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Superimposed Preeclampsia

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Hypertension: from basic research to clinical practice

Part of the book series: Advances in Experimental Medicine and Biology ((AIM,volume 956))

Abstract

Superimposed preeclampsia refers to women with chronic arterial hypertension (primary or secondary) who develop preeclampsia (PE). Because hypertension affects 5–15 % of pregnancies, it is itself a matter of concern. However, this concern should be permanent, given the increased risk of the hypertension worsening and, particularly, the appearance of superimposed PE. The search for factors that underlie or promote the development of this disorder has been the subject of intense research. However, despite the wealth of knowledge, the cause or causes remain to be determined.

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Abbreviations

ACOG:

American College of Obstetricians and Gynecologists

eNOS:

endothelial nitric oxide synthase

IUGR:

intra-uterine growth restriction

LR:

likelihood ratio

NO:

nitric oxide

PE:

preeclampsia

PI:

pulsatility index

PlGF:

placental growth factor

sFlt-1:

soluble fms-like tyrosine kinase

sPE:

superimposed preeclampsia

UtA:

uterine artery

−ve:

negative

+ve:

positive

VEGF:

vascular endothelial growth factor.

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The author declares no conflicts of interest.

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Authors and Affiliations

  1. Department of Experimental Biology, Faculty of Medicine, University of Porto, 4200-319, Porto, Portugal

    Luís Guedes-Martins

  2. Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-319, Porto, Portugal

    Luís Guedes-Martins

  3. Departamento da Mulher e da Medicina Reprodutiva, Centro Hospitalar do Porto EPE, Largo Prof. Abel Salazar, 4099-001, Porto, Portugal

    Luís Guedes-Martins

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  1. Luís Guedes-Martins
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Correspondence to Luís Guedes-Martins .

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Editors and Affiliations

  1. Department of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Stockholm, Sweden

    Md. Shahidul Islam

  2. Department of Internal Medicine and Emergency Medicine, Uppsala University Hospital, Uppsala, Sweden

    Md. Shahidul Islam

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Guedes-Martins, L. (2016). Superimposed Preeclampsia. In: Islam, M.S. (eds) Hypertension: from basic research to clinical practice. Advances in Experimental Medicine and Biology(), vol 956. Springer, Cham. https://doi.org/10.1007/5584_2016_82

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  • DOI: https://doi.org/10.1007/5584_2016_82

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-44250-1

  • Online ISBN: 978-3-319-44251-8

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