Abstract
The aim of this study was to determine the level of anti-hemagglutinin antibodies in the serum of people in different age-groups during the 2014/2015 epidemic influenza season in Poland. A total of 1050 sera were tested. The level of anti-hemagglutinin antibodies was determined using the hemagglutinin inhibition test. The results provided information on the incidence of circulating A/California/7/2009(H1N1)pdm09, A/Texas/50/2012(H3N2), and B/Massachusetts/2/2012 viruses. The level of antibodies against influenza differed between age-groups. The protection rate was the highest for the antigen B/Massachusetts/2/2012, with the decreasing order of values in the following age-groups: ≥65 years (76.7 %), 15–25 years (72.7 %), and 0–4 years (62.0 %). The average values of the protection rate in other age-groups were as follows: 43.3 % in 22–64 years, 40% in 5–9 years, and 39.3 % in 45–64 years of age, while the lowest value of 22.7 % was in 10–14 years old subjects. In the 2014/2015 epidemic season in Poland only were 3.6 % of the population vaccinated. That is why the presented results could be interpreted as a response of the immune system of patients after infection caused by influenza virus.
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Acknowledgments
This work was funded by NIPH-NIH thematic subject 5/EM.1. Authors would like to acknowledge physicians and employees of Voivodeship Sanitary Epidemiological Stations participating in collecting sera and preparing epidemiological data.
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The authors declare no conflicts of interest in relation to this article.
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Kowalczyk, D., Szymański, K., Cieślak, K., Brydak, L.B. (2017). Circulation of Antibodies Against Influenza Virus Hemagglutinins in the 2014/2015 Epidemic Season in Poland. In: Pokorski, M. (eds) Influenza and Respiratory Care. Advances in Experimental Medicine and Biology(), vol 968. Springer, Cham. https://doi.org/10.1007/5584_2016_191
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DOI: https://doi.org/10.1007/5584_2016_191
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