Photopatch Testing

  • Roy A. Palmer
  • Ian R. White


Contact Dermatitis Tiaprofenic Acid Contact Allergy Minimum Erythema Dose Phototoxic Reaction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Darvay A, White IR, Rycroft RJ, Jones AB, Hawk JL, McFadden JP (2001) Photoallergic contact dermatitis is uncommon. Br J Dermatol 145:597–601PubMedCrossRefGoogle Scholar
  2. 2.
    Bruynzeel DP, Ferguson J, Andersen K, Goncalo M, English J, Goossens A, Holzle E, Ibbotson SH, Lecha M, Lehmann P, Leonard F, Moseley H, Pigatto P, Tanew A; European Taskforce for Photopatch Testing (2004) Photopatch testing: a consensus methodology for Europe. J Eur Acad Dermatol Venereol 18:679–682PubMedCrossRefGoogle Scholar
  3. 3.
    Wennersten G, Thune P, Brodthagen H, Jansen C, Rystedt I (1984) The Scandinavian multicenter photopatch study. Preliminary results. Contact Dermatitis 10:305–309PubMedCrossRefGoogle Scholar
  4. 4.
    Jansen CT, Wennersten G, Rystedt I, Thune P, Brodthagen H (1982) The Scandinavian standard photopatch test procedure. Contact Dermatitis 8:155–158PubMedCrossRefGoogle Scholar
  5. 5.
    Neumann NJ, Holzle E, Plewig G, Schwarz T, Panizzon RG, Breit R, Ruzicka T, Lehmann P (2000) Photopatch testing: the 12-year experience of the German, Austrian, and Swiss photopatch test group. J Am Acad Dermatol 42:183–192PubMedCrossRefGoogle Scholar
  6. 6.
    Pigatto PD, Legori A, Bigardi AS, Guarrera M, Tosti A, Santucci B, Monfrecola G, Schena D (1996) Gruppo Italiano Ricerca Dermatiti da Contatto ed Ambientali Italian Multicenter Study of Allergic Contact Photodermatitis: epidemiological aspects. Am J Contact Dermat 7:158–163PubMedCrossRefGoogle Scholar
  7. 7.
    British Photodermatology Group (1997) Photopatch testing: methods and indications. Br J Dermatol 136:371–376CrossRefGoogle Scholar
  8. 8.
    Bell HK, Rhodes LE (2000) Photopatch testing in photosensitive patients. Br J Dermatol 142:589–590PubMedCrossRefGoogle Scholar
  9. 9.
    Thune P, Jansen C, Wennersten G, Rystedt I, Brodthagen H, McFadden N (1988) The Scandinavian multicenter photopatch study 1980-1985: final report. Photodermatology 5:261–269PubMedGoogle Scholar
  10. 10.
    Bilsland D, Ferguson J (1993) Contact allergy to sunscreen chemicals in photosensitivity dermatitis/actinic reticuloid syndrome (PD/AR) and polymorphic light eruption (PLE). Contact Dermatitis 29:70–73PubMedCrossRefGoogle Scholar
  11. 11.
    DeLeo VA, Suarez SM, Maso MJ (1992) Photoallergic contact dermatitis. Results of photopatch testing in New York, 1985 to 1990. Arch Dermatol 128:1513–1518PubMedCrossRefGoogle Scholar
  12. 12.
    Fotiades J, Soter NA, Lim HW (1995) Results of evaluation of 203 patients for photosensitivity in a 7.3-year period. J Am Acad Dermatol 33:597–602PubMedCrossRefGoogle Scholar
  13. 13.
    Holzle E, Neumann N, Hausen B, Przybilla B, Schauder S, Honigsmann H, Bircher A, Plewig G (1991) Photopatch testing: the 5-year experience of the German, Austrian, and Swiss Photopatch Test Group. J Am Acad Dermatol 25:59–68PubMedCrossRefGoogle Scholar
  14. 14.
    Bryden AM, Ibbotson SH, Ferguson J (on behalf of the UK Multicentre Photopatch Group) (2003) Photopatch testing: results of the U.K. multicentre photopatch study. Br J Dermatol 149(Suppl 64):3 (abstract)Google Scholar
  15. 15.
    Berne B, Ros AM (1998) 7 years experience of photopatch testing with sunscreen allergens in Sweden. Contact Dermatitis 38:61–64PubMedGoogle Scholar
  16. 16.
    Wilkinson DS (1961) Photodermatitis due to tetrachlorsalicylanilide. Br J Dermatol 73:213–219PubMedGoogle Scholar
  17. 17.
    Larsen W (1978) Photoallergy to musk ambrette found in an aftershave lotion. Presented at the American Academy of Dermatology meeting, San Francisco, California, December 1978Google Scholar
  18. 18.
    Cronin E (1984) Photosensitivity to musk ambrette. Contact Dermatitis 11:88–92PubMedCrossRefGoogle Scholar
  19. 19.
    English JSC, White IR, Cronin E (1987) Sensitivity to sunscreens. Contact Dermatitis 17:159–162PubMedCrossRefGoogle Scholar
  20. 20.
    Schauder S, Ippen H (1997) Contact and photocontact sensitivity to sunscreens. Review of a 15-year experience and of the literature. Contact Dermatitis 37:221–232PubMedCrossRefGoogle Scholar
  21. 21.
    Ang P, Ng SK, Goh CL (1998) Sunscreen allergy in Singapore. Am J Contact Dermat 9:42–44PubMedCrossRefGoogle Scholar
  22. 22.
    Dromgoole SH, Maibach HI (1990) Sunscreening agent intolerance: contact and photocontact sensitization and contact urticaria. J Am Acad Dermatol 22:1068–1078PubMedGoogle Scholar
  23. 23.
    Horio T (1975) Chlorpromazine photoallergy. Coexistence of immediate and delayed type. Arch Dermatol 111:1469–1471PubMedCrossRefGoogle Scholar
  24. 24.
    Durieu C, Marguery MC, Giordano-Labadie F, Journe F, Loche F, Bazex J (2001) Photoaggravated contact allergy and contact photoallergy caused by ketoprofen: 19 cases. Ann Dermatol Venereol 128:1020–1024PubMedGoogle Scholar
  25. 25.
    Adamski H, Benkalfate L, Delaval Y, Ollivier I, le Jean S, Toubel G, le Hir-Garreau I, Chevrant-Breton J (1998) Photodermatitis from non-steroidal anti-inflammatory drugs. Contact Dermatitis 38:171–174PubMedGoogle Scholar
  26. 26.
    Durbize E, Vigan M, Puzenat E, Girardin P, Adessi B, Desprez PH, Humbert PH, Laurent R, Aubin F (2003) Spectrum of cross-photosensitization in 18 consecutive patients with contact photoallergy to ketoprofen: associated photoallergies to non-benzophenone-containing molecules. Contact Dermatitis 48:144–149PubMedCrossRefGoogle Scholar
  27. 27.
    Matthieu L, Meuleman L, Van Hecke E, Blondeel A, Dezfoulian B, Constandt L, Goossens A (2004) Contact and photocontact allergy to ketoprofen. The Belgian experience. Contact Dermatitis 50:238–241PubMedCrossRefGoogle Scholar
  28. 28.
    Lovell CR (1993) Plants and the skin, 1st edn. Blackwell Scientific Publications, Oxford, UKGoogle Scholar
  29. 29.
    De Groot AC, Weyland JW, Nater JP (1994) Unwanted effects of cosmetics and drugs used in dermatology, 3rd edn. Elsevier, Amsterdam, The Netherlands, pp 136–154Google Scholar
  30. 30.
    Goossens A (2004) Photoallergic contact dermatitis. Photodermatol Photoimmunol Photomed 20:121–125PubMedCrossRefGoogle Scholar
  31. 31.
    Bosca F, Miranda MA, Carganico G, Mauleon D (1994) Photochemical and photobiological properties of ketoprofen associated with the benzophenone chromophore. Photochem Photobiol 60:96–101PubMedGoogle Scholar
  32. 32.
    Dooms-Goossens A, Chrispeels MT, De Veylden H, Roelandts R, Willems L, Degreef H (1987) Contact and photocontact sensitivity problems associated with thiourea and its derivatives: a review of the literature and case reports. Br J Dermatol 116:573–579PubMedGoogle Scholar
  33. 33.
    Duguid C, O’Sullivan D, Murphy GM (1993) Determination of threshold UV-A elicitation dose in photopatch testing. Contact Dermatitis 29:192–194PubMedCrossRefGoogle Scholar
  34. 34.
    Hasan T, Jansen CT (1996) Photopatch test reactivity: effect of photoallergen concentration and UVA dosaging. Contact Dermatitis 34:383–386PubMedCrossRefGoogle Scholar
  35. 35.
    Addo HA, Sharma SC, Ferguson J, Johnson BE, Frain-Bell W (1985) A study of compositae plant extract reactions in photosensitivity dermatitis. Photodermatology 2:68–79PubMedGoogle Scholar
  36. 36.
    Collins P, Ferguson J (1994) Photoallergic contact dermatitis to oxybenzone. Br J Dermatol 131:124–129PubMedGoogle Scholar
  37. 37.
    DeLeo V, Gonzalez E, Kim J, Lim H (2000) Phototesting and photopatch testing: when to do it and when not to do it. Am J Contact Dermat 11:57–61PubMedCrossRefGoogle Scholar
  38. 38.
    Hölzle E, Plewig G, Lehmann P (1987) Photodermatoses — diagnostic procedures and their interpretation. Photodermatology 4:109–114PubMedGoogle Scholar
  39. 39.
    Bourrain JL, Paillet C, Woodward C, Beani JC, Amblard P (1997) Diagnosis of photosensitivity to flupenthixol by photoprick testing. Photodermatol Photoimmunol Photomed 13:159–161PubMedGoogle Scholar
  40. 40.
    Neumann NJ, Holzle E, Lehmann P, Benedikter S, Tapernoux B, Plewig G (1994) Pattern analysis of photopatch test reactions. Photodermatol Photoimmunol Photomed 10:65–73PubMedGoogle Scholar
  41. 41.
    Kelly DA, Young AR, McGregor JM, Seed PT, Potten CS, Walker SL (2000) Sensitivity to sunburn is associated with susceptibility to ultraviolet radiation-induced suppression of cutaneous cell-mediated immunity. J Exp Med 191:561–566PubMedCrossRefGoogle Scholar
  42. 42.
    Polla L, Margolis R, Goulston C, Parrish JA, Granstein RD (1986) Enhancement of the elicitation phase of the murine contact hypersensitivity response by prior exposure to local ultraviolet radiation. J Invest Dermatol 86:13–17PubMedCrossRefGoogle Scholar
  43. 43.
    Yoshikawa T, Kurimoto I, Streilein JW (1992) Tumour necrosis factor-alpha mediates ultraviolet light B-enhanced expression of contact hypersensitivity. Immunology 76:264–271PubMedGoogle Scholar
  44. 44.
    Grabbe S, Steinbrink K, Steinert M, Luger TA, Schwarz T (1995) Removal of the majority of epidermal Langerhans cells by topical or systemic steroid application enhances the effector phase of murine contact hypersensitivity. J Immunol 155:4207–4217PubMedGoogle Scholar
  45. 45.
    Tie C, Golomb C, Taylor JR, Streilein JW (1995) Suppressive and enhancing effects of ultraviolet B radiation on expression of contact hypersensitivity in man. J Invest Dermatol 104:18–22PubMedCrossRefGoogle Scholar
  46. 46.
    Palmer RA, Hawk JLM, Young AR, Walker SL (2005) The effect of solar-simulated radiation on the elicitation phase of contact hypersensitivity does not differ between controls and patients with polymorphic light eruption. J Invest Dermatol 124:1308–1312PubMedCrossRefGoogle Scholar
  47. 47.
    Beattie PE, Traynor NJ, Woods JA, Dawe RS, Ferguson J, Ibbotson SH (2004) Can a positive photopatch test be elicited by subclinical irritancy or allergy plus suberythemal UV exposure? Contact Dermatitis 51:235–240PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2006

Authors and Affiliations

  • Roy A. Palmer
    • 1
  • Ian R. White
    • 2
  1. 1.St. Thomas’ HospitalDepartment of Photobiology, St. John’s Institute of DermatologyLondonUK
  2. 2.St. Thomas’ HospitalSt. John’s Institute of DermatologyLondonUK

Personalised recommendations