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Medical Retina pp 165–181Cite as

Pharmacological Approaches to Age-Related Macular Degeneration

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Part of the Essentials in Ophthalmology book series (ESSENTIALS)

Summary

Based on the results of the ARED study, a prophylactic treatment with a combination of vitamin C, vitamin E, β-carotene, and zinc is recommended for patients meeting the fundoscopic criteria described as categories 3 and 4 in the study. For all other nutritional supplementation including lutein or zeaxanthin,which increase macular pigment density, there is as yet no proven efficacy with regard to the prevention of AMD. However, many new antiangiogenic therapies are currently under investigation in large multicentre trials and hold exciting potential for patients with neovascular AMD. Further insight into the angiogenic process and its inhibition may lead to more targets that may be transferred for use in patients with neovascular AMD.

Keywords

  • Retinal Pigment Epithelium
  • Pigment Epithelium Derive Factor
  • Macular Pigment
  • Choroidal Neovascular Membrane
  • Macular Pigment Density

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Authors and Affiliations

  1. Department of Ophthalmology, University of Bonn, Ernst-Abbe-Straße 2, 53127, Bonn, Germany

    Priv.-Doz. Dr. N. Eter, Dr. T. Krohne & Prof. Dr. F.G. Holz

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  1. Priv.-Doz. Dr. N. Eter
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  2. Dr. T. Krohne
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  3. Prof. Dr. F.G. Holz
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Editors and Affiliations

  1. Department of Ophthalmology, University of Bonn, Ernst-Abbe-Straβe 2, 53127, Bonn, Germany

    Frank G. Holz MD (Professor of Ophthalmology) (Professor of Ophthalmology)

  2. Vitreous Retina-Macula Consultants of New York, 519 E 72nd St., Suite 203, New York, NY, 10021, USA

    Richard F. Spaide MD (Professor of Ophthalmology) (Professor of Ophthalmology)

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© 2005 Springer-Verlag Berlin Heidelberg

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Eter, N., Krohne, T., Holz, F. (2005). Pharmacological Approaches to Age-Related Macular Degeneration. In: Holz, F.G., Spaide, R.F. (eds) Medical Retina. Essentials in Ophthalmology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-27272-0_10

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  • DOI: https://doi.org/10.1007/3-540-27272-0_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-22596-6

  • Online ISBN: 978-3-540-27272-4

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