Abstract
One of the major aspects of HIV dynamics is the appearance of resistant viral variants. An increasing number of studies is related to the occurrence of drug resistance in patients receiving different ARV (antiretroviral) therapy regimen.
In Romania the access to ARV’s started in 1995, but HAART (highly active antiretroviral therapy) could be used only from 1998 on. Taking into account the particularities of AIDS epidemics in Romania (predominance in children,horizontal way of contamination, evolution of more than 13 years of infection and last but not least the subtype F of HIV-1 infection) we studied the profile of resistance in 20 children and 4 adults that received different ARV’s regimens.
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References
Apetrei C, I. Loussert-Ajaka, G. Collin et al. HIV type 1 subtype F sequences in Romanian children and adults. AIDS Res. Hum. Retroviruses. 1997; 13: 363–365
Apetrei C, D. Descamps, G. Collin, et al. Human Immunodeficiency Virus Type 1 Subtype F Reverse Transcriptase Sequence and Drug Susceptibility. J.Virol. 1998; 72–5: 3534–3538
Shafer R.W. Genotyping Testing for Human Immunodeficiency Virus Type 1 Drug Resistance. Clin Microbiology Rev, 2002; 15/2: 247–277
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© 2005 Springer Medizin Verlag Heidelberg
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Costa, R. et al. (2005). HIV Resistance to Antiretroviral Therapy in Romania. In: Scharrer, I., Schramm, W. (eds) 34th Hemophilia Symposium. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-27022-1_27
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DOI: https://doi.org/10.1007/3-540-27022-1_27
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-22886-8
Online ISBN: 978-3-540-27022-5
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