19.10 Conclusions
fMRI has proved to be a reliable, safe, reproducible method with which to presurgically define eloquent areas. This technique gives us the opportunity to know in advance the actual situation of a lesion so that the surgeonsmay plan their approach strategy. This technique also allows the establishment of a presurgical evaluation of risk and enables the patient to be fully aware at the moment of informed consent. Despite the increase in its clinical applications, fMRI is still underused in the clinical field and should be performed almost routinely before surgery.
Keywords
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Alkadhi H, Kollias SS, Crelier GR, et al. (2000) Plasticity of the human motor cortex in patients with arteriovenous malformations: a functional MR imaging study. AJNR 21:1423–1433
Baxendale S (2002) The role of functional MRI in the presurgical investigation of temporal lobe epilepsy patients: a clinical perspective and review. J Clin Exp Neuropsychol 24:664–676
Bogomolny DL, Petrovich NM, Hou BL, et al. (2004) Functional MRI in the brain tumor patients. Top Magn Reson Imaging 14:325–335
Baumgartner C, Barth DS, Levesque MF, et al. (1992) Human hand and lip sensorimotor cortex as studied on electrocorticography. Electroencephalogr Clin Neurophysiol 84:115–126
Cabeza R, Nyberg L (2000) Imaging cognition II: an empirical review of 275 PET and fMRI studies. J Cogn Neurosci 12:1–47
Cannestra AF, Pouratian N, Forage J, et al. (2004) Functional magnetic resonance imaging and optical imaging for dominant-hemisphere perisylvian arteriovenous malformations. Neurosurgery 55:804–814
Cevolani D, Agati R, Albini Riccioli L, et al. (2004) Pre-surgical use of functional paradigms in brain fMRI mapping: our initial 3T experience. Rivista di Neuroradiologia 17:836–848
Donaldson DI, Buckner RL (2004) Effective paradigm design. In: Jezzard P, Matthews PM, Smith SM (eds) Functional MRI. An introduction to methods. Oxford University Press, Oxford
Fried I, Nenov VI, Ojermann SG, et al. (1995) Functional MR and PET imaging of rolandic and visual cortices for neurosurgical planning. J Neurosurg 83:854–861
Friston K, Holmes A, Poline J-B, et al. (1995) Analysis of fMRI time series revisited. Neuroimage 2:45–53
Golby AJ, Poldrack RA, Illes J, et al. (2002) Memory lateralization in medial temporal lobe epilepsy assessed by functional MRI. Epilepsia 43:855–863
Haglund MM, Berger MS, Mitchel S, et al. (1994) Cortical localization of temporal lobe language sites in patients with gliomas. Neurosurgery 34:567–576
Holodny AI (2004) Preoperative and postoperative mapping of eloquent regions in the brain. ASNR:33–36
Holodny AI, Schulder M, Ybasco A, et al. (2002) Translocation of Broca’s area to the contralateral hemisphere as the result of the growth of a left inferior frontal glioma. J Comput Assist Tomogr 26:941–943
Holodny AI, Schulder M, Liu WC, et al. (2000) The effect of brain tumors on BOLD functional MR imaging activation in the adjacent cortex: implications for image-guided neurosurgery. AJNR 21:1415–1422
Hu X, Norris D (2004) Advances in high-field magnetic resonance imaging. Annu Rev Biomed Eng 6:157–184
Kim SG, Ashe J, Hendrich K, et al. (1993) Functional magnetic resonance imaging of motor cortex: hemispheric asymmetry and handedness. Science 261:615–617
Kollias SS, Landau K, Khan N, et al. (1998) Functional evaluation using magnetic resonance imaging of the visual cortex in patients with retrochiasmatic lesions. J Neurosurg 89:780–790
Krings T, Topper R, Reinges MH, et al. (2000) Hemodynamic changes in simple partial epilepsy: a functional fMRI study. Neurology 54:524–527
Lemieux L, Hammers A, Mackinnon T, et al. (2003) Automatic segmentation of the brain and intracranial cerebrospinal fluid in T1-weighted volume MRI scans of the head, and its application to serial cerebral and intracranial volumetry. Magn Res Med 49:872–884
Leonardi M, Agati R, Cevolani D, et al. (2004) Potential impact of advanced 3 Tesla diagnostics in the management of patients with brain tumours. Rivista di Neuroradiologia 17:849–881
Lin W, An H, Chen Y, et al. (2003) Practical consideration for 3T imaging. Magn Reson Imaging Clin N Am 11:615–639
Liu TT, Frank LR, Wong EC, et al. (2001) Detection power, estimation efficiency, and predictability in event-related fMRI. Neuroimage 13:759–773
Mast H, Mohr JP, Osipov A, et al. (1995) Steal is an unestablished mechanism for the clinical presentation of cerebral arteriovenous malformations. Stroke 26:1215–1220
Matthews PM (2004) An introduction to functional magnetic resonance in the brain. In: Jezzard P, Matthews PM, Smith SM (eds) Functional MRI. An introduction to methods. Oxford University Press, Oxford
Moritz C, Haughton V (2003) Functional MR imaging: paradigms for clinical preoperative mapping. Magn Reson Imaging Clin N Am 11:529–542
Petrovich NM, Holodny AI, Brennan CW, et al. (2004) Isolated translocation of Wernicke’s area to the right hemisphere in a 62-year-man with a temporo-parietal glioma. AJNR 25:130–133
Pouratian N, Bookheimer SY, Rex DE, et al. (2000) Utility of preoperative functional magnetic resonance imaging for identifying language cortices in patients with vascular malformations. J Neurosurg 97:21–32
Pujol J, Vendrell P, Deus J, et al. (1996) Frontal lobe activation during word generation studied by functional MRI. Acta Neurol Scand 93:403–410
Rao SM, Binder JR, Hammeke TA, et al. (1995) Somatotopic mapping of the human primary motor cortex with functional magnetic resonance imaging. Neurology 45:919–924
Schreiber A, Hubbe U, Ziyeh S, et al. (2000) The influence of gliomas and non-glial space occupying lesions on blood-oxygen-level-dependent contrast enhancement. AJNR 21:1055–1063
Sereno MI, Dale AM, Reppas JB, et al. (1995) Borders of multiple visual areas in humans, revealed by functional magnetic resonance imaging. Science 268:889–893
Singh LN, Higano S, Takahashi S, et al. (1998) Comparison of ipsilateral activation between right-and left-handers: a functional MR imaging study. Neuroreport 9:1861–1866
Sled JG, Zijdenbos AP, Evans AC (1998) A nonparametric method for automatic correction of intensity nonuniformity in MRI data. IEEE Trans Med Imaging 17:87–97
Smith SM (2004) Overview of fMRI analysis. In: Jezzard P, Matthews PM, Smith SM (eds) Functional MRI. An introduction to methods. Oxford University Press, Oxford
Sunaert S, Yousry TA (2001) Clinical applications of functional magnetic resonance imaging. Neuroimaging Clin N Am 11:221–236
Uematsu S, Lesser RP, Gordon B (1992) Localization of sensorimotor cortex: the influence of Sherrington and Cushing on the modern concept. Neurosurgery 30:904–913
Wexler BE, Fulbright RK, Lacadie CM, et al. (1997) An fMRI study of the human cortical motor system response to increasing functional demands. Magn Res Imaging 15:385–396
Woods RP, Grafton ST, Holmes CJ, et al. (1998) Automated image registration: I. General methods and intrasubject, intramodality validation. J Comput Assist Tomogr 22:139–152
Worsley KJ, Marrett S, Neelin P, et al. (1996) A unified statistical approach for determining significant signals in images of cerebral activation. Hum Brain Mapp 4:58–73
Worsley KJ, Friston KJ (1995) Analysis of fMRI time series revisited — again. Neuroimage 2:173–181
Yetkin FZ, Mueller WM, Hammeke TA, et al. (1995) Functional magnetic resonance imaging mapping of the sensorimotor cortex with tactile stimulation. Neurosurgery 36:921–925
Yoursy I, Naidich TP, Yoursy TA (2001) Functional magnetic resonance imaging. Factors modulating the cortical activation pattern of the motor system. Neuroimaging Clin N Am 11:195–202
Yoursy TA, Schmid UD, Alkadhi H, et al. (1997) Localization of the motor hand area to a knob on the precentral gyrus. Brain 120:141–157
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2006 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Cevolani, D., Agati, R., Leonardi, M. (2006). Use of fMRI Activation Paradigms: A Presurgical Tool for Mapping Brain Function. In: Salvolini, U., Scarabino, T. (eds) High Field Brain MRI. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-31776-7_19
Download citation
DOI: https://doi.org/10.1007/3-540-31776-7_19
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-31775-3
Online ISBN: 978-3-540-31776-0
eBook Packages: MedicineMedicine (R0)