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Production of Microbial Polyester by Fermentation of Recombinant Microorganisms

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Biopolyesters

Part of the book series: Advances in Biochemical Engineering/Biotechnology ((ABE,volume 71))

Abstract

Polyhydroxyalkanoates (PHAs) can be produced from renewable sources and are biodegradable with similar material properties and processibility to conventional plastic materials. With recent advances in our understanding of the biochemistry and genetics of PHA biosynthesis and cloning of the PHA biosynthesis genes from a number of different bacteria, many different recombinant bacteria have been developed to improve PHA production for commercial applications. For enhancing PHA synthetic capacity, homologous or heterologous expression of the PHA biosynthetic enzymes has been attempted. Several genes that allow utilization of various substrates were transformed into PHA producers, or non-PHA producers utilizing inexpensive carbon substrate were transformed with the PHA biosynthesis genes. Novel PHAs have been synthesized by introducing a new PHA biosynthesis pathway or a new PHA synthase gene. In this article, recent advances in the production of PHA by recombinant bacteria are described.

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Authors and Affiliations

  1. Department of Chemical Engineering and BioProcess Engineering Research Center, Korea Advanced Institute of Science and Technology, 373-1 Kusong-dong, Yusong-gu, Taejon, 305-701, Korea

    Sang Yup Lee & Jong-il Choi

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  1. Sang Yup Lee
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  2. Jong-il Choi
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Editors and Affiliations

  1. Sektion Umweltmikrobiologie, UFZ-Umwelt forschungszentrum Leipzig-Halle GmbH, Permoserstr. 15, 04318, Leipzig, FRG

    Wolfgang Babel

  2. Institut für Mikrobiologie, Westf. Wilhelms-Universität Münster, Corrensstr. 3, 48149, Münster, FRG

    Alexander Steinbüchel

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Lee, S.Y., Choi, Ji. (2001). Production of Microbial Polyester by Fermentation of Recombinant Microorganisms. In: Babel, W., Steinbüchel, A. (eds) Biopolyesters. Advances in Biochemical Engineering/Biotechnology, vol 71. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-40021-4_6

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  • DOI: https://doi.org/10.1007/3-540-40021-4_6

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  • Print ISBN: 978-3-540-41141-3

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