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Percutaneous Ablation of Hepatocellular Carcinoma

  • Riccardo Lencioni
  • Clodilde Della Pina
  • Laura Crocetti
  • Dania Cioni
Chapter
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 167)

7.5 Conclusions

Several percutaneous techniques have been developed to treat nonsurgical patients with liver malignancies. These minimally invasive procedures can achieve effective and reproducible tumor destruction with acceptable morbidity. Percutaneous ablation is accepted as the best therapeutic choice for patients with early-stage HCC when resection or transplantation are precluded. PEI is the seminal technique for local ablation of HCC, and may achieve a 5-year survival rate of 50% in selected Child A patients. RF ablation constitutes the most assessed alternative technique. On the basis of the identified evidence, RF ablation seems to reach higher cumulative survival and recurrence-free survival rates compared with PEI. RF ablation has also become a viable treatment method for patients with limited hepatic metastatic disease from colorectal cancer who are not eligible for surgical resection. Further trials are needed to establish the clinical efficacy of the other percutaneous treatments. An appropriate use of percutaneous ablation techniques can only be done when the therapeutic strategy is decided by a multidisciplinary team and is tailored to the individual patient and to the features of the disease.

Keywords

Radiofrequency Ablation Percutaneous Ethanol Injection Percutaneous Ablation Small Hepatocellular Carcinoma Percutaneous Radiofrequency Ablation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2006

Authors and Affiliations

  • Riccardo Lencioni
    • 1
  • Clodilde Della Pina
  • Laura Crocetti
  • Dania Cioni
  1. 1.Division of Diagnostic and Interventional RadiologyUniversity of PisaPisaItaly

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