Primary Malignant Renal Parenchymal Epithelial Neoplasms in Adults

  • Raymond Oyen
  • Hendrik Van Poppel
  • Tania Roskams


Renal Cell Carcinoma Renal Mass Clear Cell Carcinoma Papillary Renal Cell Carcinoma Renal Oncocytoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Murphy WM, Beckwith JB, Farrow GM (1994) Tumors of the kidney. In: Murphey WM, Beckwith JB, Farrow GM (eds) Atlas of tumor pathology. Tumors of the kidney, bladder and related urinary structures. Armed Forces Institute of Pathology, Washington DC, pp 92–145Google Scholar
  2. 2.
    Barbaric ZL (1996) Imaging work-up: is it renal carcinoma and is it operable? Semin Urol Oncol 14:196–202PubMedGoogle Scholar
  3. 3.
    Pavlovich CP, Walther MM, Choyke PL, Pautler SE, Chang R, Linehan WM, Wood BJ (2002) Percutaneous radio frequency ablation of small renal tumors: initial results. J Urol 167: 10–15CrossRefPubMedGoogle Scholar
  4. 4.
    Uzzo RG, Novick AC (2001) Nephron-sparing surgery for renal tumors: indication, techniques and outcomes. J Urol 166: 6–11CrossRefPubMedGoogle Scholar
  5. 5.
    Zucchi A, Mearini L, Mearini E, Constantini E, Vivacqua C, Porena M (2003) Renal cell carcinoma: histological findings on surgical margins after nephron sparing surgery. J Urol 169:905–908PubMedGoogle Scholar
  6. 6.
    Novick AC (1998) Nephron-sparing surgery for renal cell carcinoma. Br J Urol 82:321–324PubMedGoogle Scholar
  7. 7.
    Weiss LM, Gelb AB, Medeiros LJ (1995) Adult renal epithelial neoplasms. Am J Clin Pathol 103:624–635PubMedGoogle Scholar
  8. 8.
    Cohen C, McCue PA, Derose PB (1988) Histogenesis of renal cell carcinoma and oncocytoma. An immunohistochemical study. Cancer 62:1946–1951PubMedGoogle Scholar
  9. 9.
    Fleming S, O’Donnell M (2000) Surgical pathology or renal epithelial neoplasms: recent advantages and current status. Histopathology 36:195–202CrossRefPubMedGoogle Scholar
  10. 10.
    Thoenes W, Störkel ST, Rumpelt HJ (1986) Histopathology and classification of renal cell tumors. Pathol Res Pract 181: 125–143PubMedGoogle Scholar
  11. 11.
    Kovacs G (1993) Molecular differential pathology of renal cell tumors. Histopathology 22:1–8PubMedGoogle Scholar
  12. 12.
    Dal Sin P, Polito P, Van den Berghe H (1998) Genetics of renal tumors. Pathologica 90:101–107PubMedGoogle Scholar
  13. 13.
    Hughson MD, Johnson LD, Silva FG, Kovacs G (1993) Nonpapillary and papillary renal cell carcinoma: a cytogenetic and phenotypic study. Mod Pathol 6:449–456PubMedGoogle Scholar
  14. 14.
    Kovacs G, Akhtar M, Beckwith BJ, Bugert P, Cooper CS, Delahunt B, Eble JN, Fleming S, Ljungberg B, Medeiros LJ, Moch H, Reuter VE, Ritz E, Roos G, Schmidt D, Srigley JR, Störkel S, Van Den Berg E, Zbar B (1997) The Heidelberg classification of renal cell tumours. J Pathol 183:131–133PubMedGoogle Scholar
  15. 15.
    Fleming S, O’Donnell M (2000) Surgical pathology of renal epithelial neoplasms: recent advantages and current status. Histopathology 36:195–202CrossRefPubMedGoogle Scholar
  16. 16.
    Fleming S (1993) The impact of genetics on the classification of renal carcinoma. Histopathology 22: 89–92PubMedGoogle Scholar
  17. 17.
    Choyke PL, Glenn GM, Walther MM, Zbar B, Linehan WM (2003) Hereditary renal cancers. Radiology 226:33–46PubMedGoogle Scholar
  18. 18.
    Takahashi K, Honda M, Okubo R, Hyodo H et al (1993) CT pixel mapping in the diagnosis of small angiomyolipomas of the kidneys. J Comput Assist Tomogr 17:98–101PubMedGoogle Scholar
  19. 19.
    Curry NS, Schnabel SI, Garvin AJ, Fish G (1990) Intratumoral fat in a renal oncocytoma mimicking angiomyolipoma. AJR 154:307–308PubMedGoogle Scholar
  20. 20.
    Hartman DS (1990) Overview of renal cystic disease. In: Pollack HM (ed) Clinical urography, vol 2. Saunders, Philadelphia, pp 1059–1062Google Scholar
  21. 21.
    Jinzaki M, Ohkuma K, Tanimoto A, Mukai M, Hiramatsu K, Murai M, Hata J (1998) Small solid renal lesions: usefulness of power Doppler US. Radiology 209:543–550PubMedGoogle Scholar
  22. 22.
    Ascenti G, Gaeta M, Magno C, Mazziotti S, Blandino A, Melloni D, Zimbaro G (2004) Contrast-enhanced second-harmonic sonography in the detection of pseudocapsule in renal cell carcinoma. AJR 182:1525–1530PubMedGoogle Scholar
  23. 23.
    Israel GM, Hindman N, Bosniak MA (2004) Evaluation of cystic renal masses: comparison of CT and MR imaging by using the Bosniak classification system. Radiology 231:365–371PubMedGoogle Scholar
  24. 24.
    Soyer P, Dufresne AC, Klein I, Barbagelatta M, Herve JM, Scherrer A (1997) Renal cell carcinoma of clear type: correlation of CT features with tumor size, architectural patterns and pathologic staging. Eur Radiol 7:224–229CrossRefPubMedGoogle Scholar
  25. 25.
    Birnbaum BA, Jacobs JE, Ramchandani P (1996) Multiphasic renal CT: comparison of renal mass enhancement during the corticomedullary and nephrographic phases. Radiology 200: 753–758PubMedGoogle Scholar
  26. 26.
    Szolar DH, Kammerhuber F, Altziebler S, Tillich M, Breinl E, Fotter R, Schreyer HH (1997) Multiphasic helical CT of the kidney: increased conspicuity for detection and characterization of small (<3-cm) renal masses. Radiology 202:211–217PubMedGoogle Scholar
  27. 27.
    Israel GM, Bosniak MA (2003) Calcification in cystic renal masses: is it important in diagnosis? Radiology 226:47–52PubMedGoogle Scholar
  28. 28.
    Walter C, Heindel W, Kreussell M, Kugel H, Jung G, Gindele A (2001) Fast sequences with fat suppression in breath-hold mode: new standard in contrast-enhanced Tl-weighted MR imaging of renal tumors? Eur Radiol 11: 2092–2098CrossRefPubMedGoogle Scholar
  29. 29.
    Oto A, Herts BR, Remer EM, Novick AC (1998) Inferior vena cava tumor thrombus in renal cell carcinoma: staging by MR imaging and impact on surgical treatment. AJR 171: 1619–1624PubMedGoogle Scholar
  30. 30.
    Mancilla-Jimenez R, Stanley RJ, Blath RA (1976) Papillary renal cell carcinomas. Cancer 38:2469–2480PubMedGoogle Scholar
  31. 31.
    Amin MB, Corless CL, Renshaw AA, Tickoo SK, Kubus J, Schultz DS (1997) Papillary (chromophil) renal cell carcinoma: histomorphologic characteristics and evaluation of conventional pathologic prognostic parameters in 62 cases. Am J Surg Pathol 21:621–635CrossRefPubMedGoogle Scholar
  32. 32.
    Lager DJ, Huston BJ, Timmerman TG, Bonsib SM (1995) Papillary renal tumors. Cancer 76:669–673PubMedGoogle Scholar
  33. 33.
    Lesavre A, Correas JM, Meran S, Grenier N, Vieillefond A, Hélénon O (2003) CT of papillary renal cell carcinomas with cholesterol necrosis mimicking angiomyolipomas. AJR 181: 143–145PubMedGoogle Scholar
  34. 34.
    Kovacs G (1989) Papillary renal cell carcinoma: a morphologic and cytogenic study of 11 cases. Am J Pathol 134:27–34PubMedGoogle Scholar
  35. 35.
    Kovacs G, Fuzesi L, Emmanuel A, Kung H (1991) Cytogenetics of papillary renal cell tumors. Genes Chromosom Cancer 3: 249–255PubMedGoogle Scholar
  36. 36.
    Lemaître L, Provost M, Sault MC (1990) Tumeurs papillaires du parenchyme rénal: particularités de l’imagerie. A propos de 18 observations. Rev Im Med 2:615–623Google Scholar
  37. 37.
    Oyen RH (1997) Renal parenchymal tumors. Presented on the NICER course on gastrointestinal and urogenital radiology. World Trade Center, Seville, Spain 1997Google Scholar
  38. 38.
    Macari M, Bosniak MA (1999) Delayed CT to evaluate renal masses incidentally discovered at contrast-enhanced CT: demonstration of vascularity with deenhancement. Radiology 213:674–680PubMedGoogle Scholar
  39. 39.
    Suh M, Coakley FV, Qayyum A, Yeh BM, Breiman RS, Lu Y (2003) Distinction of renal cell carcinomas from high-attenuation renal cysts at portal venous phase contrast-enhanced CT. Radiology 228:330–334PubMedGoogle Scholar
  40. 40.
    Shinmoto H, Yassa Y, Tanimoto A, Narimatsu Y, Jinzaki M, Hiaramatsu K, Mukai M (1998) Small renal cell carcinoma: MRI with pathologic correlation. J Magn Reson Imaging 8: 690–694PubMedGoogle Scholar
  41. 41.
    Thoenes W, Störkel ST, Rumpelt HJ (1985) Human chromophobic cell renal carcinoma. Virchows Arch B 48:207PubMedGoogle Scholar
  42. 42.
    Crotty TB, Farrow GM, Lieber MM (1995) Chromophobic cell renal carcinoma: clinicopathological features of 50 cases. J Urol 154:964–967CrossRefPubMedGoogle Scholar
  43. 43.
    Akhtar, Kardar H, Linjawi T, McClintock J, Ali MA (1995) Chromophobic cell carcinoma of the kidney: a clinicopathologic study of 21 cases. Am J Surg Pathol 19:1245–1256PubMedGoogle Scholar
  44. 44.
    Kovacs A, Storkel S, Thoenes W, Kovacs G (1992) Mitochondrial and chromosomal DNA alterations in human chromophobe renal cell carcinomas. J Pathol 167:273–277CrossRefPubMedGoogle Scholar
  45. 45.
    Renshaw AA, Henske EP, Loughlin KR, Shapiro C, Weinberg DS (1996) Aggressive variants of chromophobic renal cell carcinoma. Cancer 78:1756–1761CrossRefPubMedGoogle Scholar
  46. 46.
    Fleming S, Lewi HJE (1986) Collecting duct carcinoma of the kidney. Histopathology 10:1131–1141PubMedGoogle Scholar
  47. 47.
    Matz L, Latham B, Fabian VA, Vivian JB (1997) Collecting duct carcinoma of the kidney: a report of three cases and a review of the literature. Pathology 29:354–359PubMedGoogle Scholar
  48. 48.
    Füzesi L, Cober M, Mittermayer C (1992) Collecting duct carcinoma: cytogenetic characterization. Histopathology 21: 155–160PubMedGoogle Scholar
  49. 49.
    Swartz MA, Karth J, Schneider DT, Rodriguez R, Beckwith JB, Perlman EJ (2002) Renal medullary carcinoma: clinical, pathologic, immunohistological, and genetic analysis with pathogenetic implications. Urology 60:1083–1089CrossRefPubMedGoogle Scholar
  50. 50.
    Dimashkieh H, Choe J, Mutema G (2003) Renal medullary carcinoma. A report of 2 cases and review of the literature. Arch Pathol Lab Med 127:e135–e138PubMedGoogle Scholar
  51. 51.
    Fukuya T, Honda H, Goto K, Ono M et al (1996) Computed tomographic findings of Bellini duct carcinoma of the kidney. J Comput Assist Tomogr 20:399–403CrossRefPubMedGoogle Scholar
  52. 52.
    De Peralta-Venturina M, Moch H, Amin M, Tamboli P, Hailemariam S, Mihatsch M, Javidan J, Stricker H, Ro JY, Amin MB (2001) Sarcomatoid differentiation in renal cell carcinoma. A study of 101 cases. Am J Surg Pathol 25:275–284PubMedGoogle Scholar
  53. 53.
    Bell ET (1950) Renal disease. 2nd edn. Lea & Febiger, PhiladelphiaGoogle Scholar
  54. 54.
    Grignon DJ, Eble JN (1998) Papillary and metanephric adenoma of the kidneys. Semin Diagn Pathol 15:41–53PubMedGoogle Scholar
  55. 55.
    Davis CJ, Sesterhenn IA, Mostofi FK, Ho CK (1992) Renal oncocytoma; clinicopathological study of 166 patients. J Uro-genital Pathol 1:41–52Google Scholar
  56. 56.
    Klein MJ, Valensi QJ (1976) Proximal tubular adenoma of the kidney with so-called oncocytic features. Cancer 38:906–914PubMedGoogle Scholar
  57. 57.
    Zagoria RJ (1998) Renal masses. Diagnostic imaging features. Presented at the annual meeting of the Society of Uroradiology. Hamilton, Bermuda 1998Google Scholar
  58. 58.
    Amin MB, Crotty TB, Tickoo SK, Farrow GM (1997) Renal oncocytoma: a reappraisal of morphologic features with clinicopathologic findings in 80 cases. Am J Surg Pathol 21:1–12CrossRefPubMedGoogle Scholar
  59. 59.
    Davidson AJ, Hayes WS, Hartman DS, McCarthy WF, Davis CJ (1993) Renal oncocytoma and carcinoma: failure of differentiation with CT. Radiology 186:693–696PubMedGoogle Scholar
  60. 60.
    Harmon WJ, King BF, Lieber MM (1996) Renal oncocytoma: magnetic resonance imaging characteristics. J Urol 155: 863–867CrossRefPubMedGoogle Scholar
  61. 61.
    Rybicki FJ, Shu KM, Cibas ES, Fielding JR, van Sonnenberg E, Silverman SG (2003) Percutaneous biopsy of renal masses: sensitivity and negative predictive value stratified by clinical setting and size of masses. AJR 180:1281–1287PubMedGoogle Scholar
  62. 62.
    Neuzillet Y, Lechevallier E, Andre M, Daniel L, Coulange C (2004) Accuracy and clinical role of fine needle percutaneous biopsy with computerized tomography guidance of small (less than 4.0 cm) renal masses. J Urol 171:1802–1805CrossRefPubMedGoogle Scholar
  63. 63.
    Thompson IM, Peek M (1988) Improvement in survival of patients with renal cell carcinoma: the role of serendipitously detected tumor. J Urol 140:487–490PubMedGoogle Scholar
  64. 64.
    Pronet J, Tessler A, Brown J, Golimbu M, Bosniak M, Morales P (1991) Partial nephrectomy for renal cell carcinoma: indications, results and implications. J Urol 145:472–476PubMedGoogle Scholar
  65. 65.
    Van Poppel H, Bamelis B, Oyen R, Baert L (1998) Partial nephrectomy for renal cell carcinoma can achieve long-term tumor control. J Urol 160:674–678CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2005

Authors and Affiliations

  • Raymond Oyen
  • Hendrik Van Poppel
  • Tania Roskams

There are no affiliations available

Personalised recommendations