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References
Higuchi T (1960) Physical chemical analysis of percutaneous absorption process from creams and ointments. J Soc Cosmet Chem 11:85
Guy RH, Hadgraft J (1989) Mathematical models of percutaneous absorption. In: Bronaugh RL, Maibach HI (eds) Percutaneous absorption. Dekker, New York, p 13
Guy RH, Hadgraft J, Maibach AJ (1982) A pharmacokinetic model for percutaneous absorption. Int J Pharmaceut 11:119
Gupta SK et al (1993) Pharmokinetic and pharmodynamic modeling of transdermal products: in vivo methods, problems, and pitfalls. In: Shah VP, Maibach HI (eds) Topical drug bioavailability: bioequivalence and penetration. Plenum, New York, p 311
Kuboto K et al (1993) Percutaneous absorption: a single model. J Pharm Sci 82:450
Williams PL, Riviere JE (1995) A biophysically based dermatopharmokinetic compartment model for quantifying percutaneous penetration and absorption of topically applied agents. 1. Theory. J Pharm Sci 84:599
Jain MK (1980) In: Jain MK, Wagner RC (eds) Introduction to biological membranes. Wiley, Toronto, p 117
Gennis RB (1989) Biomembranes: molecular structure and function. Springer, Berlin Heidelberg New York
Barry BW (1983) Dermatological formulations: percutaneous absorption. Dekker, New York
Scheuplein RJ (1967) Mechanism of percutaneous absorption. II. Transient diffusion and the relative importance of various routes of skin penetration. J Invest Dermatol 45:334
Lieb WR, Stein WD (1986) Non-stokesian nature of transverse diffusion within human red blood cell membranes. J Membr Biol 92:111
Hatcher ME, Plachy WZ (1993) Dioxygen diffusion in the stratum corneum: an EPR study. Biochim Biophys Acta 1149:73
Packer KJ, Sellwood TC (1978) Proton magnetic resonance studies of hydrated stratum corneum, part 2. Self diffusion. J Chem Soc Faraday Trans 2:1592
Francoeur ML, Potts RO (1988) The perturbation of stratum corneum lipids affects the diffusive but not partitioning aspects of water vapor permeability. Pharm Res 5:S130
Brown S, Diffey BL (1986) The effect of applied thickness on sunscreen protection: in vivo and in vitro studies. Photochem Photobiol 44:509
Flynn GL (1993) General introduction and conceptual differentiation of topical and transdermal drug delivery systems. In: Shaw VP, Maibach HI (eds) Topical drug bioavailability: bioequivalence and penetration. Plenum, New York, p 369
Reifenrath WG (1995) Volatile substances. Cosmet Toil 110:85
Rolland A et al (1993) Site-specific drug delivery to pilosebaceous structures using polymeric microspheres. Pharm Res 10:1738
Rolland A (1993) Particulate carriers in dermal and transdermal drug delivery: myth or reality. In: Walters KA, Hadgraft J (eds) Pharmaceutical particulate carriers: therapeutic applications. Dekker, New York, p 1983
Schaefer H, Redelmeier TE (1996) Skin barrier principle of percutaneous absorption. Karger, Basel
Reichert U et al (1993) The cornified envelope: a key structure of terminally differentiating keratinocytes. In: Darmon M, Blumenberg M (eds) The keratinocytes. Academic, San Diego, p 107
Elias PM, Menon GK (1991) Structural and lipid biochemical correlates of the epidermal permeability barrier. Adv Lipid Res 24:1
Madison KC et al (1987) Presence of intact intercellular lipid lamallae in the upper layers of the stratum corneum. J Invest Dermatol 88:714
Hou SYE et al (1991) Membranes structures in normal and essential fatty acid deficient stratum corneum: characterization by ruthenium tetroxide staining and x-ray diffraction. J Invest Dermatol 96:215
Bouwstra JA et al (1991) Structure of human stratum corneum by small-angle x-ray scattering. J Invest Dermatol 97:1005
Bouwstra JA et al (1992) Structure of human stratum corneum as a function of temperature and hydration: a wide angle x-ray diffraction study. Int J Pharm 84:205
Rolland A et al (1993) Site-specific drug delivery to pilose-baceous structures using polymeric microspheres. Pharm Res 10:1738
Lademann J et al (2001) Investigation of follicular penetration of topically applied substances. Skin Pharmacol Appl Skin Physiol 14:17–22
Flynn GL (1990) Physiochemical determinants of skin absorption. In: Gerrity TR, Henry CJ (eds) Principles of route-to-route extrapolation for risk assessment. Elsevier, New York, p 93
Tayar EL et al (1991) Percutaneous penetration of drugs: a quantitative structure-permeability relationship study. J Pharm Sci 80:744
Kastings GB et al (1987) Effect of lipid sollubility and molecular size on percutaneous absorption. In: Shroot B, Schaefer H (eds) Skin pharmakinetics, vol 1. Karger, Basel, p 138
Guy RH, Potts RO (1992) Structure-permeability relationships in percutaneous absorption. J Pharm Sci 81:603
Nemaniac MK, Elias PM (1980) In situ precipitation: a novel cytochemical technique for visualization of permeability pathways in mammalian stratum corneum. J Histol Cytochem 28:573
Squier CA, Lesch CA (1988) Penetration pathways of different compounds through epidermis and oral epithelial. J Oral Pathol 17:512
Pinnagoda J et al (1990) Guidelines for transepithelial water loss (TEWL) measurements. A report from the Standardization Group of the European Society of Contact Dermatitis. Contact Derm 22:164
Lavrijsen APM et al (1993) Barrier function parameters in various keratization disorders: transepithelial water loss and vascular response to hexyl nicotinate. Br J Dermatol 129:547
Rougier A, Lotte C (1993) Predictive approaches: I. The stripping technique. In: Shaw VP, Maibach HI (eds) Topical drug bioavailability: bioequivalence and penetration. Plenum, New York, p 163
Scheuplein RJ (1967) Mechanism of percutaneous absorption. II. Transient diffusion and the relative importance of various routes of skin penetration. J Invest Dermatol 45:33
Boukhman MP, Maibach HI (2001) Thresholds in contact sensitisation: immunologic mechanisms and experimental evidence in humans — an overview. Food Chem Tox 39:1125–1134
Berard F, Marty JP, Nicolas JF (2003) Allergen penetration through the skin. Eur J Dermatol 13:324–330
Kao J, Carver MP (1990) Cutaneous metabolism of xenobiotics. Drug Metab Rev 22:363
Mukhtar H, Khan WA (1989) Cutaneous cytochrome P-450. Drug Metab Rev 20:657
Smith CK, Moore CA, Elahi EN, Smart AT, Hotchkiss SA (2000) Human skin absorption and metabolism of the contact allergens, cinnamic aldehyde, and cinnamic alcohol. Toxical Appl Pharmacol 168:189–199
Bodin A, Li Ping Shao J, Nilsson LG, Karlberg AT (2001) Identification and allergenic activity of hydroxyaldehydes-a new type of oxidation product from an ethoxylated non-ionic surfactant. Contact Dermatitis 44:207–212
Ryan TJ (1983) Cutaneous circulation. In: Goldsmith LA (eds) Biochemistry and physiology of the skin, vol 2. Oxford University Press, New York, p 817
Riviere JE, Williams PL (1992) Pharmokinetic implication of changing blood flow in skin. J Pharm Sci 81:601
Monteiro-Riviere NA et al (1990) Interspecies and interregional analysis of the comparative histological thickness and laser Doppler blood flow measurements af five cutaneous sites in nine species. J Invest Dermatol 95:582
Riviere JE et al (1991) The effect of vasoactive drugs on transdermal lidocaine iontophoresis. J Pharm Sci 80:615
Bos JD, Meinardi MMHM (2000) The 500 Dalton rule for the skin penetration of chemical compounds and drugs. Exp Dermatol 9:165–169
Smith Pease CK, White IR, Basketter DA (2002) Skin as route of exposure to protein allergens. Clin Exp Dermatol 27:296–300
Zhai H, Maibach HI (2001) Skin occlusion and irritant and allergic contact dermatitis: an overview. Contact Dermatitis 44:201–206
Pedersen LK et al (2004) Augmentation of skin response by exposure to a combination of allergens and irritants — a review. Contact Dermatitis 50:265–273
Hosoi J et al (2000) Regulation of the cutaneous allergic reaction by humidity. Contact Dermatitis 42:81–84
Cross SE, Roberts MS (2000) The effect of occlusion on epidermal penetration of parabens from a commercial allergy test ointment, acetone and ethanol vehicles. J Invest Derm 115:914–918
Williams ML, Elias PM (1993) From basket weave to barrier: unifying concepts for the pathogenesis of the disorders of cornification. Arch Dermatol 129:626
Oestmann E et al (1993) Skin barrier function in healthy volunteers as assessed by transepidermal water loss and vascular response to hexyl nicotinate: intra-and inter-individual variability. Br J Dermatol 128:130
Blichmann CW, Serup J (1989) Reproducibility and variability of transdermal water loss measurements. Acta Derm Venereol 67:206
Imokawa G et al (1991) Decreased levels of ceramides in stratum corneum of atopic dermatitis: an etiologic factor in atopic dry skin? J Invest Dermatol 96:523
Werner Y, Linberg M (1985) Transepidermal water loss in dry and clinically normal skin in patients with atopic dermatitis. Acta Derm Venereol 65:102
Takenouchi M, Suzuki H, Tagami H (1986) Hydration characteristics of pathological stratum corneum: evaluation of bound water. J Invest Dermatol 87:574–576
Werner Y, Linberg M (1985) Transepidermal water loss in dry and clinically normal skin in patients with atopic dermatitis. Acta Derma Venereol 65:102
Wilhelm KP et al (1991) Effect of sodium lauryl sulfate-induced skin irritation on in vivo percutaneous absorption of four drugs. J Invest Dermatol 97:927
Lavrijsen APM et al (1993) Barrier function parameters in various keratization disorders: transepithelial water loss and vascular response to hexyl nicotinate. Br J Dermatol 129:547
Lavrijsen APM et al (1995) Reduced skin barrier function parallels abnormal stratum corneum lipid organization in patients with lamellar ichtyosis. J Invest Dermatol 105:619
Fartasch M, Schnetz E, Diepgen TL (1998) Characterization of detergent-induced barrier alterations — effect of barrier cream on irritation. J Invest Dermatol 3:121–127
Wall LM (1980) Nickel penetration through rubber gloves. Contact Dermatitis 6:461–463
Kalimo K, Lammintausa K, Maki J, Teuho J, Jensen CT (1985) Nickel penetration in allergic individuals: bioavailability versus X-ray microanalysis detection. Contact Dermatitis 12:255–257
Fullerton A, Andersen JR, Hoelgaard A (1988) Permeation of nickel through human skin in vitro-effect of vehicles. Br J Dermatol 118:509–516
Fullerton A, Andersen JR, Hoelgaard A, Menne T (1986) Permeation of nickel salts through human skin in vitro. Contact Dermatitis 15:173–177
Sherertz EF, Sloan KB (1988) Percutaneous penetration of squaric acid and its esters in hairless mouse and human skin in vitro. Arch Dermatol Res 280:57–60
Surber C, Itin P, Buchner S, Maibach HI (1992) Effect of a new topical cyclosporin formulation on human allergic contact dermatitis. Contact Dermatitis 26:116–119
Loden M (1986) The effect of 4 barrier creams on the absorption of water, benzene, and formaldehyde into excised human skin. Contact Dermatitis 14:292–296
Boman A, Mellstrom G (1989) Percutaneous absorption of 3 organic solvents in the guinea pig. (III). Effect of barrier cream. Contact Dermatitis 21:134–140
Frosch PJ, Kurte A (1994) Efficacy of skin barrier creams (IV). The repetitive irritation test (RIT) with a set of 4 standard irritants. Contact Dermatitis 31:161–168
Zhai H, Maibach HI (1996) Effect of barrier creams: human skin in vivo. Contact Dermatitis 35:92–96
Zhai H, Maibach HI (1996) Percutaneous penetration (dermatopharmcokinetics) in evaluating barrier creams. Curr Prob Dermatol 25:193–205
Gawkrodger DJ, Healy J, Howe AM (1995) The prevention of nickel contact dermatitis. A review of the use of binding agents and barrier creams. Contact Dermatitis 32:257–265
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Schaefer, H., Redelmeier, T.E. (2006). Skin Penetration. In: Frosch, P.J., Menné, T., Lepoittevin, JP. (eds) Contact Dermatitis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-31301-X_11
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DOI: https://doi.org/10.1007/3-540-31301-X_11
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