Keywords
- Rectal Cancer
- Clin Oncol
- Radiat Oncol Biol Phys
- Eastern Cooperative Oncology Group Performance Status
- Radiation Pneumonitis
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References
Airoldi M, Cortesina G, Giordano C et al (2004) Postoperative adjuvant chemoradiotherapy in older patients with head and neck cancer. Arch Otolaryngol Head Neck Surg 130:161–166
Allal AS, Obradovic M, Laurencet F et al (1999) Treatment of anal carcinoma in the elderly: feasibility and outcome of radical radiotherapy with or without concomitant chemotherapy. Cancer 85:26–31
Ampil FL, Mills GM, Stucker FJ et al (2001) Radical combined treatment of locally extensive head and neck cancer in the elderly. Am J Otolaryngol 22:65–69
Atagi S, Kawahara M, Ogawara M et al (2000) Phase II trial of daily low-dose carboplatin and thoracic radiotherapy in elderly patients with locally advanced non-small cell lung cancer. Jpn J Clin Oncol 30:59–64
Atagi S, Kawahara M, Tamura T et al (2005) Standard thoracic radiotherapy with or without concurrent daily lowdose carboplatin in elderly patients with locally advanced non-small cell lung cancer: a phase III trial of the Japan Clinical Oncology Group (JCOG9812). Jpn J Clin Oncol 35:195–201
Baumann M (1998) Is curative radiation therapy in elderly patients limited by increased normal tissue toxicity? Radiother Oncol 46:225–227
Berkman B, Rohan B, Sampson S (1994) Myths and biases related to cancer in the elderly. Cancer 74:2004–2008
Boehler FK, Rhomberg W, Doringer W (1992) Hypertension as risk factor for radiation induced side-effects in breast cancer. Strahlenther Onkol 168:344–349
Brandes AA, Vastola F, Basso U et al (2003) A prospective study on glioblastoma in the elderly. Cancer 97:657–662
Charlson ME, Pompei P, Ales KL et al. (1987) A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40:373–383
Charnley N, Choudhury A, Chesser P et al (2005) Effective treatment of anal cancer in the elderly with low-dose chemotherapy. Br J Cancer 92:1221–1225
Clark AJ, Stockton D, Elder A et al (2004) Assessment of outcomes after colorectal cancer resection in the elderly as a rationale for screening and early detection. Br J Surg 91:1345–1351
Cunningham MJ, Goyer RP, Gibbons SK et al (1997) Primary radiation, cisplatin, and 5-fluorouracil for advanced squamous carcinoma of the vulva. Gynecol Oncol 66:258–261
DeAngelis LM (2000) Radiotherapy of the brain in elderly patients. Arbiter. Eur J Cancer 36:451–452
Edwards B, Howe HL, Ries L et al (2002) Annual report to the nation on the status of cancer, 1973–1999, featuring implications of age and aging on U.S. cancer burden. Cancer 94:2766–2792
Geinitz H, Zimmermann FB, Molls M (1999) Strahlentherapie des alten Patienten. Verträglichkeit und Ergebnisse der Strahlentherapie älterer Personen. Strahlenther Onkol 175(3):119–127
Geinitz H, Zimmermann F, Thamm R et al (2005) 3-D conformal radiation therapy for prostate cancer in elderly patients. Radiother Oncol 76:27–34
Goffin JR, Rajan R, Souhami L (2004) Tolerance of radiotherapy and chemotherapy in elderly patients with bladder cancer. Am J Clin Oncol 27:172–177
Herold DM, Hanlon AL, Hanks GE (1999) Diabetes mellitus: a predictor for late radiation morbidity. Int J Radiat Oncol Biol Phys 43(3):475–479
Hutchins LF, Unger JM, Crowley JJ et al (1999) Underrepresentation of patients 65 years of age or older in cancer-treatment trials. N Engl J Med 341:2061–2067
Jeremic B, Shibamoto Y, Milicic B et al (1999a) A phase II study of concurrent accelerated hyperfractionated radiotherapy and carboplatin/oral etoposide for elderly patients with stage III non-small-cell lung cancer. Int J Radiat Oncol Biol Phys 44:343–348
Jeremic B, Shibamoto Y, Milicic B et al (1999b) Short-term chemotherapy and palliative radiotherapy for elderly patients with stage IV non-small cell lung cancer: a phase II study. Lung Cancer 24:1–9
Kodaira T, Fuwa N, Furutani K et al (2005) Phase I trial of weekly docetaxel and concurrent radiotherapy for head and neck cancer in elderly patients or patients with complications. Jpn J Clin Oncol 35:173–176
Mehta V (2005) Radiation pneumonitis and pulmonary fibrosis in non-small-cell lung cancer: pulmonary function, prediction and prevention. Int J Radiat Oncol Biol Phys 63:5–24
Merchant TE, McCormick B, Yahalom J et al (1996) The influence of older age on breast cancer treatment decisions and outcome. Int J Radiat Oncol Biol Phys 34:565–570
Nallapareddy S, Wilding GE, Yang G et al (2005) Chemoradiation is a tolerable therapy for older adults with esophageal cancer. Anticancer Res 25:3055–3060
Neugut AI, Fleischauer AT, Sundararajan V et al (2002) Use of adjuvant chemotherapy and radiation therapy for rectal cancer among the elderly: a population-based study. J Clin Oncol 20:2643–2650
Ogle KS, Swanson GM, Woods N et al (2000) Cancer and comorbidity: redefining chronic diseases. Cancer 88:653–663
Patel B, Forman J, Fontana J et al (2005) A single institution experience with concurrent capecitabine and radiation therapy in weak and/or elderly patients with urothelial cancer. Int J Radiat Oncol Biol Phys 62:1332–1338
Pignon T, Horiot JC, Van den BW et al (1996) No age limit for radical radiotherapy in head and neck tumours. Eur J Cancer 32A:2075–2081
Pignon T, Horiot JC, Bolla M et al (1997) Age is not a limiting factor for radical radiotherapy in pelvic malignancies. Radiother Oncol 42:107–120
Pignon T, Gregor A, Schaake KC et al (1998) Age has no impact on acute and late toxicity of curative thoracic radiotherapy. Radiother Oncol 46:239–248
Rice DC, Correa AM, Vaporciyan AA et al (2005) Preoperative chemoradiotherapy prior to esophagectomy in elderly patients is not associated with increased morbidity. Ann Thorac Surg 79:391–397
Samet J, Hunt WC, Key C et al (1986) Choice of cancer therapy varies with age of patient. J Am Med Assoc 255:3385–3390
Schild SE, Stella PS, Geyer SM et al (2003) The outcome of combined-modality therapy for stage III non-small-cell lung cancer in the elderly. J Clin Oncol 21:3201–3206
Schrag D, Gelfand SE, Bach PB et al (2001) Who gets adjuvant treatment for stage II and III rectal cancer? Insight from surveillance, epidemiology, and end results-Medicare. J Clin Oncol 19:3712–3718
Uno T, Isobe K, Kawakami H et al (2004) Efficacy and toxicities of concurrent chemoradiation for elderly patients with esophageal cancer. Anticancer Res 24:2483–2486
Valentini V, Morganti AG, Luzi S et al (1997) Is chemoradiation feasible in elderly patients? A study of 17 patients with anorectal carcinoma. Cancer 80:1387–1392
Wylie JP, Cowan RA, Deakin DP (1998) The role of radiotherapy in the treatment of localised intermediate and high grade non-Hodgkin’s lymphoma in elderly patients. Radiother Oncol 49:9–14
Yancik R, Ries L (1994) Cancer in older persons. Magnitude of the problem: How do we apply what we know? Cancer 74:1995–2003
Yuen AR, Zou G, Turrisi AT et al (2000) Similar outcome of elderly patients in Intergroup Trial 0096. Cisplatin, etoposide, and thoracic radiotherapy administered once or twice daily in limited small cell lung carcinoma. Cancer 89:1953–1960
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Geinitz, H. (2006). Feasibility of Combined Chemo- and Radiation Treatment in Elderly/Comorbid Patients. In: Brown, J.M., Mehta, M.P., Nieder, C. (eds) Multimodal Concepts for Integration of Cytotoxic Drugs. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-35662-2_22
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