2.4 Conclusions
These studies demonstrate that noninvasive molecular imaging of protein-protein interactions may enable investigators to determine how intrinsic binding specificities of proteins are regulated in a wide variety of normal and pathophysiologic conditions. These tools provide a platform for detection of regulated and small molecule-induced protein-protein interactions in intact cells and living animals and should enable a wide range of novel applications in biomedi-cine, drug discovery, chemical genetics, and proteomics research.
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Piwnica-Worms, D., Luker, K.E. (2005). Imaging Protein-Protein Interactions in Whole Cells and Living Animals. In: Bogdanov, A.A., Licha, K. (eds) Molecular Imaging. Ernst Schering Research Foundation Workshop, vol 49. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-26809-X_2
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