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Post-Systolic Thickening in Ischaemic Myocardium: A Simple Mathematical Model for Simulating Regional Deformation

  • Piet Claus
  • Bart Bijnens
  • Frank Weidemann
  • Christoph Dommke
  • Virginie Bito
  • Frank Heinzel
  • Karin Sipido
  • Ivan De Scheerder
  • Frank E. Rademakers
  • George R. Sutherland
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 2230)

Abstract

We present a one-dimensional mathematical model to explain changes in regional radial myocardial deformation during ischaemia. The model makes use of cellular contraction properties of normal and ischaemic myocytes extracted from an animal model of induced chronic, regional ischaemia of the posterior wall. Simulations of the model are compared to the deformation patterns observed in the experimental animal models of regional ischaemia.

Keywords

Total Occlusion Radial Strain Regional Ischaemia Maxwell Element Regional Myocardial Function 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer-Verlag Berlin Heidelberg 2001

Authors and Affiliations

  • Piet Claus
    • 1
  • Bart Bijnens
    • 1
  • Frank Weidemann
    • 1
  • Christoph Dommke
    • 1
  • Virginie Bito
    • 1
  • Frank Heinzel
    • 1
  • Karin Sipido
    • 1
  • Ivan De Scheerder
    • 1
  • Frank E. Rademakers
    • 1
  • George R. Sutherland
    • 1
  1. 1.Department of Cardiology, K.U. LeuvenUniversity Hospitals GasthuisbergLeuvenBelgium

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