  2. Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan

    Chisa Matsumoto

Authors
  1. Yoshihiro Kokubo
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  2. Chisa Matsumoto
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Corresponding author

Correspondence to Yoshihiro Kokubo .

Editor information

Editors and Affiliations

  1. Department of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Stockholm, Sweden

    Md. Shahidul Islam

  2. Department of Internal Medicine and Emergency Medicine, Uppsala University Hospital, Uppsala, Sweden

    Md. Shahidul Islam

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Kokubo, Y., Matsumoto, C. (2016). Hypertension Is a Risk Factor for Several Types of Heart Disease: Review of Prospective Studies. In: Islam, M.S. (eds) Hypertension: from basic research to clinical practice. Advances in Experimental Medicine and Biology(), vol 956. Springer, Cham. https://doi.org/10.1007/5584_2016_99

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  • DOI: https://doi.org/10.1007/5584_2016_99

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-44250-1

  • Online ISBN: 978-3-319-44251-8

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