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Compartmentalized Activation of Immune Cells During Sepsis and Organ Dysfunction

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Mechanisms of Sepsis-Induced Organ Dysfunction and Recovery

Part of the book series: Update in Intensive Care and Emergency Medicine ((UICMSOFT,volume 44))

Conclusion

Compartmentalization of the inflammatory response is a key feature of sepsis and SIRS. Tissue injury can be initiated far away from a distant insult. Blood borne elements are supposed to prevent initiation of deleterious inflammatory response within tissues. However, other circulating elements contribute to the ignition of inflammation at remote sites.

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Authors and Affiliations

  1. UP Cytokines & Inflammation, Institut Pasteur, 28 rue Dr Roux, 75015, Paris, France

    J. -M. Cavaillon & M. Adib-Conquy

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  1. J. -M. Cavaillon
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  2. M. Adib-Conquy
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Editors and Affiliations

  1. Health Sciences Center, Division Pulmonary & Critical Care Medicine, University of Colorado, E. Ninth Avenue 4200, 80262, Denver, CO, USA

    Edward Abraham MD

  2. Bloomsbury Institute of Intensive Care, Division Medicine, University College Hospital, Gower Street, WC1E 6BT, London, UK

    Mervyn Singer MD

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Cavaillon, J.M., Adib-Conquy, M. (2007). Compartmentalized Activation of Immune Cells During Sepsis and Organ Dysfunction. In: Abraham, E., Singer, M. (eds) Mechanisms of Sepsis-Induced Organ Dysfunction and Recovery. Update in Intensive Care and Emergency Medicine, vol 44. Springer, Berlin, Heidelberg . https://doi.org/10.1007/3-540-30328-6_11

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  • DOI: https://doi.org/10.1007/3-540-30328-6_11

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  • Print ISBN: 978-3-540-30157-8

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