Skip to main content

Assessment of Myocardial Blood Volume

  • Chapter
Book cover Contrast Media in Ultrasonography

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

  • 1071 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 259.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Anderson WD, Anderson WB, Seguin RJ (1988) Microvasculature of the bear heart demonstrated by scanning electron microscopy. Acta Anat 131:305–313

    PubMed  Google Scholar 

  • Bassingthwaighte JB, Yipintsoi T, Harvey RB (1974) Microvasculature of the dog left ventricular myocardium. Microvasc Res 7:229–249

    Article  PubMed  Google Scholar 

  • Belenkie I, Trabousi M, Hall C et al (1992) Rescue angioplasty during myocardial infarction has a beneficial effect on mortality: a tenable hypothesis. Can J Cardiol 8:357–362

    PubMed  Google Scholar 

  • Beller GA, Watson DD (1991) Physiological basis of myocardial perfusion imaging with the technetium-99m agents. Semin Nucl Med 21:173–181

    PubMed  Google Scholar 

  • Califf RM, O'Neill W, Stacks RS et al (1988) Failure of simple clinical measurements to predict perfusion status after intravenous thrombolysis. Ann Intern Med 108:658–662

    PubMed  Google Scholar 

  • Chilian WM, Harrison DG, Haws CW et al (1986) Adrenergic coronary tone during submaximal exercise in the dog is produced by circulating catecolatives. Evidence for adrenergic denervation supersensitity in the myocardium but not in coronary vessels. Circ Res 58(1)68–82

    PubMed  Google Scholar 

  • Coggins MP, Sklenar J, Le E et al (2001) Noninvasive prediction of ultimate infarct size at the time of acute coronary occlusion based on the extent and magnitude of collateral-derived myocardial blood flow. Circulation 104:2471–2477

    PubMed  Google Scholar 

  • Dittrich HC, Bales GL, Kuvelas T et al (1995) Myocardial contrast echocardiography in experimental coronary artery occlusion with a new intravenously administered contrast agent. J Am Soc Echocardogr 8:465–474

    Google Scholar 

  • Ellis SG, da Silva ER, Heyndrickx G et al (1994) Randomized comparison of rescue angioplasty with conservative management of patients with early failure of thrombolysis for acute anterior myocardial infarction. Circulation 90:2280–2284

    PubMed  Google Scholar 

  • Firschke C, Lindner JR, Goodman NC et al (1997a) Myocardial contrast echocardiography in acute myocardial infarction using aortic root injections of microbubbles in conjunction with harmonic imaging: potential application in the cardiac catheterization laboratory. J Am Coll Cardiol 29:207–216

    Article  PubMed  Google Scholar 

  • Firschke C, Lindner JR, Wei K et al (1997b) Myocardial perfusion imaging in the setting of coronary artery stenosis and acute myocardial infarction using venous injection of a second-generation echocardiographic contrast agent. Circulation 96:959–967

    PubMed  Google Scholar 

  • Friedman BJ, Grinberg OY, Isaacs KA et al (1995) Myocardial oxygen tension and relative capillary density in isolated perfused rat hearts. J Mol Cell Cardiol 27:2551–2558

    Article  PubMed  Google Scholar 

  • Gayeski TE, Honig CR (1991) Intracellular PO2 in individual cardiomyocytes in dogs, cats, rabbits, ferrets, and rats. Am J Physiol 260:H552–H531

    Google Scholar 

  • Glover DK, Okada RD (1990) Myocardial kinetics of Tc-MIBI in canine myocardium after dipyridamole. Circulation 81:628–637

    PubMed  Google Scholar 

  • Glover DK, Ruiz M, Edwards NC et al (1995) Comparison between 201Tl and 99mTc Sestamibi uptake during adenosine induced vasodilation as a function of coronary stenosis severity. Circulation 91:813–820

    PubMed  Google Scholar 

  • Gould KL, Lipscomb K (1974) Effects of coronary stenoses on coronary flow reserve and resistance. Am J Cardiol 34:48–55

    Article  PubMed  Google Scholar 

  • Grayburn PA, Erickson JM, Escobar J et al (1995) Peripheral intravenous myocardial contrast echocardiography using a 2% dodecafluoropentane emulsion: identification of myocardial risk area and infarct size in the canine model of ischemia. J Am Coll Cardiol 26:1340–1347

    Article  PubMed  Google Scholar 

  • Heinle SK, Noblin J, Goree-Best P et al (2000) Assessment of myocardial perfusion by harmonic power Doppler imaging at rest and during adenosine stress. Comparison with 99mTc-sestamibi SPECT imaging. Circulation 102:55–60

    PubMed  Google Scholar 

  • Ismail S, Jayaweera AR, Goodman NC et al (1995) Detection of coronary stenosesand quantification of the degree and spatial extent of blood flow mismatch during coronary hyperemia with myocardial contrast echocardiography. Circulation 91:821–830

    PubMed  Google Scholar 

  • Ito H, Okamura A, Iwakura K et al (1996a) Myocardial perfusion patterns related to thrombolysis in myocardial infarction perfusion grades after coronary angioplasty in patinets with acute anterior wall myocardial infarction. Circulation 93:1993–1999

    PubMed  Google Scholar 

  • Ito H, Maruyama A, Iwakura K (1996b) Clinical implications of the “no reflow” phenomenon. A predictor of complications and left ventricular remodeling in reperfused anterior wall myocardial infarction. Circulation 93:223–228

    PubMed  Google Scholar 

  • Iwakura K, Ito H, Takiuchi S et al (1996) Alternation in the coronary blood flow velocity pattern in patients with no reflow and reperfused acute myocardial infarction. Circulation 94:1269–1275

    PubMed  Google Scholar 

  • Jarhult J, Mellander S (1973) Autoregulation of capilalry hydrostatic pressure in skeletal muscle during regional arterial hypo-and hypertension. Acta Physiol Scand 91:32–41

    Google Scholar 

  • Jayaweera AR, Jayaweera AR, Wei K et al (1999) Fate of capillaries distal to a stenosis. Their role in determining coronary blood flow reserve. Am J Physiol 46:H2363–H2372

    Google Scholar 

  • Johnson Paul C (1986) Autoregulation of blood flow. Circ Res 59:483–495

    PubMed  Google Scholar 

  • Kassab GS, Lin DH, Fung YB (1993) Morphometry of pig coronary arterial trees. Am J Physiol 265:H350–H365

    PubMed  Google Scholar 

  • Kassab GS, Lin DH, Fung YB (1994a) Morphometry of the pig coronary venous system. Am J Physiol 267:H2100–2113

    PubMed  Google Scholar 

  • Kassab GS, Lin DH, Fung YB (1994b) Topology and dimensions of pig coronary capillary network. Am J Physiol 267:H319–H325

    PubMed  Google Scholar 

  • Kaul S, Pandian NG, Okada RD et al (1984) Contrast echocardiography in acute myocardial ischemia. I. In vivo determination of total left ventricular “area at risk”. J Am Coll Cardiol 4:1272–1282

    PubMed  Google Scholar 

  • Kaul S, Gillam L, Weyman AE (1985) Contrast echocardiography in acute myocardial ischemia. II. The effect of site of injection of contrast agent on the estimation of area at risk for necrosis after coronary occlusion. J Am Coll Cardiol 6:825–830

    PubMed  Google Scholar 

  • Kaul S, Pandian NG, Gillam LD et al (1986) Contrast echocardiography in acute myocardial ischemia. III. An in-vivo comparison of the extent of abnormal wall motion with the “area at risk” for necrosis. J Am Coll Cardiol 7:383–392

    PubMed  Google Scholar 

  • Kaul S, Pandian NG, Guerrero L et al (1987) Effects of selectively altering collateral driving pressure on regional perfusion and function in occluded coronary bed in the dog. Circ Res 61:77–85

    PubMed  Google Scholar 

  • Kaul S, Senior R, Dittrich H et al (1997) Detection of coronary artery disease using myocardial contrast echocardiography: comparison with 99mTc sestamibi single photon emission computed tomography. Circulation 96:785–792

    PubMed  Google Scholar 

  • Keller MW, Segal SS, Kaul S, Duling B (1989) The behaviour of sonicated albumin microbubbles within the microcirculation: a basis for their use during myocardial contrast echocardiography. Circ Res 65:458–467

    PubMed  Google Scholar 

  • Le DE, Bin JP, Coggins MP et al (2002) Relation between myocardial oxygen consumption and myocardial blood volume: a study using myocardial contrast echocardiography. J Am Soc Echocardiogr 15:857–863

    Article  PubMed  Google Scholar 

  • Lepper W, Hoffmann R, Kamp O et al (2000) Assessment of myocardial reperfusion by intravenous myocardial contrast echocardiography and coronary flow reserve after primary percutaneous transluminal coronary angiography in patients with acute myocardial infarction. Circulation 101:2368–2374

    PubMed  Google Scholar 

  • Levin DC (1974) Pathways and functional significance of the coronary collateral circulation. Circulation 50:831–837

    PubMed  Google Scholar 

  • Lindner JR, Firschke C, Wei K et al (1998) Myocardial perfusion characteristics and hemodynamic profile of MRX-115, a venous echocardiographic contrast agent, during acute myocardial infarction. J Am Soc Echocardiogr 11:36–46

    PubMed  Google Scholar 

  • Linka AZ, Sklenar J, Wei K et al (1998) Spatial distribution of microbubble velocity and concentration within the myocardium: insights into the transmural distribution of myocardial blood flow and volume. Circulation 98:1912–1920

    PubMed  Google Scholar 

  • Marcus ML (1983) Anatomy of the coronary vasculature. In: Marcus ML (ed) The coronary circulation in health and disease. McGraw-ill, New York, pp 3–21

    Google Scholar 

  • Maruoka Y, Tomoike H, Kawachi Y et al (1986) Relations between collateral flow and tissue salvage in the risk area after acute coronary occlusion in dogs: a topographical analysis. Br J Exp Pathol 67:33–42

    PubMed  Google Scholar 

  • Miller AP, Nanda NC (2004) Contrast echocardiography: new agents. Ultrasound Med Biol 30:425–434

    Article  PubMed  Google Scholar 

  • Piek J, Becker AE (1988) Collateral blood supply to the myocardium at risk in human myocardial infarction: a quantitative postmortem assessment. J Am Coll Cardiol 11:1290–1296

    PubMed  Google Scholar 

  • Porter TR, Li S, Kilzer K, Deligonul U (1997) Effect of significant two-vessel versus one-vessel coronary artery stenosis on myocardial contrast defects observed with intermittent harmonic imaging after intravenous contrast injection during dobutamine stress echocardiography. J Am Coll Cardiol 30:1399–1406

    Article  PubMed  Google Scholar 

  • Porter TR, Li S, Oster R, Deligonul U (1998) The clinical implications of no reflow demonstrated with intravenous perfluorocarbon containing microbubbles following restoration of thrombolysis in myocardial infarction (TIMI) 3 flow in patients with acute myocardial infarction. Am J Cardiol 82:1173–1177

    Article  PubMed  Google Scholar 

  • Reimer KA, Jennings RB (1979) The “wavefront phenomenon” of myocardial ischemic cell death. II. Transmural progression of necrosis within the framework of ischemic bed size (myocardium at risk) and collateral flow. Lab Invest 40:633–644

    PubMed  Google Scholar 

  • Rocchi G, Kasprzak JD, Galema TW et al (2001) Usefulness of power Doppler contrast echocardiography to identify reperfusion after acute myocardial infarction. Am J Cardiol 87:278–282

    Article  PubMed  Google Scholar 

  • Sabia PJ, Powers ER, Jayaweera AR et al (1992) Functional significance of collateral blood flow in patients with recent acute myocardial infarction: a study using myocardial contrast echocardiography. Circulation 85:2080–2089

    PubMed  Google Scholar 

  • Sakuma T, Hayashi Y, Sumii K et al (1998) Prediction of short-and intermediate-term prognoses of patients with acute myocardial infarction using myocardial contrast echocardiography one day after recanalization. J Am Coll Cardiol 32:890–897

    Article  PubMed  Google Scholar 

  • Skyba DM, Jayaweera AR, Goodman NC et al (1994) Quantification of myocardial perfusion with myocardial contrast echocardiography from left atrial injection of contrast: implications for venous injection. Circulation 90:1513–1521

    PubMed  Google Scholar 

  • Tillmanns H, Kuebler W (1984) What happens in the microcirculation? In: Hearse DJ, Yellon DM (eds) Approaches to myocardial infarct size limitation. Raven, New York

    Google Scholar 

  • Tillmans H, Leinberger H, Neumann FJ et al (1987) Myocardial microcirculation in the beating heart: in vivo microscopic studies. In: Spaan JAE, Bruschke AVG, Gittenberger-de Groot AC (eds) Coronary virculation. Nijhoff, Dordrecht, pp 88–94

    Google Scholar 

  • Tillmanns H, Steinhausen M, Leinberger H et al (1991) Hemodynamics of the coronary microcirculation during myocardial ischemia. Circulation (Suppl) IV:40

    Google Scholar 

  • Tschabitscher M (1984) Anatomy of coronary veins. In: Mohl W, Wolner E, Glogar D (eds) The coronary sinus: proceedings of the first international symposium on myocardial protection via the coronary sinus. Steinkopff, Darmstadt, pp 8–25

    Google Scholar 

  • Villanueva FS, Glasheen WP, Sklenar J, Kaul S (1993) Assessment of risk area during coronary occlusion and infarct size after reperfusion with myocardial contrast echocardiography using left and right atrial injections of contrast. Circulation 88:596–604

    PubMed  Google Scholar 

  • Wei K, Jayaweera AR, Firoozan S et al (1998a) Quantification of myocardial blood flow using ultrasound-induced destruction of microbubbles administered as a constant venous infusion. Circulation 97:473–483

    PubMed  Google Scholar 

  • Wei K, Jayaweera AR, Firoozan S et al (1998b) Basis for detection of stenosis using venous administration of microbubbles during myocardial contrast echocardiography: Bolus or continuous infusion? J Am Coll Cardiol 32:252–260

    Article  PubMed  Google Scholar 

  • Wei K (2001) Detection and quantification of coronary stenosis severity with myocardial contrast echocardiography. Prog Cardiovasc Dis 44:81–100

    Article  PubMed  Google Scholar 

  • Wei K, Le E, Bin JP, Coggins M et al (2001) Mechanism of reversible 99mTc-sestamibi perfusion defects during pharmacologically induced coronary vasodilation. Am J Physiol 280:H1896–H1904

    Google Scholar 

  • Wei K, Crouse L, Weiss J et al (2003) PB127 phase 2 trial results: detection of coronary disease with rest and dipyridamole stress myocardial contrast echocardiography compared to 99mTc-sestamibi single photon emission computed tomography. Am J Cardiol 91:1293–1298

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Wei, K. (2005). Assessment of Myocardial Blood Volume. In: Quaia, E. (eds) Contrast Media in Ultrasonography. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-27214-3_19

Download citation

  • DOI: https://doi.org/10.1007/3-540-27214-3_19

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-40740-9

  • Online ISBN: 978-3-540-27214-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics