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Acute viral hepatitis

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References

The history of acute viral hepatitis

  1. Andersen, T.Th.: Untersuchungen über die Ätiologie der Hepatitis epidemica. (Dänisch) Ugeskr. Laeg. 1938: 777–778

    Google Scholar 

  2. Balayan, M.S., Andjaparidze, A.G., Savinskaya, S.S., Ketiladze, E.S., Braginsky, D.M., Savinov, A.P., Poleschuk, V.F.: Evidence for a virus in non-A, non-B hepatitis transmitted via the fecal-oral route. Intervirology 1983; 20: 23–31

    PubMed  CAS  Google Scholar 

  3. Blumberg, B.S., Alter, H.J., Visnich, S.: A “new” antigen in leukemia sera. J. Amer. Med. Ass. 1965; 191: 541–546

    CAS  Google Scholar 

  4. Bormann, von, F.: Hepatitis epidemica. Ergebn. Inn. Med. 1940; 58: 201–284

    Google Scholar 

  5. Choo, Q.L., Kuo, G., Weiner, A.J., Overby, L.R., Bradley, D.W., Houghton, M.: Isolation of a CDNA clone derived from a blood-orne Non-A, Non-B viral hepatitis genome. Science 1989; 244: 359–361

    PubMed  CAS  Google Scholar 

  6. Cockayne, E.A.: Catarrhal jaundice, sporadic and epidemic, and in relation to acute yellow atrophy of the liver. Quart. J. Med. 1912; 6: 1–29

    Google Scholar 

  7. Corelli, F.: Der Icterus catarrhalis als allergische Hepatitis. Die allergische Entzündung der Leber und der Gallenwege. Etiopathogenetisches Studium. Dtsch. Arch. Klin. Med. 1940; 185: 600–625

    Google Scholar 

  8. Dane, D.S., Cameron, C.H., Briggs, M.: Virus-like particles in serum of patients with Australia-antigen-associated hepatitis. Lancet 1970/I: 695–700

    Google Scholar 

  9. Feinstone, S.M., Kapikian, A.Z., Purcell, R.H.: Hepatitis A: detection by immune electron microscopy of a viruslike antigen associated with acute illness. Science 1973; 182: 1026–1028

    PubMed  CAS  Google Scholar 

  10. Feinstone, S.M., Kapikian, A.Z., Purcell, R.H., Alter, H.J., Holland, P.V.: Transfusion-associated hepatitis not due to viral hepatitis type A or B. New Engl. J. Med. 1975; 292: 767–770

    PubMed  CAS  Google Scholar 

  11. Fröhlich, C.: Ueber Icterusepidemien. Dtsch. Arch. Klin. Med. 1879; 24: 394–406

    Google Scholar 

  12. Gebhardt, F., Voegt, H.: Die verschiedenen Verlaufsformen der Hepatitis contagiosa. Dtsch. Med. Wschr. 1944; 70: 450–451

    Google Scholar 

  13. Havens, W.P.jr., Ward, R., Drill, V.A., Paul, J.R.: Experimental production of hepatitis by feeding icterogenic materials. Proc. Soc. Exp. Biol. Med. 1944; 57: 206–208

    CAS  Google Scholar 

  14. Herlitz, I.F.: De ictero speciatim epidemico Goettingae, grassante dissertatio Goettingae. Diss.-Inaug. 1761

    Google Scholar 

  15. Jehn: Eine Icterusepidemie in wahrscheinlichem Zusammenhang mit vorausgegangener Revaccination. Dtsch. Med. Wschr. 1885; 11: 354–356

    Google Scholar 

  16. Köhnhorn, C.: Ueber Gelbsucht-Epidemien. Berlin. Klin. Wschr. 1877: 89–90; 104–106; 132–134

    Google Scholar 

  17. Krugman, S., Giles, J.P., Hammond, J.: Infectious hepatitis. Evidence for two distinctive clinical, epidemiological, and immunological types of infection. J. Amer. Med. Ass. 1967; 200: 365–373

    CAS  Google Scholar 

  18. Lainer, F.: Zur Frage der Infektiosität des Ikterus. Wien. Klin. Wschr. 1940: 601–604

    Google Scholar 

  19. Linnen, J., Wages, J.jr., Zhang-Keck, Z.-Y., Fry, K.E., Krawczynski, K.Z., Alter, H., Koonin, E., Gallagher, M., Alter, M., Hadziyannis, St., Karayiannis, P. et al.: Molecular cloning and disease association of hepatitis G virus: a transfusion-transmissible agent. Science 1996; 271: 505–508

    PubMed  CAS  Google Scholar 

  20. Lürman: Eine Icterusepidemie. Berlin. Klin. Wschr. 1885; 22: 20–23

    Google Scholar 

  21. Martini, G.A.: Die homologe Serum-Hepatitis. Dtsch. Med. Wschr. 1949; 18: 568–572

    Google Scholar 

  22. McCallum, F.O., Bradley, W.H.: Transmission of infective hepatitis to human volunteers. Lancet 1944/II: 228.

    Google Scholar 

  23. Neefe, J.R., Stokes, J.jr., Reinhold, J.G.: Oral administration to volunteers of feces from patients with homologous serum hepatitis and infectious (epidemic) hepatitis. Amer. J. Med. Sci. 1945; 210: 29–32

    Google Scholar 

  24. Paul, J.R., Havens, W.P.jr., Sabin, A.B., Philipp, C.B.: Transmission experiments in serum jaundice and infectious hepatitis. J. Amer. Med. Ass. 1945; 128: 911–915

    Google Scholar 

  25. Prince, A.M.: An antigen detected in the blood during the incubation period of serum hepatitis. Proc. Nat. Acad. Sci. USA 1968; 60: 814–821

    PubMed  CAS  Google Scholar 

  26. Prince, A.M., Brotman, B., Grady, G.F., Kuhns, W.J., Hazzi, C., Levine, R.W., Millian, S.J.: Long-incubation post-transfusion hepatitis without serological evidence of exposure to hepatitis-B virus. Lancet 1974/II: 241–246

    Google Scholar 

  27. Purcell, R.H.: The discovery of the hepatitis viruses. Gastroenterology 1993; 104: 955–963

    PubMed  CAS  Google Scholar 

  28. Rizzetto, M., Canese, M.G., Arico, S., Crivelli, O., Trepo, C., Bonino, F., Verme, G.: Immunofluorescence detection of new antigen-antibody system (δ/anti-δ) associated to hepatitis B virus in liver and in serum of HBsAg carriers. Gut 1977; 18: 997–1003

    PubMed  CAS  Google Scholar 

  29. Virchow, R.: Über das Vorkommen und den Nachweis des hepatogenen, insbesondere des katarrhalischen Icterus. Virchow’s Archiv 1864; 32: 117–125

    Google Scholar 

  30. Voegt, H.: Zur Aetiologie der Hepatitis epidemica. Münch. Med. Wschr. 1942; 89: 76–79

    Google Scholar 

Morphological and aetiopathogenetic variety

  1. Bianchi, L., de Groote, J., Desmet, V.J., Gedigk, P., Korb, G., Popper, H., Poulsen, H., Scheuer, P.J., Schmid, M., Thaler, H., Wepler, W.: Morphological criteria in viral hepatitis. Lancet 1971/I: 333–337

    Google Scholar 

  2. Barak, N., Huminer, D., Segal, T., Ben Ari, Z., Halevy, J., Tur Kaspa, R.: Lipoamide dehydrogenase deficiency: a newly discovered cause of acute hepatitis in adults. J. Hepatol. 1998; 29: 482–484

    CrossRef  PubMed  CAS  Google Scholar 

  3. Fimmel, C.J., Guo, L., Compans, R.W., Brunt, E.M., Hickman, S., Perrillo, R.R., Mason, A.L.: A case of syncytial giant cell hepatitis with features of a paramyxoviral infection. Amer. J. Gastroenterol. 1998; 93: 1931–1937

    CAS  Google Scholar 

  4. Ishak, K.G.: Light microscopic morphology of viral hepatitis. Amer. J. Clin. Pathol. 1976; 65: 787–827

    Google Scholar 

  5. Kim, M.Y., Baik, S.K., Choi, Y.J., Park, D.H., Kim, H.S., Lee, D.K., Kwon, S.O.: Endoscopic sonographic evaluation of the thickened gallbladder wall in patients with acute hepatitis. J. Clin. Ultrasound 2003; 31: 245–249

    CrossRef  PubMed  Google Scholar 

  6. Phillips, M., Purcell, S.: Modern aspects of the morphology of viral hepatitis. Hum. Pathol. 1981; 12: 1060–1084

    PubMed  CAS  Google Scholar 

Acute viral hepatitis A

  1. Phillips, J.R., Angulo, P., Lindor, K.: Recurrent idiopathie hepatitis: a new entity? J. Clin. Gastroenterol. 2003; 37: 267–269

    PubMed  Google Scholar 

  2. Becker, B., Prömse, B., Krämer, J., Exner, M.: Transmission of human pathogenic viruses via food: bakery products causing hepatitis A in Germany. Gesundheitswesen 1996; 58: 339–340

    PubMed  CAS  Google Scholar 

  3. Black, M.M., Mann, N.P.: Gangrenous cholecystitis due to hepatitis A infection. J. Trop. Med. Hyg. 1992; 95: 73–74

    PubMed  CAS  Google Scholar 

  4. Bornstein, J.D., Byrd, D.E., Trotter, J.F.: Relapsing hepatitis A. A case report and review of the literature. J. Clin. Gastroenterol. 1999; 28: 355–359

    CrossRef  PubMed  CAS  Google Scholar 

  5. Bower, W.A., Nainan, O.V., Han, X., Margolis, H.S.: Duration of viremia in hepatitis A virus infection. J. Infect. Dis. 2000; 182: 12–17

    CrossRef  PubMed  CAS  Google Scholar 

  6. Breuer, G.S., Morali, G., Finkelstein, Y., Halevy, J.: A pregnant woman with hepatitis A and Guillain-Barré. J. Clin. Gastroenterol. 2001; 32: 179–180

    CrossRef  PubMed  CAS  Google Scholar 

  7. Chironna, M., Lopalco, P., Prato, R., Germinario, C., Barbuti, S., Quarto, M.: Outbreak of infection with hepatitis A virus (HAV) associated with a foodhandler and confirmed by sequence analysis reveals a new HAV genotype 1 B variant. J. Clin. Microbiol. 2004; 42: 2825–2828

    CrossRef  PubMed  CAS  Google Scholar 

  8. Cohen, O., Mevorach, D., Ackerman, Z., Oren, R.: Thrombocytopenic purpura as a manifestation of acute hepatitis A. J. Clin. Gastroenterol. 1993; 17: 166–167

    PubMed  CAS  Google Scholar 

  9. Conzelmann-Auer, C., Ackermann-Liebrich, U., Herzog, Ch., Bächlin, A.: An outbreak of hepatitis A in a kindergarden. Schweiz. Med. Wschr. 1992; 122: 1559–1566

    PubMed  CAS  Google Scholar 

  10. Corpechot, C., Cadranel, J.-F., Hoang, C., Assogba, U., Beaumont, J.-L., Rogeaux, O., Lunel, F., Opolon, P.: Hepatite virale A cholestatique de l’adulte. Etude clinique, biologique et histopathologique de 9 cas. Gastroenterol. Clin. Biol. 1994; 18: 743–750

    CAS  Google Scholar 

  11. Cotter, S.M., Sansom, S., Long, T., Koch, E., Kellerman, S., Smith, F., Averhoff, F., Bell, B.P.: Outbreak of hepatitis A among men who have sex with men: implications for hepatitis A vaccination strategies. J. Infect. Dis. 2003; 187: 1235–1240

    CrossRef  PubMed  Google Scholar 

  12. Dagan, R., Yaqupsky, P., Barki, Y.: Acute ascites accompanying hepatitis A infection in a child. Infection 1988; 16: 360–361

    CrossRef  PubMed  CAS  Google Scholar 

  13. Dan, M., Yaniv, R.: Cholestatic hepatitis, cutaneous vasculitis, and vascular deposits of immunoglobulin M and complement associated with hepatitis A virus infection. Amer. J. Med. 1990; 89: 103–104

    PubMed  CAS  Google Scholar 

  14. Davis, T.V., Keeffe, E.B.: Acute pancreatitis associated with acute hepatitis A. Amer. J. Gastroenterol. 1992; 87: 1648–1650

    CAS  Google Scholar 

  15. Deloince, R., Leveque, F., Crance, J.-M., Trepo, C.: Epidemiologie de l’hepatite virale A. Gastroenterol. Clin. Biol. 1994; 18: 354–361

    CAS  Google Scholar 

  16. Dentinger, C.M., Bower, W.A., Nainan, O.V., Cotter, S.M., Myers, G., Dubusky, L.M., Fowler, S., Salehi, E.D.P., Bell, B.P.: An outbreak of hepatitis A associated with green onions. J. Infect. Dis. 2001: 183: 1273–1276

    CrossRef  PubMed  CAS  Google Scholar 

  17. Durst, R.Y., Goldsmidt, N., Namestnick, J., Safadi, R., Ilan, Y.: Familial cluster of fulminant hepatitis A infection. J. Clin. Gastroenterol. 2001; 32: 453–454

    CrossRef  PubMed  CAS  Google Scholar 

  18. Enriquez, R., Frösner, G.G., Hochstein-Mintzel, V., Riedemann, St., Reinhardt, G.: Accumulation and persistence of hepatitis A virus in mussels. J. Med. Virol. 1992; 37: 174–179

    PubMed  CAS  Google Scholar 

  19. Fagan, E.A., Partridge, M., Sowray, J.H., Williams, R.: Review of the herpes-viruses and hepatitis A: the potential hazards in dental care. Oral Surg. Oral Med. Oral Pathol. 1987; 64: 693–696

    PubMed  CAS  Google Scholar 

  20. Forbes, A., Williams, R.: Changing epidemiology and clinical aspects of hepatitis A. Brit. Med. Bull. 1990; 46: 303–318

    PubMed  CAS  Google Scholar 

  21. Fröhlich, J., Zeller, I.: Risk of HAV infection with employees of a sewage plant cooperative society. Arbeitsmed. Sozialmed. Präventivmed. 1993; 28: 503–505

    Google Scholar 

  22. Fujiyama, S., Iino, S., Odoh, K., Kuzuhara, S., Watanabe, H., Tanaka, M., Mizuno, K., Sato, T.: Time course of hepatitis A virus antibody titer after active and passive immunization. Hepatology 1992; 15: 983–988

    PubMed  CAS  Google Scholar 

  23. Gaube, J., Feucht, H.H., Laufs, R., Polywka, S., Fingscheidt, E., Müller, H.E.: Hepatitis A, B, and C as desmoteric infections. Gesundheitswesen 1993; 55: 246–249

    PubMed  CAS  Google Scholar 

  24. Geltner, D., Naot, Y., Zimhoni, O., Gorbach, S., Bar-Khayim, Y.: Acute oliguric renal failure complicating type A nonfulminant viral hepatitis. A case presentation and review of the literature. J. Clin. Gastroenterol. 1992; 14: 160–162

    PubMed  CAS  Google Scholar 

  25. Gerritzen, A., Schneweis, K.E., Brackmann, H.-H., Oldenburg, J., Hanfland, P., Gerlich, W.H., Caspari, G.: Acute hepatitis A in haemophiliacs. Lancet 1992; 340: 1231–1232

    CrossRef  PubMed  CAS  Google Scholar 

  26. Gordon, S.C., Reddy, K.R., Schiff, L., Schiff, E.R.: Prolonged intrahepatic cholestasis secondary to acute hepatitis A. Ann. Intern. Med. 1984; 101: 635–637

    PubMed  CAS  Google Scholar 

  27. Halliday, M.L., Kang, L.-Y., Zhou, T.-K., Hu, M.-D., Pan, Q.-C., Fu, T.-Y., Huang, Y.-S., Hu, S.-L.: An epidemic of hepatitis A attributable to the ingestion of raw clams in Shanghai, China. J. Infect. Dis. 1991; 164: 852–859

    PubMed  CAS  Google Scholar 

  28. Hammond, G.W., MacDougall, B.K., Plummer, F., Sekla, L.H.: Encephalitis during prodromal stage of acute hepatitis A. Can. Med. Ass. J. 1982; 126: 269–270

    PubMed  CAS  Google Scholar 

  29. Hollinger, F.B., Khan, N.C., Oefinger, P.E., Yawn, D.H., Schmulen, A.C., Dreesman, G.R., Melnick, J.L.: Posttransfusion hepatitis A. J. Amer. Med. Ass. 1982; 250: 2313–2317

    Google Scholar 

  30. Hutin, Y.J.F., Pool, V., Cramer, E.H., Nainan, O.V., Weth, J., Williams, I.T., Goldstein, S.T., Gensheimer, K.F., Bell, B.P., Shapiro, C.N., Alter, M.J., Margolis, H.S.: A multistate foodborne outbreak of hepatitis A. New Engl. J. Med. 1999; 340: 595–602

    CrossRef  PubMed  CAS  Google Scholar 

  31. Ilan, Y., Hillman, M., Oren, R., Zlotogorski, A., Shouval, D.: Vasculitis and cryoglobulinemia associated with persisting cholestatic hepatitis A virus infection. Amer. J. Gastroenterol. 1990; 85: 586–587

    CAS  Google Scholar 

  32. Inman, R.D., Hodge, M., Johnston, M.E.A., Wright, J., Heathcote, J.: Arthritis, vasculitis, and cryoglobulinemia associated with relapsing hepatitis A virus infection. Ann. Intern. Med. 1986; 105: 700–703

    PubMed  CAS  Google Scholar 

  33. Inoue, K., Yoshiba, M., Yotsuyanagi, H., Otsuka, T., Sekiyama, K., Fujita, R.: Chronic hepatitis A with persistent viral replication. J. Med. Virol. 1996; 50: 322–324

    CrossRef  PubMed  CAS  Google Scholar 

  34. Jensenius, M., Ringertz, S.H., Berlid, D., Bell, H., Espinoza, R., Grinde, B.: Prolonged nosocomial outbreak of hepatitis A arising from an alcoholic with pneumonia. Scand. J. Infect. Dis. 1998; 30: 119–123

    PubMed  CAS  Google Scholar 

  35. Kalkan, A., Bulut, V., Avci, S., Celik, I., Bingol, N.K.: Trace elements in viral hepatitis. J. Trace Elem. Med. Biol. 2002; 16: 227–230

    CrossRef  PubMed  CAS  Google Scholar 

  36. Keeffe, E.B., Iwarson, S., McMahon, B.J., Lindsay, K.L., Koff, R.S., Manns, M., Baumgarten, R., Wiese, M., Fourneau, M., Safary, A., Clemens, R., Krause, D.S.: Safety and immunogenicity of hepaitits A vaccine in patients with chronic liver disease. Hepatology 1998; 27: 881–886

    CrossRef  PubMed  CAS  Google Scholar 

  37. Kern, G., Frisch-Niggemeyer, W., Wewalka, G., Bruns, C.: An outbreak of hepatitis A in a homeless shelter in Vienna. Wien. Klin. Wschr. 1991; 23: 364–366

    Google Scholar 

  38. Khanna, B., Spelbring, J.E., Innis, B.L., Robertson, B.H.: Characterization of a genetic variant of human hepatitis A virus. J. Med. Virol. 1992; 36: 118–124

    PubMed  CAS  Google Scholar 

  39. Klar, A., Branski, D., Nadjari, M., Akerman, M.Y., Shoseyov, D., Hurvitz, H.: Gallbladder and pancreatic involvement in hepatitis A. J. Clin. Gastroenterol. 1998; 27: 143–145

    CrossRef  PubMed  CAS  Google Scholar 

  40. Korb, G.: Virus A hepatitis. Dtsch. Med. Wschr. 1984; 109: 110–112

    PubMed  CAS  Google Scholar 

  41. Kuntz, E.: Oedematous hepatitis: a special form of acute viral hepatitis due to secondary aldosteronism. Med. Klin. 1975; 70: 274–278

    PubMed  CAS  Google Scholar 

  42. Lemon, S.M.: Type A viral hepatitis: epidemiology, diagnosis and prevention. Clin. Chemist. 1997; 43: 1494–1499

    CAS  Google Scholar 

  43. Levy, B.S., Fontaine, R.E., Smith, C.A., Brinda, J., Hirman, G., Nelson, D.B., Johnson, P.M., Larson, O.: A large food-borne outbreak of hepatitis. A. J. Amer. Med. Ass. 1975; 234: 289–294

    CAS  Google Scholar 

  44. Levy, M.J., Herrera, J.L., di Palma, J.A.: Immune globulin and vaccine therapy to prevent hepatitis A infection. Amer. J. Med. 1998; 105: 416–423

    PubMed  CAS  Google Scholar 

  45. Lyons, D.J., Gilvarry, J.M., Fielding, J.F.: Severe haemolysis associated with hepatitis A and normal glucose-6-phosphate dehydrogenase status. Gut 1990; 31: 838–839

    PubMed  CAS  Google Scholar 

  46. Mahoney, F.J., Farley, T.A., Kelso, K.Y., Wilson, S.A., Horan, J.M., McFarland, L.M.: An outbreak of hepatitis A associated with swimming in a public pool. J. Infect. Dis. 1992; 165: 613–618

    PubMed  CAS  Google Scholar 

  47. Masada, C.T., Shaw, B.W.jr., Zetterman, R.K., Kaufman, S.S., Markin, R.S.: Fulminant hepatic failure with massive necrosis as a result of hepatitis A infection. J. Clin. Gastroenterol. 1993; 17: 158–162

    PubMed  CAS  Google Scholar 

  48. Mbithi, J.N., Springthorpe, S., Boulet, J.R., Sattar, S.A.: Survival of hepatitis A virus on human hands and its transfer on contact with animate and inanimate surfaces. J. Clin. Microbiol. 1992; 30: 757–763

    PubMed  CAS  Google Scholar 

  49. Meyerhoff, A.S., Jacobs, R.J.: Transmission of hepatitis A through household contact. J. Viral Hepat. 2001; 8: 454–458

    CrossRef  PubMed  CAS  Google Scholar 

  50. Meyers, J.D., Romm, F.J., Tihen, W.S., Bryan, J.A.: Food-borne hepatitis A in a general hospital. Epidemiologic study of an outbreak attributed to sandwiches. J. Amer. Med. Ass. 1975; 231: 1049–1053

    CAS  Google Scholar 

  51. Mishu, B., Hadler, S.C., Boaz, V.A., Hutcheson, R.H., Horan, J.M., Schaffner, W.: Foodborne hepatitis A: evidence that microwaving reduces risk? J. Infect. Dis. 1990; 162: 655–658

    PubMed  CAS  Google Scholar 

  52. Mourani, S., Dobbs, St.M., Genta, R.M., Tandon, A.K., Yoffe, B.: Hepatitis A virus-associated cholecystitis. Ann. Intern. Med. 1994; 120: 398–400

    PubMed  CAS  Google Scholar 

  53. Mukhopadhya, A., Chandy, G.M.: Generalized lymphadenopathy as a marker of ongoing inflammation in prolonged cholestatic hepatitis. Eur. J. Gastroenterol. Hepatol. 2002; 14: 877–878

    CrossRef  PubMed  Google Scholar 

  54. Niu, M.T., Polish, L.B., Robertson, B.H., Khanna, B.K., Woodruff, B.A., Shapiro, C.N., Miller, M.A., Smith, J.D., Gedrose, J.K., Alter, M.J., Margolis, H.S.: Multistate outbreak of hepatitis A associated with frozen strawberries. J. Inf. Dis. 1992; 166: 518–524

    CAS  Google Scholar 

  55. O’Donovan, D., Cooke, R.P.D., Joce, R., Eastbury, A., Waite, J., Stene-Johansen, K.: An outbreak of hepatitis A amongst injecting drug users. Epidem. Infect. 2001; 127: 469–473

    CAS  Google Scholar 

  56. Ozaras, R., Mert, A., Yilmaz, M.H., Celik, A.D., Tabak, F., Bilir, M., Ozturk, R.: Acute viral cholecystitis due to hepatitis A virus infection. (case report) J. Clin. Gastroenterol. 2003; 37: 79–81

    PubMed  Google Scholar 

  57. Phillips, A.O., Thomas, D.M., Coles, G.A.: Acute renal failure associated with non-fulminant hepatitis A. Clin. Nephrol. 1993; 39: 156–157

    PubMed  CAS  Google Scholar 

  58. Pohl, Ö., Brojnas, J., Rusvai, E., Ördög, K., Siska, I., Faludi, G., Kapusinszky, B., Csohan, A., Lendvai, K., Lengyel, A., Mezey, I., Berencsi, G.: Retrospective detection of a subclinical hepatitis A virus (HAV) epidemic affecting juvenile cohorts of the Hungarian population. FEMS Immun. Med. Microbiol. 2003; 1565: 1–7

    Google Scholar 

  59. Portnoy, B.L., Mackowiak, P.A., Caraway, C.T., Walker, J.A., McKinley, T.W., Klein, C.A.jr.: Oyster-associated hepatitis. Failure of shellfish certification programs to prevent outbreaks. J. Amer. Med. Ass. 1975; 233: 1065–1068

    CAS  Google Scholar 

  60. Rahaman, S.M., Chira, P., Koff, R.S.: Idiopathic autoimmune chronic hepatitis triggered by hepatitis A. Amer. J. Gastroenterol. 1994; 89: 106–108

    CAS  Google Scholar 

  61. Rosenblum, L.S., Villarino, M.E., Nainan, O.V., Melish, M.E., Hadler, S.C., Pinsky, P.P., Jarvis, W.R., Ott, C.E., Margolis, H.S.: Hepatitis A outbreak in a neonatal intensive care unit: risk factors for transmission and evidence of prolonged viral excretion among preterm infants. J. Infect. Dis. 1991; 164: 476–482

    PubMed  CAS  Google Scholar 

  62. Rosenthal, P.: Cost-effectiveness of hepatitis A vaccination in children, adolescents, and adults. Hepatology 2003; 37: 44–51

    CrossRef  PubMed  Google Scholar 

  63. Ruel, M., Sevestre, H., Henry-Biabaud, E., Courouce, A.M., Capron, J.P., Erlinger, S.: Fibrin ring granulomas in hepatitis A. Dig. Dis. Sci. 1992; 37: 1915–1917

    CrossRef  PubMed  CAS  Google Scholar 

  64. Schiller, W.-G., Ochs, A.: Hepatitis A infection of a primate keeper as an occupational risk. Arbeitsmed. Sozialmed. Umweltmed. 1993; 28: 530–532

    Google Scholar 

  65. Schiraldi, O., Modugno, A., Miglietta, A., Fera, G.: Prolonged viral hepatitis type A with cholestasis: case report. Ital. J. Gastroenterol. 1991; 23: 364–366

    PubMed  CAS  Google Scholar 

  66. Scully, L.J., Ryan, A.E.: Urticaria and acute hepatitis A infection. Amer. J. Gastroenterol. 1993; 88: 277–278

    CAS  Google Scholar 

  67. Sheretz, R.J., Russell, B.A., Reuman, P.D.: Transmission of hepatitis A by transfusion of blood products. Arch. Intern. Med. 1984; 144: 1579–1580

    Google Scholar 

  68. Shrier, L.A., Karpen, S.J., McEvoy, C.: Acute pancreatitis associated with acute hepatitis A in a young child. J. Pediatr. 1995; 126: 57–59

    PubMed  CAS  Google Scholar 

  69. Siegl, G., Weitz, M., Kronauer, G.: Stability of hepatitis A virus. Intervirology 1984; 22: 218–226

    PubMed  CAS  Google Scholar 

  70. Simmons, W.W., Warren, R.E.: Eosinophilic pleural effusion associated with recovery from viral hepatitis A. J. Clin. Gastroenterol. 1994; 19: 143–145

    PubMed  CAS  Google Scholar 

  71. Sjogren, M.H., Tanno, H., Fay, O., Sileoni, S., Cohen, B.D., Burke, D.S., Feighny, R.J.: Hepatitis A virus in stool during clinical relapse. Ann. Intern. Med. 1987; 106: 221–226

    PubMed  CAS  Google Scholar 

  72. Staes, C.J., Schlenker, T.L., Risk, I., Cannon, K.G., Harris, H., Pavia, A.T., Shapiro, C.N., Bell, B.P.: Sources of infection among persons with acute hepatitis A and no identified risk factors during a sustained community-wide outbreak. Pediatrics 2000; 106: 63–69

    CrossRef  Google Scholar 

  73. Steffen, R., Kane, M.A., Shapiro, C.N., Billo, N., Schoellhorn, K.J., van Damme, P.: Epidemiology and prevention of hepatitis A in travelers. J. Amer. Med. Ass. 1994; 272: 885–889

    CAS  Google Scholar 

  74. Stene-Johansen, K., Jenum, P.A., Hoel, T., Blystad, H., Sunde, H., Skaug, K.: An outbreak of hepatitis A among homosexuals linked to a family outbreak. Epidem. Infect. 2002; 129: 113–117

    CAS  Google Scholar 

  75. Taliani, G., Gaeta, G.B.: Hepatitis A: post-exposure prophylaxis. Vaccine 2003; 21: 2234–2237

    PubMed  Google Scholar 

  76. Tang, Y.W., Wang, J.X., Xu, Z.Y., Guo, Y.F., Qian, W.H., Xu, J.X.: A serological confirmed, case-control study, of a large outbreak of hepatitis A in China, associated with consumption of clams. Epidemiol. Infect. 1991; 107: 651–657

    PubMed  CAS  Google Scholar 

  77. Texeira, M.R., Weller, I.V.D., Murray, A., Bamber, M., Thomas, H.C., Sherlock, S., Scheuer, P.J.: The pathology of hepatitis A in man. Liver 1982; 2: 53–60

    Google Scholar 

  78. Totsuka, A., Moritsugu, Y.: Hepatitis A virus proteins. Intervirology 1999; 42: 63–68

    CrossRef  PubMed  CAS  Google Scholar 

  79. Vento, S., Garofano, T., Di Perri, G., Dolci, L., Concia, E., Bassetti, D.: Identification of hepatitis A virus as a trigger for autoimmune chronic hepatitis type 1 in susceptible individuals. Lancet 1991; 337:1183–1187

    CrossRef  PubMed  CAS  Google Scholar 

  80. Warburton, A.R.E., Wreghitt, T.G., Rampling, A., Buttery, R., Ward, K.N., Perry, K.R., Parry, J.V.: Hepatitis A outbreak involving bread. Epidem. Infect. 1991; 106: 199–202

    CAS  Google Scholar 

  81. Watson, J.C., Fleming, D.W., Borella, A.J., Olcott, E.S., Conrad, R.E., Baron, R.C.: Vertical transmission of hepatitis A resulting in an outbreak in a neonatal intensive care unit. J. Infect. Dis. 1993; 167:567–571

    PubMed  CAS  Google Scholar 

  82. Wolf, M., Oneta, C.M., Jornod, P., Seld, D., Wauters, J.P., Blum, A.L., Delarive, J.: Cholestatic hepatitis A complicated by acute renal insufficiency. Zschr. Gastroenterol. 2001; 39: 519–522

    CAS  Google Scholar 

  83. Zaaijer, H.L., Leentvaarkuipers, A., Rotman, H., Lelie, P.N.: Hepatitis A antibody titres after infection and immunization-implications for passive and active immunization. J. Med. Virol. 1993; 40: 22–27

    PubMed  CAS  Google Scholar 

  84. Zikos, D., Grewal, K.S., Craig, K., Jen-Chieh-Cheng, Peterson, D.R., Fisher, K.A.: Nephrotic syndrome and acute renal failure associated with hepatitis A virus infection. Amer. J. Gastroenterol. 1995; 90:295–298

    CAS  Google Scholar 

Acute viral hepatitis B

  1. Akahane, Y., Okada, S., Sakamoto, M., Wakamiya, M., Kitamura, T., Tawara, A., Naitoh, S., Tsuda, F., Okamoto, H.: Persistence of hepatitis B viremia after recovery from acute hepatitis B: correlation between anti-HBc titer and HBV DNA in serum. Hepatol. Res. 2002; 24: 8–17

    PubMed  CAS  Google Scholar 

  2. Alter, M.J.: Epidemiology and prevention of hepatitis B. Semin. Liver Dis. 2003; 23: 39–46

    CrossRef  PubMed  Google Scholar 

  3. Alward, W.L.M., McMahon, B.J., Hall, D.B., Heyward, W.L., Francis, D.P., Bender, T.R.: The long-term serological course of asymptomatic hepatitis B virus carriers and the development of primary hepatocellular carcinoma. J. Infect. Dis. 1985; 151: 604–609

    PubMed  CAS  Google Scholar 

  4. Ayoola, E.A., Johnson, A.O.K.: Hepatitis B vaccine in pregnancy: immunogenicity, safety and transfer of antibodies to infants. Int. J. Gynaecol. Obstet. 1987; 25: 297–301

    CrossRef  PubMed  CAS  Google Scholar 

  5. Benvegnu, L., Fattovich, G., Noventa, F., Tremolada, F., Chemello, L., Cecchetto, A., Alberti, A.: Concurrent hepatitis B and C virus infection and risk of hepatocellular carcinoma in cirrhosis. Cancer 1994; 74:2442–2448

    PubMed  CAS  Google Scholar 

  6. Bianco, E., Stroffolini, T., Spada, E., Szklo, A., Marzolini, F., Ragni, P., Gallo, G., Balocchini, E., Parlato, A., Sangalli, M., Lopalco, P.L., Zotti, C., Mele, A.: Case fatality rate of acute viral hepatitis in Italy: 1995–2000. An update. Dig. Liver Dis. 2003; 35: 404–408

    CAS  Google Scholar 

  7. Boxall, E.H., Flewett, T.H., Dane, D.S., Cameron, C.H., MacCallum, F.O., Lee, T.W.: Hepatitis-B surface antigen in breast milk. Lancet 1974/II: 1007–1008

    Google Scholar 

  8. Broderick, A.L., Jonas, M.M.: Hepatitis B in children. Semin. Liver Dis. 2003; 23: 59–68

    CrossRef  PubMed  Google Scholar 

  9. Brown, J.L., Carman, W.F., Thomas, H.C.: The hepatitis B virus. Clin. Gastroenterol. 1990; 4: 721–746

    CAS  Google Scholar 

  10. Brunetto, M.R., Rodriguez, U.A., Bonino, F.: Hepatitis B virus mutants. Intervirology 1999; 42: 69–80

    CrossRef  PubMed  CAS  Google Scholar 

  11. Calvet, X., Bruix, J., Bosch, J., Rodes, J.: Portal pressure in patients with exudative ascites in the course of acute hepatitis B. Liver 1991;11: 206–210

    PubMed  CAS  Google Scholar 

  12. Carman, W.F., Fagan, E.A., Hadziyannis, St., Karayiannis, P., Tassapoulos, N.C., Williams, R., Thomas, H.C.: Association of a precore genomic variant of hepatitis B virus with fulminant hepatitis. Hepatology 1991; 14: 219–222

    CrossRef  PubMed  CAS  Google Scholar 

  13. Castro, A., Roget, M., Buti, M., Chamoun, A., Jardi, R., Esteban, R., Guardia, J.: Derrame pleural en el curso de una hepatitis aguda B. Gastroenterol. Hepatol. 1991; 14: 247–249

    Google Scholar 

  14. Chang, M.-H., Hwang, L.-H., Hsu, H.-C., Lee, C.-Y., Beasley, R.P.: Prospective study of asymptomatic HBsAg carrier children infected in the perinatal period: clinical and liver histologic studies. Hepatology 1988; 8: 374–377

    PubMed  CAS  Google Scholar 

  15. Chen, W.N., Oon, C.J.: Hepatitis B virus mutants: An overview. J. Gastroenterol. Hepatol. 2002; 17(Suppl.): 497–499

    CAS  Google Scholar 

  16. Chobe, L.P., Chadha, M.S., Arankalle, V.A., Gogate, S.S., Banerjee, K.: Hepatitis B infection among dental personnel in Pune and Bombay (India). Indian J. Med. Res. 1991; 93(A): 143–146

    PubMed  CAS  Google Scholar 

  17. Chu, C.J., Hussain, M., Lok, A.S.F.: Hepatitis B virus genotype B is associated with earlier Hbe Ag seroconversion compared with hepatitis B virus genotype C. Gastroenterology 2002; 122: 1756–1762

    CrossRef  PubMed  CAS  Google Scholar 

  18. Clement, F., Dewint, P., Leroux-Roels, G.: Evaluation of a new rapid test for the combined detection of hepatitis B virus surface antigen and hepatitis B virus e antigen. J. Clin. Microbiol. 2002; 40: 4603–4606

    CrossRef  PubMed  CAS  Google Scholar 

  19. Combes, B., Shorey, J., Barrera, A., Stastny, P., Eigenbrodt, E.H., Hull, A.R., Carter, N.W.: Glomerulonephritis with deposition of Australia antigen-antibody complexes in glomerular basement membrane. Lancet 1991/II: 234–237

    Google Scholar 

  20. Comer, G.M., Mittal, M.K., Donelson, S.S., Lee, T.-P.: Cluster of fulminant hepatitis B in crack users. Amer. J. Gastroenterol. 1991; 86:331–334

    CAS  Google Scholar 

  21. Connor, F.L., Rosenberg, A.R., Kennedy, S.E., Bohane, T.D.: HBV associated nephrotic syndrome: resolution with oral lamivudine (case report). Arch. Dis. Childh. 2003; 88: 446–449

    PubMed  CAS  Google Scholar 

  22. Craxi, A., Tine, F., Vinci, M., Almasio, P., Camma, C., Garofalo, G., Pagliaro, L.: Transmission of hepatitis B and hepatitis delta viruses in the households of chronic hepatitis B surface antigen carriers: A regression analysis of indicators of risk. Amer. J. Epidemiol. 1991;134: 641–650

    CAS  Google Scholar 

  23. De Franchis, R., Meucci, G., Vecchi, M., Tatarella, M., Colombo, M., del Ninno, E., Rumi, M.G., Donato, M.F., Ronchi, G.: The natural history of asymptomatic hepatitis B surface antigen carriers. Ann. Intern. Med. 1993; 118: 191–194

    PubMed  Google Scholar 

  24. Dentico, P., Volpe, A., Buongiorno, R., Maracchione, N., Carbone, M., Manno, C., Proscia, F.: Immunogenicity and efficacy of anti-hepatitis B vaccines in hemodialysis patients. Nephron 1992; 61: 324–325

    PubMed  CAS  Google Scholar 

  25. Devesa, F., Martinez, F., Moreno, M.J., Sanfrancisco, M., Ferrando, J., Rull, S.: Marcadores de la hepatitis B en tres centros abiertos para disminuidos psiquicos. Rev. Esp. Enf. Digest. 1993; 84: 162–168

    CAS  Google Scholar 

  26. Diamantis, I.D., McGandy, Ch.E., Cheng, T.-J., Liaw, Y.-F., Gudat, F., Bianchi, L.: Hepatitis BX-gene expression in hepatocellular carcinoma. J. Hepatol. 1992; 15: 400–403

    CrossRef  PubMed  CAS  Google Scholar 

  27. Dienstag, J.L., Wands, J.R., Isselbacher, K.J.: Hepatitis B and essential mixed cryoglobulinemia. New Engl. J. Med. 1977; 297: 946

    PubMed  CAS  Google Scholar 

  28. Dienstag, J.L., Rhodes, A.R., Bhan, A.K., Dvorak, A.M., Mihm, M.C.jr., Wands, J.R.: Urticaria associated with acute viral hepatitis type B. Studies of pathogenesis. Ann. Intern. Med. 1978; 89: 34–40

    PubMed  CAS  Google Scholar 

  29. Fabris, P., Tositti, G., Mazzella, G., Zanetti, A.R., Nicolin, R., Pellizzer, G., Benedetti, P., de Lalla, F.: Effect of ursodeoxycholic acid administration in patients with acute viral hepatitis: a pilot study. Aliment. Pharm. Ther. 1999; 13: 1187–1193

    CAS  Google Scholar 

  30. Fattovich, G.: Natural history and prognosis of hepatitis B. Semin. Liver Dis. 2003; 23: 47–58

    CrossRef  PubMed  Google Scholar 

  31. Fisker, N., Georgsen, J., Stolborg, T., Khalil, M.R., Christensen, P.B.: Low hepatitis B prevalence among pre-school children in Denmark: saliva anti-HBc screening in day care centres. J. Med. Virol. 2002; 68:500–504

    CrossRef  PubMed  Google Scholar 

  32. Fisman, D.N., Agrawal, D., Leder, K.: The effect of age on immunologic response to recombinant hepatitis B vaccine: A meta-analysis. Clin. Infect. Dis. 2002; 35: 1368–1375

    CrossRef  PubMed  Google Scholar 

  33. Flisiak, R., Prokopowicz, D.: Effect of misoprostol on serum beta(2)-microglobulin in the course of viral hepatitis B. Eur. J. Gastroenterol. Hepatol. 1999; 11: 1227–1230

    PubMed  CAS  Google Scholar 

  34. Galsky, J., Bansky, G., Holubova, T., König, J.: Effect of ursodeoxycholic acid in acute viral hepatitis. J. Clin. Gastroenterol. 1999; 28:249–253

    CrossRef  PubMed  CAS  Google Scholar 

  35. Gerlich, W.H., Thomssen, R.: An outbreak of hepatitis B in a butchery. Dtsch. Med. Wschr. 1982; 107: 1627–1630

    PubMed  CAS  Google Scholar 

  36. Gianotti, F.: Papular acrodermatitis of childhood: an australia antigen disease. Arch. Dis. Childh. 1973; 48: 794–799

    PubMed  CAS  Google Scholar 

  37. Gilson, R.J.C.: Sexually transmitted hepatitis: a review. Genitourin. Med. 1992; 68: 123–129

    PubMed  CAS  Google Scholar 

  38. Giotakos, O., Bourtsoukli, P., Paraskeyopoulou, T., Spandoni, P., Stasinos, S., Boulougouri, D., Spirakou, E.: Prevalence and risk factors of HIV, hepatitis B and hepatitis C in a forensic population of rapists and child molesters. Epidem. Infect. 2003; 130: 497–500

    CAS  Google Scholar 

  39. Glück, T., Weber, P., Wiedmann, K.H.: Hepatitis B-associated vasculitis. Dtsch. Med. Wschr. 1994; 119: 1388–1392

    PubMed  Google Scholar 

  40. Grob, P.J., Bischoff, B., Naeff, F.: Cluster of hepatitis B transmitted by a physician. Lancet 1981/II: 1218–1220

    Google Scholar 

  41. Hadler, S.C., Francis, D.P., Maynard, J.E., Thompson, S.E., Judson, F.N., Echenberg, D.F., Ostrow, D.G., O’Malley, P.M., Penley, K.A., Altman, N.L., Braff, E., Shipman, G.F., Coleman, P.J., Mandel, E.J.: Long-term immunogenicity and efficacy of hepatitis B vaccine in homosexual men. New Engl. J. Med. 1986; 315: 211–214

    Google Scholar 

  42. Hadler, S.C., Sorley, D.L., Acree, K.H., Webster, H.M., Schable, Ch.A., Francis, D.P., Maynard, J.E.: An outbreak of hepatitis B in a dental practice. Ann. Intern. Med. 1981; 95: 133–138

    PubMed  CAS  Google Scholar 

  43. Hadziyannis, S., Gerber, M.A., Vissoulis, C., Popper, H.: Cytoplasmic hepatitis B antigen in “ground-glass” hepatocytes of carriers. Arch. Pathol. 1973; 96: 327–330

    PubMed  CAS  Google Scholar 

  44. Halfon, P., Pol, S., Bourliere, M., Cacoub, P.: Hepatitis B virus genotypes: clinical, epidemiological and therapeutic implications. Gastroenterol. Clin. Biol. 2002; 26: 1005–1012

    PubMed  Google Scholar 

  45. Harpaz, R., von Seidlein, L., Averhoff, F.M., Tormey, M.P., Sinha, S.D., Kotsopoulou, K., Lambert, S.B., Robertson, B.H., Cherry, J.D., Shapiro, C.N.: Transmission of hepatitis B virus to multiple patients from a surgeon without evidence of inadequate infection control. New Engl. J. Med. 1996; 334: 549–554

    CrossRef  PubMed  CAS  Google Scholar 

  46. Homann, J., Petri, F., Deetjen, W., Kuntz, E., Matthes, K.J., Zellmer, R., Eimiller, A., Paul, F.: Therapeutic effect of ursodeoxycholic acid in acute viral hepatitis? Z. Gastroenterol. 1988; 26: 623.

    Google Scholar 

  47. Hoofnagle, J.H., Shafritz, D.A., Popper, H.: Chronic type B hepatitis and the “healthy” HBsAg carrier state. Hepatology 1987; 7: 758–763

    PubMed  CAS  Google Scholar 

  48. Hopkins, R., Kanne, E., Robertson, A.E., Haase, G.: Hepatitis B virus transmitted by HBsAg-negative blood containing anti-HBc. Med. Lab. Sci. 1982; 39: 61–62

    PubMed  CAS  Google Scholar 

  49. Hurlen, B., Jonsen, J., Aas, E.: Viral hepatitis in dentists in Norway. Acta Odont. Scand. 1980; 38: 321–324

    PubMed  CAS  Google Scholar 

  50. Hutin, Y.J.F., Goldstein, S.T., Varma, J.K., Odair, J.B., Mast, E.E., Shapiro, C.N., Alter, M.J.: An outbreak of hospital-acquired hepatitis B virus infection among patients receiving chronic hemodialysis. Inf. Contr. Hosp. Epid. 1999; 20: 731–735

    CAS  Google Scholar 

  51. Ide, T., Sata, M., Nouno, R., Yamashita, F., Nakano, H., Tanikawa, K.: Clinical evaluation of four cases of acute viral hepatitis complicated by pure red cell aplasia. Amer. J. Gastroenterol. 1994; 89: 257–262

    CAS  Google Scholar 

  52. Inman, R.D.: Rheumatic manifestations of hepatitis B virus infection. Semin. Arthr. Rheum. 1982; 11: 406–420

    CAS  Google Scholar 

  53. Joffe, B., Noonan, C.A.: Hepatitis B virus. New and evolving issues. Dig. Dis. Sci. 1992; 37: 1–9

    Google Scholar 

  54. Joh, R., Hasegawa, K., Ogawa, M., Ishikawa, K., Iizuka, A., Naritomi, T., Kanai, N., Torii, N., Hashimoto, E., Hayashi, N.: Genotypic analysis of hepatitis B virus from patients with fulminant hepatitis: comparison with acute self-limited hepatitis. Hepatol. Res. 2003; 26: 119–124

    PubMed  CAS  Google Scholar 

  55. Jung, S., Lee, H.C., Han, J.M., Lee, Y.L., Chung, Y.H., Lee, Y.S., Kwon, Y., Yu, E.S., Suh, D.J.: Four cases of hepatitis B virus-related fibrosing cholestatic hepatitis treated with lamivudine (case report). J. Gastroenterol. Hepatol. 2002; 17: 345–350

    CrossRef  PubMed  Google Scholar 

  56. Kaganov, B.S., Nisevich, N.I., Uchaikin, V.F., Konev, V.A., Levina, E.I., Sizich, N.N., Chapligina, G.V.: Acute viral hepatitis B in children: lack of chronicity. Lancet 1990; 336: 374–375

    CrossRef  PubMed  CAS  Google Scholar 

  57. Kalayci, C., Johnson, P.J., Davies, S.E., Williams, R.: Hepatitis B virus related hepatocellular carcinoma in the non-cirrhotic liver. J. Hepatol. 1991; 12: 54–59

    CrossRef  PubMed  CAS  Google Scholar 

  58. Karayiannis, P., Novick, D.M., Lok, A.S.F., Fowler, M.J.F., Monjardino, J., Thomas, H.C.: Hepatitis B virus DNA in saliva, urine, and seminal fluid of carriers of hepatitis Be antigen. Brit. Med. J. 1985;290: 1853–1855

    CAS  Google Scholar 

  59. Khan, A.J., Cotter, S.M., Schulz, B., Hu, Y.L., Rosenberg, J., Robertson, B.H., Fiore, A.E., Bell, B.R.: Nosocomial transmission of hepatitis B virus infection among residents with diabetes in a skilled nursing facility. Inf. Contr. Hosp. Epidem. 2002; 23: 313–318

    Google Scholar 

  60. Kobler, E., Schmuziger, P., Hartmann, G.: Hepatitis resulting from acupuncture. Schweiz. Med. Wschr. 1979; 109: 1828–1829

    PubMed  CAS  Google Scholar 

  61. Korman, S.H.: Thrombocytopenic purpura during the incubation of hepatitis B. Acta Paediatr. Scand. 1991; 80: 975–976

    PubMed  CAS  Google Scholar 

  62. Kosaka, Y., Takase, K., Kojima, M., Shimizu, M., Inoue, K., Yoshiba, M., Tanaka, S., Akahane, Y., Okamoto, H., Tsuda, F., Miyakawa, Y., Mayumi, M.: Fulminant hepatitis-B-induction by hepatitis-B virus mutants defective in the precore region and incapable of encoding eantigen. Gastroenterology 1991; 100: 1087–1094

    PubMed  CAS  Google Scholar 

  63. Krebs, H.-J.: Hepatitis B in dentists and dental staff. Münch. Med. Wschr. 1985; 127: 462–463

    Google Scholar 

  64. Kunches, L.M., Craven, D.E., Werner, B.G., Jacobs, L.M.: Hepatitis B exposure in emergency medical personnel. Prevalence of serologic markers and need for immunization. Amer. J. Med. 1983; 75: 269–272

    PubMed  CAS  Google Scholar 

  65. Kuntz, E., Kuntz, A.: Prohibition to practice for dentists in the case of unfavourable hepatitis B serology. Münch. Med. Wschr. 1978; 120:1407–1410; 1979; 121: 114–115

    CAS  Google Scholar 

  66. Kuntz, E.: Viral hepatitis and dental practice. Der Freie Zahnarzt 1982; 988–993

    Google Scholar 

  67. Lai, F.M.-M., Lai, K.N., Tam, J.S.L., Lui, S.F., To, K.F., Li, P.K.T.: Primary glomerulonephritis with detectable glomerular hepatitis B virus antigens. Amer. J. Surg. Path. 1994; 18: 175–186

    CAS  Google Scholar 

  68. Lau, D.T.Y., Ma, H., Lemon, S.M., Doo, E., Ghany, M.G., Miskovsky, E., Woods, G.L., Park, Y., Hoofnagle, J.H.: A rapid immunochromatographic assay for hepatitis B virus screening. J. Viral Hepat. 2003; 10:331–334

    CrossRef  PubMed  Google Scholar 

  69. Lau, J.Y.N., Wright, T.L.: Molecular virology and pathogenesis of hepatitis B. Lancet 1993; 342: 1335–1340

    PubMed  CAS  Google Scholar 

  70. LeBrecque, D.R., Muhs, J.M., Lutwick, L.I., Woolson, R.F., Hierholzer, W.R.: The risk of hepatitis B transmission from health care workers to patients in a hospital setting — a prospective study. Hepatology 1986;6: 205–208

    Google Scholar 

  71. Lee, W.H.: Hepatitis B virus infection. New Engl. J. Med. 1997; 337:1733–1745

    CrossRef  PubMed  CAS  Google Scholar 

  72. Liang, T.J., Hasegawa, K., Rimon, N., Wands, J.R., Ben-Porath, E.: A hepatitis B virus mutant associated with an epidemic of fulminant hepatitis. New Engl. J. Med. 1991; 324: 1705–1709

    PubMed  CAS  Google Scholar 

  73. Limentani, A.E., Elliot, L.M., Noah, N.D., Lamborn, J.K.: An outbreak of hepatitis B from tattooing. Lancet 1979/II: 86–88

    Google Scholar 

  74. Lin, H.-H., Hsu, H.-Y., Chang, M.-H., Chen, P.-J., Chen, P.-S.: Hepatitis B virus in the colostra of HBeAg-positive carrier mothers. J. Pediatr. Gastroenterol. Nutr. 1993; 17: 207–210

    PubMed  CAS  Google Scholar 

  75. Ljunggren, K., Hanson, B.G., Nordenfelt, E.: HBsAg/IgM complexes as a prognostic marker of chronicity in acute hepatitis B virus infection. Scand. J. Infect. Dis. 1991; 23: 529–534

    PubMed  CAS  Google Scholar 

  76. Locarnini, S.: Molecular virology of hepatitis B virus. Semin. Liver Dis. 2004; 24(Suppl.): 3–10

    PubMed  CAS  Google Scholar 

  77. Lok, A.S.F., Lai, C.L., Hui, W.M., Matthew, M.T., Wu, P.C., Lam, S.K., Leung, E.K.Y.: Absence of transmission of hepatitis B by fibreoptic upper gastrointestinal endoscopy. J. Gastroenterol. Hepatol. 1987;2: 175–180

    Google Scholar 

  78. Lok, A.S.F., Liang, R.H.S., Chiu, E.K.W., Wong, K.-L., Chan, T.-K., Todd, D.: Reactivation of hepatitis B virus replication in patients receiving cytotoxic therapy. Gastroenterology 1991; 100: 182–188

    PubMed  CAS  Google Scholar 

  79. Lok, A.S.F.: Hepatitis B: Progress in the last decade. Semin. Liver Dis. 2003; 23: 1–4

    CrossRef  PubMed  Google Scholar 

  80. Lortholary, O., Molinie, V., Jaccard, A., Amarenco, G., Boudes, P., Amouroux, J., Guillevin, L.: Bladder neuropathy and gastric paralysis in polyarteritis nodosa associated with hepatitis B virus. Scand. J. Rheumat. 1990; 19: 442–443

    CAS  Google Scholar 

  81. Luo, K.X., Zhou, R., He, C., Liang, Z.S., Jiang, S.: Hepatitis B virus DNA in sera of virus carriers positive exclusively for antibodies to the hepatitis B core antigen. J. Med. Virol. 1991; 35: 55–59

    PubMed  CAS  Google Scholar 

  82. Marcellin, P., Martinot-Peignoux, M., Loriot, M.-A., Giostra, E., Boyer, N., Thiers, V., Benhamou, J.-P.: Persistence of hepatitis B virus DNA demonstrated by polymerase chain reaction in serum and liver after loss of HBsAg induced by antiviral therapy. Ann. Intern. Med. 1990; 112: 227–228

    PubMed  CAS  Google Scholar 

  83. Marie-Cardine, A., Mouterde, O., Dubuisson, S., Buffet-Janvresse, C., Mallet, E.: Salivary transmission in an intrafamilial cluster of hepatitis B. J. Pediatr. Gastroenterol. Nutrit. 2002; 34: 227–230

    Google Scholar 

  84. Marinho, R.T., Moura, M.C., Pedro, M., Ramalho, F.J., Velosa, J.F.: Hepatitis B vaccination in hospital personnel and medical students. J. Clin. Gastroenterol. 1999; 28: 317–322

    CrossRef  PubMed  CAS  Google Scholar 

  85. Marion, P.L., Oshiro, L.S., Regnery, D.C., Scullard, G.H., Robinson, W.S.: A virus in beechey ground squirrels which is related to hepatitis B virus in man. Proc. Natl. Acad. Sci. USA 1980; 77: 2941–2945

    PubMed  CAS  Google Scholar 

  86. Mason, W.S., Seal, G., Summers, J.: Virus of Peking ducks with structure and biological relatedness to human hepatitis B virus. J. Virol. 1980; 36: 829–836

    PubMed  CAS  Google Scholar 

  87. Mayans, M.V., Hall, A.J., Inskip, H.M., Lindsay, S.W., Chotard, J., Mendy, M., Whittle, H.C.: Do bedbugs transmit hepatitis B? Lancet 1994; 343: 761–763

    PubMed  CAS  Google Scholar 

  88. McSweeney, P.A., Carter, J.M., Green, G.J., Romeril, K.R.: Fatal aplastic anemia associated with hepatitis B viral infection. Amer. J. Med. 1988; 85: 255–256

    PubMed  CAS  Google Scholar 

  89. Michalak, T.: Immune complexes of hepatitis B surface antigen in the pathogenesis of periarteritis nodosa. A study of seven necropsy cases. Amer. J. Pathol. 1978; 90: 619–628

    CAS  Google Scholar 

  90. Milbradt, R., Nasemann, T.: The entity of the Gianotti-Crosti syndrome and its relationship to hepatitis B infection. Hautarzt 1975;26: 471–479

    PubMed  CAS  Google Scholar 

  91. Moyer, L.A., Alter, M.J., Favero, M.S.: Hemodialysis-associated hepatitis B: revised recommendations for serologic screening. Semin. Dialysis 1990; 3: 201–205

    Google Scholar 

  92. Murakami, S.: Hepatitis B virus X protein: structure, function and biology. Intervirology 1999; 42: 81–99

    CrossRef  PubMed  CAS  Google Scholar 

  93. Nakamura, H., Shimizu, T., Ohshiro, S., Aoki, H., Kaneko, M., Shioda, A., Saitoh, T., Moriyama, M., Tanaka, N., Arakawa, Y.: An adult patient with acute hepatitis type B which was protracted and complicated by polyarteritis nodosa: A case report. Hepatol. Res. 2002; 24:439–444

    PubMed  Google Scholar 

  94. Nassal, M.: Hepatitis B virus replication: novel roles for virus-host interactions. Intervirology 1999; 42: 100–116

    CrossRef  PubMed  CAS  Google Scholar 

  95. Newkirk, M.M., Downe, A.E.R., Simon, J.B.: Fate of ingested hepatitis B antigen in blood-sucking insects. Gastroenterology 1975; 69:982–987

    PubMed  CAS  Google Scholar 

  96. Odeh, M., Oliven, A.: Treatment of prolonged cholestasis of acute hepatitis B with ursodeoxycholic acid. Hepat. Res. 1998; 13: 37–41

    Google Scholar 

  97. O’Gorman, M.A., Sharma, S., Groopman, J.D., Tennant, B.C., Tochkov, I.A., Schwarz, K.B.: Decreased oxidative DNA damage and accelerated cell turnover in woodchuck hepatitis virus infected liver. Hepatol. Res. 2003; 25: 254–262

    PubMed  CAS  Google Scholar 

  98. Ogston, C.W., Wittenstein, F.S., London, W.T., Millman, I.: Persistence of hepatitis B surface antigen in the bedbug Cimex hemipterus (Fabr.). J. Infect. Dis. 1979; 140: 411–414

    PubMed  CAS  Google Scholar 

  99. Oleske, J., Minnefor, A., Cooper, R.jr., Ross, J., Gocke, D.: Transmission of hepatitis B in a classroom setting. J. Pediatr. 1980; 97: 770–772

    PubMed  CAS  Google Scholar 

  100. Omata, M., Uchiumi, K., Ito, Y., Yokosuka, O., Mori, J., Terao, K., Ye, W.-F., O’Connell, A.P., London, W.T., Okuda, K.: Duck hepatitis B virus and liver diseases. Gastroenterology 1983; 85: 260–267

    PubMed  CAS  Google Scholar 

  101. Omata, M.: Significance of extrahepatic replication of hepatitis B virus. Hepatology 1990; 12: 364–366

    PubMed  CAS  Google Scholar 

  102. Oren, I., Hershow, R.C., Ben-Porath, E., Krivoy, N., Goldstein, N., Rishpon, S., Shouval, D., Hadler, S.C., Alter, M.J., Maynard, J.E., Alroy, G.: A common-source outbreak of fulminant hepatitis B in a hospital. Ann. Intern. Med. 1989; 110: 691–698

    PubMed  CAS  Google Scholar 

  103. Penner, E., Maida, E., Mamoli, B., Gangl, A.: Serum and cerebrospinal fluid immune complexes containing hepatitis B surface antigen in Guillain-Barre syndrome. Gastroenterology 1982; 82: 576–580

    PubMed  CAS  Google Scholar 

  104. Perlman, D., Hu, H.M.: Duck hepatitis B virus virion secretion requires a double-stranded DNA genome. J. Virol. 2003; 77: 2287–2294

    CrossRef  PubMed  CAS  Google Scholar 

  105. Piazza, M., Guadagnino, V., Picciotto, L., Borgia, G., Nappa, S.: Contamination by hepatitis B surface antigen in dental surgeries. Brit. Med. J. 1987; 295: 473–474

    CAS  Google Scholar 

  106. Polakoff, S.: Acute hepatitis B in patients in Britain related to previous operations and dental treatment. Brit. Med. J. 1986; 293: 33–36

    CAS  Google Scholar 

  107. Polish, L.B., Shapiro, C.N., Bauer, F., Klotz, P., Ginier, P., Roberto, R., Margolis, H.S., Alter, M.J.: Nosocomial transmission of hepatitis B virus associated with the use of a spring-loaded finger-stick device. New Engl. J. Med. 1992; 326: 721–725

    PubMed  CAS  Google Scholar 

  108. Pontisso, P., Morsica, G., Ruvoletto, M.G., Barzon, M., Perilongo, G., Basso, G,. Cecchetto, G., Chemello, L., Alberti, A.: Latent hepatitis B virus infection in childhood hepatocellular carcinoma. Analysis by polymerase chain reaction. Cancer 1992; 69: 2731–2735

    PubMed  CAS  Google Scholar 

  109. Porres, J.C., Carreno, V., Bartolome, J., Gutiez, J., Castillo, I.: A dynamic study of the intrafamilial spread of hepatitis B virus infection. Relation with the viral replication. J. Med. Virol. 1989; 28: 237–242

    PubMed  CAS  Google Scholar 

  110. Prassolov, A., Hohenberg, H., Kalinina, T., Schneider, C., Cova, L., Krone, O., Frolich, K., Will, H., Sirma, H.: New hepatitis B virus of cranes that has an unexpected broad host range. J. Virol. 2003; 77: 1964–1976

    CrossRef  PubMed  CAS  Google Scholar 

  111. Prati, D.: Transmission of viral hepatitis by blood and blood derivatives: current risks, past heritage. Dig. Dis. Sci. 2002; 34: 812–817

    CAS  Google Scholar 

  112. Pumpens, P., Grens, E., Nassal, M.: Molecular epidemiology and immunology of hepatitis B virus infection. An update. Intervirology 2002; 45: 218–232

    PubMed  CAS  Google Scholar 

  113. Quale, J.M., Landman, D., Wallace, B., Atwood, E., Ditore, V., Fruchter, G.: Déjà vu: Nosocomial hepatitis B virus transmission and fingerstick monitoring. Amer. J. Med. 1998; 105: 296–301

    PubMed  CAS  Google Scholar 

  114. Radvan, G.H., Hewson, E.G., Berenger, S., Brookman, D.J.: The Newcastle hepatitis B outbreak. Observations on cause, management and prevention. Med. J. Aust. 1986; 144: 461–464

    PubMed  CAS  Google Scholar 

  115. Rehermann, B.: Immune responses in hepatitis B virus infection. Semin. Liver Dis. 2003; 23: 21–37

    CrossRef  PubMed  CAS  Google Scholar 

  116. Rich, J.D., Ching, C.G., Lally, M.A., Gaitanis, M.M., Schwartzapfel, B., Charuvastra, A., Beckwith, C.G., Flanigan, T.P.: A review of the case for hepatitis B vaccination of high-risk adults. Amer. J. Med. 2003; 114: 316–318

    PubMed  Google Scholar 

  117. Rosenblum, L., Darrow, W., Witte, J., Cohen, J., French, J., Gill, P.S., Potterat, J., Sikes, K., Reich, R., Hadler, S.: Sexual practices in the transmission of hepatitis B virus and prevalence of hepatitis delta virus infection in female prostitutes in the United States. J. Amer. Med. Ass. 1992; 267: 2477–2481

    CAS  Google Scholar 

  118. Rosman, A.S., Basu, P., Galvin, K., Lieber, C.S.: Efficacy of a high and accelerated dose of hepatitis B vaccine in alcoholic patients: a randomized clinical trial. Amer. J. Med. 1997; 103: 217–222

    PubMed  CAS  Google Scholar 

  119. Rossner, M.T.: Review: Hepatitis B virus X-gene product: A promiscuous transcriptional activator. J. Med. Virol. 1992; 36: 101–117

    PubMed  CAS  Google Scholar 

  120. Ruiz, J., Sangro, B., Cuende, J.I., Beloqui, O., Riezu-Boj, J.I., Herrero, J.I., Prieto, J.: Hepatitis B and C viral infections in patients with hepatocellular carcinoma. Hepatology 1992; 16: 637–641

    PubMed  CAS  Google Scholar 

  121. Saracco, G., Macagno, S., Rosina, F., Caredda, F., Antinori, S., Rizzetto, M.: Serologic markers with fulminant hepatitis in persons positive for hepatitis B surface antigen. A worldwide epidemiologic and clinical survey. Ann. Intern. Med. 1988; 108: 380–383

    PubMed  CAS  Google Scholar 

  122. Schiodt, F.V., Davern, T.J., Shakil, A.O., McGuire, G., Lee, W.M.: Viral hepatitis-related acute liver failure. Amer. J. Gastroenterol. 2003; 98: 448–453

    Google Scholar 

  123. Sebastian, V.J., Ray, S., Bhattacharya, S., Tin Maung, O., Md Saini, H.A., HJ Daud Jalani: Tattooing and hepatitis B infection. J. Gastroenterol. Hepatol. 1992; 7: 385–387

    PubMed  CAS  Google Scholar 

  124. Shafritz, D.A.: Variants of hepatitis B virus associated with fulminant liver disease. New Engl. J. Med. 1991; 324: 1737–1738

    PubMed  CAS  Google Scholar 

  125. Solis Herruzo, J.A., Munoz-Yague, T.: Polyarteritis nodosa and hepatitis B virus infection. Rev. Esp. Enferm. Dig. 2003; 95: 156.

    PubMed  CAS  Google Scholar 

  126. Spijkerman, I.J.B., van Doorn, L.J., Janssen, M.H.W., Wijkmans, C.J., Bikert-Mooiman, M.A.J., Coutinho, R.A., Weers-Pothoff, G.: Transmission of hepatitis B virus from a surgeon to his patients during high-risk and low-risk surgical procedures during 4 years. Inf. Contr. Hosp. Epidem. 2002; 23: 306–312

    Google Scholar 

  127. Tabor, E.: Guillain-Barre syndrome and other neurologic syndromes in hepatitis A, B, non-A, non-B. J. Med. Virol. 1987; 21: 207–216

    PubMed  CAS  Google Scholar 

  128. Torii, N., Hasegawa, K., Ogawa, M., Hashimo, E., Hayashi, N.: Effectiveness and long-term outcome of lamivudine therapy for acute hepatitis B. Hepatol. Res. 2002; 24: 34–41

    PubMed  CAS  Google Scholar 

  129. Ursell, P.C., Habib, A., Sharma, P., Mesa-Tejada, R., Lefkowitch, J.H., Fenoglio, J.J.jr.: Hepatitis B virus and myocarditis. Hum. Pathol. 1984; 15: 481–484

    PubMed  CAS  Google Scholar 

  130. Van Zonneveld, M., van Nunen, A.B., Niesters, H.G.M., de Man, R.A., Schalm, S.W., Janssen, H.L.A.: Lamivudine treatment during pregnancy to prevent perinatal transmission of hepatitis B virus infection. J. Viral Hepat. 2003; 10: 294–297

    CrossRef  PubMed  Google Scholar 

  131. Vanclaire, J., Cornu, Ch., Sokal, E.M.: Fulminant hepatitis B as an infant born to a hepatitis Be antibody positive, DNA negative carrier. Arch. Dis. Childh. 1991; 66: 983–985

    PubMed  CAS  Google Scholar 

  132. Venkataseshan, V.S., Lieberman, K., Kim, D.U., Thung, S.N., Dikman, S., D’Agati, V., Susin, M., Valderrama, E., Gauthier, B., Prakash, A., Churg, J.: Hepatitis-B-associated glomerulonephritis: pathology, pathogenesis, and clinical course. Medicine (Baltimore) 1990; 69:200–216

    PubMed  CAS  Google Scholar 

  133. Vittal, S.B.V., Dourdourekas, D., Steigmann, F.: Hepatitis-B antigen in saliva, urine and tears. Amer. J. Gastroenterol. 1974; 61: 133–135

    CAS  Google Scholar 

  134. Waters, J.A., Kennedy, M., Voet, P., Hauser, P., Petre, J., Carman, W., Thomas, H.C.: Loss of the common “a” determinant of hepatitis B surface antigen by a vaccine-induced escape mutant. J. Clin. Invest. 1992;90: 2543–2547

    PubMed  CAS  Google Scholar 

  135. Weber, H.C., Schoeman, J.F., Nowitz, A., Becker, M.L.B.: Case report: psychosis associated with hepatitis B. J. Med. Virol. 1994; 44: 5–8

    PubMed  CAS  Google Scholar 

  136. Weizsäcker, von, F., Puet, I., Geiss, K., Wirth, St., Blum, H.E.: Selective transmission of variant genomes from mother to infant in neonatal fulminant hepatitis B. Hepatology 1995; 21: 8–13

    Google Scholar 

  137. Welch, J., Tilzey, A.J., Webster, M., Noah, N.D., Banatvala, J.E.: Hepatitis B infections after gynaecological surgery. Lancet 1989; 1:205–206

    PubMed  CAS  Google Scholar 

  138. Williams, I., Smith, M.G., Sinha, D., Kernan, D., Minor-Babin, G., Garcia, E., Robertson, B.H., Di Pentima, R., Shapiro, C.N.: Hepatitis B virus transmission in an elementary school setting. J. Amer. Med. Ass. 1997; 278: 2167–2169

    CAS  Google Scholar 

  139. Wong, V.C.W., Ip, H.M.H., Reesink, H.W., Lelie, P.N., Reerink-Brongers, E.E., Yeung, C.Y., Ma, H.K.: Prevention of the HBsAg carrier state in newborn infants of mothers who are chronic carriers of HBsAg and HBeAg by administration of hepatitis-B vaccine and hepatitis-B immunoglobulin. Lancet 1984/I: 921–926

    Google Scholar 

  140. Wrzolkowa, T., Zurowska, A., Uszycka-Karcz, M., Picken, M.M.: Hepatitis B virus-associated glomerulonephritis: electron microscopic studies in 98 children. Amer. J. Kidn. Dis. 1991; 18: 306–312

    CAS  Google Scholar 

  141. Yao, E.M., Tavis, J.E.: Kinetics of synthesis and turnover of the duck hepatitis B virus reverse transcriptase. J. Biol. Chem. 2003; 278: 1201–1205

    PubMed  CAS  Google Scholar 

  142. Yotsumoto, S., Kojima, M., Shoji, I., Yamamoto, K., Okamoto, H., Mishiro, S.: Fulminant hepatitis related to transmission of hepatitis B variants with precore mutations between spouses. Hepatology 1992; 16: 31–35

    PubMed  CAS  Google Scholar 

  143. Young, B.W.Y., Lee, S.S., Lim, W.L., Yeoh, E.K.: The long-term efficacy of plasma-derived hepatitis B vaccine in babies born to carrier mothers. J. Viral Hepat. 2003; 10: 23–30

    CrossRef  PubMed  CAS  Google Scholar 

  144. Yuki, N., Nagaoka, T., Yamashiro, M., Mochizuki, K., Kaneko, A., Yamamoto, K., Omura, M., Hikiji, K., Kato, M.: Long-term histologic and virologic outcomes of acute self-limited hepatitis B. Hepatology 2003; 37: 1172–1179

    CrossRef  PubMed  CAS  Google Scholar 

  145. Zanetti, A.: Hepatitis B vaccination: an important method of preventing HBV-related hepatocellular carcinoma. Ital. J. Gastroenterol. 1992; 24: 100–102

    PubMed  CAS  Google Scholar 

  146. Zhu, Q.R., Yu, Q.J., Yu, H., Lu, Q., Gu, X.H., Dong, Z.Q., Zhang, X. Z.: A randomized control trial on interruption of HBV transmission in uterus. Chin. Med. J. 2003; 116: 685–687

    PubMed  Google Scholar 

  147. Zurn, A., Schmied, E., Saurat, J.-H.: Les manifestations cutanees de l’infection par le virus de l’hepatite B. Schweiz. Rundsch. Med. 1990; 79: 1254–1257

    CAS  Google Scholar 

Acute viral hepatitis C

  1. Ackerman, Z., Paltiel, O., Glikberg, F., Ackerman, E.: Hepatitis C virus in various human body fluids: a systematic review. Hepatol. Res. 1998; 11: 26–40

    Google Scholar 

  2. Agnello, V.: Mixed cryoglobulinemia and hepatitis C virus. Hospital Pract. 1995; 30: 35–42

    CAS  Google Scholar 

  3. Akahane, Y., Aikawa, T., Sugai, Y., Tsuda, F., Okamoto, H., Mishiro, S.: Transmission of HCV between spouses. Lancet 1992; 339:1059–1060

    CrossRef  PubMed  CAS  Google Scholar 

  4. Almasio, P., Provenzano, G., Scimemi, M., Cascio, G., Craxi, A., Pagliaro, L.: Hepatitis C virus and Sjögren’s syndrome. Lancet 1992; 339: 989–990

    CrossRef  PubMed  CAS  Google Scholar 

  5. Alter, M.J., Margolis, H.S., Krawczynski, K., Judson, F.N., Mares, A., Alexander, J., Hu, P.Y., Miller, J.K., Gerber, M.A., Sampliner, R.E., Meeks, E.L., Beach, M.J.: The natural history of community-acquired hepatitis C in the United States. New Engl. J. Med. 1992; 327: 1899–1905

    PubMed  CAS  Google Scholar 

  6. Arai, Y., Noda, K., Enomoto, N., Arai, K., Yamada, Y., Suzuki, K., Yoshihara, H.: A prospective study of hepatitis C virus infection after needlestick accidents. Liver 1996; 16: 331–334

    PubMed  CAS  Google Scholar 

  7. Bekkering, F.C., Brouwer, J.T., Leroux-Roels, G., van Vlierberghe, H., Elewaut, A., Schalm, S.W.: Ultrarapid hepatitis C virus clearance by daily high-dose interferon in non-responders to standard therapy. J. Hepatol. 1998; 28: 960–964

    PubMed  CAS  Google Scholar 

  8. Bhattacharya, R., Shuhart, M.C.: Hepatitis C and alcohol: interactions, outcomes, and implications. J. Clin. Gastroenterol. 2003; 36: 242–252

    CrossRef  PubMed  Google Scholar 

  9. Bisceglie, di A.M.: Hepatitis C and hepatocellular carcinoma. Semin. Liver Dis. 1995; 15: 64–69

    PubMed  Google Scholar 

  10. Bortolotti, F., Tagger, A., Cadrobbi, P., Crivellaro, C., Pregliasco, F., Ribero, M.L., Alberti, A.: Antibodies to hepatitis C virus in community-acquired acute non-A, non-B hepatitis. J. Hepatol. 1991; 12: 176–180

    CrossRef  PubMed  CAS  Google Scholar 

  11. Bresters, D., Mauser, F.M., Bunschoten, E.P., Reesink, H.W., Roosendaal, G., van der Poel, C.L., Chamuleau, R.A.M., Jansen, P.L.M., Weegink, C.J., Cuypers, H.T.M., van den Berg, H.M.: Sexual transmission of hepatitis C virus. Lancet 1993; 342: 210–211

    CrossRef  PubMed  CAS  Google Scholar 

  12. Brillanti, S., Foli, M., Gaiani, S., Masci, C., Miglioli, M., Barbara, L.: Persistent hepatitis C viraemia without liver disease. Lancet 1993; 341: 464–465

    CrossRef  PubMed  CAS  Google Scholar 

  13. Brown, J.L.: Hepatitis C: the structure and biology of the virus and diagnostic tests. J. Infect. 1995; 30: 95–101

    CrossRef  PubMed  CAS  Google Scholar 

  14. Bruguera, M., Saiz, J.C., Franco, S., Gimenez-Barcons, M., Sanchez-Tapias, J.M., Fabregas, S., Vega, R., Camps, N., Dominguez, A., Salleras, L.: Outbreak of nosocomial hepatitis C virus infection resolved by genetic analysis of HCV RNA. J. Clin. Microbiol. 2002; 40: 4363–4366

    CrossRef  PubMed  CAS  Google Scholar 

  15. Bukh, J., Miller, R.H., Purcell, R.H.: Genetic heterogeneity of hepatitis C virus: quasispecies and genotypes. Semin. Liver Dis. 1995; 15: 41–63

    PubMed  CAS  Google Scholar 

  16. Cacoub, P., Lunel-Fabiani, F., Huong Du, L.T.: Polyarteritis nodosa and hepatitis C virus infection. Ann. Intern. Med. 1992; 116: 605–606

    PubMed  CAS  Google Scholar 

  17. Carrozzo, M., Quadri, R., Latorre, P., Pentenero, M., Paganin, S., Bertolusso, G., Gandolfo, S., Negro, F.: Molecular evidence that the hepatitis C virus replicates in the oral mucosa. J. Hepatol. 2002; 37: 364–369

    CrossRef  PubMed  CAS  Google Scholar 

  18. Carson, C.W., Conn, D.L., Czaja, A.J., Wright, T.L., Brecher, M.E.: Frequency and significance of antibodies to hepatitis C virus in polyarteritis nodosa. J. Rheumatol. 1993; 20: 304–309

    PubMed  CAS  Google Scholar 

  19. Castells, L., Vargas, V., Gonzalez, A., Esteban, J., Esteban, R., Guardia, J.: Long interval between HCV infection and development of hepatocellular carcinoma. Liver 1995; 15: 159–163

    PubMed  CAS  Google Scholar 

  20. Chan, S.-W., McOmish, F., Holmes, E.C., Dow, B., Peutherer, J.F., Follett, E., Yap, P.-L., Simmonds, P.: Analysis of a new hepatitis C virus type and its phylogenetic relationship to existing variants. J. Gen. Virol. 1992; 73: 1131–1141

    PubMed  CAS  Google Scholar 

  21. Chang, M., Williams, O., Mittler, J., Quintanilla, A., Carithers, R.L., Perkins, J., Corey, L., Gretch, D.R.: Dynamics of hepatitis C virus replication in human liver. Amer. J. Path. 2003; 163: 433–444

    PubMed  CAS  Google Scholar 

  22. Chayama, K., Kobayashi, M., Tsubota, A., Koida, I., Arase, Y., Saitoh, S., Ikeda, K., Kumada, H.: Molecular analysis of intraspousal transmission of hepatitis C virus. J. Hepatol. 1995; 22: 431–439

    CrossRef  PubMed  CAS  Google Scholar 

  23. Chen, M.; Yun, Z.-B., Sällberg, M., Schvarcz, R., Bergquist, I., Berglund, H.-B., Sönnerborg, A.: Detection of hepatitis C virus RNA in the cell fraction of saliva before and after oral surgery. J. Med. Virol. 1995; 43: 223–226

    Google Scholar 

  24. Chu, C.-M., Liaw, Y.-F.: Simultaneous acute hepatitis B virus and hepatitis C virus infection leading to fulminant hepatitis and subsequent chronic hepatitis C. Clin. Infect. Dis. 1995; 20: 703–705

    PubMed  CAS  Google Scholar 

  25. Cody, S.H., Nainan, O.V., Garfein, R.S., Meyers, H., Bell, B.P., Shapiro, C.N., Meeks, E.L., Pitt, H., Mouzin, E., Alter, M.J., Margolis, H.S., Vugia, D:J.: Hepatitis C virus transmission from an anaesthesiologist to a patient. Arch. Intern. Med. 2002; 162: 345–350

    CrossRef  PubMed  CAS  Google Scholar 

  26. Daghestani, L., Pomeroy, C.: Renal manifestations of hepatitis C infection. Amer. J. Med. 1999; 106: 347–354

    PubMed  CAS  Google Scholar 

  27. Datz, C., Cramp, M., Haas, T., Dietze, O., Nitschko, H., Froesner, G., Muss, N., Sandhofer, F., Vogel, W.: The natural course of hepatitis C virus infection 18 years after an epidemic outbreak of non-A, non-B hepatitis in a plasmapheresis centre. Gut 1999; 44: 563–567

    PubMed  CAS  Google Scholar 

  28. Delage, G., Infante-Rivard, C., Chiavetta, J.A., Willems, B., Pi, D., Fast, M.: Risk factors for acquisition of hepatitis C virus infection in blood donors: results of a case-control study. Gastroenterology 1999; 116: 893–899

    CrossRef  PubMed  CAS  Google Scholar 

  29. Delarocque-Astagneau, E., Baffoy, N., Thiers, V., Simon, N., de Valk, H., Laperche, S., Courouce, A.M., Astagneau, P., Buisson, C., Desencios, J.C.: Outbreak of hepatitis C virus infection in a hemodialysis unit: Potential transmission by the hemodialysis machine? Infect. Contr. Hosp. Epidem. 2002; 23: 328–334

    Google Scholar 

  30. Devita, S., Zagonel, V., Russo, A., Rupolo, M., Cannizzaro, R., Chiara, G., Boiocchi, M., Carbone, A., Franceschi, S.: Hepatitis C virus, non-Hodgkin’s lymphomas and hepatocellular carcinoma. Brit. J. Canc. 1998; 77: 2032–2035

    CAS  Google Scholar 

  31. Dow, B.C., Follett, E.A.C., Jordan, T., McOmish, F., Davidson, J., Gillon, J., Yap, P.L., Simmonds, P.: Testing of blood donations for hepatitis C virus. Lancet 1994; 343: 477–478

    CrossRef  PubMed  CAS  Google Scholar 

  32. Dusheiko, G.M., Smith, M., Scheuer, P.J.: Hepatitis C virus transmitted by human bite. Lancet 1990; 336: 503–504

    CrossRef  PubMed  CAS  Google Scholar 

  33. El-Serag, H.B., Hampel, H., Yeh, C., Rabeneck, L.: Extrahepatic manifestations of hepatitis C among United States male veterans. Hepatology 2002; 36: 1439–1445

    CrossRef  PubMed  Google Scholar 

  34. Esteban, J.I., Lopez-Talavera, J.C., Genesca, J., Madoz, P., Viladomiu, L., Muniz, E., Martin-Vega, C., Rosell, M., Allende, H., Vidal, X., Gonzalez, A., Hernandez, J.M., Esteban, R., Guardia, J.: High rate of infectivity and liver disease in blood donors with antibodies to hepatitis C virus. Ann. Intern. Med. 1991; 115: 443–449

    PubMed  CAS  Google Scholar 

  35. Everhart, J.E., Di Bisceglie, A.M., Murray, L.M., Alter, H.J., Melpolder, J.J., Kuo, G., Hoofnagle, J.H.: Risk for non-A, non-B (type C) hepatitis through sexual or household contact with chronic carriers. Ann. Intern. Med. 1990; 112: 544–545

    PubMed  CAS  Google Scholar 

  36. Fagan, E.A., Partridge, M., Sowray, J.H., Williams, R.: Review of hepatitis non-A, non-B: the potential hazards in dental care. Oral Surg. 1988; 65: 167–171

    CrossRef  PubMed  CAS  Google Scholar 

  37. Fargion, S., Piperno, A., Capellini, M.D., Sampietro, M., Fracanzani, A.L., Romano, R., Caldarelli, R., Marcelli, R., Vecchi, L., Fiorelli, G.: Hepatitis C virus and porphyria cutanea tarda: evidence of a strong association. Hepatology 1992; 16: 1322–1323

    PubMed  CAS  Google Scholar 

  38. Feray, C., Gigou, M., Samuel, D., Paradis, V., Wilber, J., David, M.F., Urdea, M., Reynes, M., Brechot, C., Bismuth, H.: The course of hepatitis C virus infection after liver transplantation. Hepatology 1994; 20:1137–1143

    CrossRef  PubMed  CAS  Google Scholar 

  39. Fischler, B., Lindh, G., Lindgren, S., Forsgren, M., von Sydow, M., Sangfelt, P., Alaeus, A., Harland, L., Enockson, E., Nemeth, A.: Vertical transmission of hepatitis C virus infection. Scand. J. Infect. Dis. 1996; 28: 353–356

    PubMed  CAS  Google Scholar 

  40. Garcia-Bengoechea, M., Emparanza, J.I., Sarriugarte, A., Cortes, A., Vega, J.L., Gonzalez, F., Arenas, J.I.: Antibodies to hepatitis C virus: a cross-sectional study in patients attending a trauma unit or admitted to hospital for elective surgery. Eur. J. Gastroenterol. Hepatol. 1995; 7: 237–241

    PubMed  CAS  Google Scholar 

  41. Gerlach, J.T., Diepolder, H.M., Zachoval, R., Gruener, N.H., Jung, M.C., Ulsenheimer, A., Schraut, W.W., Schirren, C.A., Waechtler, M., Backmund, M., Pape, G.R.: Acute hepatitis C: High rate of both spontaneous and treatment induced viral clearance. Gastroenterology 2003; 125: 80–88

    CrossRef  PubMed  Google Scholar 

  42. Goetz, A.M., Ndimbie, O.K., Wagener, M.M., Muder, R.R.: Prevalence of hepatitis C infection in health care workers affiliated with a liver transplant center. Transplantation 1995; 59: 990–994

    PubMed  CAS  Google Scholar 

  43. Goodman, Z.D., Ishak, K.G.: Histopathology of hepatitis C virus infection. Semin. Liver Dis. 1995; 15: 70–81

    PubMed  CAS  Google Scholar 

  44. Gordon, F.D., Anastopoulos, H., Khettry, U., Loda, M., Jenkins, R.L., Lewis, W.D., Trey, C.: Hepatitis C infection: a rare cause of fulminant hepatic failure. Amer. J. Gastroenterol. 1995; 90: 117–120

    CAS  Google Scholar 

  45. Gordon, S.C., Bayati, N., Silverman, A.L.: Clinical outcome of hepatitis C as a function of mode of transmission. Hepatology 1998; 28:562–567

    PubMed  CAS  Google Scholar 

  46. Gordon, S.C.: New insights into acute hepatitis C. Gastroenterology 2003; 125: 253–256

    CrossRef  PubMed  Google Scholar 

  47. Grando-Lemaire, V., Goisset, P., Sorge, F., Trinchet, J.C., Castera, L., Roulot, D., Sitruk, V., Beaugrand, M.: Hepatitis C virus screening in drug users in an addiction out-patient unit. Gastroenterol. Clin. Biol. 2002; 26: 1091–1096

    PubMed  Google Scholar 

  48. Healey, C.J., Smith, D.B., Walker, J.L., Holmes, E.C., Fleming, K.A., Chapman, R.W.G., Simmonds, P.: Acute hepatitis C infection after sexual exposure. Gut 1995; 36: 148–150

    PubMed  CAS  Google Scholar 

  49. Hernandez, M.E., Bruguera, M., Puyuelo, T., Barrera, J.M., Sanchez Tapias, J.M., Rodes, J.: Risk of needle-stick injuries in the transmission of hepatitis C virus in hospital personnel. J. Hepatol. 1992; 16: 56–58

    CrossRef  PubMed  CAS  Google Scholar 

  50. Hinrichsen, H., Leimenstoll, G., Stegen, G., Schrader, H., Fölsch, U.R., Schmidt, W.E.: Prevalence and risk factors of hepatitis C virus infection in haemodialysis patients: a multicentre study in 2796 patients. Gut 2002; 51: 429–433

    CrossRef  PubMed  CAS  Google Scholar 

  51. Houghton, M., Weiner, A.J., Han, J., Kuo, G., Choo, Q.-L.: Molecular biology of the hepatitis C viruses: Implications for diagnosis, development and control of viral disease. Hepatology 1991; 14: 382–388

    CrossRef  Google Scholar 

  52. Jaeckel, E., Cornberg, M., Wedemeyer, H., Santantonio, T., Mayer, J., Zankel, M., Pastore, G., Dietrich, M., Trautwein, C., Manns, M.P.: Treatment of acute hepatitis C with interferone alfa-2b. New Engl. J. Med. 2001; 345: 1452–1457

    CrossRef  PubMed  CAS  Google Scholar 

  53. Kamal, S.M., Ismail, A., Graham, C.S., He, Q., Rasenack, J.W., Peters, T., Tawill, A.A., Fehr, J., Khalifa, K.E, Madwar, M.M., Koziel, M.J.: Pegylated interferon alpha therapy in acute hepatitis C: Relation to hepatitis C virus-specific T cell response kinetics. Hepatology 2004; 39: 1721–1731

    CrossRef  PubMed  CAS  Google Scholar 

  54. Kao, J.-H., Hwang, Y.-T., Chen, P.-J., Yang, P.-M., Lai, M.-Y., Wang, T.-H., Chen, D.-S.: Transmission of hepatitis C virus between spouses: the important role of exposure duration. Amer. J. Gastroenterol. 1996; 91: 2087–2090

    CAS  Google Scholar 

  55. Kenny-Walsh, E.: Clinical outcome after hepatitis C infection from contaminated anti-D immune globulin. New Engl. J. Med. 1999; 340: 1228–1233

    CrossRef  PubMed  CAS  Google Scholar 

  56. Kiyosawa, K., Sodeyama, T., Tanaka, E., Nakano, Y., Furuta, S., Nishioka, K., Purcell, R.H., Alter, H.J.: Hepatitis C in hospital employees with needlestick injuries. Ann. Intern. Med. 1991; 115: 367–369

    PubMed  CAS  Google Scholar 

  57. Klein, R.S., Freeman, K., Taylor, P.E., Stevens, C.E.: Occupational risk for hepatitis C virus infection among New York City dentists. Lancet 1991; 338: 1539–1542

    CrossRef  PubMed  CAS  Google Scholar 

  58. Kobayashi, K., Hashimoto, E., Ludwig, J., Hisamitsu, T., Obata, H.: Liver biopsy features of acute hepatitis C compared with hepatitis A, B, and non-A, non-B, non-C. Liver 1993; 13: 69–72

    PubMed  CAS  Google Scholar 

  59. Kodama, T., Tamaki, T., Katabami, S., Katamuma, A., Yamashita, K., Azuma, N., Kamijo, K., Kinoshita, H., Yachi, A.: Histological findings in asymptomatic hepatitis C virus carriers. J. Gastroenterol. Hepatol. 1993; 8: 403–405

    PubMed  CAS  Google Scholar 

  60. Kong, M.-S., Chung, J.-L.: Fatal hepatitis C in an infant born to a hepatitis C positive mother. J. Pediatr. Gastroenterol. Nutrit. 1994; 19: 460–463

    CAS  Google Scholar 

  61. König, V., Bauditz, J., Lobeck, H., Lüsebrink, R., Neuhaus, P., Blumhardt, G., Bechstein, W.O., Neuhaus, R., Steffen, R., Hopf, U.: Hepatitis C virus reinfection in allografts after orthotopic liver transplantation. Hepatology 1992; 16: 1137–1143

    PubMed  Google Scholar 

  62. Krause, G., Trepka, M.J., Whisenhunt, R.S., Katz, D., Nainan, O., Wiersma, S.T., Hopkins, R.S.: Nosocomial transmission of hepatitis C virus associated with the use of multidose saline vials. Infect. Contr. Hosp. Epidem. 2003; 24: 122–127

    Google Scholar 

  63. Kumar, R.M., Shahul, S.: Role of breast-feeding in transmission of hepatitis C virus to infants of HCV-infected mothers. J. Hepatol. 1998; 29: 191–197

    CrossRef  PubMed  CAS  Google Scholar 

  64. Kuo, G., Choo, Q.L., Alter, H.J., Gitnick, G.L., Redeker, A.G., Purcell, R.H., Miyamura, T., Dienstag, J.L., Alter, M.J., Stevens, C.E., Tegtmeier, G.E., Bonino, F., Colombo, M., Lee, W.-S., Kuo, C., Berger, K., Shuster, J.R., Overby, L.R., Bradley, D.W., Houghton, M.: An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis. Science 1989; 244: 362–364

    PubMed  CAS  Google Scholar 

  65. Lacaille, F., Zylberberg, H., Hagége, H., Roualdés, B., Meyrignac, C., Chousterman, M., Girot, R.: Hepatitis C associated with Guillain-Barré syndrome. Liver 1998; 18: 49–51.

    PubMed  CAS  Google Scholar 

  66. Larglu, A., Zuin, M., Crosignani, A., Ribero, M.L., Pipia, C., Battezzati, P.M., Binelli, G., Donato, F., Zanetti, A.R., Podda, M., Tagger, A.: Outcome of an outbreak of acute hepatitis C among healthy volunteers participating in pharmacokinetics studies. Hepatology 2002; 36: 963–1000

    Google Scholar 

  67. Lauer, G.M., Walker, B.D.: Hepatitis C virus infection. New Engl. J. Med. 2001; 354: 41–52

    Google Scholar 

  68. Le Pogam, S., Le Chapois, D., Christen, R., Dubois, F., Barin, F., Goudeau, A.: Hepatitis C in a hemodialysis unit: molecular evidence for nosocomial transmission. J. Clin. Microbiol. 1998; 36: 3040–3043

    PubMed  Google Scholar 

  69. Lee, H.-S., Han, C.J., Kim, C.Y.: Predominant etiologic association of hepatitis C virus with hepatocellular carcinoma compared with hepatitis B virus in elderly patients in a hepatitis B-endemic area. Cancer 1993; 72: 2564–2567

    PubMed  CAS  Google Scholar 

  70. Lieber, C.S.: Hepatitis C and alcohol. J. Clin. Gastroenterol. 2003; 36: 100–102

    CrossRef  PubMed  Google Scholar 

  71. Liou, T.C., Chang, T.T., Young, K.C., Lin, X.Z., Lin, C.Y., Wu, H.L.: Detection of HCV RNA in saliva, urine, seminal fluid, and ascites. J. Med. Virol. 1992; 37: 197–202

    PubMed  CAS  Google Scholar 

  72. Loustaud-Ratti, V., Liozon, E., Karaaslan, H., Alain, S., le Meur, Y., Denis, F., Vidal, E.: Interferon alpha and ribavirin for membranoproliferative glomerulonephritis and hepatitis C infection. Amer. J. Med. 2002; 113: 516–519

    PubMed  CAS  Google Scholar 

  73. Macedo, G., Correia, A., Ribeiro, T.: Antiviral treatment in acute hepatitis C. Hepato-Gastroenterol. 2003; 50: 1057–1059

    CAS  Google Scholar 

  74. Maggi, F., Vatteroni, M.L., Pistello, M., Avio, C.M., Cecconi, N., Panicucci, F., Bendinelli, M.: Serological reactivity and viral genotypes in hepatitis C virus infection. J. Clin. Microbiol. 1995; 33: 209–211

    PubMed  CAS  Google Scholar 

  75. Major, M.E., Feinstone, S.M.: The molecular virology of hepatitis C. Hepatology 1997; 25: 1527–1538

    CrossRef  PubMed  CAS  Google Scholar 

  76. Manavi, M., Baghestanian, M., Watkins-Riedel, T., Battistutti, W., Pischinger, K., Schatten, C., Witschko, E., Hudelist, G., Hofmann, H., Czerwenka, K.: Detection of hepatitis C virus (HCV) RNA in normal cervical smears of HCV-seropositive patients. Clin. Infect. Dis. 2002; 35: 966–973

    CrossRef  PubMed  CAS  Google Scholar 

  77. Mansell, C.J., Locarnini, S.A.: Epidemiology of hepatitis C in the East. Semin. Liver Dis. 1995; 15: 15–32

    PubMed  CAS  Google Scholar 

  78. Marzano, A., Smedile, A., Abate, M., Ottobrelli, A., Brunetto, M., Negro, F., Farci, P., Durazzo, M., David, E., Lagget, M., Verme, G., Bonino, F., Rizzetto, M.: Hepatitis type C after orthotopic liver transplantation: reinfection and disease recurrence. J. Hepatol. 1994; 21: 961–965

    CrossRef  PubMed  CAS  Google Scholar 

  79. Mazzaro, C., Efremov, D.G., Burrone, O., Pozzato, G.: Hepatitis C virus; mixed cryoglobulinaemia and non-Hodgkin’s lymphoma. Ital. J. Gastroenterol. Hepatol. 1998; 30: 428–434

    PubMed  CAS  Google Scholar 

  80. Meisel, H., Reip, A., Faltus, B., Lu, M., Porst, H., Wiese, M., Roggendorf, M., Krüger, D.H.: Transmission of hepatitis C virus to children and husbands by women infected with contaminated anti-D immunoglobulin. Lancet 1995; 345: 1209–1211

    CrossRef  PubMed  CAS  Google Scholar 

  81. Melbye, M., Biggar, R.J., Wantzin, P., Krogsgaard, K., Ebbesen, P., Becker, N.G.: Sexual transmission of hepatitis C virus: cohort study (1981–9) among European homosexual men. Brit. Med. J. 1990; 301: 210–212

    PubMed  CAS  Google Scholar 

  82. Memon, M.I., Memon, M.A.: Hepatitis C: An epidemiological review. J. Viral Hepat. 2002; 9: 84–100

    CrossRef  PubMed  CAS  Google Scholar 

  83. Michielsen, P., Brenard, R., Bourgeois, N., de Galocsy, C., Delwaide, J., Henrion, J., Horsmans, Y., Nevens, F., Reynaert, H., Robaeys, G., Sprengers, D., van Vlierberghe, H.: Hepatitis C: screening, treatment and prevention practical guidelines. Acta Gastro-Enterol. Belg. 2003; 66: 15–19

    CAS  Google Scholar 

  84. Misiani, R., Bellavita, P., Fenili, D., Vicari, O., Marchesi, D., Sironi, P.L., Zilio, P., Vernocchi, A., Massazza, M., Vendramin, G., Tanzi, E., Zanetti, A.: Interferon alfa-2a therapy in cryoglobulinemia associated with hepatitis C virus. New Engl. J. Med. 1994; 330: 751–756

    CrossRef  PubMed  CAS  Google Scholar 

  85. Mitsui, T., Iwano, K., Masuko, K., Yamazaki, C., Okamoto, H., Tsuda, F., Tanaka, T., Mishiro, S.: Hepatitis C virus infection in medical personnel after needlestick accident. Hepatology 1992; 16: 1109–1114

    CrossRef  PubMed  CAS  Google Scholar 

  86. Moller, J.M., Krarup, H.B.: Diagnosis of acute hepatitis C: Anti-HCV or HCV-RNA? Scand. J. Gastroenterol. 2003; 38: 556–558

    PubMed  CAS  Google Scholar 

  87. Morin, T., Pariente, A.: Acute hepatitis C: A retrospective study of 62 cases. Gastroenterol. Clin. Biol. 2002; 26: 994–1000

    PubMed  Google Scholar 

  88. Müller, H.M., Pfaff, E., Goeser, T., Kallinowski, B., Solbach, C., Theilmann, L.: Peripher blood leukocytes serve as a possible extrahepatic site for hepatitis C virus replication. J. Gen. Virol. 1993; 74: 669–676

    PubMed  Google Scholar 

  89. Murphy, A., Dooly, S., Hillary, I.B., Murphy, G.M.: HCV infection in porphyria cutanea tarda. Lancet 1993; 341: 1534–1535

    PubMed  CAS  Google Scholar 

  90. Nocente, R., Ceccanti, M., Bertazzoni, G., Cammarota, G., Gentiloni-Silveri, N., Gasbarrini, G.: HCV infection and extrahepatic manifestations. Hepato-Gastroenterol. 2003; 50: 1149–1154

    Google Scholar 

  91. Orland, J.R., Wright, T.L., Cooper, S.: Acute hepatitis C. Hepatology 2001; 33: 321–327

    CrossRef  PubMed  CAS  Google Scholar 

  92. Palitzsch, K.-D., Hottenträger, B., Schlottmann, K., Frick, E., Holstege, A., Schölmerich, J., Jilg, W.: Prevalence of antibodies against hepatitis C virus in the adult German population. Eur. J. Gastroenterol. Hepatol. 1999; 11: 1215–1220

    PubMed  CAS  Google Scholar 

  93. Peano, G.M., Fenoglio, L.M., Menardi, G., Balbo, R., Marenchino, D., Fenoglio, S.: Heterosexual transmission of hepatitis C virus in family groups without risk factors. Brit. Med. J. 1992; 305: 1473–1474

    PubMed  CAS  Google Scholar 

  94. Perez-Calvo, J., Lasierra, P., Moros, M., Inigo, P.: Role of ribavirin in membranoproliferative glomerulonephritis associated with hepatitis C virus infection refractory to alpha-interferon. Nephron 2002; 92: 459–462

    PubMed  Google Scholar 

  95. Persico, M., Romano, M.: Alanine aminotransferase measurements and histological disease in hepatitis C. Lancet 1993; 342: 1369–1370

    CrossRef  PubMed  CAS  Google Scholar 

  96. Peters, M.G., Terrault, N.A.: Alcohol use and hepatitis C. Hepatology 2002; 36(Suppl.): 220–225

    Google Scholar 

  97. Pilli, M., Penna, A., Zerbini, A., Vescovi, P., Manfredi, M., Negro, F., Carrozzo, M., Mori, C., Giuberti, T., Ferrari, C., Missale, G.: Oral lichen planus pathogenesis: A role for the HCV-specific cellular immune response. Hepatology 2002; 36: 1446–1452

    CrossRef  PubMed  CAS  Google Scholar 

  98. Puoti, C., Guido, M., Mangia, A., Persico, M., Prati, D.: Clinical management of HCV carriers with normal aminotransferase levels. Dig. Liv. Dis. 2003; 35: 362–369

    CAS  Google Scholar 

  99. Quint, L., Deny, P., Guillevin, L., Granger, B., Jarrousse, B., Lhote, F., Scavizzi, M.: Hepatitis C virus in patients with polyarteritis nodosa. Prevalence in 38 patients. Clin. Experim. Rheumatol. 1991; 9: 253–257

    CAS  Google Scholar 

  100. Resti, M., Azzari, C., Lega, L., Rossi, M.E., Zammarchi, E., Novembre, E., Vierucci, A.: Mother-to-infant transmission of hepatitis C virus. Acta Paediatr. 1995; 84: 251–255

    PubMed  CAS  Google Scholar 

  101. Resti, M., Jara, P., Hierro, L., Azzari, C., Giacchino, R., Zuin, G., Zancan, L., Pedditzi, S., Bortolotti, F.: Clinical features and progression of perinatally acquired hepatitis C virus infection. J. Med. Virol. 2003; 70: 373–377

    CrossRef  PubMed  Google Scholar 

  102. Rey, J.-F., Halfon, P., Feryn, J.-M., Khiri, H., Masseyeff, M.-F., Ouzan, D.: Risque de transmission du virus de l’hepatite C par l’endoscopie digestive. Gastroenterol. Clin. Biol. 1995; 19: 346–349

    PubMed  CAS  Google Scholar 

  103. Rice, P.S., Smith, D.B., Simmonds, P., Holmes, E.: Heterosexual transmission of hepatitis C virus. Lancet 1993; 342: 1052–1053

    CrossRef  PubMed  CAS  Google Scholar 

  104. Rocca, P., Bailly, F., Chevallier, M., Chevallier, P., Zoulim, F., Trepo, C.: Early treatment of acute hepatitis C with interferon alpha-2b or interferon alpha-2b plus ribavirin: study of sixteen patients. Gastroenterol. Clin. Biol. 2003; 27: 294–299

    PubMed  Google Scholar 

  105. Rollino, C., Roccatello, D., Giachino, O., Basolo, B., Piccoli, G.: Hepatitis C virus infection and membraneous glomerulonephritis. Nephron 1991; 59: 319–320

    PubMed  CAS  Google Scholar 

  106. Ross, R.S., Viazov, S., Thormahlen, M., Bartz, L., Tamm, J., Rautenberg, P., Roggendorf, M., Deisler, A.: Risk of hepatitis C virus transmission from an infected gynecologist to patients. Results of a 7-year retrospective investigation. Arch. Intern. Med. 2002; 162: 805–810

    CrossRef  PubMed  Google Scholar 

  107. Saito, I., Miyamura, T., Ohbayashi, A., Harada, H., Katayama, T., Kikuchi, S., Watanabe, Y., Koi, S., Onji, M., Ohta, Y., Choo, Q.L., Houghton, M., Kuo, G.: Hepatitis C virus infection is associated with the development of hepatocellular carcinoma. Proc. Nat. Acad. Sci. USA 1990; 87: 6547–6549

    PubMed  CAS  Google Scholar 

  108. Santantonio, T., Sinisi, E., Guastadisegni, A., Casalino, C., Mazzola, M., Gentile, A., Leandro, G., Pastore, G.: Natural course of acute hepatitis C: A long-term prospective study. Dig. Liv. Dis. 2003; 35: 104–113

    CAS  Google Scholar 

  109. Scheuer, P.J., Ashrafzadeh, P., Sherlock, S., Brown, D., Dusheiko, G.M.: The pathology of hepatitis C. Hepatology 1992; 15: 567–571

    PubMed  CAS  Google Scholar 

  110. Schiff, E.R., de Medina, M., Kahn, R.S.: New perspectives in the diagnosis of hepatitis C. Semin. Liver Dis. 1999; 19(Suppl. 1) 3–15

    PubMed  Google Scholar 

  111. Schlipkoter, U., Roggendorf, M., Cholmakow, K., Weise, A., Deinhardt, F.: Transmission of hepatitis C virus (HCV) from a haemodialysis patient to a medical staff member. Scand. J. Infect. Dis. 1990; 22: 757–758

    PubMed  CAS  Google Scholar 

  112. Seeff, L.B., Miller, R.N., Rabkin, C.S., Buskell-Bales, Z., Straley-Eason, K.D., Smoak, B.L., Johnson, L.D., Lee, S.R., Kaplan, E.L.: 45-year follow-up of hepatitis C virus infection in healthy young adults. Ann. Intern. Med. 2000; 132: 105–111

    PubMed  CAS  Google Scholar 

  113. Seeff, L.B.: Natural history of viral hepatitis, type C. Semin. Gastrointest. Dis. 1995; 6: 20–27

    PubMed  CAS  Google Scholar 

  114. Shiffman, M.L., Contos, M.J., Luketic, V.A., Sanyal, A.S., Purdum III, P.P., Mills, A.S., Fisher, R.A., Posner, M.P.: Biochemical and histologic evaluation of recurrent hepatitis C following orthotopic liver transplantation. Transplantation 1994; 57: 526–532

    PubMed  CAS  Google Scholar 

  115. Silini, E., Bono, F., Cividini, A., Cerino, A., Maccabruni, A., Tinelli, C., Bruno, S., Bellobuono, A., Mondelli, M.U.: Molecular epidemiology of hepatitis C virus infection among intravenous drug users. J. Hepatol. 1995; 22: 691–695

    CrossRef  PubMed  CAS  Google Scholar 

  116. Simmonds, P.: Variability of hepatitis C virus. Hepatology 1995; 21: 570–583

    CrossRef  PubMed  CAS  Google Scholar 

  117. Stanley, A.J., Haydon, G.H., Piris, J., Jarvis, L.M., Hayes, P.C.: Assessment of liver histology in patients with hepatitis C and normal transaminase levels. Eur. J. Gastroenterol. Hepatol. 1996; 8: 869–872

    PubMed  CAS  Google Scholar 

  118. Steininger, C., Kundi, M., Jatzko, G., Kiss, H., Lischka, A., Holzmann, H.: Increased risk of mother-to-infant transmission of hepatitis C virus by intrapartum infantile exposure to maternal blood. J. Infect. Dis. 2003; 187: 345–351

    CrossRef  PubMed  Google Scholar 

  119. Stevens, C.E., Taylor, P.E., Pindyck, J., Choo, Q.-L., Bradley, D.W., Kuo, G., Houghton, M.: Epidemiology of hepatitis C virus. A preliminary study in volunteer blood donors. J. Amer. Med. Ass. 1990; 263: 49–53

    CAS  Google Scholar 

  120. Stölzel, U., Köstler, E., Koszka, C., Stöffler-Meilicke, M., Schuppan, D., Somasundaram, R., Doss, M.O., Habermehl, K.O., Riecken, E.O.: Low prevalence of hepatitis C virus infection in porphyria cutanea tarda in Germany. Hepatology 1995; 21: 1500–1503

    PubMed  Google Scholar 

  121. Sulkowski, M.S., Ray, S.C., Thomas, D.L.: Needlestick transmission of hepatitis C. J. Amer. Med. Ass. 2002; 287: 2406–2413

    Google Scholar 

  122. Takada, N., Takase, S., Takada, A., Date, T.: Differences in the hepatitis C virus genotypes in different countries. J. Hepatol. 1993; 17: 277–283

    CrossRef  PubMed  CAS  Google Scholar 

  123. Tallis, G.F., Ryan, G.M., Lambert, S.B., Bowden, D.S., McCaw, R., Birch, C.J., Moloney, M., Carnie, J.A., Locarnini, S.A., Rouch, G.J., Catton, M.G.: Evidence of patient-to-patient transmission of hepatitis C virus through contaminated intravenous anaesthetic ampoules. J. Viral Hepat. 2003; 10: 234–239

    CrossRef  PubMed  CAS  Google Scholar 

  124. Tedder, R.S., Gilson, R.J.C., Briggs, M., Loveday, C., Cameron, C.H., Garson, J.A., Kelly, G.E., Weller, S.V.D.: Hepatitis C virus: evidence for sexual transmission. Brit. Med. J. 1991; 302: 1299–1302

    PubMed  CAS  Google Scholar 

  125. Theilmann, L., Solbach, C., Toex, U., Müller, H.M., Pfaff, E., Otto, G., Goeser, T.: Role of hepatitis C virus in German patients with fulminant and subfulminant hepatic failure. Eur. J. Clin. Invest. 1992; 22: 569–571

    PubMed  CAS  Google Scholar 

  126. Thimme, R., Oldach, D., Chang, K.-M., Steiger, C., Ray, S.C., Chisari, F.V.: Determinants of viral clearance and persistence during acute hepatitis C virus infection. J. Exper. Med. 2001; 194: 1395–1406

    CrossRef  CAS  Google Scholar 

  127. Thomas, D.L., Zenilman, J.M., Alter, H.J., Shih, J.W., Galai, N., Carella, A.V., Quinn, T.C.: Sexual transmission of hepatitis C virus among patients attending Sexually Transmitted Diseases Clinics in Baltimore. An analysis of 309 sex partnerships. J. Infect. Dis. 1995; 171: 768–775

    PubMed  CAS  Google Scholar 

  128. Thorburn, D., Roy, K., Cameron, S.O., Johnston, J., Hutchinson, S., McCruden, E.A.B., Mills, P.R., Goldberg, D.J.: Risk of hepatitis C virus transmission from patients to surgeons: Model based on an unlinked anonymous study of hepatitis C virus prevalence in hospital patients in Glasgow. Gut 2003; 52: 1333–1338

    PubMed  CAS  Google Scholar 

  129. Tong, M.J., El-Farra, N.S., Reikes, A.R., Co, R.L.: Clinical outcomes after transfusion-associated hepatitis C. New Engl. J. Med. 1995; 332: 1463–1466

    CrossRef  PubMed  CAS  Google Scholar 

  130. Tumminelli, F., Marcellin, P., Rizzo, S., Barbera, S., Corvino, G., Furta, P., Benhamou, J.-P., Erlinger, S.: Shaving as potential source of hepatitis C virus infection. Lancet 1995; 345: 658.

    CrossRef  PubMed  CAS  Google Scholar 

  131. Utsumi, T., Hashimoto, E., Okumura, Y., Takayanagi, M., Nishikawa, H., Kigawa, M., Kumakura, N., Toyokawa, H.: Heterosexual activity as a risk factor for the transmission of hepatitis C virus. J. Med. Virol. 1995; 46: 122–125

    PubMed  CAS  Google Scholar 

  132. Vaglia, A., Nicolin, R., Puro, V., Ippolito, G., Bettini, C., de Lalla, F.: Needlestick hepatitis C virus seroconversion in a surgeon. Lancet 1990; 336: 1315–1316

    CrossRef  Google Scholar 

  133. Weinstein, J.S., Poterucha, J.J., Zein, N., Wiesner, R.H., Persing, D.H., Rakela, J.: Epidemiology and natural history of hepatitis C infections in liver transplant recipients. J. Hepatol. 1995; 22(Suppl. 1): 154–159

    PubMed  CAS  Google Scholar 

  134. Wilson, S.E., Lee, W.M., Murakami, C., Weng, J., Moninger, G.A.: Mooren’s corneal ulcers and hepatitis C virus infection. New Engl. J. Med. 1993; 329: 62.

    PubMed  CAS  Google Scholar 

  135. Wright, T.L., Donegan, E., Hsu, H.H., Ferrell, L., Lake, J.R., Kim, M., Combs, C., Fennessy, S., Roberts, J.P., Ascher, N.L., Greenberg, H.B.: Recurrent and acquired hepatitis C viral infection in liver transplant recipients. Gastroenterology 1992; 103: 317–322

    PubMed  CAS  Google Scholar 

  136. Yoffe, B., Bagri, A.S., Tran, T., Dural, A.T., Shtenberg, K.M., Khaoustov, V.I.: Hyperlipasemia associated with hepatitis C virus. Dig. Liv. Sci. 2003; 48: 1648–1653

    Google Scholar 

  137. Zaaijer, H.L., Cuypers, H.T.M., Reesink, H.W., Winkel, I.N., Gerken, G., Lelie, P.N.: Reliability of polymerase chain reaction for detection of hepatitis C virus. Lancet 1993; 341: 722–724

    PubMed  CAS  Google Scholar 

  138. Zanetti, A.R., Tanzi, E., Romano, L., Zuin, G., Minola, E., Vecchi, L., Principi, N.: A prospective study on mother-to-infant transmission of hepatitis C virus. Intervirology 1998; 41: 208–212

    CrossRef  PubMed  CAS  Google Scholar 

  139. Zhang, W.H., Liu, Ch.B., Sun, Y.D., Alter, H.J., Shih, J.W.-K.: Hepatitis C virus causing non-A, non-B hepatitis in plasmapheresis centre. Lancet 1990; 335: 353.

    CrossRef  PubMed  CAS  Google Scholar 

  140. Zuckerman, J., Clewley, G., Griffiths, P., Cockcroft, A.: Prevalence of hepatitis C antibodies in clinical health-care workers. Lancet 1994; 343: 1618–1620

    PubMed  CAS  Google Scholar 

Acute viral hepatitis D

  1. Amarapurkar, D.N., Vishwanath, N., Kumar, A., Shankaran, S., Murti, P., Kalro, R.H., Desai, H.G.: Prevalence of delta virus infection in high risk population and hepatitis B virus related liver diseases. Ind. J. Gastroenterol. 1992; 11: 11–12

    CAS  Google Scholar 

  2. Battegay, M., Simpson, L.H., Hoofnagle, J.H., Sallie, R., Di Bisceglie, A.M.: Elimination of hepatitis delta virus infection after loss of hepatitis B surface antigen in patients with chronic delta hepatitis. J. Med. Virol. 1994; 44: 389–392

    PubMed  CAS  Google Scholar 

  3. Bichko, V., Netter, H.J., Wu, T.-T., Taylor, J.: Pathogenesis associated with replication of hepatitis delta virus. Infect. Agents Dis. 1994; 3: 94–97

    PubMed  CAS  Google Scholar 

  4. Bordier, B.B., Marion, P.L., Ohashi, K., Kay, M.A., Greenberg, H.B., Casey, J.L., Glenn, J.S.: A prenylation inhibitor prevents production of infectious hepatitis delta virus particles. J. Virol. 2002; 76: 10465–10472

    CrossRef  PubMed  CAS  Google Scholar 

  5. Buitrago, B., Popper, H., Hadler, S.C., Thung, S.N., Gerber, M.A., Purcell, R.H., Maynard, J.E.: Specific histologic features of Santa Marta hepatitis: a severe form of hepatitis δ-virus infection in Northern South America. Hepatology 1986; 6: 1285–1291

    PubMed  CAS  Google Scholar 

  6. Caredda, F., Rossi, E., D’Arminio Monforte, A.: An outbreak of delta agent among a group of drug addicts and their close contacts. J. Infect. Dis. 1984; 149: 286–287

    PubMed  CAS  Google Scholar 

  7. Carreno, V., Bartolome, J., Madejon, A.: Hepatitis delta virus infection: molecular biology and treatment. Dig. Dis. 1994; 12: 265–275

    PubMed  CAS  Google Scholar 

  8. Chen, P.-J., Kalpana, G., Goldberg, J., Mason, W., Werner, B., Gerin, J.L., Taylor, J.: Structure and replication of the genome of the hepatitis delta virus. Proc. Nat. Acad. Sci. USA 1986; 83: 8874–8878

    Google Scholar 

  9. Colombo, P., Di Blasi, F., Magrin, S., Fabiano, C., Di Marco, V., D’Amelio, L., Lojacono, F., Spinelli, G., Craxi, A.: Smouldering hepatitis B virus replication in patients with chronic liver disease and hepatitis delta virus superinfection. J. Hepatol. 1991; 12: 64–69

    CrossRef  PubMed  CAS  Google Scholar 

  10. Craxi, A., TinŁ, F., Vinci, M., Almasio, P., Camma, C., Garofalo, G., Pagliaro, L.: Transmission of hepatitis B and hepatitis delta viruses in the households of chronic hepatitis B surface antigen carriers: a regression analysis of indicators of risk. Amer. J. Epidem. 1991; 134: 641–650

    CAS  Google Scholar 

  11. Davies, S.E., Lau, J.Y.N., O’Grady, J.G., Portmann, B.C., Alexander, G.J.M., Williams, R.: Evidence that hepatitis D virus needs hepatitis B virus to cause hepatocellular damage. Amer. J. Clin. Path. 1992; 98: 554–558

    CAS  Google Scholar 

  12. Desai, P., Banker, D.D.: Hepatitis B and delta viruses in fulminant hepatitis. Ind. J. Gastroenterol. 1990; 9: 209–210

    CAS  Google Scholar 

  13. Erhardt, A., Knuth, R., Sagir, A., Kirschberg, O., Heintges, T., Häussinger, D.: Socioepidemiological data on hepatitis delta in a German University Clinic-increase in patients from Eastern Europe and the Former Soviet Union. Zschr. Gastroenterol. 2003; 41: 523–526

    CAS  Google Scholar 

  14. Farci, P.: Delta hepatitis: an update. J. Hepatol. 2003; 39(S): 212–219

    Google Scholar 

  15. Foster, G.R., Carman, W.F., Thomas, H.C.: Replication of hepatitis B and delta viruses: appearance of viral mutants. Semin. Liver Dis. 1991; 11: 121–127

    PubMed  CAS  Google Scholar 

  16. Govindarajan, S., De Cok, K.M., Redeker, A.G.: Natural course of delta superinfection in chronic hepatitis B virus-infected patients: histopathologic study with multiple liver biopsies. Hepatology 1986; 6: 640–644

    PubMed  CAS  Google Scholar 

  17. Gupta, S., Govindarajan, S., Cassidy, W.M., Valinluck, B., Redeker, A.G.: Acute delta hepatitis: serological diagnosis with particular reference to hepatitis delta virus RNA. Amer. J. Gastroenterol. 1991; 86: 1227–1231

    CAS  Google Scholar 

  18. Hadler, S.C., De Monzon, M., Ponzetto, A., Anzola, E., Rivero, D., Mondolfi, A., Bracho, A., Francis, D.P., Gerber, M.A., Thung, S., Gerin, J., Maynard, J.E., Popper, H., Purcell, R.H.: Delta virus infection and severe hepatitis. An epidemic in the Yucpa Indians of Venezuela. Ann. Intern. Med. 1984; 100: 339–444

    PubMed  CAS  Google Scholar 

  19. Hsu, S.C., Syu, W.J., Sheen, I.J., Liu, H.T., Jeng, K.S., Wu, J.C.: Varied assembly and RNA editing efficiencies between genotypes I and II hepatitis D virus and their implications. Hepatology 2002; 35: 665–672

    PubMed  CAS  Google Scholar 

  20. Jardi, R., Buti, M., Cotrina, M., Rodriguez, F., Allende, H., Esteban, R., Guardia, J.: Determination of hepatitis delta virus RNA by polymerase chain reaction in acute and chronic delta infection. Hepatology 1995; 21: 25–29

    CrossRef  PubMed  CAS  Google Scholar 

  21. Lai, M.M.C., Lee, C.-M., Bih, F.-Y., Govindarajan, S.: The molecular basis of heterogeneity of hepatitis delta virus. J. Hepatol. 1991; 13(Suppl. 4): 121–124

    Google Scholar 

  22. Lettau, L.A., McCarthy, J.G., Smith, M.H., Hadler, St.C., Morse, L.J., Ukena, T., Bessette, R., Gurwitz, A., Irvine, W.G., Fields, H.A., Grady, G.F., Maynard, J.E.: Outbreak of severe hepatitis due to delta and hepatitis B viruses in parenteral drug abusers and their contacts. New Engl. J. Med. 1987; 317: 1256–1262

    PubMed  CAS  Google Scholar 

  23. Liaw, Y.-F., Chen, T.-J., Chu, C.-M., Lin, H.-H.: Acute hepatitis delta virus superinfection in patients with liver cirrhosis. J. Hepatol. 1990; 10: 41–45

    CrossRef  PubMed  CAS  Google Scholar 

  24. Lucey, M.R., Graham, D.M., Martin, P., Di Bisceglie, A., Rosenthal, S., Waggoner, J.G., Merion, R.M., Campbell, D.A., Nostrant, T.T., Appelman, H.D.: Recurrence of hepatitis B and delta hepatitis after orthotopic liver transplantation. Gut 1992; 33: 1390–1396

    PubMed  CAS  Google Scholar 

  25. Manesis, E., Zoumboulis, P., Georgiou, S., Vardaka, J., Hadziyannis, St.: Splenomegaly in asymptomatic chronic carriers of hepatitis B and D viruses. Eur. J. Gastroenterol. Hepatol. 1994; 6: 793–796

    Google Scholar 

  26. Mas, A., Buti, M., Esteban, R., Sanchez-Tapias, J.M., Costa, J., Jardi, R., Bruguera, M., Guardia, J., Rodes, J.: Hepatitis B virus and hepatitis D virus replication in HBsAg-positive fulminant hepatitis. Hepatology 1990; 11: 1062–1065

    PubMed  CAS  Google Scholar 

  27. Mendez, L., Reddy, K.R., Di Prima, R.A., Jeffers, L.J., Schiff, E.R.: Fulminant hepatic failure due to acute hepatitis B and delta co-infection: probable bloodborne transmission associated with a springloaded fingerstick device. Amer. J. Gastroenterol. 1991; 86: 895–897

    CAS  Google Scholar 

  28. Mentha, G., Giostra, E., Perrin, L., Widmann, J.J., Stelling, M.J., Easton, J., Morel, P., Huber, D., Le Coultre, C., Bühler, L., Rohner, A.: Prevention de la recidive virale aprŁs transplantation hepatique pour cirrhose post-hepatitique B et B-Delta. Schweiz. Med. Wschr. 1994; 124: 637–641

    PubMed  CAS  Google Scholar 

  29. Moraleda, G., Bartolome, J., Martinez, M.G., Porres, J.C., Carreno, V.: Influence of hepatitis delta virus replication in the presence of hepatitis B virus DNA in peripheral blood mononuclear cells. Hepatology 1990; 12: 1290–1294

    PubMed  CAS  Google Scholar 

  30. Negro, F., Rizzetto, M.: Pathobiology of hepatitis delta virus. J. Hepatol. 1993; 17(Suppl. 3) 149–153

    Google Scholar 

  31. Ottobrelli, A., Marzano, A., Smedile, A., Recchia, S., Salizzoni, M., Cornu, C., Lamy, M.E., Otte, J.B., De Hemptinne, B., Geubel, A., Grendele, M., Colledan, M., Galmarini, D., Marinucci, G., Di Giacomo, C., Agnes, S., Bonino, F., Rizzetto, M.: Patterns of hepatitis delta virus reinfection and diease in liver transplantation. Gastroenterology 1991; 101: 1649–1655

    PubMed  CAS  Google Scholar 

  32. Pastore, G., Monno, L., Santantonio, T., Angavano, G., Milella, M., Giannelli, A., Fiore, J.R.: Hepatitis B virus clearance from serum and liver after acute hepatitis delta superinfection in chronic HBsAg carriers. J. Med. Virol. 1990; 31: 284–290

    PubMed  CAS  Google Scholar 

  33. Polish, L.B., Gallagher, M., Fields, H.A., Hadler, St.C.: Delta hepatitis: molecular biology and clinical and epidemiological features. Clin. Microbiol. Rev. 1993; 6: 211–229

    PubMed  CAS  Google Scholar 

  34. Rizzetto, M.: Hepatitis delta: the virus and the disease. J. Hepatol. 1990; 11: 145–148

    Google Scholar 

  35. Rizzetto, M., Hadziyannis, S., Hansson, B.G., Toukan, A., Gust, I.: Hepatitis delta virus infection in the world: epidemiological patterns and clinical expression. Gastroenterol. Internat. 1992; 5: 18–32

    Google Scholar 

  36. Rosenblum, L., Darrow, W., Witte, J., Cohen, J., French, J., Gill, P.S., Potterat, J., Sikes, K., Reich, R., Hadler, S.: Sexual practices in the transmission of hepatitis B virus and prevalence of hepatitis Delta virus infection in female prostitutes in the United States. J. Amer. Med. Assoc. 1992; 267: 2477–2481

    CrossRef  CAS  Google Scholar 

  37. Rosina, F., Saracco, G., Rizzetto, M.: Risk of transfusion infection with the hepatitis Delta virus. A multicenter study. New Engl. J. Med. 1985; 312: 1488–1491

    PubMed  CAS  Google Scholar 

  38. Salassa, B., Daziano, E., Bonino, F., Lavarini, C., Smedile, A., Chiaberge, E., Rosina, F., Brunetto, M.R., Pessione, E., Spezia, C., Bramato, C., Soranzo, M.L.: Serological diagnosis of hepatitis B and delta virus (HBV/HDV) coinfection. J. Hepatol. 1991; 12: 10–13

    CrossRef  PubMed  CAS  Google Scholar 

  39. Stroffolini, T., Ferrigno, L., Cialdea, L., Catapano, R., Palumbo, F., Novaco, F., Moiraghi, A., Galanti, C., Bernacchia, R., Mele, A.: Incidence and risk factors of acute Delta hepatitis in Italy: results from a national surveillance system. J. Hepatol. 1994; 21: 1123–1126

    CrossRef  PubMed  CAS  Google Scholar 

  40. Tassopoulos, N.C., Koutelou, M.G., Macagno, S., Zorbas, P., Rizzetto, M.: Diagnostic significance of IgM antibody to hepatitis delta virus in fulminant hepatitis. J. Med. Virol. 1990; 30: 174–177

    PubMed  CAS  Google Scholar 

  41. Taylor, J.M.: Hepatitis delta virus. Intervirology 1999; 42: 173–178

    CrossRef  PubMed  CAS  Google Scholar 

  42. Tibbs, C.J.: Delta hepatitis in Kiribati: a pacific focus. J. Med. Virol. 1989; 29: 130–132

    PubMed  CAS  Google Scholar 

  43. Verme, G., Brunetto, M.R., Oliveri, F., Baldi, M., Forzani, B., Piantino, P., Ponzetto, A., Bonino, F.: Role of hepatitis delta virus infection in hepatocellular carcinoma. Dig. Dis. Sci. 1991; 36: 1134–1136

    CrossRef  PubMed  CAS  Google Scholar 

  44. Wang, T.C., Chao, M.: Molecular cloning and expression of the hepatitis delta virus genotype II b genome. Biochem. Biophys. Res. Comm. 2003; 303: 357–363

    PubMed  CAS  Google Scholar 

  45. Weisfuse, I.B., Hadler, S.C., Fields, H.A., Alter, M.J., O’Malley, P.M., Judson, F.N., Ostrow, D.G., Altmann, N.L.: Delta hepatitis in homosexual men in the United States. Hepatology 1989; 9: 872–874

    PubMed  CAS  Google Scholar 

  46. Wu, J.-C., Lee, S.-D., Govindarajan, S., Lin, H.-C., Chou, P., Wang, Y.-J., Lee, S.-Y., Tsai, Y.-T., Lo, K.-J., Ting, L.-P.: Sexual transmission of hepatitis D virus infection in Taiwan. Hepatology 1990; 11: 1057–1061

    PubMed  CAS  Google Scholar 

  47. Wu, J.-C., Chen, T.-Z., Huang, Y.-S., Yen, F.-S., Ting, L.-T., Sheng, W.-Y., Tsay, S.-H., Lee, S.-D.: Natural history of hepatitis D viral superinfection: significance of viremia detected by polymerase chain reaction. Gastroenterology 1995; 108: 796–802

    CrossRef  PubMed  CAS  Google Scholar 

Acute viral hepatitis E

  1. Aggarwal, R., Naik, S.R.: Hepatitis E: intrafamilial transmission versus waterborne spread. J. Hepatol. 1994; 21: 718–723

    PubMed  CAS  Google Scholar 

  2. Aggarwal, R., Krawczynski, K.: Hepatitis E: an overview and recent advances in clinical and laboratory research. J. Gastroenterol. Hepatol. 2000; 15: 9–20

    CrossRef  PubMed  CAS  Google Scholar 

  3. Al-Azmeh, J., Frösner, G., Darwish, Z., Bashour, H., Monem, F.: Hepatitis E in Damascus, Syria. Infection 1999; 27: 221–223

    PubMed  CAS  Google Scholar 

  4. Arankalle, V.A., Chadha, M.S., Mehendale, S.M., Banerjee, K: Outbreak of enterically transmitted non-A, non-B hepatitis among schoolchildren. Lancet 1988; II: 1199–1200

    Google Scholar 

  5. Arora, N.K., Panda, S.K., Nanda, S.K., Ansari, I.H., Joshi, S., Dixit, R., Bathia, R.: Hepatitis E infection in children: study of an outbreak. J. Gastroenterol. Hepatol. 1999; 14: 572–577

    CrossRef  PubMed  CAS  Google Scholar 

  6. Balayan, M.S.: Hepatitis E virus infection in Europe: regional situation regarding laboratory diagnosis and epidemiology. Clin. Diagn. Virol. 1993; 1: 1–9

    CrossRef  PubMed  CAS  Google Scholar 

  7. Bradley, D.W.: Hepatitis E virus: a brief review of the biology, molecular virology, and immunology of a novel virus. J. Hepatol. 1995; 22(Suppl. 1): 140–145

    PubMed  CAS  Google Scholar 

  8. Chauhan, A., Jameel, S., Dilawari, J.B., Chawla, Y.K., Kaur, U., Ganguly, N.K.: Hepatitis E virus transmission to a volunteer. Lancet 1993; 341: 149–150

    PubMed  CAS  Google Scholar 

  9. Chow, W.C., Lee, A.S:G., Lim, G.K., Cheong, W.K., Chong, R., Tan, C.K., Yap, C.K., Oon, C.J., Ng, H.S.: Acute viral hepatitis E: clinical and serologic studies in Singapore. J. Clin. Gastroenterol. 1997; 24: 235–238

    CrossRef  PubMed  CAS  Google Scholar 

  10. Clayson, E.T., Myint, K.S.A., Snitbhan, R., Vaughn, D.W., Innis, B.L., Chan. L., Cheung, P., Shrestha, M.P.: Viremia, fecal shedding, and IgM and IgG responses in patients with hepatitis E. J. Infect. Dis. 1995; 172: 927–933

    PubMed  CAS  Google Scholar 

  11. De Cock, K.M., Bradley, D.W., Sandford, N.G., Govindarajan, S., Maynard, J.E., Redeker, A.G.: Epidemic non-A, non-B hepatitis in patients from Pakistan. Ann. Intern. Med. 1987; 106: 227–230

    PubMed  Google Scholar 

  12. Derong, L., Rutong, H., Xing, T., Shurong, Y., Jun, W., Xiangrui, H., Baozhen, W., Ruixia, L., Yuchuan, L.: Morphology and morphogenesis of hepatitis E virus (strain 87 A). Chin. Med. J. 1995; 108: 126–131

    Google Scholar 

  13. El-Zimaity, D.M.T., Hyams, K.C., Imam, Z.E.T., Watts, D. M., Bassily, S., Naffea, E.K., Sultan, E., Emaru, K., Burans, J., Purdy, M.A., Bradley, D.W., Carl, M.: Acute sporadic hepatitis E in an Egyptian pediatric population. Amer. J. Trop. Med. Hyg. 1993; 48: 372–376

    CAS  Google Scholar 

  14. Favoro, M.O., Kosoy, M.Y., Tsarev, S.A., Childs, J.E., Margolis, H.S.: Prevalence of antibody to hepatitis E virus among rodents in the United States. J. Infect. Dis. 2000; 181: 449–455

    Google Scholar 

  15. Grabow, W.O.K., Favorov, M.O., Khudyakova, N.S., Taylor, M.B., Fields, H.A.: Hepatitis E seroprevalence in selected individuals in South Africa. J. Med. Virol. 1994; 44: 384–388

    PubMed  CAS  Google Scholar 

  16. Harrison, T.J.: Hepatitis E virus — an update. Liver 1999; 19: 171–176

    PubMed  CAS  Google Scholar 

  17. Hofmann, H., Holzmann, H.: Investigations regarding the occurrence of hepatitis E in Austria. Wien. Klin. Wschr. 1995; 107: 336–339

    PubMed  CAS  Google Scholar 

  18. Irshad, M.: Hepatitis E virus: an update on its molecular, clinical and epidemiological characteristics. Intervirology 1999; 42: 252–262

    CrossRef  PubMed  CAS  Google Scholar 

  19. Jardi, R., Buti, M., Rodriguez-Frias, F., Esteban, R.: Hepatitis E infection in acute sporadic hepatitis in Spain. Lancet 1993; 341: 1355–1356

    CrossRef  PubMed  CAS  Google Scholar 

  20. Kane, M.A., Bradley, D.W., Shrestha, S.M., Maynard, J.E., Cook, E.H., Mishra, R.P., Joshi, D.D.: Epidemic non-A, non-B hepatitis in Nepal. J. Amer. Med. Assoc. 1984; 22: 3140–3145

    Google Scholar 

  21. Karetnyi, Y.V., Favorov, M.O., Khudyakova, N.S., Weiss, P., Bar-Shani, S., Handsher, R., Aboudy, Y., Varsono., N., Schwartz, E., Levin, E., Mendelson, E., Fields, H.A.: Serological evidence for hepatitis E virus infection in Israel. J. Med. Virol. 1995; 45: 316–320

    PubMed  CAS  Google Scholar 

  22. Khuroo, M.S.: Study of an epidemic of non-A, non-B hepatitis. Possibility of another human hepatitis virus distinct from post-transfusion non-A, non-B type. Amer. J. Med. 1980; 68: 818–824

    PubMed  CAS  Google Scholar 

  23. Khuroo, M.S., Kamili, S.: Aetiology, clinical course and outcome of sporadic acute viral hepatitis E in pregnancy. J. Viral Hepat. 2003; 10: 61–69

    PubMed  CAS  Google Scholar 

  24. Lau, J.Y.N., Sallie, R., Fang, J.W.S., Yarbough, P.O., Reyes, G.R., Portmann, B.C., Mieli-Vergani, G., Williams, R.: Detection of hepatitis E virus genome and gene products in two patients with fulminant hepatitis E. J. Hepatol. 1995; 22: 605–610

    PubMed  CAS  Google Scholar 

  25. Lavanchy, D.: Seroprevalence of hepatitis E virus in Switzerland. Lancet 1994; 344: 747–748

    CrossRef  PubMed  CAS  Google Scholar 

  26. Lee, S.-D., Wang, Y.-J., Lu, R.-H., Chan, C.-Y., Lo, K.-J., Moeckli, R.: Seroprevalence of antibody to hepatitis E virus among Chinese subjects in Taiwan. Hepatology 1994: 19: 866–870

    CrossRef  PubMed  CAS  Google Scholar 

  27. Meng, X.J., Purcell, R.H., Halbur, P.G., Lehman, J.K., Webb, D.M., Tsareva, T.S., Haynes, J.S., Thacker, B.J., Emerson, S.U.: A novel virus in swine is closely related to the human hepatitis E virus. Proc. Natl. Acad. Sci. 1997; 94: 9860–9865

    PubMed  CAS  Google Scholar 

  28. Moaven. L., van Asten, M., Crofts, N., Locarnini, St.A.: Seroepidemiology of hepatitis E in selected Australian populations. J. Med. Virol. 1995; 45: 326–330

    PubMed  CAS  Google Scholar 

  29. Mushahwar, I.K., Dawson, G.J., Bile, K.M., Magnius, L.O.: Serological studies of an enterically transmitted non-A, non-B hepatitis in Somalia. J. Med. Virol. 1993; 40: 218–221

    PubMed  CAS  Google Scholar 

  30. Nanda, S.K., Yalcinkaya, K., Panigrahi, A.K., Acharya, S.K., Jameel, S., Panda, S.K.: Etiological role of hepatitis E virus in sporadic fulminant hepatitis. J. Med. Virol. 1994; 42: 133–137

    PubMed  CAS  Google Scholar 

  31. Nanda, S.K., Ansari, I.H., Acharya, S.K., Jameel, S., Panda, S.K.: Protracted viremia during acute sporadic hepatitis E virus infection. Gastroenterology 1995; 108: 225–230

    CrossRef  PubMed  CAS  Google Scholar 

  32. Pujol, F.H., Favorov, M.O., Marcano, T., Este, J.A., Magris, M., Liprandi, F., Khudyakov, Y.E., Khudyakov, N.S., Fields, H.A.: Prevalence of antibodies against hepatitis E virus among urban and rural populations in Venezuela. J. Med. Virol. 1994, 42: 234–236

    PubMed  CAS  Google Scholar 

  33. Ramalingaswami, V., Purcell, R.H.: Waterborne non-A, non-B hepatitis. Lancet 1988/II: 571–573

    Google Scholar 

  34. Ray, R., Aggarwal, R., Salunke, P.N., Mehrotra, N.N., Talwar, G.P., Naik, S.R.: Hepatitis E virus genome in stools of hepatitis patients during large epidemic in north India. Lancet 1991; 338: 783–784

    CrossRef  PubMed  CAS  Google Scholar 

  35. Reyes, G.R., Purdy, M.A., Kim, J.P., Luk, K.-C., Young, L.M., Fry, K.E., Bradley, D.W.: Isolation of a cDNA from the virus responsible for enterically transmitted non-A, non-B hepatitis. Science 1990; 247: 1335–1339

    PubMed  CAS  Google Scholar 

  36. Schlauder, G.G., Mushahwar, I.K.: Genetic heterogeneity of hepatitis E virus. J. Med. Virol. 2001; 65: 282–292

    CrossRef  PubMed  CAS  Google Scholar 

  37. Schwartz, E., Jenks, N.P., van Damme, P., Galun, E.: Hepatitis E virus infection in travellers. Clin. Inf. Dis. 1999; 29: 1312–1314

    CAS  Google Scholar 

  38. Skidmore, S.J., Yarbough, P.O., Gabor, K.A., Reyes, G.R.: Hepatitis E virus (HEV): the cause of a waterborne hepatitis outbreak. J. Med. Virol. 1992; 37: 58–60

    PubMed  CAS  Google Scholar 

  39. Suzuki, K., Aikawa, T., Okamoto, H.: Fulminant Hepatitis E in Japan. New Engl. J. Med. 2002; 347: 1456.

    CrossRef  PubMed  Google Scholar 

  40. Tandon, B.N., Joshi, Y.K., Jain, S.K., Gandhi, B.M., Mathiesen, L.R., Tandon, H.D.: An epidemic of non-A, non-B hepatitis in north India. Indian J. Med. Res. 1982; 75: 739–744

    Google Scholar 

  41. Tassopoulos, N.C., Krawczynski, K., Hatzakis, A., Katsoulidou, A., Delladepsima, I., Koutelou, M.G., Trichopoulos, D.: Role of hepatitis E virus in the etiology of community-acquired non-A, non-B hepatitis in Greece. J. Med. Virol. 1994; 42: 124–128

    PubMed  CAS  Google Scholar 

  42. Thomas, D.L., Mahley, R.W., Badur, S., Palaoglu, K.E., Quinn, T.C.: Epidemiology of hepatitis E virus infection in Turkey. Lancet 1993; 341: 1561–1562

    PubMed  CAS  Google Scholar 

  43. Ticehurst, J., Popkin, T.-J., Bryan, J.P., Innis, B.L., Duncan, J.F., Ahmed, A., Iübal, M., Malik, I., Kapikian, A.Z., Legters, L.J., Purcell, R.H.: Association of hepatitis E virus with an outbreak of hepatitis in Pakistan: serological responses and pattern of virus excretion. J. Med. Virol. 1992; 36: 84–92

    PubMed  CAS  Google Scholar 

  44. Tsega, E., Krawczynski, K., Hansson, B.G., Nordenfelt, E., Negusse, Y., Alemu, W., Bahru, Y.: Outbreak of acute hepatitis E virus infection among military personel in northern Ethiopia. J. Med. Virol. 1991; 34: 232–236

    PubMed  CAS  Google Scholar 

  45. Vandenvelde, C.: Hepatitis E virus infection in Belgian soldiers. Lancet 1994; 344: 747.

    PubMed  CAS  Google Scholar 

  46. Velazquez, O., Stetler, H.C., Avila, C., Ornelas, G., Alvarez, C., Hadler, St. C., Bradley, D.W., Sepulveda, J.: Epidemic transmission of enterically transmitted non-A, non-B hepatitis in Mexico, 1986–1987. J. Amer. Med. Assoc. 1990; 263: 3281–3285

    CrossRef  CAS  Google Scholar 

  47. Viswanathan, R.: Infectious hepatitis in Delhi (1955–56): a critical study: epidemiology. Indian J. Med. Res. 1957; 45(Suppl.): 1–30

    PubMed  CAS  Google Scholar 

  48. Wong, D.C., Purcell, R.H., Sreenivasan, M.A., Prasad, S.R., Pavri, K.M.: Epidemic and endemic hepatitis in India, evidence for a non-A, non-B hepatitis virus aetiology. Lancet 1980/II: 876–879

    Google Scholar 

  49. Yarbough, P.O.: Advances in hepatitis E. Curr. Opin. Infect. Dis. 1997; 10: 398–401

    Google Scholar 

  50. Zaaijer, H.L., Mauser-Bunschoten, E.P., ten Veen, J.H., Kapprell, H.P., Kok, M., von den Berg, H.M., Lelie, P.N.: Hepatitis E virus antibodies among patients with hemophilia, blood donors, and hepatitis patients. J. Med. Virol. 1995; 46: 244–246

    PubMed  CAS  Google Scholar 

  51. Zanetti, A.R., Dawson, G.J.: Hepatitis type E in Italy: seroepidemiological survey. J. Med. Virol. 1994; 42: 318–320

    PubMed  CAS  Google Scholar 

Acute viral hepatitis NA-NE

  1. Arankalle, V.A., Chadha, M.S., Tsarev. S.A., Emerson, S.U., Risbud, A.R., Banerjee, K., Purcell, R.H.: Seroepidemiology of water-borne hepatitis in India und evidence for a third enterically-transmitted hepatitis agent. Proc. Nat. Acad. Sci. (USA) 1994; 91: 3428–3432

    PubMed  CAS  Google Scholar 

  2. Chu, C.M., Lin, D.Y., Yeh, C.T., Sheen, I.S., Liaw, Y.F.: Epidemiological characteristics, risk factors, and clinical manifestations of acute non-A-E hepatitis. J. Med. Virol. 2001; 65: 296–300

    CrossRef  PubMed  CAS  Google Scholar 

  3. Rochling, F.A., Jones, W.F., Chau, K., DuCharme, L., Mimms, L.T., Moore, B., Scheffel, J., Cuthbert, J.A., Thiele, D.L.: Acute sporadic Non-A, Non-B, Non-C, Non-D, Non-E hepatitis. Hepatology 1997, 25: 478–483

    PubMed  CAS  Google Scholar 

F virus

  1. Deka, N., Sharma, M.D., Mukerjee, R.: Isolation of the novel agent from human stool samples that is associated with sporadic non-A, non-B hepatitis. J. Virol. 1994; 68: 7810–7815

    PubMed  CAS  Google Scholar 

HG virus

  1. Alter, M.J., Gallagher, M., Morris, T.T., Moyer, L.A., Meeks, E.L., Krawczynski, K., Kim, J.P., Margolis, H.S.: Acute non-A-E-hepatitis in the United States and the role of hepatitis G virus infection. New Engl. J. Med. 1997; 336: 741–746

    PubMed  CAS  Google Scholar 

  2. Berenguer, M., Terrault, N.A., Piatak, M., Yun, A., Kim, J.P., Lau, J.Y.N., Lake, J.R., Roberts, J.R., Ascher, N.L., Ferrell, L., Wright, T.L.: Hepatitits G virus infection in patients with hepatitis C virus infection undergoing liver transplantation. Gastroenterology 1996; 111: 1569–1575

    CrossRef  PubMed  CAS  Google Scholar 

  3. Berg, T., Schreier, E., Heuft, H.G., Naumann, U., Neuhaus, P., Huhn, D., Hopf, U.: Hepatitis-G-Virus-Infektion: epidemiologische Aspekte und klinische Relevanz. Dtsch. Med. Wschr. 1997; 122: 268–274

    PubMed  CAS  Google Scholar 

  4. Bortolotti, F., Tagger, A., Giacchino, R., Zuccotti, G.V., Crivellaro, C., Balli, F., Barbera, C., Vajro, P., Nebbia, G., Ribero, M.L.: Hepatitis G and C virus coinfection in children. J. Pediatr. 1997; 131: 639–640

    PubMed  CAS  Google Scholar 

  5. Colombatto, P., Randone, A., Civitico, G., Monti Gorin, J., Dolci, L., Medaina, N., Oliveri, F., Verme, G., Marchiaro, G., Pagni, R., Karayiannis, P., Thomas, H.C., Hess, G., Bonino, F., Brunetto, M.R.: Hepatitis G virus RNA in the serum of patients with elevated gamma glutamyl transpeptidase and alkaline phosphatase: a specific liver disease. J. Viral Hepat. 1996; 3: 301–306

    PubMed  CAS  Google Scholar 

  6. Feucht, H.H., Zollner, B., Polywka, S., Knodler, B., Schroter, M., Nolte, H., Laufs, R.: Prevalence of hepatitis G-viremia among healthy subjects, individuals with liver disease and persons at risk for parenteral transmission. J. Clin. Microbiol. 1997; 35: 767–768

    PubMed  CAS  Google Scholar 

  7. Frey, S.E., Homan, S.M., Sokol-Anderson, M., Cayco, M.T., Cortorreal, P., Musial, C.E., di Bisceglie, A.: Evidence for probable sexual transmission of the hepatitis G virus. Clin. Infect. Dis. 2002; 34: 1033–1038

    CrossRef  PubMed  Google Scholar 

  8. Hayashi, J., Furusyo, N., Sawayama, Y., Kishihara, Y., Kawakami, Y., Ariyama, I., Etoh, Y., Kashiwagi, S.: Hepatitis G virus in the general population and in patients as hemodialysis. Dig. Dis. Sci. 1998; 43: 2143–2148

    PubMed  CAS  Google Scholar 

  9. Hollingsworth, R.C., Minton, E.J., Fraser-Moodie, C., Metivier, E., Rizzi, P.M., Irving, W.L., Jenkins, D., Ryder, S.D.: Hepatitis G infection: role in cryptogenic chronic liver disease and primary liver cell cancer in the UK. J. Vir. Hepat. 1998; 5: 165–169

    CAS  Google Scholar 

  10. Ideura, T., Tanaka, E., Nakatsuji, Y., Kobayashi, M., Kanno, Y., Oguchi, H., Hora, K.: Clinical significance of hepatitis G virus infection in patients on long-term haemodialysis. J. Gastroenterol. Hepatol. 1997; 12: 762–765

    PubMed  CAS  Google Scholar 

  11. Jarvis, L.M., Davidson, F., Hanley, J.P., Yap, P.L., Ludlam, C.A., Simmonds, P.: Infection with hepatitis G virus among recipients of plasma products. Lancet 1996; 348: 1352–1355

    CrossRef  PubMed  CAS  Google Scholar 

  12. Karayiannis, R., Hadziyannis, S.J., Kim, J., Pickering, J.M., Piatak, M., Hess, G., Yun, A., McGarvey, M.J., Wages, J., Thomas, H.C.: Hepatitits G virus infection: clinical characteristics and response to interferon. J. Viral Hepat. 1997; 4: 37–44

    CrossRef  PubMed  CAS  Google Scholar 

  13. Kobayashi, M., Chayama, K., Fukuda, M., Tsubota, A., Suzuki, Y., Arase, Y., Koida, I., Saitoh, S., Murashima, N., Ikeda, K., Koike, H., Hashimoto, M., Miyano, Y., Kobayashi, M., Kumada, H.: Biochemical and histological features of hepatitis G virus infection. J. Gastroenterol. Hepatol. 1998; 13: 767–772

    PubMed  CAS  Google Scholar 

  14. Linnen, J., Wages, J. jr., Zhang-Keck, Z.-Y., Fry, K.E., Krawczynski, K.Z., Alter, H., Koonin, E., Gallagher, M., Alter, M., Hadziyannis, St., Karayiannis, P. et al.: Molecular cloning and disease association of hepatitis G virus: a transfusion-transmissible agent. Science 1996; 271: 505–508

    PubMed  CAS  Google Scholar 

  15. Moaven, L.D., Locarnini, S.A., Bowden, D.S., Kim, J.P., Breschkin, A., McCaw, R., Yun, A., Wages, J., Jones, B., Angus, P.: Hepatitis G virus and fulminant hepatic failure: evidence for transfusion-related infection. J. Hepatol. 1997; 27: 613–619

    CrossRef  PubMed  CAS  Google Scholar 

  16. Nakatsuji, Y., Wai-Kuo Shih, J., Tanaka, E., Kiyosawa, K., Wages, J. jr., Kim, J.P., Alter, H.J.: Prevalence and disease association of hepatitis G virus infection in Japan. J. Viral Hepat. 1996; 3: 307–316

    PubMed  CAS  Google Scholar 

  17. Petrik, J., Guella, L., Wight, D.G.D., Pearson, G.M., Hinton, J., Parker, H., Allain, J.-P., Alexander, G.J.M.: Hepatic histology in hepatitis C virus carriers coinfected with hepatitis G virus. Gut 1998; 42: 103–106

    PubMed  CAS  Google Scholar 

  18. Saito, T., Shiino, T., Arakawa, Y., Hayashi, S., Abe, K.: Geographical characterization of hepatitis G virus genome: evidence for HGV genotypes based on phylogenetic analysis. Hepatol. Res. 1998; 10: 121–130

    Google Scholar 

  19. Stark, K., Bienzle, U., Hess, G., Engel, A.M., Hegenscheid, B., Schlüter, V.: Detection of the hepatitis G virus genome among injection drug abusers, homosexual and bisexual men, and blood donors. J. Infect. Dis. 1996; 174: 1320–1323

    PubMed  CAS  Google Scholar 

  20. Thomas, D.L., Nakatsuji, Y., Shih, J.W., Alter, H.J., Nelson, K.E., Astemborski, J.A., Lyles, C.M., Vlahov, D.: Persistence and clinical significance of hepatitis G virus infection in injecting drug users. J. Infect. Dis. 1997; 176: 586–592

    PubMed  CAS  Google Scholar 

  21. Torres, C., de Rueda, P.M., Ruiz-Extremera, A., Quintero, D., Palacios, A., Salmeron, J.: Genomic and antigenomic chains of hepatitis C virus and hepatitis G virus in serum, liver and peripheral blood mononuclear cells. Rev. Esp. Enferm. Dig. 2002; 94: 664–668

    Google Scholar 

  22. Umlauft, F., Wong, D.T., Underhill, P.A., Oefner, P.J., Jin, L., Urbanek, M., Gruewald, K., Greenberg, H.B.: Hepatitis G virus infection in hemodialysis patients and the effects of interferon treatment. Amer. J. Gastroenterol. 1997; 92: 1986–1991

    CAS  Google Scholar 

  23. Woelfle, J., Berg, T., Keller, K.M., Schreier, E., Lentze, M.J.: Persistent hepatitis G virus infection after neonatal transfusion. J. Pediat. Gastroenterol. Nutrit. 1998; 26: 402–407

    CAS  Google Scholar 

GB viruses

  1. Cheng, P.N., Chang, T.T., Jen, C.M., Ko, A.W., Young, K.C., Wu, H.L.: Molecular evidence for transmission of GB virus-C/hepatitis G virus infection within family: close relationship between mother and child. Hepato-Gastroenterol. 2003; 50: 151–156

    CAS  Google Scholar 

  2. Christensen, P.B., Fisker, N., Mygind, L.H., Krarup, H.B., Wedderkopp, N., Varming, K., Georgsen, J.: GB virus C epidemiology in Denmark: Different routes of transmission in children and low-and high-risk adults. J. Med. Virol. 2003; 70: 156–162

    CrossRef  PubMed  Google Scholar 

  3. Deinhardt, F., Holmes, A.W., Capps, R.B., Popper, H: Studies on the transmission of human viral hepatitis to marmoset monkeys. Transmission of disease, serial passages, and description of liver lesions. J. Exper. Med. 1967; 125: 673–687

    CrossRef  CAS  Google Scholar 

  4. Heringlake, S., Ockenga, J., Tillman, H.L., Trautwein, C., Meissner, D., Stoll, M., Hunt, J., Jou, C., Solomon, N., Schmidt, R.E., Manns, M.P.: GB virus-C / hepatitis G virus infection: a favorable prognostic factor in human immunodeficiency virus-infected patients? J. Infect. Dis. 1998; 177: 1723–1726

    PubMed  CAS  Google Scholar 

  5. Kato, T., Mizokami, M., Nitta, M., Nakamura, M., Hiramatsu, H., Sugihara, K., Kato, A., Mukaide, M., Ueda, R.: Acute GB virus C / hepatitis G virus hepatitis preceding aplastic anemia. Hepatol. Res. 1997; 9: 164–171

    Google Scholar 

  6. Kiyosawa, K., Tanaka, E.: GB virus-C / hepatitis G virus. Intervirology 1999; 42: 185–195

    CrossRef  PubMed  CAS  Google Scholar 

  7. Leary, T.P., Muerhoff, A.S., Simons, J.N., Pilot-Matias, T.J., Erker, J.C., Chalmers, M.L., Schlauder, G.G., Dawson, G.J., Desai, S.M., Mushahwar, I.K.: Sequence and genomic organization of GBV-C: a novel member of the flaviviridae associated with human Non-A-E hepatitis. J. Med. Virol. 1996; 48: 60–67

    CrossRef  PubMed  CAS  Google Scholar 

  8. Meng, X.W., Komatsu, M., Ohshima, S., Nakane, K., Fujii, T., Goto, T., Yoneyama, K., Kuramitsu, T., Mukaide, M.: GB virus C infection: clinical significance. Can. J. Gastroenterol. 1999; 13: 814–818

    PubMed  CAS  Google Scholar 

  9. Müller, C.: Pathogenicity of GBV-C / HGV infection. J. Vir. Hepat. 1999; 6(Suppl. 1): 49–52

    Google Scholar 

  10. Okuda, K., Kanda, T., Yokosuka, O., Hayashi, H., Yokozeki, K., Ohtake, Y., Irie, Y.: GB-virus-C infection among chronic haemodialysis patients: clinical implications. J. Gastroenterol. Hepatol. 1997; 12: 766–770

    PubMed  CAS  Google Scholar 

  11. Pereira, L.M.M.B., Spinelli, V., Ximenes, R.A., Cavalcanti, M.S., Melo, R., Juca, N., Mizokami, M., McFarlane, I.G.: Chronic hepatitis C infection: influence of the viral load, genotypes, and GBV-C/HGV coinfection on the severity of the disease in a Brazilian population. J. Med. Virol. 2002; 67: 27–32

    CrossRef  PubMed  Google Scholar 

  12. Roy, K.M., Bagg, J., Kennedy, C., Cameron, S., Simmonds, P., Lycett, C., Hunter, I., Taylor, M.: Prevalence of GBV-C infection among dental personnel. J. Med. Virol. 2003; 70: 150–155

    CrossRef  PubMed  Google Scholar 

  13. Sarrazin, C., Roth, W.K., Zeuzem, S.: Heterosexual transmission of GB virus-C / hepatitis G virus infection. Eur. J. Gastroenterol. Hepatol. 1997; 9: 1117–1120 · GB virus C / hepatitis G virus: discovery, epidemiology, diagnosis and clinical significance. Z. Gastroenterol. 1998; 36: 997–1008

    PubMed  CAS  Google Scholar 

  14. Schlauder, G.G., Dawson, G.J., Simons, J.N., Pilot-Matias, T.J., Gutierrez, R.A., Heynene, C.A., Knigge, M.F., Kurpiewski, G.S., Buijk, S.L., Leary, T.P., Muerhoff, A.S., Desai, S.M., Mushahwar, I.K.: Molecular and serologic analysis in the transmission of the GB hepatitis agents. J. Med. Virol. 1995; 45: 81–90

    Google Scholar 

  15. Seemayer, C.A., Viazov, S., Philipp, T., Roggendorf, M.: Detection of GBV-C / HGV RNA in saliva and serum, but not in urine of infected patients. Infection 1998; 26: 39–41

    PubMed  CAS  Google Scholar 

  16. Simons, J.N., Pilot-Matias, T.J., Leary, T.P., Dawson, G.J., Desai, S.M., Schlauder, G.G., Muerhoff, A.S., Erker, J.C., Buijk, S.L., Chalmers, M.L., van Sant, C.L., Mushahwar, I.K.: Identification of two flavivirus-like genomes in the GB hepatitis agent. Proc. Nat. Acad. Sci. 1995; 92: 3401–3405

    PubMed  CAS  Google Scholar 

  17. Simons, J.N., Leary, T.P., Dawson, G.J., Pilot-Matias, T.J., Muerhoff, A.S., Schlauder, G.G., Desai, S.M., Mushawar, I.K.: Isolation of novel virus-like sequences associated with human hepatitis. Nature Med. 1995; 1: 564–569

    PubMed  CAS  Google Scholar 

  18. Takacs, M., Szomor, K.N., Szendroi, A., Dencs, A., Brojnas, J., Rusvai, E., Berencsi, G.: Prevalence of GB virus C/hepatitis G virus in Hungary. FEMS Imm. Med. Microbiol. 2002; 34: 283–287

    CAS  Google Scholar 

  19. Stapleton, J.T.: GB virus type C/hepatitis G virus. Semin. Liver Dis. 2003; 23: 137–148

    PubMed  CAS  Google Scholar 

  20. Tanaka, T., Takeuchi, T., Inoue, K., Tanaka, S., Kohara, M.: Acute hepatitis caused by sexual or household transmission of GBV-C. J. Hepatol. 1997; 27: 1110–1112

    PubMed  CAS  Google Scholar 

TT virus

  1. Abe, K., Inami, T., Asano, K., Miyoski, C., Masaki, N., Hayaski, S., Ishikawa, K., Tokebe, Y., Win, K.M., El-Zayadi, A.R., Han, K.H., Zhang, D.Y.: TT virus infection is wide spread in the general populations from different geographical regions. J. Clin. Microbiol. 1999; 37: 2703–2705

    PubMed  CAS  Google Scholar 

  2. Choi, M.S., Lee, J.H., Koh, K.C., Lee, J.H., Paik, S.W., Rhee, P.L., Rhee, J.C., Choi, K.W., Huh, W.S., Oh, H.Y.: TT virus infection in patients on maintenance hemodialysis in Korea. Hepato-Gastroenterol. 2003; 50: 170–173

    Google Scholar 

  3. Deng, X.W., Terunuma, H., Handema, R., Sakamoto, M., Kitamura, T., Ito, M., Akahane, Y.: Higher prevalence and viral load of TT virus in saliva than in the corresponding serum: Another possible transmission route and replication site of TT virus. J. Med. Virol. 2000; 62: 531–537

    CrossRef  PubMed  CAS  Google Scholar 

  4. Gad, A., Tanaka, E., Orii, K., Rokuhara, A., Nooman, Z., El-Hamid-Serwah, A., El-Sherif, A., El-Essawy, M., Yoshizawa, K., Kiyosawa, K.: Clinical significance of TT virus infection in maintenance hemodialysis patients of an endemic area for hepatitis C infection. Hepatol. Res. 2002; 22: 13–19

    PubMed  Google Scholar 

  5. Iwaki, Y., Aiba, N., Tran, H.T.T., Ding, X., Hayashi, S., Arakawa, Y., Sata, T., Abe, K.: Simian TT virus (S-TTV) infection in patients with liver diseases. Hepatol. Res. 2003; 25: 135–142

    PubMed  CAS  Google Scholar 

  6. Matsubara, H., Michitaka, K., Horiike, N., Kihana, T., Yano, M., Mori, T., Onji, M.: Existence of TT virus DNA and TTV-like mini virus DNA in infant cord blood: mother-to-neonatal transmission. Hepatol. Res. 2001; 21: 280–287

    PubMed  CAS  Google Scholar 

  7. Mushahwar, I.K., Erker, J.C., Muerhoff, A.S., Leary, T.P., Simons, J.N., Birkenmeyer, L.G., Chalmers, M.L., Pilot-Matias, T.J., Dexai, S.M.: Molecular and biophysical characterization of TT virus: evidence for a new virus family infecting humans. Proc. Nat. Acad. Sci. 1999; 96: 3177–3182

    PubMed  CAS  Google Scholar 

  8. Niel, C., de Oliveira, J.M., Ross, R.S., Gomes, S.A., Roggendorf, M., Viazow, S.: High prevalence of TT virus infection in Brazilian blood donors. J. Med. Virol. 1999; 57: 259–263

    CrossRef  PubMed  CAS  Google Scholar 

  9. Nishizawa, T., Okamoto, H., Konishi, K., Yoshizawa, H., Miyakawa, Y., Mayumi, M.: A novel DNA virus (TTV) associated with elevated transaminase levels in posttransfusion hepatitis of unknown etiology. Biochem. Biophys. Res. Comm. 1997; 241: 92–97

    CrossRef  PubMed  CAS  Google Scholar 

  10. Pollicino, T., Raffa, G., Squadrito, G., Constantino, L., Cacciola, I., Brancatelli, S., Alafaci, C., Florio, M.G., Raimondo, G.: TT virus has a ubiquitous diffusion in human body tissues: analyses of paired serum and tissue samples. J. Viral Hepat. 2003; 10: 95–102

    CrossRef  PubMed  CAS  Google Scholar 

  11. Schröter, M., Feucht, H.-H., Zöllner, B., Knödler, B., Schäfer, P., Fischer, L., Laufs, R.: Prevalence of TTV viremia among healthy subjects and individuals at risk for parenterally transmitted diseases in Germany. Hepatol. Res. 1999; 13: 205–211

    Google Scholar 

  12. Simmonds, P., Davidson, F., Lycett, C., Prescott, L.E., MacDonald, D.M., Ellender, J., Yap, P.L., Ludiam, C.A., Haydon, G.H., Gillon, J., Jarvis, L.M.: Detection of a novel DNA virus (TTV) in blood donors and blood products. Lancet 1998; 352: 191–195

    PubMed  CAS  Google Scholar 

  13. Suzuki, F., Chayama, K., Tsubota, A., Akuta, N., Someya, T., Kobayashi, M., Suzuki, Y., Saitoh, S., Arase, Y., Ikeda, K., Kumada, H.: Pathogenic significance and organic virus levels in patients infected with TT virus. Intervirology 2001; 44: 291–297

    CrossRef  PubMed  CAS  Google Scholar 

  14. Tajiri, H., Tanaka, T., Sawada, A., Etani, Y., Kozaiwa, K., Mushiake, S., Mishiro, S.: Three cases TT virus infection and idiopathic neonatal hepatitis. Intervirology 2001; 44: 364–369

    CrossRef  PubMed  CAS  Google Scholar 

  15. Takacs, M., Balong, K., Toth, G., Balogh, Z., Szomor, K.N., Brojnas, J., Rusvai, E., Minarovits, J., Berencsi, G.: TT virus in Hungary: sequence heterogeneity and mixed infections. FEMS Imm. Med. Microbiol. 2003; 35: 153–157

    CAS  Google Scholar 

  16. Tokita, H., Murai, S., Kamitsukawa, H., Yagura, M., Harada, H., Takahashi, M., Okamoto, H.: High TT virus load as an independence factor associated with the occurrence of hepatocellular carcinoma among patients with hepatitis C virus-related chronic liver disease. J. Med. Virol. 2002; 67: 501–509

    CrossRef  PubMed  Google Scholar 

SEN virus

  1. Kao, J.-H.H., Chen, W., Chen, P.-J., Lai, M.-Y., Chen, D.-S.: Prevalence and implication of a newly identified infectious agent (SEN virus) in Taiwan. J. Infect. Dis. 2002; 185: 389–392

    CrossRef  PubMed  Google Scholar 

  2. Pirovano, S., Bellinzoni, M., Ballerini, C., Cariani, E., Duse, M., Altertini, A., Imberti, L.: Transmission of SEN virus from mothers to their babies. J. Med. Virol. 2002; 66: 421–427

    CrossRef  PubMed  Google Scholar 

  3. Lin, J.G., Goto, T., Nakane, K., Miura, K., Mikami, K., Ohshima, S., Yoneyama, K., Watanabe, S.: Clinical significance of SEN-virus on interferon response in chronic hepatitis C patients. J. Gastroenterol. Hepatol. 2003; 18: 1144–1149

    CrossRef  PubMed  CAS  Google Scholar 

  4. Rigas, B., Hasan, I., Rehman, R., Donahue, P., Wittkowski, K.M., Lebovics, E.: Effect on treatment outcome of coinfection with SEN viruses in patients with hepatitis C. Lancet 2001; 358: 1961–1962

    CrossRef  PubMed  CAS  Google Scholar 

  5. Schröter, M., Laufs, R., Zöllner, B., Knödler, B., Schäfer, P., Sterneck, M., Fischer, L., Feucht, H.-H.: Prevalence of SENV-H viremia among healthy subjects and individuals at risk for parenterally transmitted diseases in Germany. J. Viral Hepat. 2002; 9: 455–459

    PubMed  Google Scholar 

  6. Shibata, M., Wang, R.Y.-H., Yoshiba, M., Shih, J.W.-K., Alter, H.J., Mitamura, K.: The presence of a newly identified infectious agent (SEN virus) in patients with liver diseases and in blood donors in Japan. J. Infect. Dis. 2001; 184: 400–404

    CrossRef  PubMed  CAS  Google Scholar 

  7. Tanaka, Y., Primi, D., Wang, R.Y.H., Umemura, T., Yeo, A.E.T., Mizokami, M., Alter, H.J., Shih, J.W.-K.: Genomic and molecular evolutinonary analysis of a newly identified infectious agent (SEN virus) and its relationship to the TT virus family. J. Infect. Dis. 2001; 183: 359–367

    CrossRef  PubMed  CAS  Google Scholar 

  8. Tangkijvanich, P., Theambooniers, A., Sriponthong, M., Kullavanijaya, P., Poovorawan, Y.: SEN virus infection and the risk of hepatocellular carcinoma: A case-control study. Amer. J. Gastroenterol. 2003; 98: 2500–2504

    Google Scholar 

  9. Umemura, T., Yeo, A.E., Sottini, A., Moratto, D., Tanaka, Y., Wang, R.Y.-H., Shih, J.W.-K., Donahue, P., Primi, D., Alter, H.J.: SEN virus infection and its relationship to transfusion-associated hepatitis. Hepatology 2001; 33: 1303–1311

    CrossRef  PubMed  CAS  Google Scholar 

  10. Umemura, T., Tanaka, E., Ostapowicz, G., Brown, K.E., Heringlake, S., Tassopoulos, N.C., Wang, R.Y.H., Yeo, A.E.T., Shih, J.W.K., Manns, M.P., Lee, W.M., Kiyosawa, K., Alter, H.J.: Investigation of SEN virus infection in patients with cryptogenic acute liver failure, hepatitis-associated aplastic anemia, or acute and chronic non-A-E hepatitis. J. Infect. Dis. 2003; 188: 1545–1552

    CrossRef  PubMed  Google Scholar 

  11. Yoshida, H., Kato, N., Shiratori, Y., Shao, R.X., Wang, Y., Shiina, S., Omata, M.: Weak association between SEN virus viremia and liver disease. J. Clin. Microbiol. 2002; 40: 3140–3145

    PubMed  CAS  Google Scholar 

YF virus

  1. Takacs, M., Berencsi, G., Mezey, I., Brojnas, J., Barcsay, E., Garamvölgyi, E., Hütter, E., Ferenczi, E., Pipirasz, E., Hollos, I., Dömök, I.: Detection of transfusion-associated hepatitis caused by non-A, non-B, non-C flavivirus. Acta Microbiol. Immunol. Hungar. 1994; 41: 83–89

    CAS  Google Scholar 

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(2006). Acute viral hepatitis. In: Hepatology Principles and Practice. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-28977-1_22

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