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Size- and Ligand-Specific Bioresponse of Gold Clusters and Nanoparticles: Challenges and Perspectives

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Gold Clusters, Colloids and Nanoparticles I

Part of the book series: Structure and Bonding ((STRUCTURE,volume 161))

Abstract

This review gives an introduction to the chemical and physical properties of gold clusters and nanoparticles (NPs) and reflects the present understanding how such particles interact with biological systems in vitro and in vivo. It will acquaint the reader with the basic principles of interaction from a chemical point of view and illustrates perspectives that arise for the application of gold nanoparticles (AuNPs) in biological environments.

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Notes

  1. 1.

    The difference between the expression “cluster” and “nanoparticle” is not sharp. In the following we will use “cluster” for particles of a discrete number of atoms, whereas “nanoparticle” is used for less exactly defined species, allowing a certain size distribution.

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Authors and Affiliations

  1. Institute of Inorganic Chemistry, RWTH Aachen University, 52074, Aachen, Germany

    Janine Broda & Ulrich Simon

  2. Institute of Inorganic Chemistry, University Duisburg-Essen, 45127, Essen, Germany

    Günter Schmid

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  1. Inorganic Chemistry Laboratory, University of Oxford, Oxford, United Kingdom

    D. Michael P. Mingos

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Broda, J., Schmid, G., Simon, U. (2013). Size- and Ligand-Specific Bioresponse of Gold Clusters and Nanoparticles: Challenges and Perspectives. In: Mingos, D. (eds) Gold Clusters, Colloids and Nanoparticles I. Structure and Bonding, vol 161. Springer, Cham. https://doi.org/10.1007/430_2013_127

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