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Hepatology Principles and Practice pp 323–331Cite as

Hepatorenal syndrome

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Keywords

  • Hepatic Encephalopathy
  • Acute Tubular Necrosis
  • Atrial Natriuretic Factor
  • Acute Viral Hepatitis
  • Hepatorenal Syndrome

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Alarabi, A.A., Danielson, B.G., Wikström, B., Kreuger, A., Tufveson, G.: Artificial renal and liver support in a severe hepatorenal syndrome of childhood. Acta Paediatr. 1992; 81: 75–78

    CAS  PubMed  Google Scholar 

  2. Alessandra, C., Debernardi-Venon, W., Marzano, A., Barletti, C., Fadda, M., Rizzetto, M.: Renal failure in cirrhotic patients: role of terlipressin in clinical approach to hepatorenal syndrome type 2. Eur. J. Gastroenterol. Hepatol. 2002; 14: 1363–1368

    Google Scholar 

  3. Angeli, P., Volpin, R., Gerunda, G., Craighero, R., Roner, P., Merenda, R., Amodio, P., Sticca, A., Caregaro, L., Maffei-Faccioli, A., Gatta, A.: Reversal of type I hepatorenal syndrome with the administration of midodrine and octreotide. Hepatology 1999; 29: 1690–1697

    CrossRef  CAS  PubMed  Google Scholar 

  4. Arroyo, V., Gines, P., Gerbes, A.L., Dudley, F.J., Gentilini, P., Laffi, G., Reynolds, T.B., Ring-Larsen, H., Schölmerich, J.: Definition and diagnostic criteria of refractory ascites and hepatorenal syndrome in cirrhosis. Hepatology 1996; 23: 164–176

    CAS  PubMed  Google Scholar 

  5. Badalamenti, S., Graziani, G., Salerno, F., Ponticelli, C.: Hepatorenal syndrome. New perspectives in pathogenesis and treatment. Arch. Intern. Med. 1993; 153: 1957–1967

    CrossRef  CAS  PubMed  Google Scholar 

  6. Bataller, R., Gines, P., Arroyo, V., Rodes, J.: Hepatorenal syndrome. Clin. Liver Dis. 2000; 4: 487–507

    CrossRef  CAS  PubMed  Google Scholar 

  7. Biecker, E., Brensing, K.-A., Perz, J., Woitas, R., Sauerbruch, T.: Therapie des hepatorenalen Syndroms bei Leberzirrhose. Dtsch. Med. Wschr. 1999; 124: 1039–1042

    CAS  PubMed  Google Scholar 

  8. Brensing, K.-A., Textor, J., Perz, J., Schiedermaier, P., Raab, P., Strunk, H., Klehr, H.U., Kramer, H.J., Spengler, U., Schild, H., Sauerbruch, T.: Long-term otcome after transjugular intrahepatic portosystemic stentshunt in non-transplant cirrhotics with hepatorenal syndrome: a phase II study. Gut 2000; 47: 288–295

    CrossRef  CAS  PubMed  Google Scholar 

  9. Cacciafesta, M., Bonavita, M.S., Ferri, C., Piccirillo, G., Ettorre, E., Marigliano, V., Santucci, A., Balsano, F.: A new therapeutic approach to hepatorenal syndrome. Curr. Therap. Res. 1991; 50: 888–895

    Google Scholar 

  10. Chutaputti, A.: Management of refractory ascites and hepatorenal syndrome (review). J. Gastroenterol. Hepatol. 2002; 17: 456–461

    CrossRef  PubMed  Google Scholar 

  11. Colle, I., Durand, F., Pessione, F., Rassiat, E., Bernuau, E., Barriere, E., Lebrec, D., Valla, D.C., Moreau, R.: Clinical course, predictive factors and prognosis in patients with cirrhosis and type 1 hepatorenal syndrome treated with terlipressin: a retrospective analysis. J. Gastroenterol. Hepatol. 2002; 17: 882–888

    PubMed  Google Scholar 

  12. Dagher, L., Patch, D., Marley, R., Moore, K., Burroughs, A.: Review article: pharmacological syndrome with orthotopic liver transplantation. Acta Gastro-Enterol. Belg. 1992; 55: 350–357

    Google Scholar 

  13. Detroz, B., Honore, P., Monami, B., Meurisse, M., Canivet, J.L., Legrand, M., Damas, P., Jacquet, N.: Combined treatment of liver failure and hepatorenal snydrome with orthotopic liver transplantation. Acta Gastro-Enterol. Belg. 1992; 55: 350–357

    CAS  Google Scholar 

  14. Dudley, F.J., Kanel, G.C., Wood, L.J., Reynolds, T.B.: Hepatorenal syndrome without avid sodium retention. Hepatology 1986; 6: 248–251

    CAS  PubMed  Google Scholar 

  15. Duvoux, C., Zanditenas, D., Hezode, C., Chauvat, A., Monin, J.L., Roudot-Thoraval, F., Mallat, A., Dhumeaux, D.: Effects of noradrenalin and albumin in patients with type 1 hepatorenal syndrome: a pilot study. Hepatology 2002; 36: 374–380

    CrossRef  CAS  PubMed  Google Scholar 

  16. Epstein, M.: Peritoneovenous shunt in the management of ascites and the hepatorenal syndrome. Gastroenterology 1982; 82: 790–799

    CAS  PubMed  Google Scholar 

  17. Fevery, J., van Cutsem, E., Nevens, F., van Steenbergen, W., Verberckmoes, R., de Groote, J.: Reversal of hepatorenal syndrome in four patients by peroral misoprostol (prostaglandin E1 analogue) and albumin administration. J. Hepatol. 1990; 11: 153–158

    CrossRef  CAS  PubMed  Google Scholar 

  18. Fullen, W.D.: Hepatorenal syndrome: reversal by peritoneovenous shunt. Surgery 1977; 82: 337–341

    CAS  PubMed  Google Scholar 

  19. Gentilini, P., Vizzutti, F., Gentilini, A., Zipoli, M., Foschi, M., Romanelli, R.G.: Update on ascites and hepatorenal syndrome. Dig. Liver Dis. 2002; 34: 592–605

    CrossRef  CAS  PubMed  Google Scholar 

  20. Gines, A., Escorsell, A., Gines, P., Salo, J., Jimenez, W., Inglada, L., Navasa, M., Claria, J., Rimola, A., Arroyo, V., Rodes, J.: Incidence, predictive factors, and prognosis of the hepatorenal syndrome in cirrhosis with ascites. Gastroenterology 1993; 105: 229–236

    CAS  PubMed  Google Scholar 

  21. Gines, A., Salmeron, J.M., Gines, P., Arroyo, V., Jimenez, W., Rivera, F., Rodes, J.: Oral misoprostol or intravenous prostaglandin E2 do not improve renal function in patients with cirrhosis and ascites with hyponatremia or renal failure. J. Hepatol. 1993; 17: 220–226

    CrossRef  CAS  PubMed  Google Scholar 

  22. Gonwa, T.A., Morris, C.A., Goldstein, R.M., Husberg, B.S., Klintmalm, G.B.: Long-term survival and renal function following liver transplantation in patients with and without hepatorenal syndrome — experience in 300 patients. Transplantation 1991; 51: 428–430

    CAS  PubMed  Google Scholar 

  23. Gülberg, V., Bilzer, M., Gerbes, A.L.: Long-term therapy and retreatment of hepatorenal syndrome type I with ornipressin and dopamine. Hepatology 1999; 30: 870–875

    PubMed  Google Scholar 

  24. Guevara, M., Gines, P., Fernandez-Esparrach, G., Sort, P., Salmeron, J.M., Jimenez, W., Arroyo, V., Rodes, J.: Reversibility of hepatorenal syndrome by prolonged administration of ornipressin and plasma volume expansion. Hepatology 1998; 27: 35–41

    CrossRef  CAS  PubMed  Google Scholar 

  25. Gupta, S., Morgan, T.R., Gordan, G.S.: Calcitonin generelated peptide in hepatorenal syndrome. A possible mediator of peripheral vasodilation? J. Clin. Gastroenterol. 1992; 14: 122–126

    CAS  PubMed  Google Scholar 

  26. Hadengue, A., Gadano, A., Moreau, R., Giostra, E., Durand, F., Valla, D., Erlinger, S., Lebrec, D.: Beneficial effects of the 2-day administration of terlipressin in patients with cirrhosis and hepatorenal syndrome. J. Hepatol. 1998; 29: 565–570

    CrossRef  CAS  PubMed  Google Scholar 

  27. Helwig, F.C., Schutz, C.B.: A liver kidney syndrome. Clinical, pathological and experimental studies. Surg. Gynecol. Obstetr. 1932; 55: 570–580

    Google Scholar 

  28. Henriksen, J.H., Ring-Larsen, H.: Hepatorenal disorders: role of the sympathetic nervous system. Semin. Liver Dis. 1994; 14: 35–43

    CAS  PubMed  Google Scholar 

  29. Holt, S., Goodier, D., Marley, R., Patch, D., Burroughs, A., Fernando, B., Harry, D., Moore, K.: Improvement in renal function in hepatorenal syndrome with N-acetylcysteine. Lancet 1999; 353: 294–295

    CAS  PubMed  Google Scholar 

  30. Iwatsuki, S., Popovtzer, M.M., Corman, J.L., Ishikawa, M., Putnam, C.W., Katz, F.H., Starzl, T.E.: Recovery from “hepatorenal syndrome” after orthotopic liver transplantation. New Engl. J. Med. 1973; 289: 1155–1159

    CAS  PubMed  Google Scholar 

  31. Kearns, P.J., Polhemus, R.J., Oakes, D., Rabkin, R.: Hepatorenal syndrome managed with hemodialysis, then reversed by peritoneovenous shunting. J. Clin. Gastroenterol. 1985; 7: 341–343

    CAS  PubMed  Google Scholar 

  32. Kreuzer, W.: 12 Jahre Erfahrung mit dem kontinuierlichen, peritoneovenösen Shunt in der Behandlung des therapieresistenten Aszites und des hepatorenalen Versagens — Nutzen und Gefahren. Wien. Klin. Wschr. 1989; 101: 87–91

    CAS  PubMed  Google Scholar 

  33. Lang, F., Gerok, W., Häussinger, D.: New clues to the pathophysiology of hepatorenal failure. Clin. Invest. 1993; 71: 93–97

    CrossRef  CAS  Google Scholar 

  34. Lazinik, H.: Das hepatorenale Syndrom bei Virushepatitis. Med. Welt 1980; 31: 1596–1598

    CAS  PubMed  Google Scholar 

  35. Le Moine, O.: Hepatorenal syndrome-outcome after liver transplantation. Nephrol. Dialys. Transplant. 1998; 13: 20–22

    Google Scholar 

  36. Lenz, K., Hörtnagl, H., Druml, W., Reither, H., Schmid, R., Schneeweiss, B., Laggner, A., Grimm, G., Gerbes, A.L.: Ornipressin in the treatment of functional renal failure in decompensated liver cirrhosis. Effects on renal hemodynamics and atrial natriuretic factor. Gastroenterology 1991; 101: 1060–1067

    CAS  PubMed  Google Scholar 

  37. Lerut, J.P., Reynaert, M., de Plaen, J.F., Otte, J.B., Kestens, P.J.: Drainage péritonéo-veineux et syndrome hépato-rénal. Acta Gastro-Enterol. Belg. 1982; 45: 189–198

    CAS  Google Scholar 

  38. Linas, S.L., Schaefer, J.W., Moore, E.E., Good, J.T., Giansiracusa, R.: Peritoneovenous shunt in the management of the hepatorenal syndrome. Kidney Int. 1986; 30: 736–740

    CAS  PubMed  Google Scholar 

  39. Mas, A., Arroyo, V., Rodes, J., Bosch, J.: Ascites and renal failure in primary liver cell carcinoma. Brit. Med. J. 1975; 3: 629

    CAS  PubMed  Google Scholar 

  40. Mitzner, St.R., Stange, R., Klammt, S., Risler, T., Erley, C.M., Bader, B.D., Berger, E.D., Lauchart, W., Peszynski, P., Freytag, J., Hickstein, H., Loock, J., Löhr, J.-M., Liebe, St., Emmerich, J., Korten, G., Schmidt, R.: Improvement of hepatorenal syndrome with extracorporeal albumin dialysis MARS: results of a prospective, randomized, controlled clinical trial. Liver Transplant. 2000; 6: 277–286

    CrossRef  CAS  Google Scholar 

  41. Moore, K., Wendon, J., Frazer, M., Karani, J., Williams, R., Badr, K.: Plasma endothelin immunoreactivity in liver disease and the hepatorenal syndrome. New Engl. J. Med. 1992; 327: 1774–1778

    CAS  PubMed  Google Scholar 

  42. Moore, K.P., Taylor, G.W., Maltby, N.H., Siegers, D., Fuller, R.W., Dollery, C.T., Williams, R.: Increased production of cysteinyl leukotrienes in hepatorenal syndrome. J. Hepatol. 1990; 11: 263–271

    CrossRef  CAS  PubMed  Google Scholar 

  43. Moreau, R.: Hepatorenal syndrome in patients with cirrhosis. J. Gastroenterol. Hepatol. 2002; 17: 739–747

    CrossRef  CAS  PubMed  Google Scholar 

  44. Nonnenbruch, W.: Das hepatorenale Syndrom. Verh. Dtsch. Ges. Inn. Med. 1939; 51: 341–358

    Google Scholar 

  45. Phillips, A.O., Thomas, D.M., Coles, G.A.: Acute renal failure associated with non-fulminant hepatitis A. Clin. Nephrol. 1993; 39: 156–157

    CAS  PubMed  Google Scholar 

  46. Pladson, T.R., Parrish, R.M.: Hepatorenal syndrome: recovery after peritoneovenous shunt. Arch. Intern. Med. 1977; 137: 1248–1249

    CrossRef  CAS  PubMed  Google Scholar 

  47. Platt, J.F., Ellis, J.H., Rubin, J.M., Merion, R.M., Lucey, M.R.: Renal duplex Doppler ultrasonography: a noninvasive predictor of kidney dysfunction and hepatorenal failure in liver disease. Hepatology 1994; 20:362–369

    CrossRef  CAS  PubMed  Google Scholar 

  48. Poulos, A.M., Howard, L., Eisele, G., Rodgers, J.B.: Peritoneal dialysis therapy for patients with liver and renal failure with ascites. Amer. J. Gastroenterol. 1993; 88: 109–112

    CAS  Google Scholar 

  49. Richardière: Sur un cas d’ictère grave à forme rènale. Sem. Méd. 1890;10: 401–402

    Google Scholar 

  50. Rimola, A., Gavaler, J.S., Schade, R.R., El-Lankany, S., Starzl, E., van Thiel, D.H.: Effects of renal impairment on liver transplantation. Gastroenterology 1987; 93: 148–156

    CAS  PubMed  Google Scholar 

  51. Rosansky, S.J., Mullens, C.C.: The hepatorenal syndrome associated with metastatic angiosarcoma of the gallbladder. Ann. Intern. Med. 1982; 96: 191–192

    CAS  PubMed  Google Scholar 

  52. Schelling, J.R., Linas, St.L.: Hepatorenal syndrome. Semin. Nephrol. 1990; 10: 565–570

    CAS  PubMed  Google Scholar 

  53. Shear, L., Kleinerman, J., Gabuzda, G.J.: Renal failure in patients with cirrhosis of the liver. I. Clinical and pathological characteristics. Amer. J. Med. 1965; 39: 184–198

    CAS  PubMed  Google Scholar 

  54. Schmidt, P.: Nierenbeteiligung bei Lebererkrankungen. Pathophysiologie und Klinik. Klin. Wschr. 1983; 61: 1039–1047

    CAS  Google Scholar 

  55. Schroeder, E.T., Anderson, G.H. jr., Smulyan, H.: Effects of a portocaval or peritoneovenous shunt on renin in the hepatorenal syndrome. Kidney Int. 1979; 15: 54–61

    CAS  PubMed  Google Scholar 

  56. Schroeder, E.T., Numann, P.J., Chamberlain, B.E.: Functional renal failure in cirrhosis. Recovery after portocaval shunt. Ann. Intern. Med. 1970; 72: 923–928

    CAS  PubMed  Google Scholar 

  57. Solanki, P., Chawla, A., Garg, R., Gupta, R., Jaim, M., Sarin, S.K.: Beneficial effects of terlipressin in hepatorenal syndrome: A prospective randomized placebo-controlled clinical trial. J. Gastroenterol. Hepatol. 2003; 18: 152–156

    CrossRef  CAS  PubMed  Google Scholar 

  58. Solis-Herruzo, J.A., Duran, A., Favela, V., Castellano, G., Madrid, J.L., Munoz-Yague, M.T., Morillas, J.D., Estenoz, J.: Effects of lumbar sympathetic bloc on kidney function in cirrhotic patients with hepatorenal syndrome. J. Hepatol. 1987; 5: 167–173

    CAS  PubMed  Google Scholar 

  59. Uriz, J., Gines, P., Cardenas, A., Sort, P., Jimenez, W., Salmeron, J.M., Bataller, R., Mas, A., Navasa, M., Arroyo, V., Rodes, J.: Terlipressin plus albumin infusion: an effective and safe therapy of hepatorenal syndrome. J. Hepatol. 2000; 33: 43–48

    CrossRef  CAS  PubMed  Google Scholar 

  60. Watt, K., Uhanova, J., Minuk, G.Y.: Hepatorenal syndrome: diagnostic accuracy, clinical features, and outcome in a tertiary care center. Amer. J. Gastroenterol. 2002; 97: 2046–2050

    Google Scholar 

  61. Weiser, J.R., Pollok, M., Schoeppe, W., Hottenrott, C.: Peritoneovenöser Shunt bei terminaler dialysepflichtiger Niereninsuffizienz. Internist. Praxis 1985; 25: 477–481

    Google Scholar 

  62. Wong, P.Y., Talamo, R.C., Williams, G.H.: Kallikrein-kinin and reninangiotensin systems in functional renal failure of cirrhosis of the liver. Gastroenterology 1977; 73: 1114–1118

    CAS  PubMed  Google Scholar 

  63. Wong, F., Blendis, L.: New challenge of hepatorenal syndrome: prevention and treatment. Hepatology 2001; 34: 1242–1251

    CrossRef  CAS  PubMed  Google Scholar 

  64. Ziegenhagen, D.J., Look, K., Pohl, C., Pollok, M., Baldamus, C.A., Kruis, W.: Hepatorenales Syndrom: eine Indikation zum peritoneovenösen Shunt? Med. Welt 1991; 42: 674–677

    Google Scholar 

  65. Zipser, R.D., Radvan, G.H., Kronborg, I.J., Duke, R., Little, T.E.: Urinary thromboxane B2 and prostaglandin E2 in the hepatorenal syndrome: evidence for increased vasoconstrictor and decreased vasodilator factors. Gastroenterology 1983; 84: 697–703

    CAS  PubMed  Google Scholar 

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(2006). Hepatorenal syndrome. In: Hepatology Principles and Practice. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-28977-1_17

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