The use of fibrin sealants in spinal surgery

  • D. Stoltze
  • J. Harms


Advances in anaesthesiology and intensive care therapy as well as improved instrumentation have been responsible for the rapid development of spinal surgery during the past 15 years. Pathological lesions of the spinal column often demand partial or complete resection of the vertebral body, which in turn requires its replacement. The extraordinary vascular supply of the vertebral body and of the spinal canal often results in profuse bleeding in the environs of sensitive structures such as the spinal cord. Electrocoagulation is of limited use, for fear of causing thermal injury. While preoperative embolisation can considerably reduce the tendency to bleed in such instances, bleeding from the epidural venous plexus may be unavoidable, e.g., in spondylitis and tumour surgery. In such instances, fibrin sealants have proved to be an excellent means of controlling diffuse bleeding. Fibrin sealants have also proved to be effective in controlling diffuse bleeding during cervical disc surgery, which occasionally necessitates preparation and identification of the vertebral artery. The resulting spectrum of applications of fibrin sealants are presented here.


Collagen matrix Fibrin sealants FloSeal matrix Haemostasis Spine surgery 


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Copyright information

© Springer-Verlag Berlin Heidelberg 2005

Authors and Affiliations

  • D. Stoltze
    • 1
  • J. Harms
    • 1
  1. 1.Abt. Orthopädie-Traumatologie I Wirbelsäulenchirurgie/Paraplegologie SRH KlinikumKarlsbad-Langensteinbach GmbHKarlsbadGermany

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