Advertisement

Herpes Viruses in Ocular Inflammation

  • Bahram Bodaghi
  • Phuc LeHoang
Part of the Essentials in Ophthalmology book series (ESSENTIALS)

Keywords

Aqueous Humor Retinal Pigment Epithelial Cell Herpes Virus Anterior Uveitis Ocular Inflammation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Abe T, Sato M, Tamai M (1998) Correlation of varicella-zoster virus copies and final visual acuities of acute retinal necrosis syndrome. Graefes Arch Clin Exp Ophthalmol 236:747–752CrossRefPubMedGoogle Scholar
  2. 2.
    Abe T, Sato M, Tamai M (2000) Variable R1 region in varicella zoster virus in fulminant type of acute retinal necrosis syndrome. Br J Ophthalmol 84:193–198CrossRefPubMedGoogle Scholar
  3. 3.
    Abe T, Tsuchida K, Tamai M (1996) A comparative study of the polymerase chain reaction and local antibody production in acute retinal necrosis syndrome and cytomegalovirus retinitis. Graefes Arch Clin Exp Ophthalmol 234:419–424PubMedGoogle Scholar
  4. 4.
    Atherton S, Pesicka G, Streilein J (1987) Retinitis and deviant immune responses following intravitreal inoculation of HSV-1. Invest Ophthalmol Vis Sci 28:859–866PubMedGoogle Scholar
  5. 5.
    Barequet IS, Li Q, Wang Y, O'Brien TP, Hooks JJ, Stark WJ (2000) Herpes simplex virus DNA identification from aqueous fluid in Fuchs heterochromic iridocyclitis. Am J Ophthalmol 129:672–673CrossRefPubMedGoogle Scholar
  6. 6.
    Bassili S, Peyman G, Gebhardt B, Daun M, Ganibang J (1996) Detection of Epstein-Barr virus DNA by polymerase chain reaction in the vitreous of a patient with Vogt-Koyanagi-Harada syndrome. Retina 16:160–161PubMedGoogle Scholar
  7. 7.
    Bloch-Michel E, Dussaix E, Cerquetti P, Patarin D (1987) Possible role of cytomegalovirus in the etiology of the Posner-Schlossmann syndrome. Int Ophthalmol 11:95–96CrossRefPubMedGoogle Scholar
  8. 8.
    Bodaghi B, Goureau O, Topilko A, Zipeto D, Laurent L, Virelizier J, Michelson S (1999) Pathogenesis of human cytomegalovirus retinitis: replication in retinal pigment epithelial cells is regulated by IFN-induced indoleamine 2, 3-dioxygenase but not inducible NO-synthase. J Immunol 162:957–964PubMedGoogle Scholar
  9. 9.
    Bodaghi B, LeHoang P (2002) Testing ocular fluids in uveitis. Ophthalmol Clin North Am 15:271–279CrossRefPubMedGoogle Scholar
  10. 10.
    Bodaghi B, Rozenberg F, Cassoux N, Fardeau C, LeHoang P (2003) Non-necrotizing herpetic retinopathies masquerading as severe posterior uveitis. Ophthalmology 110:1737–1743PubMedGoogle Scholar
  11. 11.
    Bodaghi B, Slobbe-van Drunen M, Topilko A, et al. (1999) Entry of human cytomegalovirus into retinal pigment epithelial and endothelial cells by endocytosis. Invest Ophthalmol Vis Sci 40:2598–2607PubMedGoogle Scholar
  12. 12.
    Cassoux N, Lumbroso L, Bodaghi B, Zazoun L, Katlama C, LeHoang P (1999) Cystoid macular edema and cytomegalovirus retinitis in patients with HIV disease treated with highly active antiretroviral therapy. Br J Ophthalmol 83:47–49PubMedGoogle Scholar
  13. 13.
    Culbertson WW, Blumenkranz MS, Haines H, Gass DM, Mitchell KB, Norton EW (1982) The acute retinal necrosis syndrome, part 2: Histopathology and etiology. Ophthalmology 89:1317–1325PubMedGoogle Scholar
  14. 14.
    Cunningham ET Jr, Short GA, Irvine AR, Duker JS, Margolis TP (1996) Acquired immunodeficiency syndrome-associated herpes simplex virus retinitis. Clinical description and use of a polymerase chain reaction-based assay as a diagnostic tool. Arch Ophthalmol 114:834–840PubMedGoogle Scholar
  15. 15.
    De Boer JH, Verhagen C, Bruinenberg M, et al. (1996) Serologic and polymerase chain reaction analysis of intraocular fluids in the diagnosis of infectious uveitis. Am J Ophthalmol 121:650–658PubMedGoogle Scholar
  16. 16.
    Detrick B, Rhame J, Wang Y, Nagineni C, Hooks J (1996) Cytomegalovirus replication in human retinal pigment epithelial cells. Altered expression of viral early proteins. Invest Ophthalmol Vis Sci 37:814–825PubMedGoogle Scholar
  17. 17.
    Dunkel E, De Freitas D, Siegel M, Zau Q, Whitley R, Schaffer P (1993) A rabbit model for human cytomegalovirus induced chorioretinal disease. J Infect Dis 168:336–344PubMedGoogle Scholar
  18. 18.
    Fisher JP, Lewis ML, Blumenkranz M, et al. (1982) The acute retinal necrosis syndrome, part 1: Clinical manifestations. Ophthalmology 89:1309–1316PubMedGoogle Scholar
  19. 19.
    Forster DJ, Dugel PU, Frangieh GT, Liggett PE, Rao NA (1990) Rapidly progressive outer retinal necrosis in the acquired immunodeficiency syndrome. Am J Ophthalmol 110:341–348PubMedGoogle Scholar
  20. 20.
    Fox GM, Crouse CA, Chuang EL, Pflugfelder SC, Cleary TJ, Nelson SJ, Atherton SS (1991) Detection of herpesvirus DNA in vitreous and aqueous specimens by the polymerase chain reaction. Arch Ophthalmol 109:266–271PubMedGoogle Scholar
  21. 21.
    Freilich JM, Ryan EA, Lou PL, Kroll AJ, Brockhurst RJ, Harooni M (1996) Acute retinal necrosis syndrome: findings, management, and differential diagnosis. Int Ophthalmol Clin 36:141–146Google Scholar
  22. 22.
    Ganatra JB, Chandler D, Santos C, Kuppermann B, Margolis TP (2000) Viral causes of the acute retinal necrosis syndrome. Am J Ophthalmol 129:166–172CrossRefPubMedGoogle Scholar
  23. 23.
    Garweg J, Bohnke M (1997) Varicella-zoster virus is strongly associated with atypical necrotizing herpetic retinopathies. Clin Infect Dis 24:603–608PubMedGoogle Scholar
  24. 24.
    Gaynor BD, Margolis TP, Cunningham ET Jr (2000) Advances in diagnosis and management of herpetic uveitis. Int Ophthalmol Clin 40:85–109CrossRefGoogle Scholar
  25. 25.
    Gershon A, Steinberg S (1981) Antibody response to varicella-zoster virus and the role of antibody in host defense. Am J Med Sci 282:12–17PubMedGoogle Scholar
  26. 26.
    Goldberg DE, Wang H, Azen SP, Freeman WR (2003) Long term visual outcome of patients with cytomegalovirus retinitis treated with highly active antiretroviral therapy. Br J Ophthalmol 87:853–855CrossRefPubMedGoogle Scholar
  27. 27.
    Groh M, Seitz B, Schumacher S, Naumann G (1999) Detection of herpes simplex virus in aqueous humor in iridocorneal endothelial (ICE) syndrome. Cornea 18:359–360PubMedGoogle Scholar
  28. 28.
    Han DP, Lewis H, Williams GA, Mieler WF, Abrams GW, Aaberg TM (1987) Laser photocoagulation in the acute retinal necrosis syndrome. Arch Ophthalmol 105:1051–1054PubMedGoogle Scholar
  29. 29.
    Herpetic EDSG (1998) Acyclovir for the prevention of recurrent herpes simplex virus eye disease. N Engl J Med 339:300–306CrossRefPubMedGoogle Scholar
  30. 30.
    Hoang-Xuan T, Buchi E, Herbort C (1992) Oral acyclovir for herpes zoster ophthalmicus. Ophthalmology 99:1062–1071PubMedGoogle Scholar
  31. 31.
    Holbrook JT, Jabs DA, Weinberg DV, Lewis RA, Davis MD, Friedberg D (2003) Visual loss in patients with cytomegalovirus retinitis and acquired immunodeficiency syndrome before widespread availability of highly active antiretroviral therapy. Arch Ophthalmol 121:99–107PubMedGoogle Scholar
  32. 32.
    Holland G (1994) Executive committee of the American Uveitis Society. Standard diagnostic criteria for the acute retinal necrosis syndrome. Am J Ophthalmol 117:663–667PubMedGoogle Scholar
  33. 33.
    Holland G, Fang E, Glasgow B, et al. (1990) Necrotizing retinopathy after inoculation of murine cytomegalovirus in immunosuppressed adult mice. Invest Ophthalmol Vis Sci 31:2326–2334PubMedGoogle Scholar
  34. 34.
    Holland G, Tufail A, Jordan M (1996) Cytomegalovirus diseases. In: Pepose J, Holland G, Wilhelmus K (eds) Ocular infection and immunity. Mosby, St. Louis, pp 1088–1128Google Scholar
  35. 35.
    Hooks J, Kupfer C (1995) Herpes simplex virus in iridocorneal endothelial syndrome. Arch Ophthalmol 113:1226–1228Google Scholar
  36. 36.
    Itoh N, Matsumura N, Ogi A, Nishide T, Imai Y, Kanai H, Ohno S (2000) High prevalence of herpes simplex virus type 2 in acute retinal necrosis syndrome associated with herpes simplex virus in Japan. Am J Ophthalmol 129:404–405CrossRefPubMedGoogle Scholar
  37. 37.
    Jabs DA, Van Natta ML, Kempen JH, Reed Pavan P, Lim JI, Murphy RL, Hubbard LD (2002) Characteristics of patients with cytomegalovirus retinitis in the era of highly active antiretroviral therapy. Am J Ophthalmol 133:48–61CrossRefPubMedGoogle Scholar
  38. 38.
    Karavellas MP, Azen SP, MacDonald JC, et al. (2001) Immune recovery vitritis and uveitis in AIDS: clinical predictors, sequelae, and treatment outcomes. Retina 21:1–9CrossRefPubMedGoogle Scholar
  39. 39.
    Kaufman HE, Varnell ED, Thompson HW (1999) Latanoprost increases the severity and recurrence of herpetic keratitis in the rabbit. Am J Ophthalmol 127:531–536CrossRefPubMedGoogle Scholar
  40. 40.
    Knox CM, Chandler D, Short GA, Margolis TP (1998) Polymerase chain reaction-based assays of vitreous samples for the diagnosis of viral retinitis. Use in diagnostic dilemmas. Ophthalmology 105:37–44; discussion 44–45CrossRefPubMedGoogle Scholar
  41. 41.
    Kumano Y, Manabe J, Hamamoto M, Kawano Y, Minagawa H, Fukumaki Y, Inomata H (1995) Detection of varicella-zoster virus genome having a PstI site in the ocular sample from a patient with acute retinal necrosis. Ophthalmic Res 27:310–316PubMedGoogle Scholar
  42. 42.
    Labetoulle M, Kucera P, Ugolini G, Lafay F, Frau E, Offret H, Flamand A (2000) Neuronal pathways for the propagation of herpes simplex virus type 1 from one retina to the other in a murine model. J Gen Virol 81:1201–1210PubMedGoogle Scholar
  43. 43.
    Labetoulle M, Kucera P, Ugolini G, Lafay F, Frau E, Offret H, Flamand A (2000) Neuronal propagation of HSV1 from the oral mucosa to the eye. Invest Ophthalmol Vis Sci 41:2600–2606PubMedGoogle Scholar
  44. 44.
    Labetoulle M, Maillet S, Efstathiou S, Dezelee S, Frau E, Lafay F (2003) HSV1 latency sites after inoculation in the lip: assessment of their localization and connections to the eye. Invest Ophthalmol Vis Sci 44:217–225CrossRefPubMedGoogle Scholar
  45. 45.
    Levinson RD, Hooks JJ, Wang Y, Chiu MT, Kellaway J, Chan CC (1998) Triple viral retinitis diagnosed by polymerase chain reaction of the vitreous biopsy in a patient with Richter syndrome. Am J Ophthalmol 126:732–733CrossRefPubMedGoogle Scholar
  46. 46.
    Liu W, Kuppermann BD, Martin DF, Wolitz RA, Margolis TP (1998) Mutations in the cytomegalovirus UL97 gene associated with ganciclovir-resistant retinitis. J Infect Dis 177:1176–1181PubMedGoogle Scholar
  47. 47.
    Markomichelakis NN, Canakis C, Zafirakis P, Marakis T, Mallias I, Theodossiadis G (2002) Cytomegalovirus as a cause of anterior uveitis with sectoral iris atrophy. Ophthalmology 109:879–882CrossRefPubMedGoogle Scholar
  48. 48.
    Mocarski E (1993) Cytomegalovirus biology and replication. In: Roizman B, Lopez C (eds) The human herpesviruses. Raven Press, New York, pp 173–225Google Scholar
  49. 49.
    Mochizuki K, Matsushita H, Hiramatsu Y, Yanagida K (1998) Detection of varicella-zoster virus genome in the vitreous humor from two patients with acute retinal necrosis; lacking or having a PstI cleavage site. Jpn J Ophthalmol 42:208–212CrossRefPubMedGoogle Scholar
  50. 50.
    Nahmias A (1990) Sero-epidemiological and sociological patterns of herpes simplex virus infection in the world. Scand J Infect Dis (Suppl) 69:19–36Google Scholar
  51. 51.
    Oh J (1976) Primary and secondary herpes simplex uveitis in rabbits. Surv Ophthalmol 21:178–184CrossRefPubMedGoogle Scholar
  52. 52.
    Palay DA, Sternberg P Jr, Davis J, et al. (1991) Decrease in the risk of bilateral acute retinal necrosis by acyclovir therapy. Am J Ophthalmol 112:250–255PubMedGoogle Scholar
  53. 53.
    Pendergast SD, Werner J, Drevon A, Wiedbrauk DL (2000) Absence of herpesvirus DNA by polymerase chain reaction in ocular fluids obtained from immunocompetent patients. Retina 20:389–393CrossRefPubMedGoogle Scholar
  54. 54.
    Roizman B, Sears A (1996) Herpes simplex viruses and their replication. In: Fields B, Knipe D, Howley P (eds) Virology. Raven Publishers, Philadelphia, pp 2231–2295Google Scholar
  55. 55.
    See RF, Rao NA (2002) Cytomegalovirus retinitis in the era of combined highly active antiretroviral therapy. Ophthalmol Clin North Am 15:529–536, viiiCrossRefPubMedGoogle Scholar
  56. 56.
    Smith IL, Macdonald JC, Freeman WR, Shapiro AM, Spector SA (1999) Cytomegalovirus (CMV) retinitis activity is accurately reflected by the presence and level of CMV DNA in aqueous humor and vitreous. J Infect Dis 179:1249–1253CrossRefPubMedGoogle Scholar
  57. 57.
    Song MK, Azen SP, Buley A, et al. (2003) Effect of anti-cytomegalovirus therapy on the incidence of immune recovery uveitis in AIDS patients with healed cytomegalovirus retinitis. Am J Ophthalmol 136:696–702CrossRefPubMedGoogle Scholar
  58. 58.
    Spaide R, Sugin S, Yannuzzi L, DeRosa J (1991) Epstein-Barr virus in multifocal choroiditis and panuveitis. Am J Ophthalmol 112:410–413PubMedGoogle Scholar
  59. 59.
    Tran TH, Rozenberg F, Cassoux N, Rao NA, LeHoang P, Bodaghi B (2003) Polymerase chain reaction analysis of aqueous humor samples in necrotising retinitis. Br J Ophthalmol 87:79–83CrossRefPubMedGoogle Scholar
  60. 60.
    Urayama A, Yamada N, Sasaki T, et al. (1971) Unilateral acute uveitis with retinal periarteritis and detachment. Jpn J Ophthalmol 25:607–629Google Scholar
  61. 61.
    Van der Lelij A, Ooijman FM, Kijlstra A, Rothova A (2000) Anterior uveitis with sectoral iris atrophy in the absence of keratitis: a distinct clinical entity among herpetic eye diseases. Ophthalmology 107:1164–1170CrossRefPubMedGoogle Scholar
  62. 62.
    Van der Lelij A, Rothova A (1997) Diagnostic anterior chamber paracentesis in uveitis: a safe procedure? Br J Ophthalmol 81:976–979PubMedGoogle Scholar
  63. 63.
    Van Gelder R, Willig J, Holland G, Kaplan H (2001) Herpes simplex virus type 2 as a cause of acute retinal necrosis syndrome in young patients. Ophthalmology 108:869–876CrossRefPubMedGoogle Scholar
  64. 64.
    Van Gelder RN (2001) Applications of the polymerase chain reaction to diagnosis of ophthalmic disease. Surv Ophthalmol 46:248–258CrossRefPubMedGoogle Scholar
  65. 65.
    Verbraak FD, Galema M, van den Horn GH, Bruinenberg M, Luyendijk L, Danner SA, Kijlstra A (1996) Serological and polymerase chain reaction-based analysis of aqueous humor samples in patients with AIDS and necrotizing retinitis. Aids 10:1091–1099PubMedGoogle Scholar
  66. 66.
    Von Szily A (1924) Experimentelle endogene Infektionsübertragung von Bulbus zu Bulbus. Klin Monatsbl Augenheikl 72:593–602Google Scholar
  67. 67.
    Wand M, Gilbert CM, Liesegang TJ (1999) Latanoprost and herpes simplex keratitis. Am J Ophthalmol 127:602–604CrossRefPubMedGoogle Scholar
  68. 68.
    Weinberg D, Lyon A (1997) Repair of retinal detachments due to herpes varicella-zoster virus retinitis in patients with acquired immune deficiency syndrome. Ophthalmology 104:279PubMedGoogle Scholar
  69. 69.
    Whitcup SM, Fortin E, Lindblad AS, et al. (1999) Discontinuation of anticytomegalovirus therapy in patients with HIV infection and cytomegalovirus retinitis. JAMA 282:1633–1637CrossRefPubMedGoogle Scholar
  70. 70.
    Whitley R (1996) Herpes simplex viruses. In: Fields B, Knipe D, Howley P (eds) Virology. Raven Publishers, Philadelphia, pp 2297–2342Google Scholar
  71. 71.
    Yamamoto Y, Hill J (1986) HSV-1 recovery from ocular tissues after viral inoculation into the superior cervical ganglia. Invest Ophthalmol Vis Sci 27:1447–1452PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2005

Authors and Affiliations

  • Bahram Bodaghi
  • Phuc LeHoang

There are no affiliations available

Personalised recommendations