Skip to main content

Autoimmune hepatitis

  • Chapter
  • 1530 Accesses

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   149.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Amberg, S.: Hyperproteinemia associated with severe liver damage. Proc. Mayo Clin. 1942; 17: 360–362

    Google Scholar 

  2. Bearn, A.G., Kunkel, H.G., Slater, R.J.: The problem of chronic liver disease in young women. Amer. J. Med. 1956; 21: 3–15

    CAS  PubMed  Google Scholar 

  3. Bellary, S., Schiano, T., Hartman, G., Black, M.: Chronic hepatitis with combined features of autoimmune chronic hepatitis and chronic hepatitis C: favorable response to prednisone and azathioprine. Ann. Intern. Med. 1995; 123: 32–34

    CAS  PubMed  Google Scholar 

  4. Berg, P.A., Stechemesser, E., Strienz, J.: Hypergammaglobulinämische chronische aktive Hepatitis mit Nachweis von Leber-Pankreas-spezifischen komplementbindenden Antikörpern. Verh. Dtsch. Ges. Inn. Med. 1981; 87: 921–927

    Google Scholar 

  5. Berg, P.A., Klein, R.: Autoimmune hepatitis and overlap syndrome: clinical and serological diagnosis. Praxis 2002; 91: 1339–1346

    CAS  PubMed  Google Scholar 

  6. Bianchi, F.B., Muratori, P., Muratori, L.: New antibodies and autoantigens in autoimmune hepatitis. Clin. Liver Dis. 2002; 6: 497–509

    Google Scholar 

  7. Boberg, K.M.: Prevalence and epidemiology of autoimmune hepatitis. Clin. Liver Dis. 2002; 6: 347–359

    Google Scholar 

  8. Brunt, E.M., di Bisceglie, A.M.: Histological changes after the use of mycophenolate mofetil in autoimmune hepatitis. Hum. Path. 2004; 35: 509–512

    CAS  PubMed  Google Scholar 

  9. Buchel, E., van Steenbergen, W., Nevens, F., Fevery, J.: Improvement of autoimmune hepatitis during pregnancy followed by flare-up after delivery. Amer. J. Gastroenterol. 2002; 97: 3160–3165

    Google Scholar 

  10. Burak, K.W., Urbanski, S.J., Swain, M.G.: Successful treatment of refractory type 1 autoimmune hepatitis with methotrexate. J. Hepatol. 1998; 29: 990–993

    Article  CAS  PubMed  Google Scholar 

  11. Carpenter, H.A., Czaya, A.J.: The role of histologic evaluation in the diagnosis and management of autoimmune hepatitis and its variants. Clin. Liver Dis. 2002; 6: 685–705

    PubMed  Google Scholar 

  12. Cattan, P., Bemey, T., Conti, F., Calmus, Y., Homberg, J.C., Houssin, D., Soubrane, O.: Outcome of orthotopic liver transplantation in autoimmune hepatitis according to subtypes. Transpl. Intl. 2002; 15: 34–38

    Google Scholar 

  13. Cianciara, J., Laskus, T.: Development of transient autoimmune hepatitis during interferon treatment of chronic hepatitis B. Dig. Dis. Sci. 1995; 40: 1842–1844

    Article  CAS  PubMed  Google Scholar 

  14. Coverdale, S.A., Field, J., Farrell, G.C.: How reversible is hepatic functional impairment in autoimmune hepatitis? J. Gastroenterol. Hepatol. 2003; 18: 371–375

    Article  CAS  PubMed  Google Scholar 

  15. Czaja, A.J., Wang, K.K., Shiels, M.T., Katzmann, J.H.: Oral pulse prednisone therapy after relapse of severe autoimmune chronic active hepatitis. J. Hepatol. 1993; 17: 180–186

    Article  CAS  PubMed  Google Scholar 

  16. Czaja, A.J., Carpenter, H.A., Santrach, P.J., Moore, S.B.: Significance of HLA DR4 in type 1 autoimmune hepatitis. Gastroenterology 1993; 105: 1502–1507

    CAS  PubMed  Google Scholar 

  17. Czaja, A.J., Cassani, F., Cataleta, M., Valentini, P., Bianchi, F.B.: Frequency and significance of antibodies to actin in type 1 autoimmune hepatitis. Hepatology 1996; 24: 1068–1073

    CAS  PubMed  Google Scholar 

  18. Czaja, A.J.: Treatment strategies in autoimmune hepatitis. Clin. Liver dis. 2002; 6: 799–824

    PubMed  Google Scholar 

  19. Czaja, A.J., Carpenter, H.A.: Decreased fibrosis during corticosteroid therapy of autoimmune hepatitis. J. Hepatol. 2004; 40: 646–652

    Article  CAS  PubMed  Google Scholar 

  20. Dalekos, G.N., Zachou, K., Liasko, C., Gatselis, N.: Autoantibodies and defined target autoantigens in autoimmune hepatitis: an overview. Eur. J. Int. Med. 2002; 13: 293–303

    CAS  Google Scholar 

  21. Danielsson, A., Prytz, H.: Oral budesonide for treatment of autoimmune chronic active hepatitis. Aliment. Pharmacol. Ther. 1994; 8: 585–590

    CAS  PubMed  Google Scholar 

  22. Devlin, J., Donaldson, P., Portmann, B., Heaton, N., Tan, K.-C., Williams, R.: Recurrence of autoimmune hepatitis following liver transplantation. Liver Transplant. Surg. 1995; 1: 162–165

    Article  CAS  Google Scholar 

  23. Dienes, H.P., Autschbach, F., Gerber, M.A.: Ultrastructural lesions in autoimmune hepatitis and steps of the immune response in liver tissue. Semin. Liver Dis. 1991; 11: 197–204

    CAS  PubMed  Google Scholar 

  24. Donaldson, P.T., Doherty, D.G., Hayllar, K.M., McFarlane, I.G., Johnson, P.J., Williams, R.: Susceptibility to autoimmune chronic active hepatitis: human leukocyte antigens DR4 and A1-B8-DR3 are independent risk factors. Hepatology 1991; 13: 701–706

    CAS  PubMed  Google Scholar 

  25. Donaldson, P.T.: Genetics in autoimmune hepatitis. Semin. Liver Dis. 2002; 22: 353–364

    Article  CAS  PubMed  Google Scholar 

  26. Duchini, A., McHutchison, J.G., Pockros, P.J.: LKM-positive autoimmune hepatitis in the western United States: a case series. Amer. J. Gastroenterol. 2000; 95: 3238–3241

    CAS  Google Scholar 

  27. Duclos-Vallée, J.-C., Sebagh, M., Rifai, K., Johanet, C., Ballot, E., Guettier, C., Karam, V., Hurtova, M., Feray, C., Reynes, M., Bismuth, H., Samuel, D.: A 10 year follow-up study of patients transplanted for autoimmune hepatitis: histological recurrence precedes clinical and biochemical recurrence. Gut 2003; 52: 893–897

    PubMed  Google Scholar 

  28. Dufour, J.-F., DeLellis, R., Kaplan, M.M.: Reversibility of hepatic fibrosis in autoimmune hepatitis. Ann. Intern. Med. 1997; 127: 981–985

    CAS  PubMed  Google Scholar 

  29. Dufour, J.F., Zimmermann, M., Reichen, J.: Severe autoimmune hepatitis in patients with previous spontaneous recovery of a flare. J. Hepatol. 2002; 37: 748–752

    Article  PubMed  Google Scholar 

  30. Fernandes, N.F., Redeker, A.G., Vierling, J.M., Villamil, F.G., Fong, T.L.: Cyclosporine therapy in patients with steroid resistant autoimmune hepatitis. Amer. J. Gastroenterol. 1999; 94: 241–248

    CAS  Google Scholar 

  31. Fried, M.W., Draguesku, J.O., Shindo, M., Simpson, L.H., Banks, S.M., Hoofnagle, J.H., Di Bisceglie, A.M.: Clinical and serological differentiation of autoimmune and hepatitis C virus-related chronic hepatitis. Dig. Dis. Sci. 1993; 38: 631–636

    Article  CAS  PubMed  Google Scholar 

  32. Garcia-Buey, L., Garcia-Monzon, C., Rodriguez, S., Borque, M.J., Gar-cia-Sanchez, A., Iglesias, R., de Castro, M., Mateos, F.G., Vicario, J.L., Balas, A., Moreno-Otero, R.: Latent autoimmune hepatitis triggered during interferon therapy in patients with chronic hepatitis C. Gastroenterology 1995; 108: 1770–1777

    CAS  PubMed  Google Scholar 

  33. Goldstein, N.S., Bayati, N., Silverman, A.L., Gordon, S.C.: Minocycline as a cause of drug-induced autoimmune hepatitis. — Report of four cases and comparison with autoimmune hepatitis. Amer. J. Clin. Path. 2000; 114: 591–598

    CAS  Google Scholar 

  34. Gregorio, G.V., Portmann, B., Reid, F., Donaldson, P.T., Doherty, D.G., McCartney, M., Mowat, A.P., Vergani, D., Mieli-Vergani, G.: Autoimmune hepatitis in childhood: a 20-year experience. Hepatology 1997

    Google Scholar 

  35. Han, S., Tredger, M., Gregorio, G.V., Mieli-Vergani, G., Vergani, D.: Anti-liver cytosolic antigen type 1 (LC1) antibodies in childhood autoimmune liver disease. Hepatology 1995; 21: 58–62

    Article  CAS  PubMed  Google Scholar 

  36. Herzog, D., Rasquin-Weber, A.-M., Debray, D., Alvarez, F.: Subfulminant hepatic failure in autoimmune hepatitis type 1: an unusual form of presentation. J. Hepatol. 1997; 27: 578–582

    Article  CAS  PubMed  Google Scholar 

  37. Hodges, S., Lobo-Yeo, A., Donaldson, P., Tanner, M.S., Vergani, D.: Autoimmune chronic active hepatitis in a family. Gut 1991; 32: 299–302

    CAS  PubMed  Google Scholar 

  38. Homberg, J.-C., Abuaf, N., Bernard, O., Islam, S., Alvarez, F., Khalil, S.H., Poupon, R., Darnis, F., Lévy, V.-G., Grippon, P., Opolon, P., Bernuau, J., Benhamou, J.-P., Alagille, D.: Chronic active hepatitis associated with anti-liver/kidney microsome antibody type 1: a second type of “autoimmune hepatitis”. Hepatology 1987; 7: 1333–1339

    CAS  PubMed  Google Scholar 

  39. Hunziker, L., Recher, M., Andrew, J., Macpherson, A.J., Ciura, A., Freigang, S., Hengartner, H., Zinkernagel, R.M.: Hypergammaglobulinemia and autoantibody induction mechanisms in viral infection. Nat. Immunol. 2003; 4: 343–349

    CAS  PubMed  Google Scholar 

  40. Jackson, L.D., Song, E.: Cyclosporine in the treatment of corticoidresistant autoimmune chronic active hepatitis. Gut 1995; 36: 459–461

    CAS  PubMed  Google Scholar 

  41. Johnson, P.J., McFarlane, I.G., Eddleston, A.L.W.F.: The natural course and heterogeneity of autoimmune-type chronic active hepatitis. Semin. Liver Dis. 1991; 11: 187–196

    CAS  PubMed  Google Scholar 

  42. Johnson, P.J., McFarlane, I.G., Williams, R.: Azathioprine for longterm maintenance of remission in autoimmune hepatitis. New Engl. J. Med. 1995; 333: 958–963

    Article  CAS  PubMed  Google Scholar 

  43. Joske, R.A., King, W.E.: The L. E. cell phenomen in active viral hepatitis. Lancet 1955/II: 477–480

    Google Scholar 

  44. Kanzler, S., Gerken, G., Dienes, H.P., Meyer zum Büschenfelde, K.H., Lohse, A.W.: Cyclophosphamide as alternative immunosuppressive therapy for autoimmune hepatitis-report of three cases. Zschr. Gastroenterol. 1997; 35: 571–578

    CAS  Google Scholar 

  45. Klein, C., Philipp, T., Greiner, P., Strobelt, M., Müller, H., Trautwein, C., Brandis, M., Manns, M.: Asymptomatic autoimmune hepatitis associated with anti-LC-1 autoantibodies. J. Pediatr. Gastroenterol. Nutrit. 1996; 23: 461–465

    CAS  Google Scholar 

  46. Kogan, J., Safadi, R., Ashur, Y., Shouval, D., Ilan, Y.: Prognosis of symptomatic versus asymptomatic autoimmune hepatitis: a study of 68 patients. J. Clin. Gastroenterol. 2002; 35: 75–81

    Article  PubMed  Google Scholar 

  47. Kunkel, H.G., Ahrens, E.H., Eisenmenger, W.J., Bougiovanni, A.M., Slater, R.J.: Extreme hypergammaglobulinemia in young women with liver disease of unknown etiology. J. Clin. Invest. 1951; 30: 654–659

    Google Scholar 

  48. Lohse, A.W., Gerken, G., Mohr, H., Löhr, H.F., Treichel, U., Dienes, H.P., Meyer zum Büschenfelde, K.-H.: Relation between autoimmune liver diseases and viral hepatitis. Clinical and serological characteristics in 859 patients. Z. Gastroenterol. 1995; 33: 527–533

    CAS  PubMed  Google Scholar 

  49. Mackay, I.R., Taft, L.I., Cowling, D.C.: Lupoid hepatitis. Lancet 1956/II: 1323–1326

    Google Scholar 

  50. Manabe, K., Donaldson, P.T., Underhill, J.A., Doherty, D.G., Mieli-Ver-gani, G., McFarlane, I.G., Eddleston, A.L., Williams, R.: Human leukocyte antigen A1-B8-DR3-DQ2-DPB1-0401 extended haplotype in autoimmune hepatitis. Hepatology 1993; 18: 1334–1337

    CAS  PubMed  Google Scholar 

  51. Manns, M., Gerken, G., Kyriatsoulis, A., Staritz, M., Meyer zum Büschenfelde, K.-H.: Characterisation of a new subgroup of autoimmune chronic active hepatitis by autoantibodies against a soluble liver antigen. Lancet 1987/I: 292–294

    Google Scholar 

  52. McFarlane, I.G.: Definition and classification of autoimmune hepatitis. Semin. Liver Dis. 2002; 22: 317–324

    Article  PubMed  Google Scholar 

  53. Medina, J., Garcia-Buey, L., Moreno-Otera, R.: Immunopathogenetic and therapeutic aspects of autoimmune hepatitis (review). Amer. Pharm. Ther. 2003; 17: 1–16

    CAS  Google Scholar 

  54. Meyer zum Büschenfelde, K.H.: Autoimmune hepatitis: “Hepatitis sui generic”. J. Hepatol. 2003; 38: 130–135

    Google Scholar 

  55. Michel, G., Ritter, A., Gerken, G., Meyer zum Büschenfelde, K.-H., Decker, R., Manns, M.P.: Anti-GOR and hepatitis C virus in autoimmune liver diseases. Lancet 1992; 339: 267–269

    Article  CAS  PubMed  Google Scholar 

  56. Mieli-Vergani, G., Vergani, D.: Autoimmune hepatitis in children. Clin. Liver Dis. 2002; 6: 247–259

    Google Scholar 

  57. Milkiewicz, P., Hubscher, S.G., Skiba, G., Hathaway, M., Elias, E.: Recurrence of autoimmune hepatitis after liver transplantation. Transplantation 1999; 68: 253–256

    CAS  PubMed  Google Scholar 

  58. Misdraji, J., Thiim, M., Graeme-Cook, F.M.: Autoimmune hepatitis with centrilobular necrosis. Amer. J. Surg. Path. 2003; 28: 471–478

    Google Scholar 

  59. Mistilis, S.P., Vickers, C.R., Darroch, M.H., McCarthy, S.W.: Cyclosporine, a new treatment for autoimmune chronic active hepatitis. Med. J. Austr. 1985; 143: 463–465

    CAS  Google Scholar 

  60. Muratori, L., Lenzi, M., Cataleta, M., Giostra, F., Cassani, F., Ballardini, G., Zauli, D., Bianchi, F.B.: Interferon therapy in liver/kidney microsomal antibody type 1-positive patients with chronic hepatitis C. J. Hepatol. 1994; 21: 199–203

    Article  CAS  PubMed  Google Scholar 

  61. Nakadate, I., Nakamura, A., Endo, R., Iwai, M., Kaneta, H., Shimotono, H., Sasaki, S., Takikawa, Y., Yamazaki, K., Madarame, T., Kashiwabara, T., Suzuki, K., Sato, S.: Autoimmune hepatitis presenting with acute hepatic failure. Acta Hepatol. Japan. 1993; 34: 665–671

    Google Scholar 

  62. Neuberger, J., Portmann, B., Calne, R., Williams, R.: Recurrence of autoimmune chronic active hepatitis following orthotopic liver grafting. Transplantation 1984; 37: 363–365

    CAS  PubMed  Google Scholar 

  63. Nobili, V., Comparcola, D., Sartorelli, M.R., Devito, R., Marcellini, M.: Autoimmune hepatitis type 1 after Epstein-Barr virus infection. Paediatr. Infect. J. 2003; 22: 387

    Google Scholar 

  64. Nouri-Aria, K.T., Donaldson, P.T., Hegarty, J.E., Eddleston, A.L.W.F., Williams, R.: HLA-A1-B8-DR3 and suppressor cell function in first 688 degree relatives of patients with autoimmune chronic active hepatitis. J. Hepatol. 1985; 1: 235–241

    CAS  PubMed  Google Scholar 

  65. Obermayer-Straub, P., Strassburg, C.P., Manns, M.P.: Autoimmune hepatitis. J. Hepatol. 2000; 32(Suppl. 1) 181–197

    CAS  PubMed  Google Scholar 

  66. Papo, T., Marcellin, P., Bernuau, J., Durand, F., Poynard, T., Benhamou, J.P.: Autoimmune chronic hepatitis exacerbated by alphainterferon. Ann. Intern. Med. 1992; 116: 51–53

    CAS  PubMed  Google Scholar 

  67. Park, S.Z., Nagorney, D.M., Czaja, A.J.: Hepatocellular carcinoma in autoimmune hepatitis. Dig. Dis. Sci. 2000; 45: 1944–1948

    Article  CAS  PubMed  Google Scholar 

  68. Paroli, M., Franco, A., Santilio, I., Balsano, C., Levrero, M., Barnaba, V.: Cyclosporine A in the treatment of autoimmune chronic active hepatitis occurring with or without circulating antibodies against hepatitis C Virus. Int. J. Immunther. 1992; 8: 135–140

    Google Scholar 

  69. Perdigoto, R., Carpenter, H.A., Czaja, A.J.: Frequency and significance of chronic ulcerative colitis in severe corticosteroid-treated autoimmune hepatitis. J. Hepatol. 1992; 14: 325–331

    Article  CAS  PubMed  Google Scholar 

  70. Person, J.L., McHutchison, J.G., Fong, T., Redeker, A.G.: A case of cyclosporine-sensitive, steroid-resistant autoimmune chronic active hepatitis. J. Clin. Gastroent. 1993; 17: 317–320

    CAS  PubMed  Google Scholar 

  71. Pratt, D.S., Flavin, D.P., Kaplan, M.M.: The successful treatment of autoimmune hepatitis with 6-mercaptopurine after failure with azathioprine. Gastroenterology 1996; 110: 271–274

    Article  CAS  PubMed  Google Scholar 

  72. Rahaman, S.M., Chira, P., Koff, R.S.: Idiopathic autoimmune chronic hepatitis triggered by hepatitis A. Amer. J. Gastroent. 1994; 89: 106–108

    CAS  PubMed  Google Scholar 

  73. Rambusch, E.G., Manns, M.P.: Immunsuppressive Therapie der autoimmunen Lebererkrankungen. Internist 1997; 38: 574–581

    Article  CAS  PubMed  Google Scholar 

  74. Rehermann, B., Michitaka, K., Durazzo, M., Mergener, K., Velev, P., Manns, M.P.: Viruses and auto-immune hepatitis. Europ. J. Clin. Invest. 1994; 24: 11–19

    CAS  PubMed  Google Scholar 

  75. Reich, D.J., Fiel, I., Guarrera, J.V., Emre, S., Schwartz, M.E., Miller, C.M., Sheiner, P.A.: Liver transplantation for autoimmune hepatitis. Hepatology 2000; 32: 693–700

    Article  CAS  PubMed  Google Scholar 

  76. Richardson, P.D., James, P.D., Ryder, S.D.: Mycophenolate mofetil for maintenance of remission in autoimmune hepatitis in patients resistant. J. Hepatol. 2000; 33: 371–375

    Article  CAS  PubMed  Google Scholar 

  77. Robertson, D.A.F., Zhang, S.L., Guy, E.C., Wright, R.: Persistent measles virus genome in autoimmune chronic active hepatitis. Lancet 1987/I: 9–11

    Google Scholar 

  78. Ruiz-Mureno, M., Rua, M.J., Carreno, V., Quironga, J.A., Manns, M., Meyer zum Büschenfelde, K.-H.: Autoimmune chronic active hepatitis type 2 manifested during interferon therapy in children. J. Hepatol. 1991; 12: 265–266

    Google Scholar 

  79. Ryder, S.D., Koskinas, J., Rizzi, P.M., McFarlane, I.G., Portmann, B.C., Naoumov, N.V., Williams, R.: Hepatocellular carcinoma complicating autoimmune hepatitis: role of hepatitis C virus. Hepatology 1995; 22: 718–722

    Article  CAS  PubMed  Google Scholar 

  80. Sanchez-Urdazpal, L., Czaja, A.J., von Hoek, B., Ruud, A.F., Krom and Russel, H., Wiesner, J.: Prognostic features and role of liver transplantation in severe corticosteroid-treated autoimmune chronic active hepatitis. Hepatology 1991; 15: 215–221

    Google Scholar 

  81. Seki, T., Kiyosawa, K., Inoko, H., Ota, M.: Association of autoimmune hepatitis with HLA-Bw54 and DR4. Hepatology 1990; 12: 1300–1304

    CAS  PubMed  Google Scholar 

  82. Sherman, K.E., Narkewicz, M., Pinto, P.C.: Cyclosporine in the management of corticosteroid-resistant type I autoimmune chronic active hepatitis. J. Hepatol. 1994; 21: 1040–1047

    Article  CAS  PubMed  Google Scholar 

  83. Singh, R., Nair, S., Farr, G., Mason, A., Perrillo, R.P.: Acute autoimmune hepatitis presenting with centrizonal liver disease: case report and review of the literature. Amer. J. Gastroenterol. 2002; 97: 2670–2673

    Google Scholar 

  84. Stechemesser, E., Klein, R., Berg, P.A.: Characterization and clinical relevance of liver-pancreas antibodies in autoimmune hepatitis. Hepatology 1993; 18: 1–9

    Article  CAS  PubMed  Google Scholar 

  85. Stellon, A.J., Kreating, J.J., Johnson, P.J., McFarlane, I.G., Williams, R.: Maintenance of remission in autoimmune chronic active hepatitis with azathioprine after corticosteroid withdrawal. Hepatology 1988; 8: 781–784

    CAS  PubMed  Google Scholar 

  86. Storch, W.B.: New autoantibodies and their antigens in autoimmune diseases. Cell. Molec. Biol. 1997; 43: 337–344 · Autoantikörper und ihre diagnostische Bedeutung. Dtsch. Med. Wschr. 1998; 123: 1213–1216

    CAS  Google Scholar 

  87. Storch, W.B.: Autoimmune hepatitis — update dy2004. Cell. Mol. Biol. 2004; 50: 569–580

    Google Scholar 

  88. Strassburg, C.P., Manns, M.P.: Autoantibodies and autoantigens in autoimmune hepatitis. Semin. Liver Dis. 2002; 22: 339–352

    Article  CAS  PubMed  Google Scholar 

  89. Tagle Arrospide, M., Leon Barva, R.: Viral hepatitis A as triggering agent of autoimmune hepatitis. Report of case and review of the literature. Rev. Gastroenterol. Peru 2003; 23: 134–137

    PubMed  Google Scholar 

  90. Terracciano, L.M., Patzina, R.A., Lehmann, F.S., Tornillo, L., Cathomas, G., Mhawech, P., Vecchione, R.; Bianchi, L.: A spectrum of histopathologic findings in autoimmune liver disease. Amer. J. Clin. Pathol. 2000; 114: 705–711

    CAS  Google Scholar 

  91. Todros, L., Saracco, G., Durazzo, M., Abate, M.L., Touscoz, G., Scaglione, L., Verme, G., Rizetto, M.: Efficacy and safety of interferon alfa therapy in chronic hepatitis C with autoantibodies to liver-kidney microsomes. Hepatology 1995; 22: 1374–1378

    Article  CAS  PubMed  Google Scholar 

  92. Treichel, U., Gerken, G., Rossol, S., Rotthauwe, H.W., Meyer zum Büschenfelde, K.-H., Poralla, T.: Autoantibodies against the human asialoglycoprotein receptor: effects of therapy in autoimmune and virus induced chronic active hepatitis. J. Hepatol. 1993; 19: 55–63

    Article  CAS  PubMed  Google Scholar 

  93. Van den Berg, A.P.: Autoimmune hepatitis: pathogenesis, diagnosis and treatment. Scand. J. Gastroenterol. 1998; 33(Suppl. 225): 66–69

    Google Scholar 

  94. Van Thiel, D.H., Wright, H., Carroll, P., Abu-Elmagd, K., Rodriguez, Rilo, H., McMichael, J., Irish, W., Starzl T.E.: Tacrolimus: a potential new treatment for autoimmune chronic active hepatitis: results of an open-label preliminary trial. Amer. J. Gastroenterol. 1995; 90: 771–776

    Google Scholar 

  95. Vento, S., Garofano, T., di Perri, G., Dolci, L., Concia, E., Bassetti, D.: Identification of hepatitis A virus as trigger for autoimmune chronic hepatitis type 1 in susceptible individuals. Lancet 1991; 337: 1183–1187

    Article  CAS  PubMed  Google Scholar 

  96. Vento, S., Guella, L., Mirandola, F., Cainelli, F., di Perri, G., Solbiati, M., Ferraro, T., Concia, E.: Epstein-Barr virus as a trigger for autoimmune hepatitis in susceptible individuals. Lancet 1995; 346: 608–609

    Article  CAS  PubMed  Google Scholar 

  97. Vento, S., Cainelli, F., Ferraro, T., Concia, E.: Autoimmune hepatitis type 1 after measles. Amer. J. Gastroenterol. 1996; 91: 2618–2620

    CAS  Google Scholar 

  98. Vergani, D., Mieli-Vergani, G.: Autoimmune hepatitis. Autoimmun. Rev. 2003; 2: 241–247

    Article  CAS  PubMed  Google Scholar 

  99. Vogel, A., Strassburg, C.P., Manns, M.P.: 77C/G mutation in the tyrosine phosphatase CD45 gene and autoimmune hepatitis: evidence for a genetic link. Genes Immun. 2003; 4: 79–81

    Article  CAS  PubMed  Google Scholar 

  100. Wächter, B., Kyriatsouis, A., Lohse, A.W., Gerken, G., Meyer zum Büschenfelde, K.-H., Manns, M.P.: Characterisation of liver cytokeratin as a major target of anti-SLA antibodies. J. Hepatol. 1990; 11: 232–239

    PubMed  Google Scholar 

  101. Waldenström, J.: Leber, Blutproteine und Nahrungseiweiß. Dtsch. J. Verdau. Stoffwechselkr. 1950; 15: 113–119

    Google Scholar 

  102. Wang, K.K., Czaja, A.J.: Hepatocellular carcinoma in corticosteroidtreated severe autoimmune chronic active hepatitis. Hepatology 1988

    Google Scholar 

  103. Wen, L., Peakman, M., Lobo-Yeo, A., McFarlane, B.M., Mowat, A.P., Mieli-Vergani, G., Vergani, D.: T-cell-directed hepatocyte damage in autoimmune chronic active hepatitis. Lancet 1990; 336: 1527–1530

    Article  CAS  PubMed  Google Scholar 

  104. Wies, I., Brunner, S., Henninger, J., Herkel, J., Kanzler, S., Meyer zum Büschenfelde, K.-H., Lohse, A.W.: Identification of target antigen for SLA/LP autoantibodies in autoimmune hepatitis. Lancet 2000; 355: 1510–1515

    Article  CAS  PubMed  Google Scholar 

  105. Wright, H.L., Bou-Abboud, C.F., Hassanein, T., Block, G.D., Demetris, A.J., Starzl, T.E., van Thiel, D.H.: Disease recurrence and rejection following liver transplantation for autoimmune chronic active liver disease. Transplantation 1992; 53: 136–139

    CAS  PubMed  Google Scholar 

  106. Yamaoka, K., Koizumi, K., Asahina, Y., Tajiri, K., Sakai, Y., Tazawa, J.: Hepatocellular carcinoma associated with autoimmune hepatitis — a case report and a review of the literature. Japan. J. Gastroenterol. 1994; 91: 1262–1267

    CAS  Google Scholar 

  107. Zanger, U.M., Hauri, H.P., Loeper, J., Homberg, J.C., Meyer, U.A.: Antibodies against human cytochrome P 450 db1 in autoimmune hepatitis type II. Proc. Nat. Acad. Sci. 1988; 27: 8256–8260

    Google Scholar 

Download references

Rights and permissions

Reprints and permissions

Copyright information

© 2006 Springer Medizin Verlag Heidelberg

About this chapter

Cite this chapter

(2006). Autoimmune hepatitis. In: Hepatology Principles and Practice. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-28977-1_33

Download citation

  • DOI: https://doi.org/10.1007/3-540-28977-1_33

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-28976-0

  • Online ISBN: 978-3-540-28977-7

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics