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Chapter 17
Maizels, N. 1995. Somatic hypermutation: how many mechanisms diversify V region sequences? Cell. 83:9.
Wagner, S.D., Neuberger, M.S. 1996. Somatic hypermutation of immunoglobulin genes. Annu. Rev. Immunol. 14:441.
Muramatsu, M., Kinoshita, K., Fagarasan, S., Yamada, S., Shinkai, Y., Honjo, T. 2000. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 102:553.
Petersen-Mahrt, S.K., Harris, R.S., Neuberger, M.S. 2002. AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification. Nature 418:99.
Kinoshita, K., Honjo, T. 2001. Linking class-switch recombination with somatic hypermutation. Nat. Rev. Mol. Cell Biol. 2:493.
Honjo, T., Muramatsu, M., Fagarasan, S. 2004. AID: how does it aid antibody diversity? Immunity 20:659.
Neuberger, M.S., Harris, R.S., Di Noia, J., Petersen-Mahrt, S.K. 2003. Immunity through DNA deamination. Trends Biochem. Sci. 28:305.
Neuberger, M.S., Di Noia, J.M., Beale, R.C., Williams, G.T., Yang, Z., Rada, C. 2005. Somatic hypermutation at A.T pairs: polymerase error versus dUTP incorporation. Nat. Rev. Immunol. 5:171.
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(2005). The antibody problem today — not quite solved. In: Köhler’s Invention. Birkhäuser Basel. https://doi.org/10.1007/3-7643-7413-6_17
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DOI: https://doi.org/10.1007/3-7643-7413-6_17
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