Skip to main content
SpringerLink
Log in

Proteomics: Die Zukunft hat schon begonnen

  • Conference paper
Fortschritte der praktischen Dermatologie und Venerologie

Part of the book series: Fortschritte der praktischen Dermatologie und Venerologie ((DERMATOLOGIE,volume 19))

  • 214 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 109.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Ahram M, Best CJ, Flaig MJ, Gillespie JW, Leiva IM, Chuaqui RF, Zhou G, Shu H, Duray PH, Linehan WM, Raffeld M, Ornstein DK, Zhao Y, Petricoin EF, 3rd, Emmert-Buck MR (2002) Proteomic analysis of human prostate cancer. Mol Carcinog 33: 9–15

    Article  CAS  PubMed  Google Scholar 

  2. Ahram M, Emmert-Buck MR (2003) Approaches to proteomic analysis of human tumors. Methods Mol Biol 222: 375–384

    CAS  PubMed  Google Scholar 

  3. Ahram M, Flaig MJ, Gillespie JW, Duray PH, Linehan WM, Ornstein DK, Niu S, Zhao Y, Petricoin EF, 3rd, Emmert-Buck MR (2003) Evaluation of ethanol-fixed, paraffin-embedded tissues for proteomic applications. Proteomics 3: 413–421

    Article  CAS  PubMed  Google Scholar 

  4. Anderson NL, Anderson NG (1998) Proteome and proteomics: new technologies, new concepts, and new words. Electrophoresis 19: 1853–1861

    Article  CAS  PubMed  Google Scholar 

  5. Baron JM, Merk HF, Heise R (2003) Arraytechnologien in der Dermatopharmazie und Allergologie. Hautarzt 54: 315–320

    CAS  PubMed  Google Scholar 

  6. Best CJ, Gillespie JW, Englert CR, Swalwell JI, Pfeifer J, Krizman DB, Petricoin EF, Liotta LA, Emmert-Buck MR (2000) New approaches to molecular profiling of tissue samples. Anal Cell Pathol 20: 1–6

    Article  CAS  PubMed  Google Scholar 

  7. Bichsel VE, Liotta LA, Petricoin EF, 3rd (2001) Cancer proteomics: from biomarker discovery to signal pathway profiling. Cancer J 7: 69–78

    CAS  PubMed  Google Scholar 

  8. Braunschweig T, Chung JY, Hewitt SM (2004) Perspectives in tissue microarrays. Comb Chem High Throughput Screen 7: 575–585

    Article  CAS  PubMed  Google Scholar 

  9. Chuaqui RF, Bonner RF, Best CJ, Gillespie JW, Flaig MJ, Hewitt SM, Phillips JL, Krizman DB, Tangrea MA, Ahram M, Linehan WM, Knezevic V, Emmert-Buck MR (2002) Post-analysis follow-up and validation of microarray experiments. Nat Genet 32: 509–514

    Article  CAS  PubMed  Google Scholar 

  10. Emmert-Buck MR, Bonner RF, Smith PD, Chuaqui RF, Zhuang Z, Goldstein SR, Weiss RA, Liotta LA (1996) Laser capture microdissection. Science 274: 998–1001

    Article  CAS  PubMed  Google Scholar 

  11. Emmert-Buck MR, Strausberg RL, Krizman DB, Bonaldo MF, Bonner RF, Bostwick DG, Brown MR, Buetow KH, Chuaqui RF, Cole KA, Duray PH, Englert CR, Gillespie JW, Greenhut S, Grouse L, Hillier LW, Katz KS, Klausner RD, Kuznetzov V, Lash AE, Lennon G, Linehan WM, Liotta LA, Marra MA, Munson PJ, Ornstein DK, Prabhu VV, Prang C, Schuler GD, Soares MB, Tolstoshev CM, Vocke CD, Waterston RH (2000) Molecular profiling of clinical tissues specimens: feasibility and applications. J Mol Diagn 2: 60–66

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  12. Englert CR, Baibakov GV, Emmert-Buck MR (2000) Layered expression scanning: rapid molecular profiling of tumor samples. Cancer Res 60: 1526–1530

    CAS  PubMed  Google Scholar 

  13. Espina V, Mehta AI, Winters ME, Calvert V, Wulfkuhle J, Petricoin EF 3rd, Liotta LA (2003) Protein microarrays: molecular profiling technologies for clinical specimens. Proteomics 3: 2091–2100

    Article  CAS  PubMed  Google Scholar 

  14. Gillespie JW, Gannot G, Tangrea MA, Ahram M, Best CJ, Bichsel VE, Petricoin EF, Emmert-Buck MR, Chuaqui RF (2004) Molecular profiling of cancer. Toxicol Pathol 32:67–71

    Article  CAS  PubMed  Google Scholar 

  15. Grubb RL, Calvert VS, Wulkuhle JD, Paweletz CP, Linehan WM, Phillips JL, Chuaqui R, Valasco A, Gillespie J, Emmert-Buck M, Liotta LA, Petricoin EF (2003) Signal pathway profiling of prostate cancer using reverse phase protein arrays. Proteomics 3: 2142–2146

    Article  CAS  PubMed  Google Scholar 

  16. Gygi SP, Rochon Y, Franza BR, Aebersold R (1999) Correlation between protein and mRNA abundance in yeast. Mol Cell Biol 19: 1720–1730

    CAS  PubMed Central  PubMed  Google Scholar 

  17. Haynes PA, Gygi SP, Figeys D, Aebersold R (1998) Proteome analysis: biological assay or data archive? Electrophoresis 19: 1862–1871

    Article  CAS  PubMed  Google Scholar 

  18. Leiva IM, Emmert-Buck MR, Gillespie JW (2003) Handling of clinical tissue specimens for molecular profiling studies. Curr Issues Mol Biol 5: 27–35

    CAS  PubMed  Google Scholar 

  19. Liotta L, Petricoin E (2000) Molecular profiling of human cancer. Nat Rev Genet 1: 48–56

    Article  CAS  PubMed  Google Scholar 

  20. Liotta LA, Kohn EC, Petricoin EF (2001) Clinical proteomics: personalized molecular medicine. JAMA 286: 2211–2214

    Article  CAS  PubMed  Google Scholar 

  21. Paweletz CP, Charboneau L, Bichsel VE, Simone NL, Chen T, Gillespie JW, Emmert-Buck MR, Roth MJ, Petricoin IE, Liotta LA (2001) Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front. Oncogene 20: 1981–1989

    Article  CAS  PubMed  Google Scholar 

  22. Paweletz CP, Ornstein DK, Roth MJ, Bichsel VE, Gillespie JW, Calvert VS, Vocke CD, Hewitt SM, Duray PH, Herring J, Wang QH, Hu N, Linehan WM, Taylor PR, Liotta LA, Emmert-Buck MR, Petricoin EF 3rd (2000) Loss of annexin 1 correlates with early onset of tumorigenesis in esophageal and prostate carcinoma. Cancer Res 60: 6293–6297

    CAS  PubMed  Google Scholar 

  23. Petricoin EF, Wulfkuhle J, Espina V, Liotta LA (2004) Clinical proteomics: revolutionizing disease detection and patient tailoring therapy. J Proteome Res 3: 209–217

    Article  CAS  PubMed  Google Scholar 

  24. Petricoin EF, Ardekani AM, Hitt BA, Levine PJ, Fusaro VA, Steinberg SM, Mills GB, Simone C, Fishman DA, Kohn EC, Liotta LA (2002) Use of proteomic patterns in serum to identify ovarian cancer. Lancet 359: 572–577

    Article  CAS  PubMed  Google Scholar 

  25. Petricoin EF, Liotta LA (2004) SELDI-TOF-based serum proteomic pattern diagnostics for early detection of cancer. Curr Opin Biotechnol 15: 24–30

    Article  CAS  PubMed  Google Scholar 

  26. Rosenblatt KP, Bryant-Greenwood P, Killian JK, Mehta A, Geho D, Espina V, Petricoin EF, 3rd, Liotta LA (2004) Serum proteomics in cancer diagnosis and management. Annu Rev Med 55: 97–112

    Article  CAS  PubMed  Google Scholar 

  27. Stoeckli M, Chaurand P, Hallahan DE, Caprioli RM (2001) Imaging mass spectrometry: a new technology for the analysis of protein expression in mammalian tissues. Nat Med 7: 493–496

    Article  CAS  PubMed  Google Scholar 

  28. Tangrea MA, Flaig MJ, Ramesh A, Best CJ, Baibakov GV, Hewitt SM, Mitchell CD, Hartmann DP, Knezevic V, Emmert-Buck MR, Chuaqui RF (2003) Layered expression scanning: multiplex analysis of RNA and protein gels. Biotechniques 35: 1280–1285

    CAS  PubMed  Google Scholar 

  29. Tyers M, Mann M (2003) From genomics to proteomics. Nature 422: 193–197

    Article  CAS  PubMed  Google Scholar 

  30. Yazdi AS, Puchta U, Flaig MJ, Sander CA (2004) Lasercapture microdissection: applications in routine molecular dermatopathology. J Cutan Pathol 31: 465–470

    Article  PubMed  Google Scholar 

  31. Zhou G, Li H, DeCamp D, Chen S, Shu H, Gong Y, Flaig M, Gillespie JW, Hu N, Taylor PR, Emmert-Buck MR, Liotta LA, Petricoin EF, 3rd, Zhao Y (2002) 2D differential in-gel electrophoresis for the identification of esophageal squamous cell cancer-specific protein markers. Mol Cell Proteomics 1: 117–124

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Klinik und Poliklinik für Dermatologie und Allergologie, Klinikum der Universität München, Frauenlobstraße 9–11, D-80337, München, Germany

    Michael J. Flaig (Dr. med.)

  2. Institut für Pathologie, Universitätsklinikum Aachen der RWTH, Pauwelsstraße 30, D-52074, Aachen, Germany

    Rene C. Krieg (Dr. med.)

Authors
  1. Michael J. Flaig
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Rene C. Krieg
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Gerd Plewig (Prof. Dr. med. Dr. h.c.)Peter Kaudewitz (Prof. Dr. med.)Christian A. Sander (Priv.-Doz. Dr. med.)

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Flaig, M.J., Krieg, R.C. (2005). Proteomics: Die Zukunft hat schon begonnen. In: Plewig, G., Kaudewitz, P., Sander, C.A. (eds) Fortschritte der praktischen Dermatologie und Venerologie. Fortschritte der praktischen Dermatologie und Venerologie, vol 19. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-28691-8_13

Download citation

  • DOI: https://doi.org/10.1007/3-540-28691-8_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-21055-9

  • Online ISBN: 978-3-540-28691-2

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics

Search

Navigation