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Medical Retina pp 19–34Cite as

Fundus Autofluorescence Imaging

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Part of the Essentials in Ophthalmology book series (ESSENTIALS)

Summary

Ophthalmic imaging technology has revolutionized fundus examination. FAF imaging represents one of various novel tools and provides information over and above fundus photography, fluorescence angiography and optical coherence tomography. This noninvasive diagnostic tool visualizes age- and disease-related metabolic changes of the retinal pigment epithelium. The autofluorescence signal mainly derives from dominant fluorophores in lipofuscin granules of the RPE. Lipofuscin accumulation represents a common downstream pathogenetic pathway in many retinal and macular disease entities.Thus FAF imaging contributes significantly to our understanding of the pathophysiology and treatment of various retinal diseases.

Keywords

  • Retinal Pigment Epithelial Cell
  • Geographic Atrophy
  • Macular Pigment
  • Lipofuscin Granule
  • Fundus Autofluorescence

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Author information

Authors and Affiliations

  1. Department of Opthalmology, University of Bonn, Ernst-Abbe-Straße 2, 53127, Bonn, Germany

    Dr. Almut Bindewald, Dr. Felix Roth, Dr. Steffen Schmitz-Valckenberg, Priv.-Doz. Dr. Hendrik P.N. Scholl & Prof. Dr. Frank G. Holz

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  1. Dr. Almut Bindewald
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  2. Dr. Felix Roth
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  3. Dr. Steffen Schmitz-Valckenberg
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  4. Priv.-Doz. Dr. Hendrik P.N. Scholl
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  5. Prof. Dr. Frank G. Holz
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Editor information

Editors and Affiliations

  1. Department of Ophthalmology, University of Bonn, Ernst-Abbe-Straβe 2, 53127, Bonn, Germany

    Frank G. Holz MD (Professor of Ophthalmology) (Professor of Ophthalmology)

  2. Vitreous Retina-Macula Consultants of New York, 519 E 72nd St., Suite 203, New York, NY, 10021, USA

    Richard F. Spaide MD (Professor of Ophthalmology) (Professor of Ophthalmology)

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Bindewald, A., Roth, F., Schmitz-Valckenberg, S., Scholl, H.P., Holz, F.G. (2005). Fundus Autofluorescence Imaging. In: Holz, F.G., Spaide, R.F. (eds) Medical Retina. Essentials in Ophthalmology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-27272-0_2

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  • DOI: https://doi.org/10.1007/3-540-27272-0_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-22596-6

  • Online ISBN: 978-3-540-27272-4

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