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Assessment and treatment of sleep disturbances in aged population

  • Tejas R. Shah
  • Nikola N. Trajanovic
  • Colin M. Shapiro

Keywords

Obstructive Sleep Apnea Continuous Positive Airway Pressure Sleep Disorder Sleep Disorder Breathing Total Sleep Time 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Feinsilver S (2003) Sleep in the elderly what is normal? Clin Geriatr Med 19: 177–188PubMedCrossRefGoogle Scholar
  2. 2.
    Fleming J, Shapiro CM, Flanigan M, Hanly P, Kryger M, Levitt A, Abbey S, Broughton R, Czeisler C (1995) Kommunicom publications, volume 1: Sleep function and insomnia assessment: 2–32 and volume 2 insomnia management: 34–49Google Scholar
  3. 3.
    Shapiro CM (1974) A third state of existence. Leech 44: 13–16Google Scholar
  4. 4.
    Martin J, Shochat T, Ancoli-Israel S (2000) Assessment and treatment of sleep disturbances in older adults. Clin Psychol Rev 20: 783–805PubMedCrossRefGoogle Scholar
  5. 5.
    Schneider D (2002) Safe and effective therapy for sleep problems in the older patient. Geriatrics 57: 24–35PubMedGoogle Scholar
  6. 6.
    Shaver J, Giblin E, Lentz M, Lee K (1988) Sleep patterns and stability in perimenopausal women. Sleep 11: 556–561PubMedGoogle Scholar
  7. 7.
    Ledesert B, Ringa V, Breart G (1995) Menopause and perceived health status among the women of the French GAZEL cohort. Maturitas 20: 113–120CrossRefGoogle Scholar
  8. 8.
    Moe KE (2004) Hot flashes and sleep in women. Sleep Med Rev 8: 487–497PubMedCrossRefGoogle Scholar
  9. 9.
    Polo-Kantola P, Erkkola R (2004) Sleep and the menopause. J Br Menopause Soc 10: 145–150PubMedCrossRefGoogle Scholar
  10. 10.
    Barrett-Connor E, Grady D, Stefanick ML(2005) The rise and fall of menopausal hormone therapy. Annu Rev Public Health 26: 115–140PubMedCrossRefGoogle Scholar
  11. 11.
    Cohen O, Vinker S, Yaphe J, Kitai E (2005) Hormone replacement therapy and WONCA/COOP functional status: a cross-sectional population-based study of women in Israel. Climacteric 8: 171–176PubMedCrossRefGoogle Scholar
  12. 12.
    Gambacciani M, Ciaponi M, Cappagli B, Monteleone P, Benussi C, Bevilacqua G, Vacca F, Genazzani AR (2005) Effects of low-dose, continuous combined hormone replacement therapy on sleep in symptomatic postmenopausal women. Maturitas 50: 91–97PubMedCrossRefGoogle Scholar
  13. 13.
    Ohayon M, Carskadon M, Guilleminault C, Vitiello M (2004) Meta-Analysis of quantitative sleep parameters from childhood to old age in healthy individuals: developing normative sleep values across the human lifespan. Sleep 27: 1255–1273PubMedGoogle Scholar
  14. 14.
    Swift CG, Shapiro CM (1993) ABC of sleep disorders. Sleep and sleep problems in elderly people. Brit Med J 306: 1468–1471PubMedGoogle Scholar
  15. 15.
    Shin K, Shapiro CM (2003) Menopause, sex hormones, and sleep. Bipolar Disord 5: 106–109, reviewPubMedCrossRefGoogle Scholar
  16. 16.
    Tamaki M, Shirota AI, Tanaka H, Hayashi M, Hori T (1999) Effects of a daytime nap in the aged. Psychiatry Clin Neurosci 53: 273–275PubMedCrossRefGoogle Scholar
  17. 17.
    Shapiro G, Shen J, Shapiro CM (2004) Sleep changes in the depressed older adults: Implications for management. Geriatrics and Aging 7: 25–31Google Scholar
  18. 18.
    Sloan E, Flint A, Reinish L, Shapiro CM (1996) Circadian rhythms and psychiatric disorders in the elderly. J Geriatr Psychiatry Neurol 9: 164–170PubMedGoogle Scholar
  19. 19.
    Ancoli-Israel S, Steven Poceta J, Stepnowsky C, Martin J, Gehrman P (1997) Identification and treatment of sleep problems in the elderly. Sleep Med Rev 1: 3–17PubMedCrossRefGoogle Scholar
  20. 20.
    Ancoli-Israel S (1997) Sleep problems in older adults: Putting myths to bed. Geriatrics 52: 20–30PubMedGoogle Scholar
  21. 21.
    Chilcott LA, Shapiro CM (1996) The socioeconomic impact of insomnia: An overview. Pharmaco Economics 10,Suppl. 1: 1–14Google Scholar
  22. 22.
    Vitiello M (1999) Effective treatments for age-related sleep disturbances. Geriatrics 54: 47–52PubMedGoogle Scholar
  23. 23.
    Kayumov L, Brown G, Jindal R, Buttoo K, Shapiro CM (2001) A randomized, double blind, placebo-controlled crossover study of the effect of exogenous melatonin on delayed sleep phase syndrome. Psychosom Med 63: 40–48PubMedGoogle Scholar
  24. 24.
    Martins Jr E, Oliveira AP, Araujo AM, Lima W, Cipollaneto J, Costa Rosa L (2001) Melatonin modulate allergic lung inflammation. J Pineal Res 31: 363–369PubMedCrossRefGoogle Scholar
  25. 25.
    Sutherland ER, Ellison MC, Kraft M, Martin RJ (2003) Elevated serum melatonin is associated with the nocturnal worsening of asthma. J Allergy Clin Immunology 112: 513–517CrossRefGoogle Scholar
  26. 26.
    Weekly LB (1993) Effects of melatonin on pulmonary and coronary vessels are exerted through perivascular nerves. Clin Auton Res 3: 45–47CrossRefGoogle Scholar
  27. 27.
    Flamer H (1996) Sleep disorders in the elderly. Aust NZ J Medicine 26: 96–104Google Scholar
  28. 28.
    Young T, Palten M, Denpsey J, Shatrud J, Weber S, Badr S (1993) The occurrence of sleep disordered breathing among middle aged adults. New Engl J Med 328: 1230–1235PubMedCrossRefGoogle Scholar
  29. 29.
    Schröder CM, O’Hara R (2005) Depression and obstructive sleep apnea (OSA). Annals of Gen Psychiatry 4: 13CrossRefGoogle Scholar
  30. 30.
    Ancoli-Israel S, Klauber MR, Stepnowsky C, Estline E, Chinn A, Fell R (1995) Sleep-disordered breathing in African-American elderly. Am J Respri Crit Care Med 152: 1946–1949Google Scholar
  31. 31.
    Barthlen G (2002) Sleep disorders — Obstructive sleep apnea syndrome, restless legs syndrome, and insomnia in geriatric patients. Geriatrics 57: 34–39PubMedGoogle Scholar
  32. 32.
    Aloia M, Arnedt J, Davis J, Riggs R, Byrd D (2004) Neuropsychological sequeale of obstructive sleep apnea-hypopnea syndrome: A critical review. J Int Neuropsychol Soc 10: 772–785PubMedCrossRefGoogle Scholar
  33. 33.
    Carley DW, Radulovacki M (1999) Mirtazapine, a mixed-profile serotonin agonist/antagonist, suppresses sleep apnea in the rat. Am J Respir Crit Care Med 160: 1824–1829PubMedGoogle Scholar
  34. 34.
    Castillo JL, Menendez P, Segovia C, Guilleminault C (2004) Effectiveness of mirtazapine in the treatment of sleep apnea/hypopnea syndrome (SAHS). Sleep Med 5: 507–508PubMedCrossRefGoogle Scholar
  35. 35.
    Smith PL, Haponik EF, Bleecker ER (1984) The effects of oxygen in patients with sleep apnea. Am Rev Respir Dis 130: 958–963PubMedGoogle Scholar
  36. 36.
    Gold AR, Bleecker ER, Smith PL (1985) A shift from central and mixed sleep apnea to obstructive sleep apnea resulting from low-flow oxygen. Am Rev Respir Dis 132: 220–223PubMedGoogle Scholar
  37. 37.
    Fletcher EC, Munafo DA (1990) Role of nocturnal oxygen therapy in obstructive sleep apnoea. Chest 98: 1497–1505PubMedGoogle Scholar
  38. 38.
    DeBacker WA, Verbraecken J, Willemen M, Wittesaele W, DeCock W, Van deHeyning V (1995) Central apnea index decreases after prolonged treatment with acetazolamide. Am J Respir Crit Care Med 151: 87–91PubMedGoogle Scholar
  39. 39.
    Javaheri S (2005) Central sleep apnea in congestive heart failure: prevalence, mechanisms, impact, and therapeutic options. Semin Respir Crit Care Med 26: 44–55PubMedCrossRefGoogle Scholar
  40. 40.
    Benca R (2005) Diagnosis and treatment of chronic insomnia: A review. Psychiatr Serv 56: 332–343PubMedCrossRefGoogle Scholar
  41. 41.
    Foley DJ, Monjan AA, Brown SL, Simonsick EM, Wallace RB, Blazer DG (1995) Sleep complaints among elderly persons: An epidemiologic study of the three communitries. Sleep 18: 425–432PubMedGoogle Scholar
  42. 42.
    Shapiro CM, Morris A (2004) Insomnia in older adults, Part I: Assessment geriatrics and aging 7(7) and 7 (9): 3–8Google Scholar
  43. 43.
    McCall W (2004) Sleep in the elderly: Burden, diagnosis, and treatment. Prim Care Companion J Clin Psychiatry 6: 9–20PubMedGoogle Scholar
  44. 44.
    Shapiro CM, Steingart A (1993) Fifty-one questions for the elderly insomniacs and why. Sleep disorders and insomnia in the elderly. Facts and Research in Gerontology 7: 223–232Google Scholar
  45. 45.
    Bachman D (1992) Sleep disorders with aging: Evaluation and treatment. Geriatrics 47:53–61PubMedGoogle Scholar
  46. 46.
    Morris A, Moller H, Shapiro CM (2004) Insomnia in older adults, Part II: Treatment. Geriatrics and aging 7: 9–14Google Scholar
  47. 47.
    Sloan E, Hauri P, Bootzin R, Morin C, Stevenson M, Shapiro CM (1993) The nuts and bolts of behavioral therapy for insomnia. J Psychosom Res 37: 19–37PubMedCrossRefGoogle Scholar
  48. 48.
    Greenblatt DJ, Shader RI, Harmatz JS (1989) Implications of altered drug disposition in the elderly: studies of benzodiazepines. J Clin Pharmacol 29: 866–872PubMedGoogle Scholar
  49. 49.
    Cumming RG, Le Couteur DG (2003) Benzodiazepines and risk of hip fractures in older people: a review of the evidence. CNS Drugs 17: 825–837PubMedCrossRefGoogle Scholar
  50. 50.
    Vermeeren J (2004) Residual effects of hypnotics: epidemiology and clinical implications. CNS Drugs 18: 297–328PubMedCrossRefGoogle Scholar
  51. 51.
    Schenweiss S, Wang PS (2005) Claims data studies of sedative-hypnotics and hip fractures in older people: exploring residual confounding using survey information. J Am Geriatr Soc 53: 948–954CrossRefGoogle Scholar
  52. 52.
    Avidan AY, Fries BE, James ML, Szafara KL, Wright GT, Chervin RD (2005) Insomnia and hypnotic use, recorded in the minimum data set, as predictors of falls and hip fractures in Michigan nursing homes. J Am Geriatr Soc 53: 955–962PubMedCrossRefGoogle Scholar
  53. 53.
    Barbera J, Shapiro CM (2005) Benefit-risk assessment of zaleplon in the treatment of insomnia. Drug Saf 28: 301–318PubMedCrossRefGoogle Scholar
  54. 54.
    Ancoli-Israel S (2000) Insomnia in the elderly: a review for the primary care practitioner. Sleep 23: S23–S30, discussion S36–S38PubMedGoogle Scholar
  55. 55.
    Allain H, Bentue-Ferre D, Tarral A, Gandon JM (2004) Effects on postural oscillation and memory functions of a single dose of zolpidem 5 mg, zopiclone 3.75mgand lormetazepam 1 mg in elderly healthy subjects. A randomized, cross-over, double-blind study versus placebo. Eur J Clin Pharmacol 59: 179–188Google Scholar
  56. 56.
    Linjakumpu TA, Hartikainen SA, Klaukka TJ, Koponen HJ, Hakko HH, Viilo KM, Haapea M, Kivela SL, Isoaho RE (2004) Sedative drug use in the home-dwelling elderly. Ann Pharmacother 38: 2017–2022PubMedCrossRefGoogle Scholar
  57. 57.
    Kopanski Z, Sliwinska M, Piekoszewski W, Habiniak J, Wojewoda T, Wojewoda A, Schlegel-Zawadzka M, Sibiga W (2001) Endogenous diazepam concentrations in the serum of patients with liver neoplasms. Folia Histochem Cytobiol 39: 124–126PubMedGoogle Scholar
  58. 58.
    Gaillot J, Le Roux Y, Houghton GW, Dreyfus JF (1987) Critical factors for pharmacokinetics of zopiclone in the elderly and in patients with liver and renal insufficiency. Sleep 10: 7–21PubMedGoogle Scholar
  59. 59.
    Brodeur MR, Stirling AL (2001) Delirium associated with zolpidem. Ann Pharmacother 35: 1562–1564PubMedCrossRefGoogle Scholar
  60. 60.
    Greenblatt DJ, Harmatz JS, Shapiro L, Engelhardt N, Gouthro TA, Shader RI (1991) Sensitivity to triazolam in elderly. New Engl J Med 324: 1691–1698PubMedCrossRefGoogle Scholar
  61. 61.
    Koda-Kimble MA, Young LY, Kradjan WA, Guglielmo B, Alldredge BK, Corelli RL (2004) Applied therapeutics: The clinical use of drugs, 8th edition. Lippincott Williams and Wilkins, Baltimore, 77.1–77.20Google Scholar
  62. 62.
    Glass JR, Sproule BA, Herrmann N, Streiner D, Busto UE (2003) Acute pharmacological effects of temazepam, diphenhydramine, and valerian in healthy elderly subjects. J Clin Psychopharmacol 23: 260–268PubMedCrossRefGoogle Scholar
  63. 63.
    Antilla SA, Leinonen EV (2001) A review of the pharmacological and clinical profile of mirtazapine. CNS Drug Rev 7: 249–264CrossRefGoogle Scholar
  64. 64.
    Wingen M, Bothemer J, Langer S, Ramaekers JG (2005) Actual driving performance and psychomotor function in healthy subjects after acute and subchronic treatment with escitalopram, mirtazapine, and placebo: a crossover trial. J Clin Psychiatry 66: 436–443PubMedGoogle Scholar
  65. 65.
    Ridout F, Meadows R, Johnsen S, Hindmarch I (2003) A placebo controlled investigation into the effects of paroxetine and mirtazapine on measures related to car driving performance. Hum Psychopharmacol 18: 261–269PubMedCrossRefGoogle Scholar
  66. 66.
    Onofrj M, Luciano AL, Thomas A, Jacono D, D’Andreamatteo G (2003) Mirtazapine induces REM sleep behavior disorder (RBD) in Parkinsonism. Neurology 60: 113–115PubMedCrossRefGoogle Scholar
  67. 67.
    Mendelson WB (2005) A review of the evidence for the efficacy and safety of trazodone in insomnia. J Clin Psychiatry 66: 469–476PubMedCrossRefGoogle Scholar
  68. 68.
    Kaynak H, Kaynak D, Gozukirmizi F, Guilleminault C (2004) The effects of trazodone on sleep in patients treated with stimulant antidepressants. Sleep Med 5: 15–20PubMedCrossRefGoogle Scholar
  69. 69.
    Johnson EO, Roehrs T, Roth T, Breslau N (1998) Epidemiology of alcohol and medication as aids to sleep in early adulthood. Sleep 21: 178–186PubMedGoogle Scholar
  70. 70.
    Neubauer DN (1999) Sleep problems in the elderly. Am Fam Physician 59: 2551–2558PubMedGoogle Scholar
  71. 71.
    Trendwalder C, Hundemer H-P, Lledo A, Swieca J, Polo O, Wetter TC, Ferini-Strambi L, Groen H, Quail D, Brandenburg U (2004) The PEARLS study-Efficacy of pergolide in treatment of restless legs syndrome. Neurology 62: 1391–1397Google Scholar
  72. 72.
    Happe S, Klosch G, Saletu B, Zeitlhofer J (2001) Treatment of idiopathic restless legs syndrome with gabapentin. Neurology 57: 1717–1719PubMedGoogle Scholar
  73. 73.
    Lavigne GJ, Montplaisir JY (1994) Restless legs syndrome and sleep bruxism: prevalence and association among Canadians. Sleep 17: 739–743PubMedGoogle Scholar
  74. 74.
    Hornyak M, Trenkwalder C (2004) Restless legs syndrome and periodic limb movement disorder in the elderly. J Psychosom Res 56: 543–548PubMedCrossRefGoogle Scholar
  75. 75.
    Chaudhri KR, Appiah-kubi LS, Trenkwalder C (2001) Restless legs syndrome. J Neurol Neurosurg Psychiatry 71: 143–146CrossRefGoogle Scholar
  76. 76.
    Chokroverty S (2003) Editor’s corner: restless legs syndrome, a common disease uncommonly diagnosed. Sleep Medicine 4: 91–93PubMedCrossRefGoogle Scholar
  77. 77.
    Trenkwalder C, Paulus W, Walters A (2005) The restless legs syndrome. Lancet Neurology 4: 465–475PubMedCrossRefGoogle Scholar
  78. 78.
    Walters AS, Winklemann J, Trenkwalder C, Fry JM, Kataria V, Wagner M, Sharma R, Hening W, Li L (2001) Long-term follow up on restless legs syndrome patients treated with opioids. Movement disorders 16: 1105–1109PubMedCrossRefGoogle Scholar
  79. 79.
    Grewal M, Hawa R, Shapiro CM (2002) Treatment of periodic limb movements in sleep with selegiline HCL. Movement disorders 17: 398–401PubMedCrossRefGoogle Scholar
  80. 80.
    Shapiro CM, Ohayon M, Huterer N, Grunstein R (2005) Fighting fatigue and sleepiness. Practical strategies for minimizing sleepiness and fatigue. Joli joco publications Inc., OntarioGoogle Scholar
  81. 81.
    Shapiro CM, Dement WC (1993) ABC of sleep disorders. Impact and epidemiology of sleep disorders. BMJ 306: 1604–1607PubMedGoogle Scholar
  82. 82.
    Shapiro CM, Devins GM, Hussain MR (1993) ABC of sleep disorders. Sleep problems in patients with medical illness. BMJ 306: 1532–1535PubMedCrossRefGoogle Scholar

Copyright information

© Birkhäuser Verlag/Switzerland 2006

Authors and Affiliations

  • Tejas R. Shah
    • 1
  • Nikola N. Trajanovic
    • 1
  • Colin M. Shapiro
    • 2
  1. 1.Sleep and Alertness ClinicMed West Medical CentreTorontoCanada
  2. 2.Sleep Research UnitToronto Western HospitalTorontoCanada

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