Advertisement

Chimerische Virosomen sind starke immuntherapeutische Vektoren

  • M. AdaminaEmail author
  • R. Schumacher
  • R. Zurbriggen
  • M. Amacker
  • G. Spagnoli
  • M. Heberer
Conference paper
Part of the Deutsche Gesellschaft für Chirurgie book series (DTGESCHIR, volume 35)

Literatur

  1. 1.
    Zajac P, Oertli D, Marti W, Adamina M, Bolli M, Gueller U, Noppen C, Padovan E, Schultz-Thater E, Heberer M, Spagnoli G (2003) Phase I/II clinical trial of a non-replicative vaccinia virus expressing multiple HLA-A0201 restricted tumor associated epitopes and costimulatory molecules in metastatic melanoma patients. Hum Gene Ther 14: 1497–1510PubMedCrossRefGoogle Scholar
  2. 2.
    Adamina M, Oertli D (2005) Active specific immunotherapy of melanoma: lessons from the first decade. Swiss Med Wkly 135: 212–221PubMedGoogle Scholar
  3. 3.
    Adamina M, Bolli M, Albo F, Cavazza A, Zajac P, Padovan E, Schumacher R, Reschner A, Feder C, Marti WR, Oertli D, Heberer M, Spagnoli GC (2004) Encapsulation into sterically stabilized liposomes improves the immunogenicity of melanoma associated Mart-1/Melan-A epitopes. Br J Cancer 90: 263–269PubMedCrossRefGoogle Scholar
  4. 4.
    Schumacher R, Adamina M, Zurbriggen R, Bolli M, Padovan E, Zajac P, Heberer M, Spagnoli GC (2004) Influenza virosomes enhance class I restricted CTL induction through CD4+ T cell activation. Vaccine 22: 715–724CrossRefGoogle Scholar
  5. 5.
    Schumacher R, Zurbriggen R, Rosenthal R, Oertli D, Spagnoli GC, Heberer M and Adamina M (2005) Chimeric virosomes are powerful adjuvants in the induction of cytotoxic T cell responses against human tumor associated antigens. Vaccine 23: 5572–5582PubMedCrossRefGoogle Scholar

Copyright information

© Springer Medizin Verlag Heidelberg 2006

Authors and Affiliations

  • M. Adamina
    • 1
    Email author
  • R. Schumacher
    • 1
  • R. Zurbriggen
    • 2
  • M. Amacker
    • 2
  • G. Spagnoli
    • 1
  • M. Heberer
    • 1
  1. 1.Institut für Chirurgische Forschung und SpitalmanagementUniversitätsspital BaselBaselSchweiz
  2. 2.Pevion BiotechBümplizSchweiz

Personalised recommendations