Noninvasive skin imaging
An earlier model of colour formation within normal human skin was extended to include architectural distortions associated with various pigmented skin lesions, including malignant melanoma. The extended five-layer model makes it possible to derive parameters characterising the thickness and pigment composition of the skin layers from calibrated colour and infrared images of skin lesions. The extracted parameters can be used to reconstruct a full 3-dimensional model of the skin architecture which conveys information grossly comparable to that available through microscopical examination of biopsied skin tissue.
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