Skip to main content

Epidemiology of Pulmonary Embolism in Japan

  • Conference paper
Venous Thromboembolism

Conclusions

The incidence of PE is low in Japan compared with Western countries, but it has been increasing in recent years. The reasons for the low incidence may be genetic predisposition, lifestyle, and diagnostic power. On the other hand, the recent increment in incidence may result from changes in lifestyle and improvement in the diagnostic power.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Statistics and Information Department. Patient survey 1999, vol 1. Minister’s Secretariat, Ministry of Health, Labor and Welfare, Tokyo, 2001.

    Google Scholar 

  2. Statistics and Information Department. Vital statistics of Japan 1999, vol 3. Minister’s Secretariat, Ministry of Health, Labor and Welfare, Tokyo, 2001.

    Google Scholar 

  3. Sakuma M, Takahashi T, Kitamukai O, et al. Mortality from pulmonary embolism in Japan (in Japanese). J Jpn Coll Angiol 2001;41:2001.

    Google Scholar 

  4. Sakuma M, Konno Y, Shirato K. Increasing mortality from pulmonary embolism in Japan, 1951–2000. Circ J 2002;66:1144–9.

    PubMed  Google Scholar 

  5. Lilienfeld DE. Decreasing mortality from pulmonary embolism in the United States, 1979–1996. Int J Epidemiol 2000;29:465–9.

    Article  CAS  PubMed  Google Scholar 

  6. Hasegawa H, Nagata H, Yamauchi M, et al. Statistical status of pulmonary embolism in Japan (II). Jpn J Chest Dis 1981;40:677–81 (in Japanese).

    Google Scholar 

  7. Mieno T, Kitamura S. Incidence of pulmonary thromboembolism in Japan. Kokyu To Junkan 1989;37:923–7 (in Japanese).

    CAS  PubMed  Google Scholar 

  8. Sakuma M, Takahashi T, Kitamukai O, et al. Incidence of pulmonary embolism in Japan: analysis using “Annual of the pathological autopsy cases in Japan”. Ther Res 2002;23:632–4 (in Japanese).

    Google Scholar 

  9. Thomas WA, Davies JNP, O’Neal RM, et al. Incidence of myocardial infarction correlated with venous and pulmonary thrombosis and embolism: a geographic study based on autopsies in Uganda, East Africa and St. Louis, USA. Am J Cardiol 1960;5:41–7.

    CAS  PubMed  Google Scholar 

  10. Gore I, Hirst AE, Tanaka K. Myocardial infarction and thromboembolism. Arch Intern Med 1964;113:323–30.

    CAS  PubMed  Google Scholar 

  11. Elegbeleye OO, Femi-Pearse D. Pulmonary embolism in Africans. Trop Geogr Med 1975;27:31–3.

    CAS  PubMed  Google Scholar 

  12. Datta BN, Ramesh K, Bhusnurmath B. Autopsy incidence of pulmonary vascular episode: a study of 218 cases. Angiology 1986;37:744–50.

    CAS  PubMed  Google Scholar 

  13. Chau KY, Yuen ST, Ng THK, et al. An autopsy study of pulmonary thromboembolism in Hong Kong Chinese. Pathology 1991;23:181–4.

    CAS  PubMed  Google Scholar 

  14. Awotedu AA, Igbokwe EO, Akang EE, et al. Pulmonary embolism in Ibadan, Nigeria: five years autopsy report. Cent Afr J Med 1992;38:432–5.

    CAS  PubMed  Google Scholar 

  15. Chau KY, Yuen ST, Wong MP. seasonal variation in the necropsy incidence of pulmonary thromboembolism in Hong Kong. J Clin Pathol 1995;48:578–9.

    CAS  PubMed  Google Scholar 

  16. Nakano T, Ito S, Takezawa H. Epidemiology of pulmonary embolism. Jpn Med J 1980;2949:43–7 (in Japanese).

    Google Scholar 

  17. Matsubara O, Sato T, Kitagawa M, et al. Pulmonary thromboembolism: frequency, site, and vascular change in 103 autopsy cases. Am J Cardiovasc Pathol 1989;2:312–28.

    Google Scholar 

  18. Ito M. Pathology of pulmonary embolism. Kokyu To Junkan 1991;39;567–72 (in Japanese).

    CAS  PubMed  Google Scholar 

  19. Nakamura Y, Yutani C, Imaike M, et al. Pathophysiology of clinicopathological aspect of venous thrombosis and pulmonary thromboembolism. Jpn J Phlebol 1996;7:17–22 (in Japanese).

    Google Scholar 

  20. Murai T. Sudden death due to pulmonary thromboembolism. In: Annual report of the study project of sudden death supported by a Japanese Ministry of Health and Welfare Research Grant 1993, 140–142 (in Japanese).

    Google Scholar 

  21. Tanifuji T, Kageyama N, Ro A, et al. A histo-pathological study of fatal pulmonary embolism and deep vein thrombosis: in the study of deep vein thrombosis among forty patients with pulmonary thromboembolism. Jpn J Phlebol 2003;14:189–95 (in Japanese).

    Google Scholar 

  22. Kumasaka N, Sakuma M, Shirato K. Incidence of pulmonary thromboembolism in Japan. Jpn Circ J 1999;63:439–41.

    Article  CAS  PubMed  Google Scholar 

  23. Kitamukai O, Sakuma M, Takahashi T, et al. Incidence and characteristics of pulmonary thromboembolism in Japan 2000. Intern Med 2003;42:1090–4.

    PubMed  Google Scholar 

  24. Statistics and Information Department. Patient survey 1996, Volume I. Tokyo, 1998.

    Google Scholar 

  25. Statistics and Information Department. Patient survey 1993, vol I. Minister’s Secretariat, Ministry of Health and Welfare, Tokyo, 1995.

    Google Scholar 

  26. The Japanese Society of Pulmonary Embolism Research. Unpublished data.

    Google Scholar 

  27. Silverstein MD, Heit JA, Mohr DN, et al. Trends in the incidence of deep vein thrombosis and pulmonary embolism: a 25-year population-based study. Arch Intern Med 1998;158:585–93.

    Article  CAS  PubMed  Google Scholar 

  28. Klatsky AL, Armstrong MA, Poggi J. Risk of pulmonary embolism and/or deep venous thrombosis in Asian-Americans. Am J Cardiol 2000;85:1334–7.

    Article  CAS  PubMed  Google Scholar 

  29. Sakuma M, Nakamura M, Nakanishi N, et al. The results of the third registry of pulmonary thromboembolism: results of multicenter registry in the Japanese Society of Pulmonary Embolism Research. Ther Res 2004;25:1134–5 (in Japanese).

    Google Scholar 

  30. Okada O, Tanebe N, Yasuda J, et al. Comprehensive study for genetic factors in chronic thromboembolic pulmonary hypertension. In: Annual report of the study project of respiratory failure research committee supported by a Japanese Ministry of Health and Welfare Research Grant 1997. K Planning 1998:140–2 (in Japanese).

    Google Scholar 

  31. Kumasaka N, Sakuma M, Shirato K. Clinical features and predictors of in-hospital mortality in patients with acute and chronic pulmonary thromboembolism. Intern Med 2000;39:1038–43.

    CAS  PubMed  Google Scholar 

  32. Nakamura M, Fujioka H, Yamada N, et al. Clinical characteristics of acute pulmonary thromboembolism in Japan: results of multicenter registry in the Japanese Society of Pulmonary Embolism Research. Clin Cardiol 2001;24:132–238.

    CAS  PubMed  Google Scholar 

  33. Ridker PM, Hennekens CH, Lindpaintner K, et al. Mutation in the gene coding for coagulation factor V and the risk of myocardial infarction, stroke, and venous thrombosis in apparently healthy men. N Engl J Med 1995;332:912–5.

    Article  CAS  PubMed  Google Scholar 

  34. Rees DC, Cox M, Clegg JB. World distribution of factor V Leiden. Lancet 1995;346:1133–4.

    CAS  PubMed  Google Scholar 

  35. Poort SR, Rosendaal FR, Reitsma PH, et al. A common genetic variation in the 3’-untranslated region of the prothorombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 1996;88:3698–703.

    CAS  PubMed  Google Scholar 

  36. Tosetto A, Missiaglia E, Frezzato M, et al. The VITA project: prothrombin G20210A mutation and venous thromboembolism in the general population. Thromb Haemostasis 1999;82:1395–8.

    CAS  Google Scholar 

  37. Seki T, Okayama H, Kumagai T, et al. Arg506Gln mutation of the coagulation factor V gene not detected in Japanese pulmonary thromboembolism. Heart Vessels 1998; 13:195–8.

    Article  CAS  PubMed  Google Scholar 

  38. Miyata T, Kawasaki T, Fujimura H, et al. The prothrombin gene G20210A mutation is not found among Japanese patients with deep vein thrombosis and healthy individuals. Blood Coagul Fibrinolysis 1998;9:451–2.

    CAS  PubMed  Google Scholar 

  39. The study circle for health and nutrition information. The national nutrition survey in Japan, 2001: Ministry of Health, Labor and Welfare, Japan. Diaachi Shuppan, Tokyo, 2003 (in Japanese).

    Google Scholar 

  40. Yoshiike N, Matsumura Y, Zaman MM, et al. Descriptive epidemiology of body mass index in Japanese adults in a representative sample from the National Nutrition Survey 1990–1994. Int J Obes 1998;22:684–7.

    Article  CAS  Google Scholar 

  41. Tanaka H, Kokubo Y. Epidemiology of obesity. J Jpn Med Assoc 2003;130:25–30 (in Japanese).

    Google Scholar 

  42. WHO. Obesity: preventing and managing the global epidemic. Report of a WHO consultation. WHO technical report series, no 894. World Health Organization, Geneva, 2000.

    Google Scholar 

  43. Sakuma M, Takahashi T, Kitamukai O, et al. Autopsy incidence of pulmonary thromboembolism. Ther Res 2002;23:632–4 (in Japanese).

    Google Scholar 

  44. Sakuma M, Okada O, Nakamura M, et al. Recent developments in diagnostic imaging techniques and management for acute pulmonary embolism: multicenter registry by the Japanese Society of pulmonary Embolism research. Intern Med 2003;42:470–6.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Springer-Verlag Tokyo

About this paper

Cite this paper

Sakuma, M. et al. (2005). Epidemiology of Pulmonary Embolism in Japan. In: Shirato, K. (eds) Venous Thromboembolism. Springer, Tokyo. https://doi.org/10.1007/4-431-27121-X_1

Download citation

  • DOI: https://doi.org/10.1007/4-431-27121-X_1

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-22080-0

  • Online ISBN: 978-4-431-27121-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics