Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Kaufman, S.: Aromatic amino acid hydroxylases. The Enzymes, 3rd Ed. (Boyer, P.D., Krebs, E.G., eds.), 18, 217–282 (1987)
Koizumi, S.; Matsushima, Y.; Nagatsu, T.; Linuma, H.; Takeuchi, T.; Umezawa, H.: 3,4-Dihydroxystyrene, a novel microbial inhibitor for phenylalanine hydroxylase and other pteridine-dependent monooxygenases. Biochim. Biophys. Acta, 789, 111–118 (1984)
Fujisawa, H.; Nakata, H.: Tryptophan 5-monooxygenase from rat brain stem. Methods Enzymol, 142, 83–87 (1987)
Hasegawa, H.; Ichiyama, A.: Tryptophan 5-monooxygenase from mouse mastocytoma: high-performance liquid chromatography assay. Methods Enzymol., 142, 88–92 (1987)
Fujisawa, H.; Nakata, H.: Tryptophan 5-monooxygenase from mouse mastocytoma clone P815. Methods Enzymol., 142, 93–96 (1987)
Nakata, H.; Fujisawa, H.: Simple and rapid purification of tryptophan 5-monooxygenase from rabbit brain by affinity chromatography. J. Biochem., 90, 567–569 (1981)
Nukiwa, T.; Tohyama, C.; Okita, C.; Kataoka, T.; Ichiyama, A.: Purification and some properties of bovine pineal tryptophan 5-monooxygenase. Biochem. Biophys. Res. Commun., 60, 1029–1035 (1974)
Nakata, H.; Fujisawa, H.: Tryptophan 5-monooxygenase from mouse mastocytoma P815. A simple purification and general properties. Eur. J. Biochem., 124, 595–601 (1982)
Nakata, H.; Fujisawa, H.: Purification and properties of tryptophan 5-monooxygenase from rat brain-stem. Eur. J. Biochem., 122, 41–47 (1982)
Cash, C.D.; Vayer, P.; Mandel, P.; Maitre, M.: Tryptophan 5-hydroxylase. Rapid purification from whole rat brain and production of a specific antiserum. Eur. J. Biochem., 149, 239–245 (1985)
Hosoda, S.; Nakamura, W.; Takatsuki, K.: Properties of tryptophan hydroxylase from human carcinoid tumor. Biochim. Biophys. Acta, 482, 27–34 (1977)
Friedman, P.A.; Kappelman, A.H.; Kaufman, S.: Partial purification and characterization of tryptophan hydroxylase from rabbit hindbrain. J. Biol. Chem., 247, 4165–4173 (1972)
Ichiyama, A.; Nakamura, S.; Nishizuka, Y.; Hayaishi, O.: Enzymic studies on the biosynthesis of serotonin in mammalian brain. J. Biol. Chem., 245, 1699–1709 (1970)
Joh, T.H.; Shikimi, T.; Pickel, V.M.; Reis, D.J.: Brain tryptophan hydroxylase: purification of, production of antibodies to, and cellular and ultrastructural localization in serotonergic neurons of rat midbrain. Proc. Natl. Acad. Sci. USA, 72, 3575–3579 (1975)
Tong, J.H.; Kaufman, S.: Tryptophan hydroxylase. Purification and some properties of the enzyme from rabbit hindbrain. J. Biol. Chem., 250, 4152–4158 (1975)
Naoi, M.; Maruyama, W.; Takahashi, T.; Ota, M.; Parvez, H.: Inhibition of tryptophan hydroxylase by dopamine and the precursor amino acids. Biochem. Pharmacol., 48, 207–211 (1994)
Park, D.H.; Stone, D.M.; Kim, K.S.; Joh, T.H.: Characterization of recombinant mouse tryptophan hydroxylase expressed in Escherichia coli. Mol. Cell. Neurosci., 5, 87–93 (1994)
Nagai, T.; Hamada, M.; Kai, N.; Tanoue, Y.; Nagayama, F.: Characterization of yellowfin tuna (Thunnus albacares, Scombroidei) tryptophan hydroxylase. Comp. Biochem. Physiol. B, 116, 161–165 (1997)
Moran, G.R.; Daubner, S.C.; Fitzpatrick, P.F.: Expression and characterization of the catalytic core of tryptophan hydroxylase. J. Biol. Chem., 273, 12259–12266 (1998)
Hamdan, F.F.; Ribeiro, P.: Characterization of a stable form of tryptophan hydroxylase from the human parasite Schistosoma mansoni. J. Biol. Chem., 274, 21746–21754 (1999)
Moran, G.R.; Phillips, R.S.; Fitzpatrick, P.F.: Influence of steric bulk and electrostatics on the hydroxylation regiospecificity of tryptophan hydroxylase: characterization of methyltryptophans and azatryptophans as substrates. Biochemistry, 38, 16283–16289 (1999)
Kowlessur, D.; Kaufman, S.: Cloning and expression of recombinant human pineal tryptophan hydroxylase in Escherichia coli: purification and characterization of the cloned enzyme. Biochim. Biophys. Acta, 1434, 317–330 (1999)
McKinney, J.; Teigen, K.; Froystein, N.A.; Salauen, C.; Knappskog, P.M.; Haavik, J.; Martinez, A.: Conformation of the substrate and pterin cofactor bound to human tryptophan hydroxylase. Important role of Phe313 in substrate specificity. Biochemistry, 40, 15591–15601 (2001)
Martinez, A.; Knappskog, P.M.; Haavik, J.: A structural approach into human tryptophan hydroxylase and its implications for the regulation of serotonin biosynthesis. Curr. Med. Chem., 8, 1077–1091 (2001)
Yohrling, L.G.; Jiang, G.C.; DeJohn, M.M.; Robertson, D.J.; Vrana, K.E.; Cha, J.H.: Inhibition of tryptophan hydroxylase activity and decreased 5-HT1A receptor binding in a mouse model of Huntington’s disease. J. Neurochem., 82, 1416–1423 (2002)
Daubner, S.C.; Moran, G.R.; Fitzpatrick, P.F.: Role of tryptophan hydroxylase Phe313 in determining substrate specificity. Biochem. Biophys. Res. Commun., 292, 639–641 (2002)
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2006 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
(2006). Tryptophan 5-monooxygenase. In: Schomburg, D., Schomburg, I. (eds) Springer Handbook of Enzymes. Springer Handbook of Enzymes, vol 27. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-30439-8_11
Download citation
DOI: https://doi.org/10.1007/3-540-30439-8_11
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-26583-2
Online ISBN: 978-3-540-30439-5
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)