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DO2/VO2 relationships

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Functional Hemodynamic Monitoring

Part of the book series: Update in Intensive Care and Emergency Medicine ((UICMSOFT,volume 42))

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References

  1. Cain SM (1977) Oxygen delivery and uptake in dogs during anemic and hypoxic hypoxia. J Appl Physiol 42:228–234

    PubMed  Google Scholar 

  2. Nelson DP, Beyer C, Samsel RW, Wood LDH, Schumacker PT(1987) Pathological supply dependence of O2 uptake during bacteremia in dogs. J Appl Physiol 63:1487–1492

    PubMed  Google Scholar 

  3. Van der Linden P, Gilbert E, Engelman E, Schmartz D, Vincent JL (1991) Effects of anesthetic agents on systemic critical O2 delivery. J Appl Physiol 71:83–93

    PubMed  Google Scholar 

  4. Zhang H, Spapen H, Benlabed M, Vincent JL (1993) Systemic oxygen extraction can be improved during repeated episodes of cardiac tamponade. J Crit Care 8:93–99

    Article  PubMed  Google Scholar 

  5. Samsel RW, Nelson DP, Sanders WM, Wood LDH, Schumacker PT(1988) Effect of endotoxin on systemic and skeletal muscle O2 extraction. J Appl Physiol 65:1377–1382

    PubMed  Google Scholar 

  6. Zhang H, Vincent JL (1993) Oxygen extraction is altered by endotoxin during tamponade-induced stagnant hypoxia in the dog. Circ Shock 40:168–176

    PubMed  Google Scholar 

  7. Ronco JJ, Fenwick JC, Tweeddale MG, et al (1993) Identification of the critical oxygen delivery for anaerobic metabolism in critically ill septic and nonseptic humans. JAMA 270:1724–1730

    Article  PubMed  Google Scholar 

  8. Bihari D, Smithies M, Gimson A, Tinker J (1987) The effects of vasodilation with prostacyclin on oxygen delivery and uptake in critically ill patients. N Engl J Med 317:397–403

    PubMed  Google Scholar 

  9. Haupt MT, Gilbert EM, Carlson RW (1985) Fluid loading increases oxygen consumption in septic patients with lactic acidosis. Am Rev Respir Dis 131:912–916

    PubMed  Google Scholar 

  10. Vincent JL, Roman A, De Backer D, Kahn RJ (1990) Oxygen uptake/supply dependency: Effects of short-term dobutamine infusion. Am Rev Respir Dis 142:2–8

    PubMed  Google Scholar 

  11. Bakker J, Vincent JL (1991) The oxygen supply dependency phenomenon is associated with increased blood lactate levels. J Crit Care 6:152–159

    Article  Google Scholar 

  12. Gilbert EM, Haupt MT, Mandanas RY, Huaringa AJ, Carlson RW (1986) The effect of fluid loading, blood transfusion and catecholamine infusion on oxygen delivery and consumption in patients with sepsis. Am Rev Respir Dis 134:873–878

    PubMed  Google Scholar 

  13. Stratton HH, Feustel PJ, Newell JC (1987) Regression of calculated variables in the presence of shared measurement error. J Appl Physiol 62:2083–2093

    PubMed  Google Scholar 

  14. Gore DC, Jahoor F, Hibbert JM, DeMaria EJ (1996) Lactic acidosis during sepsis is related to increased pyruvate production, not deficits in tissue oxygen availability. Ann Surg 224:97–102

    Article  PubMed  Google Scholar 

  15. Friedman G, De Backer D, Shahla M, Vincent JL (1998) Oxygen supply dependency can characterize septic shock. Intensive Care Med 24:118–123

    Article  PubMed  Google Scholar 

  16. De Backer D, Creteur J, Noordally O, Smail N, Gulbis B, Vincent JL (1998) Does hepatosplanchnic VO2/DO2 dependency exist in critically ill patients. Am J Respir Crit Care Med 157:1219–1225

    PubMed  Google Scholar 

  17. Silance PG, Simon C, Vincent JL (1994) The relation between cardiac index and oxygen extraction in acutely ill patients. Chest 105:1190–1197

    PubMed  Google Scholar 

  18. Bakker J, Coffernils M, Leon M, Gris P, Vincent JL (1991) Blood lactate levels are superior to oxygen derived variables in predicting outcome in human septic shock. Chest 99:956–962

    PubMed  Google Scholar 

  19. Shoemaker WC, Appel PL, Kram HB, Waxman K, Lee TS (1988) Prospective trial of supranormal values of survivors as therapeutic goals in high-risk surgical patients. Chest 94:1176–1186

    PubMed  Google Scholar 

  20. Shoemaker WC, Montgomery ES, Kaplan E, Elwyn DH (1973) Physiologic patterns in surviving and nonsurviving shock patients. Use of sequential cardiorespiratory variables in defining criteria for therapeutic goals and early warning of death. Arch Surg 106:630–636

    PubMed  Google Scholar 

  21. Yu M, Levy MM, Smith P, Takiguchi SA, Miyasaki A, Myers SA (1993) Effect of maximizing oxygen delivery on morbidity and mortality rates in critically ill patients: A prospective, randomized, controlled study. Crit Care Med 21:830–838

    PubMed  Google Scholar 

  22. Lobo SM, Salgado PF, Castillo VG, et al (2000) Effects of maximizing oxygen delivery on morbidity and mortality in high-risk surgical patients. Crit Care Med 28:3396–3404

    Article  PubMed  Google Scholar 

  23. Gattinoni L, Brazzi L, Pelosi P, et al (1995) A trial of goal-oriented hemodynamic therapy in critically ill patients. N Engl J Med 333:1025–1032

    Article  PubMed  Google Scholar 

  24. Hayes MA, Timmins AC, Yau EH, Palazzo M, Hinds CJ, Watson D (1994) Elevation of systemic oxygen delivery in the treatment of critically ill patients. N Engl J Med 330:1717–1722

    Article  PubMed  Google Scholar 

  25. Rivers E, Nguyen B, Havstad S, et al (2001) Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 345:1368–1377

    Article  PubMed  Google Scholar 

  26. Polonen P, Ruokonen E, Hippelainen M, Poyhonen M, Takala J (2000) A prospective, randomized study of goal-oriented hemodynamic therapy in cardiac surgical patients. Anesth Analg 90:1052–1059

    PubMed  Google Scholar 

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© 2005 Springer-Verlag Berlin Heidelberg

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Vincent, J.L. (2005). DO2/VO2 relationships. In: Pinsky, M.R., Payen, D. (eds) Functional Hemodynamic Monitoring. Update in Intensive Care and Emergency Medicine, vol 42. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-26900-2_20

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  • DOI: https://doi.org/10.1007/3-540-26900-2_20

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-22349-8

  • Online ISBN: 978-3-540-26900-7

  • eBook Packages: MedicineMedicine (R0)

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