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Growth, Differentiation and Sexuality pp 123–139Cite as

Re-Wiring the Network: Understanding the Mechanism and Function of Anastomosis in Filamentous Ascomycete Fungi

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Part of the book series: The Mycota ((MYCOTA,volume 1))

VII. Conclusion

Anastomosis captured the imagination of early mycologists, and numerous studies describing the morphology of hyphal fusion in ascomycete and basidiomycete species have been published. However, work describing mutant phenotypes or the molecular function of genes and proteins required for anastomosis in filamentous fungi has largely been ignored. Advances in cell biology techniques and live cell imaging of the hyphal fusion process will hopefully lead to an increased awareness and interest in this important aspect of filamentous fungal biology. In addition, advances in molecular and genetic tractability of a variety of filamentous fungi, and the availability of genome sequences will lead to in-depth comparative analyses that will, hopefully, begin to reveal the rich tapestry of inter- and intrahyphal communication that accompanies both developmental and morphogenetic processes. Many questions regarding the mechanism and function of hyphal anastomosis remain unanswered. What are the diffusible chemotropic molecules responsible for causing fusion-competent hyphae to grow toward each other, and how do they regulate Spitzenkörper behavior? Is the signal transduction machinery involved in regulating hyphal homing and fusion between conidial germlings the same or different to that involved in homing and fusion between hyphae in the colony interior? How similar or different are the signaling and fusion machineries involved in vegetative stages vis-à-vis those involved in sexual stages of the life cycle? Finally, what selective advantage maintains the capacity of germlings and hyphae to undergo anastomosis, and under what conditions?

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Authors and Affiliations

  1. Department of Plant and Microbial Biology, The University of California, Berkeley, CA, 94720-3102, USA

    N. L. Glass & A. Fleissner

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  1. N. L. Glass
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  2. A. Fleissner
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  1. Institut für Forstbotanik, Abteilung für Molekulare Holzbiotechnologie, Georg-August-Universität Göttingen, Büsgenweg 2, 37077, Göttingen, Germany

    Ursula Kües

  2. Institut für Angewandte Biowissenschaften, Abteilung für Angewandte Mikrobiologie, Universität Karlsruhe, Hertzstr. 16, 76187, Karlsruhe, Germany

    Reinhard Fischer

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Glass, N.L., Fleissner, A. (2006). Re-Wiring the Network: Understanding the Mechanism and Function of Anastomosis in Filamentous Ascomycete Fungi. In: Kües, U., Fischer, R. (eds) Growth, Differentiation and Sexuality. The Mycota, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-28135-5_7

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