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Jaundice

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Keywords

  • Obstructive Jaundice
  • Acute Viral Hepatitis
  • Neonatal Jaundice
  • Unconjugated Bilirubin
  • Icteric Episode

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

Jaundice

  1. Baker, A.L., Rosenberg, I.H.: Hepatic complications of total parenteral nutrition. Amer. J. Med. 1987; 84: 489–492

    Google Scholar 

  2. Becker, S.D., Lamont, J.T.: Postoperative jaundice. Semin. Liver Dis. 1988; 8: 183–186

    CAS  PubMed  Google Scholar 

  3. Bird, A.R., Knottenbelt, E., Jacobs, P., Maigrot, J.: Primary shunt hyperbilirubinemia: a variant of the congenital dyserythropoietic anaemias. Postgrad. Med. J. 1991; 67: 396–398

    CAS  PubMed  Google Scholar 

  4. Fleming, C.R.: Hepatobiliary complications in adults receiving nutrition support. Dig. Dis. 1994; 12: 191–198

    CAS  PubMed  Google Scholar 

  5. Fulop, M., Katz, S., Lawrence, Ch.: Extreme hyperbilirubinemia. Arch. Intern. Med. 1971; 127: 254–258

    CrossRef  CAS  PubMed  Google Scholar 

  6. Greve, J.W.M., Gouma, D.J., Buurman, W.A.: Complications in obstructive jaundice: role of endotoxins. Scand. J. Gastroenterol. 1992; 27:(Suppl. 194): 8–12

    Google Scholar 

  7. Helftenbein, A., Windolf, J., Sänger, P., Hanisch, E.: Incidence and prognosis of postoperative icterus in intensive care surgical patients. Chirurg 1997; 68: 1292–1296

    CrossRef  CAS  PubMed  Google Scholar 

  8. Iishizaki, Y., Wakayama, T., Okada, Y., Kobayashi, T.: Magnetic resonance cholangiography for evaluation of obstructive jaundice. Amer. J. Gastroenterol. 1993; 88: 2072–2077

    Google Scholar 

  9. Kauffmann, G.W., Brambs, H.-J.: Verschlussikterus. Bildgebende Verfahren und interventionelle Radiologie. Dtsch. Ärztebl. 1988; 85: 2250–2255

    Google Scholar 

  10. Klaus, D., Feine, U.: Primäre Shunt-Hyperbilirubinämie. Dtsch. Med. Wschr. 1964; 89: 1973–1978

    CAS  PubMed  Google Scholar 

  11. Kuntz, H.-D., May, B.: Veränderungen der Leberfunktion bei Schockleber und akuter Stauungsleber. Intensivmedizin 1983; 20: 17–20

    Google Scholar 

  12. Matzen, P., Malchow-Moller, A., Hilden, J., Thomsen, C., Svendsen, L.B., Gammelgaard, E., Juhl, E.: Differential diagnosis of jaundice: a pocket diagnostic chart. Liver 1984; 4: 360–371

    CAS  PubMed  Google Scholar 

  13. McDonagh, A.F., Lightner, D.A.: Phototherapy and the photobiology of bilirubin. Semin. Liver Dis. 1988; 8: 272–283

    CAS  PubMed  Google Scholar 

  14. Miller, D.J., Keeton, G.R., Webber, B.L., Saunders, S.J.: Jaundice in severe bacterial infection. Gastroenterology 1976; 71: 94–97

    CAS  PubMed  Google Scholar 

  15. Molina, E.G., Reddy, K.R.: Postoperative jaundice. Clin. Liver Dis. 1999; 3: 477–488

    CrossRef  CAS  PubMed  Google Scholar 

  16. O’Connor, K.W., Snodgrass, P.J., Swonder, J.F., Mahoney, St., Burt, R., Cockerill, E.M., Lumeng, I.: A blinded prospective study comparing four current noninvasive approaches in the differential diagnosis of medical versus surgical jaundice. Gastroenterology 1983; 84: 1498–1504

    CAS  PubMed  Google Scholar 

  17. Pierach, C.A.: Gelbsucht bei Herzversagen. Icterus cardialis. Dtsch. Med. Wschr. 1974; 99: 1078–1084

    CAS  PubMed  Google Scholar 

  18. Quale, J.M., Mandel, L.J., Bergasa, N.V., Straus, E.W.: Clinical significance and pathogenesis of hyperbilirubinemia associated with Staphylococcus aureus septicemia. Amer. J. Med. 1988; 85: 615–618

    CAS  PubMed  Google Scholar 

  19. Rösch, W.: Endoskopische Verfahren zur Therapie des Verschlussikterus. Dtsch. Ärztebl. 1988; 85: 2246–2249

    Google Scholar 

  20. Scharschmidt, B.F., Goldberg, H.I., Schmid, R.: Approach to the patient with cholestatic jaundice. New Engl. J. Med. 1983; 308: 1515–1519

    CAS  PubMed  Google Scholar 

  21. Schölmerich, J., Spamer, C., Brambs, H.J.: Differentialdiagnose des Ikterus. Intern. Welt 1986; 7: 1–11

    Google Scholar 

  22. Vennes, J.A., Bond, J.H.: Approach to the jaundiced patient. Gastroenterology 1983; 84: 1615–1618

    CAS  PubMed  Google Scholar 

  23. Zimmermann, H.J., Fang, M., Utili, R., Seff, L.B., Hoofnagle, J.: Jaundice due to bacterial infection. Gastroenterology 1979; 77: 362–374

    Google Scholar 

Functional hyperbilirubinaemia

  1. Adams, J.A., Hey, D.J., Hall, R.T.: Incidence of hyperbilirubinemia in breast—s. formula-fed infants. Clin. Pediatr. 1985; 24: 69–73

    CAS  Google Scholar 

  2. Amit, Y., Poznansky, M.J., Schiff, D.: Neonatal jaundice and bilirubin encephalopathy: a clinical and experimental reappraisal. Isr. J. Med. Sci. 1992; 28: 103–108

    CAS  PubMed  Google Scholar 

  3. Arias, M.: Chronic unconjugated hyperbilirubinemia without overt signs of hemolysis in adolescents and adults. J. Clin. Invest. 1962; 41: 2233–2245

    CAS  PubMed  Google Scholar 

  4. Burchell, B., Hume, R.: Molecular genetic basis of Gilbert’s syndrome. J. Gastroenterol. Hepatol. 1999; 14: 960–966

    CrossRef  CAS  PubMed  Google Scholar 

  5. Caglayan, S., Candemir, H., Aksit, S., Kansov, S., Asik, S., Yapiak, I.: Superiority of oral agar and phototherapy combination in the treatment of neonatal hyperbilirubinemia. Pediatrics 1993; 92: 86–89

    CAS  PubMed  Google Scholar 

  6. Carre, D., Civadier, C., Foll, Y., Talarmin, B., Abgrall, J.: Le syndrome de Rotor. A propos d’un cas. Ann. Gastroenterol. Hepatol. 1994; 30: 255–259

    CAS  Google Scholar 

  7. Cosme, A., Martinez, S., Yuste, R., Alzate, L., Arenas, J.I., Gastaminza, A.: Sindrome de Dubin-Johnson. Presentacion de tres casos. Revision de la literature nacional. Rev. Esp. Enf. Digest. 1992; 82: 125–128

    CAS  Google Scholar 

  8. Crigler, J.F. jr., Najjar, V.A.: Congenital familial nonhemolytic jaundice with kernicterus. Pediatrics 1952; 10: 169–180

    PubMed  Google Scholar 

  9. De Morais, S.M.F., Uetrecht, J.P., Wells, P.G.: Decreased glucuronidation and increased bioactivation of acetaminophen in Gilbert’s syndrome. Gastroenterology 1992; 102: 577–586

    PubMed  Google Scholar 

  10. Dubin, I.N., Johnson, F.B.: Chronic idiopathic jaundice with unidentified pigment in liver cells: a new clinicopathologic entity with a report of 12 cases. Medicine 1954; 33: 155–197

    CAS  PubMed  Google Scholar 

  11. Frank, M., Doss, M., de Carvalho, D.G.: Diagnostic and pathogenetic implications of urinary coproporphyrin excretion in the Dubin-Johnson syndrome. Hepato-gastroenterol. 1990; 37: 147–151

    CAS  Google Scholar 

  12. Gentile, S., Marmo, R., Persico, M., Faccenda, F., Orlando, C., Rubba, P.: Dissociation between vascular and metabolic effects of nicotinic acid Gilbert’s syndrome. Clin. Physiol. 1990; 10: 171–178

    CAS  PubMed  Google Scholar 

  13. Gilbert, N.A., Lereboullet, P.: La cholémie simple familiale. Sem. Méd. Paris 1901; 21: 241–243

    Google Scholar 

  14. Gilbert, N.A., Lereboullet, P., Herscher, M.: Les trois cholémies congénitales. Bull. Mem. Soc. Med. Hop. Paris 1907; 24: 1203–1210

    Google Scholar 

  15. Gollan, J.L., Huang, S.M., Billing, B.H., Sherlock, S.: Prolonged survival in three brothers with severe typ 2 Crigler-Najjar syndrome. Ultrastructural and metabolic studies. Gastroenterology 1975; 68: 1543–1555

    CAS  PubMed  Google Scholar 

  16. Green, R.M., Gollan, J.L.: Crigler-Najjar disease type 1: therapeutic approaches to genetic liver diseases into the next century. Gastroenterology 1997; 112: 649–651

    CrossRef  CAS  PubMed  Google Scholar 

  17. Grunebaum, E., Amir, J., Merlob, P., Mimouni, M., Varsano, I.: Breast milk jaundice: natural history, familial incidence and late neurodevelopmental outcome of the infant. Eur. J. Pediat. 1991; 150: 267–270

    CrossRef  CAS  Google Scholar 

  18. Hashimoto, K., Uchiumi, T., Konno, T, Ebihara, T., Nakamura, T., Wada, M., Sakisaka, S., Maniwa, F., Amachi, T., Ueda, K., Kuwano, M.: Trafficking and functional defects by mutations of the ATP-binding domains in MRP 2 in patients with Dubin-Johnson syndrome. Hepatology 2002; 36: 1236–1245

    CrossRef  CAS  PubMed  Google Scholar 

  19. Horak, J., Pokorna, B., Mertl, L., Kostihova, E., Trunecke, P.: The nicotinic acid test in the evaluation of unconjugated hyperbilirubinemia. Z. Gastroenterol. 1989; 27: 629–632

    CAS  PubMed  Google Scholar 

  20. Huang, P.W.H., Rozdilsky, B., Gerrard, J.W., Goluboff, N., Holman, G.H.: Crigler-Najjar syndrome in four of five siblings with postmortem findings in one. Arch. Pathol. 1970; 90: 536–542

    CAS  PubMed  Google Scholar 

  21. Huang, C.S., Chang, P.F., Huang, M.J., Chen, E.S., Hung, K.L., Tsou, K.I.: Relationship between bilirubin UDP-glucuronosyl transferase 1A1 gene and neonatal hyperbilirubinemia. Pediatr. Res. 2002; 52: 601–605

    CrossRef  CAS  PubMed  Google Scholar 

  22. Jansen, P.L.M., Oude Elferink, R.P.J.: Hereditary hyperbilirubinemia: a molecular and mechanistic approach. Semin. Liver Dis. 1988; 8: 168–178

    CAS  PubMed  Google Scholar 

  23. Kaplan, M., Hammerman, C., Stevenson, D.K., Vreman, H.J., Muraca, M.: Hemolysis in Gilbert’s syndrome. Hepatology 2002; 36: 764–765

    Google Scholar 

  24. Kimura, A., Ushijima, K., Kage, M., Mahara, R., Tohma, M., Inokuchi, T., Shibao, K., Tanaka, N., Fujisawa, T., Ono, E., Yamashita, F.: Neonatal Dubin-Johnson syndrome with severe cholestasis: effective phenobarbital therapy. Acta Paediatr. Scand. 1991; 80: 381–385

    CAS  PubMed  Google Scholar 

  25. Kivilahan, C., James, E.J.P.: The natural history of neonatal jaundice. Pediatrics 1984; 74: 364–370

    Google Scholar 

  26. Kuntz, H.-D., Femfert, U., May, B.: Leberfunktion und Arzneimittelmetabolismus beim M. Gilbert. Z. Gastroenterol. 1986; 24: 29–30

    Google Scholar 

  27. Labrune, P.H., Myara, A., Francoual, J., Trivin, F., Odievre, M.: Cerebellar symproms as the presenting manifestations of bilirubin encephalopathy in children with Crigler-Najjar type I disease. Pediatrics 1992; 89: 768–770

    CAS  PubMed  Google Scholar 

  28. Lieverse, A.G., van Essen, G.G., Beukeveld, G.J.J., Gazendam, J., Dompeling, E.C., ten Kate, L.P., van Belle, S.A., Weits, J.: Familial increased serum intestinal alkaline phosphatase: a new variant associated with Gilbert’s syndrome. J. Clin. Pathol. 1990; 43: 125–128

    CAS  PubMed  Google Scholar 

  29. Lucey, J.F., Arias, I.M., McKay, R.J. jr.: Transient familial neonatal hyperbilirubinemia. Amer. J. Dis. Child. 1960; 100: 787–789

    Google Scholar 

  30. Maisels, J.M.: Neonatal jaundice. Semin. Liver dis. 1988; 8: 148–162

    CAS  PubMed  Google Scholar 

  31. Martin, J.F., Vierling, J.M., Wolkoff, A.W., Scharschmidt, B.F., Vergalla, J., Waggoner, J.G., Berk, P.D.: Abnormal hepatic transport of indocyanine green in Gilbert’s syndrome. Gastroenterology 1976; 70: 385–391

    CAS  PubMed  Google Scholar 

  32. Mendez-Sanchez, N., Gonzalez, V., Flores, A., Martinez, M., Graef, A., Uribe, M.: Delayed gastric emptying in subjects with Gilbert’s syndrome. Hepato-Gastroenterol. 2001; 48: 1183–1185

    CAS  Google Scholar 

  33. Meulengracht, E.: Icterus intermittens juvenilis. (Chronischer intermittierender juveniler Subikterus). Klin. Wschr. 1939; 18: 118–121

    CrossRef  Google Scholar 

  34. Murthy, G.D., Byron, D., Shoemaker, D., Visweswariah, H., Pasquale, D.: The utility of rifampicin in diagnosing Gilbert’s syndrome. Amer. J. Gastroenterol. 2001; 96: 1150–1154

    CAS  Google Scholar 

  35. Newman, Th.B., Easterling, M.J., Goldman, E.S., Stevenson, D.K.: Laboratory evaluation of jaundice in newborns. Amer. J. Dis. Child. 1990; 144: 364–368

    CAS  PubMed  Google Scholar 

  36. Nowicki, M.J., Poley, J.R.: The hereditary hyperbilirubinaemias. Baill. Clin. Gastroenterol. 1998; 12: 355–367

    CAS  Google Scholar 

  37. Pinos, T., Constansa, J.M., Palacin, A., Figueras, C.: A new diagnostic approach to the Dubin-Johnson syndrome. Amer. J. Gastroenterol. 1990; 85: 91–93

    CAS  Google Scholar 

  38. Robertson, K.J., Clarke, D., Sutherland, L., Wooster, R., Coughtrie, M.W.H., Burchell, B.: Investigation of the molecular basis of the genetic deficiency of UDP-glucuronosyltransferase in Crigler-Najjar syndrome. J. Inher. Metab. Dis. 1991; 14: 563–579

    CAS  PubMed  Google Scholar 

  39. Röllinghoff, W., Paumgartner, G., Preisig, R.: Nicotinic acid test in the diagnosis of Gilbert’s syndrome: correlation with bilirubin clearance. Gut 1981; 22: 663–668

    PubMed  Google Scholar 

  40. Rotor, A.B., Manahan, L., Florentin, A.: Familial non-hemolytic jaundice with direct van den Berg reaction. Acta Med. Philipp. 1948; 5: 37–49

    Google Scholar 

  41. Rubaltelli, F.F., Griffith, P.F.: Managament of neonatal hyperbilirubinaemia and prevention of kernicterus. Drugs 1992; 43: 864–872

    CAS  PubMed  Google Scholar 

  42. Seligsohn, U., Shani, M.: The Dubin-Johnson syndrome and pregnancy. Acta Hepato-Gastroenterol. 1977; 24: 167–169

    CAS  Google Scholar 

  43. Shimizu, Y., Naruto, H., Ida, S., Kohakura, M.: Urinary coproporphyrin isomers in Rotor’s syndrome. A study in eight families. Hepatology 1981; 1: 173–178

    CAS  PubMed  Google Scholar 

  44. Sinaasappel, M., Jansen, P.L.M.: The differential diagnosis of Crigler-Najjar disease, types 1 and 2, by bile pigment analysis. Gastroenterology 1991; 100: 783–789

    CAS  PubMed  Google Scholar 

  45. Sokal, E.M., Silva, E.S., Hermans, D., Reding, R., De Ville de Goyet, J., Buts, J.R., Otte, J.B.: Orthotopic liver transplantation for Crigler-Najjar type 1 disease in six children. Transplantation 1995; 60: 1095–1098

    CAS  PubMed  Google Scholar 

  46. South, M., Butt, W.: Treatment of neonatal hyperbilirubinaemia by plasmapheresis. Intensive Care Med. 1992; 18: 373–374

    CrossRef  CAS  PubMed  Google Scholar 

  47. Sprinz, H., Nelson, R.S.: Persistent nonhemolytic hyperbilirubinemia associated with lipochrome-like pigment on liver cells: report of 4 cases. Ann. Intern. 1954; 41: 952–962

    CAS  Google Scholar 

  48. Tazawa, Y., Abukawa, D., Nakagawa, M., Yamada, M.: Abnormal results of biochemical liver function tests in breast-fed infants with prolonged indirect hyperbilirubinemia. Eur. J. Pediatr. 1991; 150: 310–313

    CrossRef  CAS  PubMed  Google Scholar 

  49. Varma, R.R., Grainger, J.M., Scheuer, P.J.: A case of the Dubin-Johnson syndrome complicated by acute hepatitis. Gut 1970; 11: 817–821

    CAS  PubMed  Google Scholar 

  50. Ware, A.J., Eigenbrodt, E. Huang, P.W.H., Rozdilsky, B., Gerrard, J.W., Goluboff, N., Holman, G.H.: Crigler-Najjar syndrome in four of five siblings with postmortem findings in one. Arch. Pathol. 1970; 90: 536–542

    Google Scholar 

  51. H., Shorey, J., Combes, B.: Viral hepatitis complicating the Dubin-Johnson syndrome. Gastroenterology 1972; 63: 331–339

    PubMed  Google Scholar 

  52. Wolkoff, A.W., Wolpert, E., Pascasio, F.N., Arias, I.M.: Rotor’s syndrome. A distinct inheritable pathophysiologic entity. Amer. J. Med. 1976; 60: 173–179

    CAS  PubMed  Google Scholar 

  53. Zimniak, P.: Dubin-Johnson and Rotor syndromes: molecular basis and pathogenesis. Semin. Liver Dis. 1993; 13: 248–260

    CAS  PubMed  Google Scholar 

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(2006). Jaundice. In: Hepatology Principles and Practice. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-28977-1_12

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  • DOI: https://doi.org/10.1007/3-540-28977-1_12

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