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Enzymatically Controlled Reactions of Organofluorine Compounds

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Organofluorine Chemistry

Part of the book series: Topics in Current Chemistry ((TOPCURRCHEM,volume 193))

Abstract

The biotransformation of organofluorine materials into optically active functionalized fluorinated materials along with a discussion on the effect of fluorine atom(s) during enantioselective and/or diastereoselective transformations is described. The ability of microorganisms to discriminate between enantiomers is particularly important regarding resolution and asymmetric synthesis. Furthermore, the use of chiral fluorinated materials in the design and preparation of new types of biologically active materials is discussed.

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Authors and Affiliations

  1. Department of Bioengineering, Tokyo Institute of Technology, Nagatsuta, Midori-ku, Yokohama, 226, Japan

    T. Kitazume & T. Yamazaki

Authors
  1. T. Kitazume
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  2. T. Yamazaki
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Editors and Affiliations

  1. Department of Chemistry, University of Durham, South Road, Durham, DH1 3LE, Great Britain

    Richard D. Chambers F. R. S.

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© 1997 Springer Verlag Berlin Heidelberg

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Kitazume, T., Yamazaki, T. (1997). Enzymatically Controlled Reactions of Organofluorine Compounds. In: Chambers, R.D. (eds) Organofluorine Chemistry. Topics in Current Chemistry, vol 193. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-69197-9_3

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  • DOI: https://doi.org/10.1007/3-540-69197-9_3

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  • Print ISBN: 978-3-540-63170-5

  • Online ISBN: 978-3-540-69197-6

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