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Aluminum: Interaction with Nucleotides and Nucleotidases and Analytical Aspects of Its Determination

  • Maria Rosa Chitolina Schetinger
  • Vera Maria Morsch
  • Denise Bohrer
Chapter
Part of the Structure and Bonding book series (STRUCTURE, volume 104)

Abstract

Aluminum is known to affect a wide variety of biological systems. The evolution of life in a highly aluminum-rich biosphere did not result in a known physiological role of aluminum, which is considered a non-essential trace element of low toxicity in living being. In this chapter we review some toxicological and biological aspects of aluminum, as well as the interaction of this element with enzymes that use nucleotides in their reactions. It is assumed that phosphate-bearing biomolecules are elected targets for the biochemical action for aluminum. There is a large number of proteins which require nucleoside phosphates as substrates or are regulated by them. The toxicological mechanisms of aluminum in plants or animals probably involve alterations in the activity of such proteins. As examples of enzymes focus will be placed on NTPases, NTPDases, and kinases. As aluminum in biological systems occurs at trace levels, the analysis of biological matrices will be outlined with respect to aluminum determination considering contamination sources, sample collection and preparation, and methodological procedures.

Keywords

Aluminum Nucleotide-binding Nucleotidases Contamination 

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References

  1. 1.
    Lévesque L, Mizzen CA, McLachlan R, Fraser PE (2000) Brain Res 877: 191CrossRefGoogle Scholar
  2. 2.
    Williams RJP (1999) J Inorg Chem 76: 81Google Scholar
  3. 3.
    Chadwick DJ, Whelan J (eds) (1992) Aluminum in Biology and Medicine, Ciba Foundation Symposium 169, Wiley, ChichesterGoogle Scholar
  4. 4.
    Williams RJP (1996) Coord Chem Rev 149: 1Google Scholar
  5. 5.
    Atwood DA, Yearwood BC (2000) J Org Chem 600: 186CrossRefGoogle Scholar
  6. 6.
    Whitehead MK, Farrar G, Christie GL, Blair JÁ, Thompson RPH (1997) Am J Clin Nutr 65: 1446Google Scholar
  7. 7.
    Berthon G (1996) Coord Chem Rev 149: 241Google Scholar
  8. 8.
    Corain B, Nicolini M, Zatta P (1992) Coord Chem Rev 112: 33CrossRefGoogle Scholar
  9. 9.
    Kiss T (1995) Arch Geront Ger 21: 99CrossRefGoogle Scholar
  10. 10.
    Yokel RA, Rhineheimer SS, Brauer RD, Sharma P, Elmore D, McNamara PJ (2001) Toxicol 161: 93CrossRefGoogle Scholar
  11. 11.
    Kochian LV (1995) Annu Rev Plant Physiol Plant Mol Biol 46: 237CrossRefGoogle Scholar
  12. 12.
    Pan JW, Zhu MY, Chen H (2001) Environ Exp Bot 46: 71CrossRefGoogle Scholar
  13. 13.
    Severi A (1997) Environ Exp Bot 37: 53CrossRefGoogle Scholar
  14. 14.
    Rai LC, Husaini Y, Mallick N (1998) Aquat Toxicol 42: 67CrossRefGoogle Scholar
  15. 15.
    Yokel RA, McNamara PJ (2001) Pharmacol Toxicol 88: 159CrossRefGoogle Scholar
  16. 16.
    Harris WR, Berthon G, Day JP, Exley C, Flaten TP, Forbes WF, Kiss T, Orvig C, Zatta PF (1996) J Toxicol And Environ Health 48: 543CrossRefGoogle Scholar
  17. 17.
    Kiss T, Zatta P, Corain B (1996) Coord Chem Rev 149: 329Google Scholar
  18. 18.
    Nelson DJ (1996) Coord Chem Rev 149: 95Google Scholar
  19. 19.
    Froment DPH, Molitoris BA, Buddington B, Miller N, Alfrey AC (1989) Kidney Int 36: 978CrossRefGoogle Scholar
  20. 20.
    Slanina P, Freeh, W, Eskon L, Loof L, Slovach S, Cedergen A (1986) Clin Chem 32: 539Google Scholar
  21. 21.
    Wang X, Nelson DJ, Trindle C, Martin RB (1997) J Inorg Biochem 59: 7CrossRefGoogle Scholar
  22. 22.
    Weiner ML, Salminen WF, Larson PR, Barter RA, Kranetz JL, Simon GS (2001) Food Chem Toxicol 39: 759CrossRefGoogle Scholar
  23. 23.
    Öhman LO, Martin RB (1994) Clin Chem 40: 598Google Scholar
  24. 24.
    Daydé S, Filíela M, Berthon G (1990) J Inorg Biochem 38: 241CrossRefGoogle Scholar
  25. 25.
    Dyrssen D, Haraldsson C, Nyberg E, Wedborg M (1987) J Inorg Biochem 29: 67CrossRefGoogle Scholar
  26. 26.
    Huang H, Liu M, Mao XA (1998) Spectrochim Acta Part A 54: 999CrossRefGoogle Scholar
  27. 27.
    Waldron-Edward D, Chan D, Skoryna SC (1971) Can Med Assoc J 105: 1297Google Scholar
  28. 28.
    Jackson GE, Voyi K (1987) Polyhedron 6: 2095CrossRefGoogle Scholar
  29. 29.
    Champmartin D, Rubini, P, Lakatos A, Kiss T (2001) J Inorg Biochem 84: 13CrossRefGoogle Scholar
  30. 30.
    Venturini-Soriano M, Berthon G (2001) J Inorg Biochem 85: 143CrossRefGoogle Scholar
  31. 31.
    Gandolfi L, Stella MP, Zambenedetti P, Zatta P (1998) Biochim Biophys Acta 1406: 315Google Scholar
  32. 32.
    Julka D, Gill K (1996) Biochim Biophys Acta 1315: 47Google Scholar
  33. 33.
    Wyse AT, Bavaresco CS, Bandinelli C, Streck EL, Franzon, R, Dutra-Filho CS, Wagner M (2001) Neurochem Res 26: 515CrossRefGoogle Scholar
  34. 34.
    Zatta P, Zambenedetti P, Pizziuti A, Perazzolo, M (1995) Neurosci Lett 197: 65CrossRefGoogle Scholar
  35. 35.
    Lai JCK, Guest JF, Leung TKC, Lim L, Davison, AN (1980) Biochem Pharmacol 29: 141CrossRefGoogle Scholar
  36. 36.
    Martin RB (1986) Clin Chem 32: 1797Google Scholar
  37. 37.
    Macdonald TL, Humpreys WG, Martin RB (1987) Science 236: 183CrossRefGoogle Scholar
  38. 38.
    Swegert CV, Dave KR, Katyare SS (1999) Mechanisms of Ageing and Development 112: 27CrossRefGoogle Scholar
  39. 39.
    Zatta P, Taylor A, Zambenedetti P, Milacic R, dell’Antone P (2000) Life Sci 66: 2261CrossRefGoogle Scholar
  40. 40.
    Jones DL, Kochian LV (1997) FEBS 400: 51CrossRefGoogle Scholar
  41. 41.
    Ma JF, Ryan PR, Delhaize, E (2001) Trends Plant Sci 6: 1385CrossRefGoogle Scholar
  42. 42.
    Hamilton CA, Good AG, Taylor GJ (2001) Plant Physiol 125: 2068CrossRefGoogle Scholar
  43. 43.
    Taylor GJ, Basu A, Basu U, Slaski JJ, Zhang G, Good A (1997) Plant Physiol 114: 363Google Scholar
  44. 44.
    Tu S-I, Brouilette JN (1987) Phytochemistry 26: 65CrossRefGoogle Scholar
  45. 45.
    Korchazhkina O, Wright G, Exley C (1999) J Inorg Biochem 76: 121CrossRefGoogle Scholar
  46. 46.
    Matzel LD, Rogers RF, Talk AC (1996) Neuroscience 74: 1175Google Scholar
  47. 47.
    Miller JL, Hubbard CM, Litman BJ, Macdonald TL (1989) J Biol Chem 264: 243Google Scholar
  48. 48.
    MacDonald TL, Martin RB (1988) TIBs 13: 15Google Scholar
  49. 49.
    Landino LM, Macdonald TL (1997) J Inorg Biochem 66: 99CrossRefGoogle Scholar
  50. 50.
    Chabre M (1989) Biochem J 258: 931Google Scholar
  51. 51.
    Coleman DE, Berghius AM, Lee E, Linder ME, Gilman AG, Sprang SR (1994) Science 265: 1405CrossRefGoogle Scholar
  52. 52.
    Shafer TJ, Mundy WR (1995) Gen Pharmacol 26:889Google Scholar
  53. 53.
    Fraser SP, Barrett P, Moon C, Morgan PJ, Djamgoz MBA (1994) Molec Neuropharmacol 3: 175Google Scholar
  54. 54.
    Moon C, Fraser SP, Djamboz MBA (1997) Cell Signal 9: 497CrossRefGoogle Scholar
  55. 55.
    Shafer TJ, Nostrandt AC, Tilson HÁ, Mundy WR (1994) Biochem Pharmac 47: 1417CrossRefGoogle Scholar
  56. 56.
    Li L, Fleming N (1999) FEBS 461: 1CrossRefGoogle Scholar
  57. 57.
    Nostrandt AC, Shafer TJ, Mundy WR, Padilla S (1994) The Toxicologist 14: 351Google Scholar
  58. 58.
    Zimmermann H, Braun N, Kegel B, Heine P (1998) Neurochem Int 32: 421CrossRefGoogle Scholar
  59. 59.
    Schetinger MRC, Wyse ATS, Da Silva LB, Barcellos CK, Dias RD, Sarkis JJF (1995) Biol Trace Elem Res 50: 209CrossRefGoogle Scholar
  60. 60.
    Burnstock G (1997) Neuropharmacol 36: 1127CrossRefGoogle Scholar
  61. 61.
    Exley C, Price NC, Birchall JD (1994) J Inorg Chem 54: 297Google Scholar
  62. 62.
    Stewart DC, Copeland L (1993) Phytochemistry 32: 27CrossRefGoogle Scholar
  63. 63.
    Cochran M, Elliott DC, Brennan P, Chowtur V (1990) Clin Chem Acta 194: 167CrossRefGoogle Scholar
  64. 64.
    Exley C, Birchall JD (1992) Polyhedron 11: 1901CrossRefGoogle Scholar
  65. 65.
    Calabrese EJ, Baldwin LA (2001) Trends Pharmacol Sci 22: 285CrossRefGoogle Scholar
  66. 66.
    Moody JR (1982) Anal Chem 54: 1358 ACrossRefGoogle Scholar
  67. 67.
    Scholze H (1988) Glass: Natur, Struktur und Eigenschaften. Springer, Berlin Heidelberg, New YorkGoogle Scholar
  68. 68.
    Fujiwara S, Narasaki H (1961) Japan Analyst 10: 1268Google Scholar
  69. 69.
    Moody JR, Lindstrom RM (1977) Anal Chem 49: 2264CrossRefGoogle Scholar
  70. 70.
    Fujiwara S, Narasaki H (1964) Anal Chem 36: 206CrossRefGoogle Scholar
  71. 71.
    Smith EJ, Nash RJ (1986) Elastomeric Closures for Parenterals. In: Pharmaceutical dosage forms: Parenteral Medications, vol 2. Marcel Dekker, New York, p 155Google Scholar
  72. 72.
    Bacon FR (1986) Glass Containers for Parenterals. In: Pharmaceutical dosage forms: Parenteral Medications, vol 2. Marcel Dekker, New York, p 85Google Scholar
  73. 73.
    Bohrer D, do Nascimento PC, Binotto R, Pomblum SC (2001) Trace Elem Med Biol 15: 95CrossRefGoogle Scholar
  74. 74.
    Bohrer D, do Nascimento PC, Binotto R, Carlesso R (2001) Trace Elem Med Biol 15: 103CrossRefGoogle Scholar
  75. 75.
    Tschöpel P, Kotz L, Schulz W, Veber M, Tölg G (1980) Fresenius J Anal Chem 302: 1CrossRefGoogle Scholar
  76. 76.
    Solomon DD, Jurgens RW, Wong KM (1986) Plastic Containers for Parenteral. In: Pharmaceutical dosage forms: Parenteral Medications, vol 2. Marcel Dekker, New York, p 111Google Scholar
  77. 77.
    Ullman’s Encyclopedia of Industrial Chemistry (1982) 5th edition, vol 19, Wiley-VCH, WeinheimGoogle Scholar
  78. 78.
    Exley C, Birchall JD (1996) J Inorg Biochem 63: 241CrossRefGoogle Scholar
  79. 79.
    Milliner DS, Shinaberger JH, Shuman P, Coburn J (1985) New Engl J Med 312: 165CrossRefGoogle Scholar
  80. 80.
    Klein GL (1991) Nutr Rev 49: 74CrossRefGoogle Scholar
  81. 81.
    Gammelgaard B, Sandberg E (1989) Trace Elem Electrolytes Health Dis 3: 39Google Scholar
  82. 82.
    Baydar T, Aydin A, Duru S, Isimer A, Sahin G (1997) Clin Toxicol 35: 277Google Scholar
  83. 83.
    Meldrum RD (2001) J Biomed Mater Res 57: 59CrossRefGoogle Scholar
  84. 84.
    Cabezuelo ABS, Bayón MM, González EB, Alonso JIG, Sanz-Medel A (1998) Analyst 123: 865CrossRefGoogle Scholar
  85. 85.
    Bantan T, Milaèiè R, Philar B (1998) Talanta 47: 929CrossRefGoogle Scholar
  86. 86.
    Rowatt E, Williams RJP (1996) Coord Chem Rev 149: 167Google Scholar
  87. 87.
    Hughes RC, Mürau PC, Gundersen G (1971) Anal Chem 43: 691CrossRefGoogle Scholar
  88. 88.
    Fernández-Martín JL, Menéndez-Fraga P, Canteros MA, Díaz-Lóopez JB, Cannata-Andía JB (1994) Clin Chim Acta 230: 137CrossRefGoogle Scholar
  89. 89.
    Wróbel K, González EB, Sanz-Medel A (1993) J Anal At Spectr 8: 915CrossRefGoogle Scholar
  90. 90.
    Menéndez-Fraga P, Fernández-Martín JL, González EB, Cannata-Andia JB (1998) Clin Chem 44: 1262Google Scholar
  91. 91.
    Canteros-Picotto A, Fernández-Martín JL, Cannata-Andia JB (2000) Am J Kidney Dis 36: 969CrossRefGoogle Scholar
  92. 92.
    Polak TB, Milaèiè R, Mitroviè B, Benedik M (2001) J Pharm Biomed Anal 26: 189CrossRefGoogle Scholar
  93. 93.
    Bohrer D, do Nascimento PC, Pomblum SG (1998) J Anal Atom Spectr 13: 635CrossRefGoogle Scholar
  94. 94.
    Bohrer do Nascimento D, Garcia SC, Gioda A (1997) Química Nova 20: 407Google Scholar
  95. 95.
    Valkonen S, Aitio A (1997) Sci Total Environ 199: 103CrossRefGoogle Scholar
  96. 96.
    Gitelman HJ, Alderman FR, Kurs-Lasky M, Rockette HE (1995) Ann Occup Hyg 39: 181Google Scholar
  97. 97.
    Sato M, Yoshimura H, Shimmura T, Obi H, Hatakeyama S, Kaneko E, Hoshino H, Yotsuyanagi (1997) J Chrom A 789: 361CrossRefGoogle Scholar
  98. 98.
    van Rensburg SJ, Potocnik FCV, Kiss T, Hugo F, van Zijl, Mansvelt E, Carstens ME, Theodorou P, Hurly PR, Emsley RA, Taljaard JJF (2001) Brain Res Bull 55: 319CrossRefGoogle Scholar
  99. 99.
    Mathieu C, Mathieu H (1995) Clin Chem 41: 625Google Scholar
  100. 100.
    Takatsu A, Eyama S, Uchiumi A (1995) Chromatographia 40: 125CrossRefGoogle Scholar
  101. 101.
    Wu J, Zhou CY, Chi H, Wong MK, Lee HK, Ong HY, Ong CN (1995) J Chrom B 663: 247CrossRefGoogle Scholar
  102. 102.
    Hewitt CD, Winborne K, Margrey D, Nicholson JRP, Savory MG, Savory J, Wills MR (1990) Clin Chem 36: 1466Google Scholar
  103. 103.
    Granadillo VA, Tahán JE, Salgado O, Elejalde LE, Rodríguez-Iturbe B, Romero GB, Romero RA (1995) Clin Chim Acta 233: 47CrossRefGoogle Scholar
  104. 104.
    Tang S, Parsons PJ, Slavin W (1996) Analyst 121: 195CrossRefGoogle Scholar
  105. 105.
    Nordahl K, Radziuk B, Thomassen Y, Weberg R (1990) Fresenius J Anal Chem 337: 310CrossRefGoogle Scholar
  106. 106.
    Pierson KB, Evenson MA (1986) Anal Chem 58: 1744CrossRefGoogle Scholar
  107. 107.
    Domingo JL, Gomez M, Llobet JM, Corbella, J (1991) Kidney Int 39: 598CrossRefGoogle Scholar
  108. 108.
    Gómez, M, Esparza JL, Domingo, JL, Singh PK, Jones MM (1999) Toxicology 137: 161CrossRefGoogle Scholar
  109. 109.
    Constantini, S, Giordano R, Ioppolo A, Mantovani A, Ballanti P, Mocetti P, Bonucci E (1989) Pharm & Toxicol 64: 47CrossRefGoogle Scholar
  110. 110.
    Schetinger MRC, Bonan CD, Morsch VM, Bohrer D, Valentim LM, Rodrigues SR (1999) Braz J Med Biol Res 32: 761CrossRefGoogle Scholar
  111. 111.
    Spectrochimica Acta PartB (1998) 53Google Scholar
  112. 112.
    Savory J, Herman MM (1999) Ann Clin Lab Sci 29: 118Google Scholar
  113. 113.
    Versieck J, Cornelis R (1980) Anal Chim Acta 116: 217CrossRefGoogle Scholar
  114. 114.
    Schaller KH, Valentin H (1984) Aluminum. In: Alessio L, Berlin A, Boni M, Roi R (eds), Biological indicators for the assessment of human exposure to industrial chemicals. Commission of the European Communities, p 21Google Scholar
  115. 115.
    Muniz CS, Marchante-Gayón JM, Alonso JIG, Sanz-Medel A (1998) J Anal At Spectr 13: 283CrossRefGoogle Scholar
  116. 116.
    van Landeghem GF, DHaese PC, Lamberts LV Barata JD, DeBroe ME (1997) Nephrol Dialysis Transplant 12: 1692CrossRefGoogle Scholar
  117. 117.
    Gauthier E, Fortier I, Courchesne F, Pepin P, Mortimer J, Gauvreau D (2000) Environ Res 84: 234CrossRefGoogle Scholar
  118. 118.
    Desroches S, Daydé S, Berthon G (2000) J Inorg Biochem 81: 301CrossRefGoogle Scholar
  119. 119.
    Desroches S, Biron F, Berthon G (1999) J Inorg Biochem 75: 27CrossRefGoogle Scholar
  120. 120.
    Venturini-Soriano M, Berthon G (1998) J Inorg Biochem 71: 135CrossRefGoogle Scholar
  121. 121.
    Venturini M, Berthon G (1989) J Inorg Biochem 37: 69CrossRefGoogle Scholar
  122. 122.
    Xie XZ, Yokel RA, Markesbery WR (1994) Biol Tr Elem Res 40: 39CrossRefGoogle Scholar
  123. 123.
    Ittel TH, Steinhausen C, Kislinger G, Kinzel S, Nolte E, Sieberth HG (1997) Nephrol Dialysis Transplant 12: 1369CrossRefGoogle Scholar
  124. 124.
    King SJ, Oldham C, Popplewell JF, Carling RS, Day JP, Fifeld LK, Cresswell RG, Liu KX, di Tata ML (1997) Analyst 122: 1049CrossRefGoogle Scholar
  125. 125.
    Moore PB, Day JP, Taylor GA, Ferrier IN, Fifeld LK, Edwardson JA (2000) Dementia Geriatr Cognit Disord 11: 66CrossRefGoogle Scholar
  126. 126.
    Yokel RA, Allen DD, Ackley DC (1999) J Inorg Biochem 76: 127CrossRefGoogle Scholar
  127. 127.
    Brauer RD, Robertson JD, Sharma P, Yokel RA (1999) Nucl Instr Meth Phys Res 152: 129CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2002

Authors and Affiliations

  • Maria Rosa Chitolina Schetinger
    • 1
  • Vera Maria Morsch
    • 1
  • Denise Bohrer
    • 1
  1. 1.Departamento de Química, CCNEUniversidade Federal de Santa MariaRSBrazil

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