Clinical Value of Intrathoracic Volumes from Transpulmonary Indicator Dilution

  • A. B. J. Groeneveld
  • R. M. B. G. E. Breukers
  • J. Verheij
Conference paper
Part of the Update in Intensive Care and Emergency Medicine book series (volume 42)


Cardiac Index Pulmonary Artery Catheter Fluid Responsiveness Stroke Volume Variation Right Ventricular Ejection Fraction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Girbes ARJ, Groeneveld ABJ (2000) Circulatory optimization ofthe patient with or at risk for shock. Clin Intensive Care 11:77–88Google Scholar
  2. 2.
    Stéphan F, Flahault A, Dieudonné N, Hollande J, Paillard F, Bonnet F (2001) Clinical evaluation ofcirculating blood volume in critically ill patients-contribution of a clinicalscoring system. Br J Anaesth 86:754–762CrossRefGoogle Scholar
  3. 3.
    Richard C, Warszawski J, Anguel N, et al. (2003) Early use ofthe pulmonary artery catheter and outcomes ofpatients with shock and acute respiratory distress syndrome. JAMA 290:2713–2720CrossRefPubMedGoogle Scholar
  4. 4.
    Bendjelid K, Romand JA (2003) Fluid responsiveness in mechanically ventilated patients: a review of indices used in intensive care. Intensive Care Med 29:352–360CrossRefPubMedGoogle Scholar
  5. 5.
    Schneider AJ, Teule GJJ, Groeneveld ABJ, et al. (1988) Biventricular performance during volume loading in patients with early septic shock, with emphasis on the right ventricle: a combined hemodynamic and radionuclide study. Am Heart J 116:103–112CrossRefPubMedGoogle Scholar
  6. 6.
    Greim CA, Roewer N, Apfel C, Laux G, Schulte am Esch J (1996) Relation of echocardiographic preload indices to stroke volume in critically ill patients with normal and low cardiac index. Intensive Care Med 23:411–416CrossRefGoogle Scholar
  7. 7.
    Tousignant CP, Walsh F, Mazer CD (2000) The use oftransesophageal echocardiography for preload assessment in critically ill patients. Anesth Analg 90:351–355CrossRefPubMedGoogle Scholar
  8. 8.
    Cheatham ML, Nelson LD, Chang MC, Safcsak K (1998)Right ventricular end-diastolic volume index as a predictor ofpreload status in patients on positive end-expiratory pressure. Crit Care Med 26:1801–1806PubMedGoogle Scholar
  9. 9.
    Gödje O, Peyerl M, Seebauer T, Lamm P, Mair H, Reichart B (1998) Central venous pressure, pulmonary capillary wedge pressure and intrathoracic blood volumes as preload indicators in cardiac surgery patients. Eur J Cardiothor Surg 13:533–540CrossRefGoogle Scholar
  10. 10.
    Wagner JG, Leatherman JW (1998) Right ventricular end-diastolic volume as a predictor of the heamodynamic response to a fluid challenge. Chest 113:1048–1054PubMedGoogle Scholar
  11. 11.
    Groeneveld ABJ, Berendsen RR, Schneider AJ, Pneumatikos IA, Stokkel LA, Thijs LG (2000) Effect of the mechanical ventilatory cycle on thermodilution right ventricular volumes and cardiac output. J Appl Physiol 89:89–96PubMedGoogle Scholar
  12. 12.
    Lichtwarck-Aschoff M, Zeravik J, Pfeiffer UJ (1992) Intrathoracic blood volume accurately reflects circulatory volume status in critically ill patients with mechanical ventilation. Intensive Care Med 18:142–147CrossRefPubMedGoogle Scholar
  13. 13.
    Godje O, Peyerl M, Seebauer T, Dewald O, Reichart B (1998) Reproducibility ofdouble indicator dilution measurements ofintrathoraci c blood volume compartments, extravascular lung water and liver function. Chest 113:1070–1077PubMedGoogle Scholar
  14. 14.
    Neumann P (1999) Extravascular lung water and intrathoracic blood volume: double versus single indicator dilution technique. Intensive Care Med 25:216–219CrossRefPubMedGoogle Scholar
  15. 15.
    Sakka SG, Rühl CC, Pfeiffer UJ, et al (2000) Assessment of cardiac preload and extravascular lung water by single transpulmonary thermodilution. Intensive Care Med 26:180–187CrossRefPubMedGoogle Scholar
  16. 16.
    Reuter DA, Felbinger TW, Moerstedt K, et al (2002) Intrathoracic blood volume index measured by thermodilution for preload monitoring after cardiac surgery. J Cardiothor Vasc Anaesth 16:191–195CrossRefGoogle Scholar
  17. 17.
    Wiesenack C, Prasser C, Keyl C, Rodig G (2001) Assessment ofintrathoraci c blood volume as an indicator ofcardiac preload: single transpulmonary thermodilution technique versus assessment ofpressure preload parameters from a pulmonary artery catheter. J Cardiothorac Vasc Anesth 15:584–588CrossRefPubMedGoogle Scholar
  18. 18.
    Mitchell JP, Schuller D, Calandrino S, Schuster DP (1992) Improved outcome based on fluid management in critically ill patients requiring pulmonary artery catheterization. Am Rev Respir Dis 145:990–998PubMedGoogle Scholar
  19. 19.
    Groeneveld ABJ, Verhey J (2004) Is pulmonary edema associated with a high extravascular thermal volume? Crit Care Med 32:899–901CrossRefPubMedGoogle Scholar
  20. 20.
    Gust R, Gottschalk A, Bauer H, Böttinger BW, Böhrer H, Martin E (1998) Cardiac output measurement by transpulmonary versus conventional thermodilution technique in intensive care patients after coronary artery bypass grafting. J Cardiothor Vasc Anesth 12:519–522CrossRefGoogle Scholar
  21. 21.
    Goedje O, Seebauer T, Peyerl M, Pfeiffer UJ, Reichart B (2000) Hemodynamic monitoring by double-indicator dilution technique in patients after orthotopic heart transplantation. Chest 118:775–781CrossRefPubMedGoogle Scholar
  22. 22.
    Della Rocca G, Costa MGG, Pompei L, Coccia C, Pietropaoli P (2002) Continuous and intermittent cardiac output measurement: pulmonary artery catheter versus aortic transpulmonary technique. Br J Anaesth 88:350–356CrossRefPubMedGoogle Scholar
  23. 23.
    DellaRocca G, Costa MG, Coccia C, Pompei L, Pietropaoli P (2002) Preload and haemodynamic assessment during liver transplantation: a comparison between the pulmonary artery catheter and transpulmonary indicator dilution techniques. Eur J Anaesthesiol 19:868–875PubMedGoogle Scholar
  24. 24.
    Della Rocca G, Costa GM, Coccia C, Pompei L, Di Marco P, Pietropaoli P (2002) Preload index: pulmonary occlusion pressure versus intrathoracic blood volume monitoring during lung transplantation. Anesth Analg 95:835–843CrossRefPubMedGoogle Scholar
  25. 25.
    Luecke T, Roth H, Herrman P, et al (2004) Assessment ofcardiac preload and left ventricular function under increasing levels of positive end-expiratory pressure. Intensive Care Med 30:119–126CrossRefPubMedGoogle Scholar
  26. 26.
    Schreiber T, Hüter L, Schwarzkopf K, et al (2001) Lung perfusion affects preload assessment and lung water calculation with the transpulmonary double indicator method. Intensive Care Med 27:1814–1818CrossRefPubMedGoogle Scholar
  27. 27.
    Lichtwarck-Aschoff M, Beale R, Pfeiffer UJ (1996) Central venous pressure, pulmonary artery occlusion pressure, intrathoracic blood volume, and right ventricular end-diastolic volumes as indicators of cardiac preload. J Crit Care 11:180–188CrossRefPubMedGoogle Scholar
  28. 28.
    Buhre N, Kazmaier S, Sonntag H, Weyland A (2001) Changes in cardiac output and intrathoracic blood volume: mathematical coupling of data ? Acta Anaesthesiol Scand 45:863–867CrossRefPubMedGoogle Scholar
  29. 29.
    Preisman S, Pfeiffer U, Lieberman N, Perel A (1997) New monitors of intravascular volume: a comparison ofarterial pressure waveform analysis and the intrathoracic blood volume. Intensive Care Med 23:651–657CrossRefPubMedGoogle Scholar
  30. 30.
    McLuckie A, Bihari D (2000) Investigating the relationship between intrathoracic blood volume index and cardiac index. Intensive Care Med 26:1376–1378CrossRefPubMedGoogle Scholar
  31. 31.
    Michard F, Alaya S, Zarka V, Bahloul M, Richard C, Teboul J-L (2003) Global end-diastolic volume as an indicator ofcardiac preload in patients with septic shock. Chest 124:1900–1908CrossRefPubMedGoogle Scholar
  32. 32.
    Hinder F, Poelaert JI, Schmidt C, et al (1998) Assessment ofcardiovascular volume status by transoesophageal echocardiography and dye dilution during cardiac surgery. Eur J Anaesthesiol 15:633–640PubMedGoogle Scholar
  33. 33.
    Buhre W, Buhre K, Kazmaier S, Sonntag H, Weyland A (2001) Assessment ofcardiac preload by indicator dilution and transoesophageal echocardiography. Eur J Anaesthesiol 18:662–667CrossRefPubMedGoogle Scholar
  34. 34.
    Reuter DA, Felbinger TW, Schmidt C, et al (2003) Trendelenburg positioning after cardiac surgery: effects on intrathoracic blood volume index and cardiac performance. Eur J Anaesthesiol 20:17–20CrossRefPubMedGoogle Scholar
  35. 35.
    Kisch H, Leucht S, Lichtwarck-Aschoff M, Pfeiffer UJ (1995) Accuracy and reproducibility of the measurement ofactively circulating blood volume with an integrated fiberoptic monitoring system. Crit Care Med 23:885–893CrossRefPubMedGoogle Scholar
  36. 36.
    Brock H, HGabriel C, Bibl D, Necek S (2002) Monitoring intravascular volumes for postoperative volume therapy. Eur J Anaesthesiol 19:288–294PubMedGoogle Scholar
  37. 37.
    Buhre W, Weyland A, Schorn B, et al (1999) Changes in central venous pressure and pulmonary capillary wedge pressure do not indicate changes in right and left heart volume in patients undergoing coronary artery bypass surgery. Eur J Anaesthesiol 16:11–17CrossRefPubMedGoogle Scholar
  38. 38.
    Mundigler G, Heinze G, Zehetgruber M, Gabriel H, Siostrzonek P (2000) Limitations of the transpulmonary indicator dilution method for assessment of preload changes in critically ill patients with reduced left ventricular function. Crit Care Med 28:2231–2237CrossRefPubMedGoogle Scholar
  39. 39.
    Sakka SG, Bredle DL, Reinhart K, Meier-Hellman A (1999) Comparison between intrathoracic blood volume and cardiac filling pressure in the early phase of hemodynamic instability of patients with sepsis or septic shock. J Crit Care 14:78–83CrossRefPubMedGoogle Scholar
  40. 40.
    Reuter DA, Felbinger TW, Schmidt C, et al (2002) Stroke volume variations for assessment of cardiac responsiveness to volume loading in mechnically ventilated patients after cardiac surgery. Intensive Care Med 28:392–398CrossRefPubMedGoogle Scholar
  41. 41.
    Thasler WE, Bein T, Jauch K-W (2002) Perioperative effects of hepatic resection surgery on hemodynamics, pulmonary fluid balance, and indocyanine green clearance. Langenbecks Arch Sug 387;271–275CrossRefGoogle Scholar
  42. 42.
    Boussat S, Jacques T, Levy B, et al (2002) Intravascular volume monitoring and extravascular lung water in septic patients with pulmonary edema. Intensive Care Med 28:712–718CrossRefPubMedGoogle Scholar
  43. 43.
    Sakka SG, Reinhart K, Meier-Hellman A (2002) Prognostic value ofthe indocyanine green plasma disappearance rate in critically ill patients. Chest 122:1715–1720CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2005

Authors and Affiliations

  • A. B. J. Groeneveld
  • R. M. B. G. E. Breukers
  • J. Verheij

There are no affiliations available

Personalised recommendations