Skip to main content

Acetylsalicylic acid

  • Chapter
Drugs and Poisons in Humans
  • 3197 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 259.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 329.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Japan Poison Center (ed) (2000) Poisoning Accidents and their Countermeasures with Special Reference to Actual Cases, revised edn. Jiho Inc., Tokyo, pp 127–131 (in Japanese)

    Google Scholar 

  2. Blair D, Rumack BH, Peterson RG (1978) Analysis for salicylic acid in serum by high-performance liquid chromatography. Clin Chem 24:1543–1544

    PubMed  CAS  Google Scholar 

  3. Cham BE, Johns D, Bochner F et al. (1979) Simultaneous liquid-chromatographic quantitation of salicylic acid, salicyluric acid, and gentisic acid in plasma. Clin Chem 25:1420–1425

    PubMed  CAS  Google Scholar 

  4. Cham BE, Ross-Lee L, Bochner F et al. (1980) Measurement and pharmacokinetics of acetylsalicylic acid by a novel high performance liquid chromatographic assay. Ther Drug Monit 2:365–372

    PubMed  CAS  Google Scholar 

  5. Harrison LI, Funk ML, Ober RE (1980) High-pressure liquid chromatographic determination of salicylsalicylic acid, aspirin, and salicylic acid in human plasma and urine. J Pharm Sci 69:1268–1271

    PubMed  CAS  Google Scholar 

  6. Wahlin-Boll E, Brantmark B, Hanson A et al. (1981) High-pressure liquid chromatographic determination of acetylsalicylic acid, salicylic acid, diflunisal, indomethacin, indoprofen and indobufen. Eur J Clin Pharmacol 20:375–378

    PubMed  CAS  Google Scholar 

  7. Rumble RH, Roberts MS, Wanwimolruk S (1981) Determination of aspirin and its major metabolites in plasma by high-performance liquid chromatography without solvent extraction. J Chromatogr 225:252–260

    PubMed  CAS  Google Scholar 

  8. Buskin JN, Upton RA, Williams RL (1982) Improved liquid-chromatography of aspirin, salicylate, and salicyluric acid in plasma, with a modification for determining aspirin metabolites in urine. Clin Chem 28:1200–1203

    PubMed  CAS  Google Scholar 

  9. Reidl U (1983) Determination of acetylsalicylic acid and metabolites in biological fluids by high-performance liquid chromatography. J Chromatogr 272:325–331

    PubMed  CAS  Google Scholar 

  10. Bakar SK, Niazi S (1983) High-performance liquid chromatographic determination of aspirin and its metabolites in plasma and urine. J Pharm Sci 72:1020–1023

    PubMed  CAS  Google Scholar 

  11. O,Kruk RJ, Adams MA, Philp RB (1984) Rapid and sensitive determination of acetylsalicylic acid and its metabolites using reversed-phase high-performance liquid chromatography. J Chromatogr 310:343–352

    Google Scholar 

  12. Ogunbona FA (1986) Simultaneous liquid chromatographic determination of aspirin and the metabolites in human urine. J Chromatogr 377:471–474

    PubMed  CAS  Google Scholar 

  13. Siebert DM, Bochner F (1987) Determination of plasma aspirin and salicylic acid concentrations after low aspirin doses by high-performance liquid chromatography with post-column hydrolysis and fluorescence d etection. J Chromatogr 420:425–431

    PubMed  CAS  Google Scholar 

  14. Gaspari F, Locatelli M (1987) Determination of aspirin and salicylic acid in uremic patients plasma using reversed-phase high-performance liquid chromatography. Ther Drug Monit 9:243–247

    PubMed  CAS  Google Scholar 

  15. Legaz ME, Acitores E, Valverde F (1992) Determination of salicylic acid by HPLC in plasma and saliva from children with juvenile chronic arthritis. Tokai J Exp Clin Med 17:229–237

    PubMed  CAS  Google Scholar 

  16. Kees F, Jehnich D, Grobecker H (1996) Simultaneous determination of acetylsalicylic acid and salicylic acid in human plasma by high-performance liquid chromatography. J Chromatogr B 677:172–177

    Google Scholar 

  17. Krivosikova Z, Spustova V, Dzurik R (1996) A highly sensitive HPLC method for the simultaneous determination of acetylsalicylic, salicylic and salicyluric acids in biologic fluids: pharmacokinetic, metabolic and monitoring implications. Method Find Exp Clin Pharmacol 18:527–532

    CAS  Google Scholar 

  18. McMahon GP, Kelly MT (1998) Determination of aspirin and salicylic acid in human plasma by column-switching liquid chromatography using on-line solid-phase extraction. Anal Chem 70:409–414

    Article  PubMed  CAS  Google Scholar 

  19. Pirola R, Bareggi SR, De Benedittis G (1998) Determination of acetylsalicylic acid and salicylic acid in skin and plasma by high-performance liquid chromatography. J Chromatogr B 705:309–315

    CAS  Google Scholar 

  20. Walter LJ, Biggs DF, Coutts RT (1974) Simultaneous GLC estimation of salicylic acid and aspirin in plasma. J Pharm Sci 63:1754–1758

    PubMed  CAS  Google Scholar 

  21. Rance MJ, Jordan BJ, Nichols JD (1975) A simultaneous determination of acetylsalicylic acid, salicylic acid and salicylamide in plasma by gas liquid chromatography. J Pharm Pharmacol 27:425–429

    PubMed  CAS  Google Scholar 

  22. Tam YK, Au DS, Abbott FS (1979) Improved gas-liquid chromatographic-flame ionization detection assay of acetylsalicylic and salicylic acids. J Chromatogr 174:239–244

    Article  PubMed  CAS  Google Scholar 

  23. Belanger PM, Lalande M, Dore F et al. (1983) Rapid gas chromatographic determination of serum salicylates after silylation. J Pharm Sci 72:1092–1093

    PubMed  CAS  Google Scholar 

  24. Tsikas D, Tewes KS, Gutzki FM et al. (1998) Gas chromatographic-tandem mass spectrometric determination of acetylsalicylic acid in human plasma after oral administration of low-dose aspirin and guaimesal. J Chromatogr B 709:79–88

    CAS  Google Scholar 

  25. Goto Y, Makino K, Kataoka Y et al. (1998) Determination of salicylic acid in human serum with capillary zone electrophoresis. J Chromatogr B 706:329–335

    CAS  Google Scholar 

  26. Hansen SH, Jensen ME, Bjornsdottir I (1998) Assay of acetylsalicylic acid and three of its metabolites in human plasma and urine using non-aqueous capillary electrophoresis with reversed electroosmotic flow. J Pharm Biomed Anal 17:1155–1160

    Article  PubMed  CAS  Google Scholar 

  27. Zaugg S, Zhang X, Sweedler J et al. (2001) Determination of salicylate, gentisic acid and salicyluric acid in human urine by capillary electrophoresis with laser-induced fluorescence detection. J Chromatogr B 752:17–31

    CAS  Google Scholar 

  28. Naito H (2002) Poisoning of Industrial Products, Gases, Pesticides, Drugs, and Natural Toxin. Cases, Pathogenesis and its Treatment, 2nd edn. Nankodo, Tokyo, pp 354–355 (in Japanese)

    Google Scholar 

  29. Stead AH, Moffat AC (1983) A collection of therapeutic, toxic and fatal blood drug concentrations in man. Hum Toxicol 2:437–464

    PubMed  CAS  Google Scholar 

  30. Kwong TC, Laczin J, Baum J (1983) Self-poisoning with enteric-coated aspirin. Am J Clin Pathol 80:888–890

    PubMed  CAS  Google Scholar 

  31. Shkrum MJ, Gay RM, Hudson P (1989) Fatal iatrogenic salicylate intoxication in a long-term user of enteric-coated aspirin. Arch Pathol Lab Med 113:89–90

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Tanaka, E. (2005). Acetylsalicylic acid. In: Drugs and Poisons in Humans. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-27579-7_37

Download citation

  • DOI: https://doi.org/10.1007/3-540-27579-7_37

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-22277-4

  • Online ISBN: 978-3-540-27579-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics