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Membrane-Assisted Extractive Bioconversions

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Process Integration in Biochemical Engineering

Part of the book series: Advances in Biochemical Engineering/Biotechnology ((ABE,volume 80))

Abstract

This chapter summarizes the use of membrane reactors in extractive bioconversions as process integration systems leading to in situ product recovery. Several membrane reactor configurations are analyzed, taking into account the type of bioconversion, biocatalyst type and location (either in the aqueous phase or in the membrane), membrane chemistry and morphology, solvent (extractant) type and its biocompatibility. Modeling of liquid-liquid extractive membrane bioreactors operation is also analyzed considering kinetics and mass-transfer aspects. The chapter includes examples from the authors’ laboratory as well as other published in the field. Both enzyme and whole cell-based bioconversions are considered. Relevant aspects related to the solvent (extractant) toxicity and how the membrane could protect the biocatalytic activity are analyzed. Trends in this field are also given.

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Authors and Affiliations

  1. Center for Biological and Chemical Engineering, Instituto Superior Técnico, Av. Rovisco Pais, 1049-001, Lisboa, Portugal

    Pedro Fernandes, Duarte M. F. Prazeres & Joaquim M. S. Cabral

  2. Universidade Lusófona de Humanidades e Tecnologias, Av. do Campo Grande 376, 1749-024, Lisboa, Portugal

    Pedro Fernandes

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  1. Pedro Fernandes
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  2. Duarte M. F. Prazeres
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  3. Joaquim M. S. Cabral
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Editors and Affiliations

  1. Laboratory of Chemical and Biochemical Engineering, Swiss Federal Institute of Technology (EPFL), 1015, Lausanne, Switzerland

    Urs. von Stockar

  2. Kluyver Laboratory for Biotechnology, Delft University of Technology, Julianalaan 67, 2628 BC, Delft, Netherlands

    L. A. M. van der Wielen

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Fernandes, P., Prazeres, D.M.F., Cabral, J.M.S. (2003). Membrane-Assisted Extractive Bioconversions. In: von Stockar, U., et al. Process Integration in Biochemical Engineering. Advances in Biochemical Engineering/Biotechnology, vol 80. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-36782-9_4

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  • DOI: https://doi.org/10.1007/3-540-36782-9_4

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